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1.发明申请COUMARIN COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS 审中-公开用于治疗MYCOBACTERIAL感染的COUMARIN化合物公开(公告)号：WO2012137224A1
公开(公告)日：2012-10-11
申请号：PCT/IN2012/000242
申请日：2012-04-04
Applicant: UNIVERSITY OF DELHI , VALLABHBHAI PATEL CHEST INSTIUTE , PARMAR, Virinder Singh , PRASAD, Ashok Kumar , RAJ, Hanumantharao Guru , BOSE, Mridula , SHARMA, Sunil Kumar , TONDON, Rashmi , BAGHEL, Anil , KATHURIA, Abha , GUPTA, Garima , AGGARWAL, Neha
Inventor： PARMAR, Virinder Singh , PRASAD, Ashok Kumar , RAJ, Hanumantharao Guru , BOSE, Mridula , SHARMA, Sunil Kumar , TONDON, Rashmi , BAGHEL, Anil , KATHURIA, Abha , GUPTA, Garima , AGGARWAL, Neha
CPC classification number: A61K31/37 , A61K31/4704
Abstract: The present invention relates to method for treating mycobacterial infection/disease by administration of a therapeutically effective amount of compound of formula I.
Abstract translation: 本发明涉及通过给予治疗有效量的式I化合物来治疗分枝杆菌感染/疾病的方法。
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公开(公告)号：WO2011030353A3
公开(公告)日：2011-11-17
申请号：PCT/IN2010000594
申请日：2010-09-07
Applicant: UNIV DELHI , PARMAR VIRINDER SINGH , PRASAD ASHOK KUMAR , SAXENA RAJENDRA KUMAR , SHAKYA GAURAV
Inventor： PARMAR VIRINDER SINGH , PRASAD ASHOK KUMAR , SAXENA RAJENDRA KUMAR , SHAKYA GAURAV
IPC: C12P19/38
Abstract: The present invention provides a process for the regioselective acylation of nucleosides, said process comprising preparing solution of a nucleoside, an acylating agent and a lipase; subjecting said solution to incubation at a predetermined temperature and filtering off the enzyme to obtain the product
Abstract translation: 本发明提供了核苷区域选择性酰化的方法，所述方法包括制备核苷，酰化剂和脂肪酶的溶液; 使所述溶液在预定温度下温育并过滤掉酶以获得产物
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3.发明申请COUMARIN COMPOUNDS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES AND PROCESS FOR PREPARING THE SAME 审中-公开用于治疗心血管疾病的欧司素化合物及其制备方法
公开(公告)号：WO2009157020A1
公开(公告)日：2009-12-30
申请号：PCT/IN2009/000359
申请日：2009-06-23
Applicant: DELHI UNIVERSITY , VALLABHBHAI PATEL CHEST INSTITUTE , PARMAR, Virender Singh , RAJ, Hanumanthrao Guru , PRASAD, Ashok Kumar , JAIN, Subhash Chand
Inventor： PARMAR, Virender Singh , RAJ, Hanumanthrao Guru , PRASAD, Ashok Kumar , JAIN, Subhash Chand
CPC classification number: C07D311/16
Abstract: The present invention relates to compounds of Formula (I): wherein- X and Y represent O, S, NR'; R n represents alkyl, aryl, OR 1 , NH 2 , SR 1 , NR 1 R 2 . wherein R 1 , R 2 = H, alkyl, phenyl, aryl, OCOR 3 , SCOR 3 , NHCOR 3 , NR 1 COR 3 , etc. (wherein R 3 represents alkyl, phenyl, aryl, heteroaryl); R' and R" represent H, alkyl, phenyl, substituted phenyl, phenyloxy, substituted phenyloxy, amino, monosubstitutedamino, disubstitutedamino, aryl, heteroaryl, aryloxy, heteroaryloxy, alkoxy, thioalkyl, thioalkyloxy, halo and a process for preparing the same.
Abstract translation: 本发明涉及式（I）的化合物：其中X和Y表示O，S，NR'; Rn表示烷基，芳基，OR1，NH2，SR1，NR1R2。 其中R1，R2 = H，烷基，苯基，芳基，OCOR3，SCOR3，NHCOR3，NR1COR3等（其中R3表示烷基，苯基，芳基，杂芳基）; R'和R“表示H，烷基，苯基，取代的苯基，苯氧基，取代的苯氧基，氨基，单取代氨基，二取代氨基，芳基，杂芳基，芳氧基，杂芳氧基，烷氧基，硫代烷基，硫代烷氧基，卤素及其制备方法。
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4.发明申请DIHYDROPYRIDIMIDINONE COMPOUNDS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES AND PROCESS FOR PREPARING THE SAME 审中-公开用于治疗心血管疾病的二氢吲哚美辛酮化合物及其制备方法
公开(公告)号：WO2009150668A1
公开(公告)日：2009-12-17
申请号：PCT/IN2009/000344
申请日：2009-06-15
Applicant: DELHI UNIVERSITY , VALLABHBHAI PATEL CHEST INSTITUTE , PARMAR, Virender Singh , RAJ, Hanumanthrao Guru , PRASAD, Ashok Kumar
Inventor： PARMAR, Virender Singh , RAJ, Hanumanthrao Guru , PRASAD, Ashok Kumar
IPC: A01N43/54 , A61K31/505
CPC classification number: C07D239/22
Abstract: The present invention relates to a dihydropyrimidinone compound of formula (I) wherein X represents O, S, etc. and R' represents alkyl, alkoxy, thioalkyl, thioalkyloxy, phenyl, substituted phenyl, phenyloxy, substituted phenyloxy, amino, monosubstitutedamino, disubstitutedamino, aryl, heteroaryl, aryloxy, heteroaryloxy, halo; R'' represents alkoxy, phenyloxy, substituted phenyloxy, aryloxy, heteroaryloxy, halo, NR 1 R 2 and R n represents OR 1 , NH 2 , SR 1 , NR 1 R 2 ; R 1 , R 2 = H, alkyl, phenyl, aryl, OCOR 3 , SCOR 3 , NHCOR 3 , NR 1 COR 3 ; R 3 represents alkyl, phenyl, aryl, heteroaryl.
Abstract translation: 本发明涉及式（I）的二氢嘧啶酮化合物，其中X表示O，S等，R'表示烷基，烷氧基，硫代烷基，硫代烷氧基，苯基，取代的苯基，苯氧基，取代的苯氧基，氨基，单取代的氨基，二取代的氨基， 芳基，杂芳基，芳氧基，杂芳氧基，卤素; R“表示烷氧基，苯氧基，取代的苯氧基，芳氧基，杂芳氧基，卤素，NR1R2和Rn表示OR1，NH2，SR1，NR1R2; R1，R2 = H，烷基，苯基，芳基，OCOR3，SCOR3，NHCOR3，NR1COR3; R3表示烷基，苯基，芳基，杂芳基。
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公开(公告)号：WO2011030353A2
公开(公告)日：2011-03-17
申请号：PCT/IN2010/000594
申请日：2010-09-07
Applicant: UNIVERSITY OF DELHI , PARMAR, Virinder, Singh , PRASAD, Ashok, Kumar , SAXENA, Rajendra, Kumar , SHAKYA, Gaurav
IPC: C12P19/38
Abstract: The present invention provides a process for the regioselective acylation of nucleosides, said process comprising preparing solution of a nucleoside, an acylating agent and a lipase; subjecting said solution to incubation at a predetermined temperature and filtering off the enzyme to obtain the product
Abstract translation: 本发明提供了用于核苷的区域选择性酰化的方法，所述方法包括制备核苷，酰化剂和脂肪酶的溶液; 使所述溶液在预定温度下孵育并过滤掉酶以获得产物
