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    CONDITIONED PARTICULATE SUBSTRATE STRUCTURE AND METHOD FOR PARTICULATE SUBSTRATE CONDITIONING
    2.
    发明申请
    CONDITIONED PARTICULATE SUBSTRATE STRUCTURE AND METHOD FOR PARTICULATE SUBSTRATE CONDITIONING 审中-公开
    用于颗粒基质调节的条件化的基体结构和方法

    公开(公告)号：WO2003094599A1

    公开(公告)日：2003-11-20

    申请号：PCT/GB2003/001907

    申请日：2003-05-08

    Applicant: NEWCASTLE UNIVERSITY VENTURES LIMITED ,  JONES, Colin, John, Francis, Philip ,  LAMONT-BLACK, John ,  GLENDENNING, Stephanie

    Inventor： JONES, Colin, John, Francis, Philip ,  LAMONT-BLACK, John ,  GLENDENNING, Stephanie

    IPC: A01G9/10

    CPC classification number: A01G24/00

    Abstract: A conditionable particulate substrate structure, and in particular a growing medium (2) suitable for the growth of vegetable matter in a surface layer, is described. The structure has a particulate base of soil or the like, a generally planar electrokinetic geosynthetic upper electrode (6) disposed generally horizontally in a surface layer of the particulate base; a lower electrode (8) disposed within the base generally underneath and parallel to the upper electrode, and means to connect an electrical power source (11) between the two electrodes to apply a potential difference thereacross to drive an electro-osmotic process and thus to alter the moisture level in the vicinity of the upper electrode and further to generate gas at the upper electrode. A method for conditioning a substrate, and a method for the creation of a conditioned substrate, are also described.

    Abstract translation: 描述了一种可调式颗粒基底结构，特别是适用于表层中植物物质生长的生长介质（2）。 该结构具有土壤或类似物的颗粒基底，大致水平地布置在颗粒基底的表面层中的电动学合成上电极（6）; 下部电极（8），其设置在所述基座内部并且平行于所述上部电极;以及用于连接所述两个电极之间的电源（11）的装置，以在所述两个电极之间施加电位差以驱动电渗透过程， 改变上部电极附近的湿度水平，并进一步在上部电极产生气体。 还描述了用于调节基底的方法以及用于产生调节的基底的方法。

    A MORE PRIVATE TELECOMMUNICATION METHOD
    5.
    发明申请
    A MORE PRIVATE TELECOMMUNICATION METHOD 审中-公开
    更私人的电信方法

    公开(公告)号：WO2016038188A1

    公开(公告)日：2016-03-17

    申请号：PCT/EP2015/070825

    申请日：2015-09-11

    Applicant: IMINDS VZW ,  UNIVERSITEIT HASSELT ,  NEWCASTLE UNIVERSITY

    Inventor： SCHÖNING, Johannes ,  OLIVIER, Patrick ,  DUNPHY, Paul

    IPC: H04L12/58 ,  H04L29/08 ,  H04L29/06

    CPC classification number: H04L63/08 ,  G06F21/606 ,  H04L51/066 ,  H04L67/2823

    Abstract: The invention relates to telecommunication methods, computer program products, non-transitory machine readable storage medium, graphical user interfaces, usage of those methods and devices, in particular for communicating a message from a first location to a second location, the method comprising the steps of: (i) inputting on a first processing engine on said first location the message; (ii) visually deforming the message; (iii) transmitting said deformed message to said second location; (iv) receiving on a second processing engine said deformed message and displaying it; whereby the degree of deforming in the first processing engine is selected to still allow recognition of the message on the display by a second user of the second processing engine while substantially increasing the processing effort to be used for automated recognition of the message by third processing engines when they would also come in the possession of the deformed message.

    Abstract translation: 本发明涉及电信方法，计算机程序产品，非暂时性机器可读存储介质，图形用户界面，这些方法和设备的使用，特别是用于将消息从第一位置传送到第二位置，该方法包括步骤 （i）在所述第一位置的第一处理引擎上输入消息; （ii）视觉上使消息变形; （iii）将所述变形消息发送到所述第二位置; （iv）在第二处理引擎上接收所述变形的消息并显示它; 由此第一处理引擎中的变形度被选择为仍然允许第二处理引擎的第二用户在显示器上识别消息，同时显着增加用于由第三处理引擎自动识别消息的处理工作 当他们也会拥有变形的信息。

    FUEL CELL ELECTRODE
    7.
    发明申请
    FUEL CELL ELECTRODE 审中-公开

    公开(公告)号：WO2004021486A3

    公开(公告)日：2004-03-11

    申请号：PCT/GB2003/003715

    申请日：2003-08-27

    Applicant: NEWCASTLE UNIVERSITY VENTURES LIMITED ,  SCOTT, Keith ,  CHENG, Hua

    Inventor： SCOTT, Keith ,  CHENG, Hua

    IPC: H01M8/04

    Abstract: A fuel cell (1) having an electrode comprising an electrocatalyst (32) on a support, wherein the support is a mesh (30) of conductive material such as a metal, metal alloy and metal composite (e.g. titanium or titanium alloy), is disclosed, as well as a method of operating such a fuel cell by contacting a fuel and an oxidant on said electrode. The electrolyte of the fuel cell may be an ion exchange membrane.

    RESONANT SENSOR
    8.
    发明申请
    RESONANT SENSOR 审中-公开
    谐振传感器

    公开(公告)号：WO2002063264A2

    公开(公告)日：2002-08-15

    申请号：PCT/GB2002/000237

    申请日：2002-01-21

    Applicant: NEWCASTLE UNIVERSITY VENTURES LTD. ,  BURDESS, James, Stonehouse ,  MCNEIL, Calum, Jack

    Inventor： BURDESS, James, Stonehouse ,  MCNEIL, Calum, Jack

    IPC: G01L9/00

    CPC classification number: G01N29/12 ,  G01M3/16 ,  G01N29/022 ,  G01N29/036 ,  G01N2291/014 ,  G01N2291/0255 ,  G01N2291/0256 ,  G01N2291/101

    Abstract: A resonant sensor for determining structural property changes, in particular for detecting the presence of chemical or biological species, comprises a structure (2) mounted to be capable of resonating and having a cyclically symmetrical configuration with two independent degenerative modes of vibration of a common natural frequency (f), and means (24,26,28,30,32,34,36,38) for exciting the structure (2) to resonate according to the two degenerative modes, regions (8,12,16,20) of the structure (2) being modified such that, on changes in the structural properties of the modified regions (8,12,16,20), for example by the addition or subtraction of mass, the natural frequencies (f1, f2) of the two modes of vibration become different, the difference in frequencies (?f) being proportional to the change in structural properties.

    Abstract translation: 用于确定结构特性变化的谐振传感器，特别是用于检测化学或生物物质的存在，包括安装成能够谐振并具有周期性对称构型的结构（2），其具有两种独立的退化模式的共同天然 频率（f）和用于激励结构（2）根据两个退化模式共振的装置（24,26,28,30,32,34,36,38），区域（8,12,16,20） 所述结构（2）被修改为使得在修改的区域（8,12,16,20）的结构特性的改变上，例如通过加或减质量，固有频率（f1，f2）为 两种振动模式变得不同，频率差（Δf）与结构特性的变化成正比。

    FUSION PROTEINS
    9.
    发明申请
    FUSION PROTEINS 审中-公开

    公开(公告)号：WO2003057708A3

    公开(公告)日：2003-07-17

    申请号：PCT/GB2003/000078

    申请日：2003-01-10

    Applicant: NEWCASTLE UNIVERSITY VENTURES LIMITED ,  GOKCE, Isa ,  ANDERLUH, Gregor ,  LAKEY, Jeremy, Hugh

    Inventor： GOKCE, Isa ,  ANDERLUH, Gregor ,  LAKEY, Jeremy, Hugh

    IPC: C12N15/62

    Abstract: The present invention relates to fusion proteins (fusion polypeptides), particularly for use in expression and/or purification systems. The present inventors have found that the To1AIII domain has remarkable properties which are of particular use as a fusion protein partner to achieve high levels of expression in a host cell. In one aspect of the invention, a To1AIII domain or a functional homologue, fragment, or derivative thereof is located towards the N-terminus of the fusion polypeptide and a non-To1A polypeptide is located towards the C-terminus of the fusion polypeptide.

    BENZIMIDAZOLE COMPOUNDS
    10.
    发明申请
    BENZIMIDAZOLE COMPOUNDS 审中-公开
    苯并咪唑化合物

    公开(公告)号：WO1997004771A1

    公开(公告)日：1997-02-13

    申请号：PCT/GB1996001832

    申请日：1996-07-30

    Applicant: NEWCASTLE UNIVERSITY VENTURES LIMITED ,  GRIFFIN, Roger, John ,  CALVERT, Alan, Hilary ,  CURTIN, Nicola, Jane ,  NEWELL, David, Richard ,  GOLDING, Bernard, Thomas

    Inventor： NEWCASTLE UNIVERSITY VENTURES LIMITED

    IPC: A61K31/415

    CPC classification number: C07D235/06 ,  A61K31/4184 ,  A61K31/675 ,  C07D235/08 ,  C07D235/10 ,  C07D235/12 ,  C07D235/14 ,  C07D235/16 ,  C07D235/18

    Abstract: A range is disclosed of benzimidazole-4-carboxamide compounds (I) which can act as potent inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase or PARP enzyme (EC 2.4.2.30), and which thereby can provide useful therapeutic compounds for use in conjunction with DNA-damaging cytotoxic drugs or radiotherapy to potentiate the effects of the latter. In formula (I), R and R' may each be selected independently from hydrogen, alkyl, hydroxyalkyl (e.g. CH2CH2OH), acyl (e.g. acetyl or benzoyl) or an optionally substituted aryl (e.g. phenyl) or aralkyl (e.g. benzyl or carboxybenzyl) group. R is generally a substituted phenyl group in the most preferred compounds. The compounds may also be used in the form of pharmaceutically acceptable salts or pro-drugs.

    Abstract translation: 公开了苯并咪唑-4-甲酰胺化合物（I）的范围，其可以作为DNA修复酶聚（ADP-核糖）聚合酶或PARP酶（EC 2.4.2.30）的有效抑制剂，由此可以提供有用的治疗化合物 与DNA损伤性细胞毒性药物或放射治疗联用以增强后者的作用。 在式（I）中，R和R'可各自独立地选自氢，烷基，羟基烷基（例如CH 2 CH 2 OH），酰基（例如乙酰基或苯甲酰基）或任选取代的芳基（例如苯基）或芳烷基（例如苄基或羧基苄基） 组。 R通常是最优选的化合物中的取代的苯基。 化合物也可以以药学上可接受的盐或前药的形式使用。

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