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公开(公告)号：WO2019123328A1
公开(公告)日：2019-06-27
申请号：PCT/IB2018/060362
申请日：2018-12-19
Applicant: PROBIOTICAL S.P.A.
Inventor： PANE, Marco , AMORUSO, Angela , FIORIO, Mirta , MAROTTA, Angela , FELIS, Giovanna , DEL CASALE, Antonio
IPC: A61K35/741 , A61K35/744 , A61K35/745 , A61P25/00
CPC classification number: A61K35/744 , A61K35/741 , A61K35/745
Abstract: The present invention refers to a composition for use in the treatment of sleep disorder, in particular, in the improvement of sleep quality. Furthermore, the present invention refers to a composition for use in the treatment of mood modulation.
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公开(公告)号：WO2018234994A1
公开(公告)日：2018-12-27
申请号：PCT/IB2018/054508
申请日：2018-06-19
Applicant: PROBIOTICAL S.P.A.
Inventor： MOGNA, Giovanni
IPC: A23L33/135 , A61K35/745 , A61K35/747
Abstract: The present invention relates to a bacterial composition and/or derivatives thereof whose biological activity has been specifically studied for the improvement of the state of health differentiated for male and female human subjects.
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3.发明申请
公开(公告)号：WO2018215940A1
公开(公告)日：2018-11-29
申请号：PCT/IB2018/053632
申请日：2018-05-23
Applicant: PROBIOTICAL S.P.A.
Inventor： MOGNA, Giovanni
Abstract: The present invention relates to a bacteriotherapy based on bacterial compositions for the treatment and/or the prevention of neurodegenerative diseases, wherein said composition comprises an effective amount of bacterial microorganisms belonging to the species Lactobacillus fermentum , Lactobacillus delbrueckii subsp. delbrueckii , Lactobacillus plantarum and Lactobacillus salivarius , and mixtures thereof.
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公开(公告)号：WO2018078599A2
公开(公告)日：2018-05-03
申请号：PCT/IB2017/056728
申请日：2017-10-30
Applicant: PROBIOTICAL S.P.A.
Inventor： MOGNA, Giovanni
Abstract: The present invention relates to a composition comprising probiotic bacteria for the curative or preventive treatment of metabolic syndrome, enlarged liver, non-alcoholic fatty liver disease (NAFLD) and/or non-alcoholic steatohepatitis (NASH) in a subject, and a pharmaceutical preparation or medical device or food supplement comprising said composition.
Abstract translation: 本发明涉及包含益生菌的组合物，其用于治疗或预防性治疗代谢综合征，肝脏扩大，非酒精性脂肪肝疾病（NAFLD）和/或非酒精性脂肪性肝炎（NASH） 在受试者中，以及包含所述组合物的药物制剂或医疗装置或食物补充剂。
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5.发明申请LACTIC ACID BACTERIAL COMPOSITION FOR THE SIMULTANEOUS TREATMENT OF VAGINAL INFECTIONS OF FUNGAL AND BACTERIAL ORIGIN 审中-公开乳酸菌细菌组合物同时治疗真菌和细菌感染的阴道感染
公开(公告)号：WO2017163217A1
公开(公告)日：2017-09-28
申请号：PCT/IB2017/051711
申请日：2017-03-24
Applicant: PROBIOTICAL S.P.A.
Inventor： MOGNA, Giovanni
IPC: A61K35/747 , A61P15/02
Abstract: The present invention relates to a pharmaceutical composition or a composition for a medical device or a composition for a food supplement (briefly, the composition (s) of the present invention) based on lactic acid bacteria belonging to the species Lactobacillus fermentum for vaginal and oral use for the simultaneous treatment of vaginal infections, disorders or diseases of fungal and bacterial origin. Specifically, the present invention relates to a said composition comprising pharmaceutical- and/or food- grade excipients and a mixture, which comprises or, alternatively, consists of at least a strain of bacteria belonging to the species Lactobacillus fermentum for vaginal and oral use for the simultaneous treatment of vaginal infections, disorders or diseases selected from candidiasis, vaginitis, vulvovaginitis or bacterial vaginosis.
Abstract translation: 本发明涉及基于乳酸菌的药物组合物或用于医疗器械的组合物或用于食品补充剂的组合物（简要地，本发明的组合物），其属于 发酵乳杆菌用于阴道和口服用于同时治疗阴道感染，病症或真菌和细菌来源的疾病。 具体而言，本发明涉及包含药物和/或食品级赋形剂和混合物的所述组合物，所述混合物包含至少一种属于发酵乳杆菌的细菌菌株，或者由其组成，用于阴道和口服用于 同时治疗选自念珠菌病，阴道炎，外阴阴道炎或细菌性阴道病的阴道感染，病症或疾病。
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Patent Agency Ranking6.发明申请COMPOSITION OF LACTIC BACTERIA FOR USE IN THE TREATMENT OF INFECTIONS DUE TO PROPIONIBACTERIUM ACNES AND IN PARTICULAR FOR ACNE 审中-公开乳酸菌的组合物用于治疗由丙酸杆菌引起的感染，特别是用于治疗感染
公开(公告)号：WO2017025936A2
公开(公告)日：2017-02-16
申请号：PCT/IB2016/054869
申请日：2016-08-12
Applicant: PROBIOTICAL S.P.A.
Inventor： MOGNA, Giovanni
IPC: A61K35/747 , A61P17/10 , A61P17/08
CPC classification number: A61K35/747 , A61K2300/00
Abstract: The present invention relates to selected strains of lactic bacteria for use in the treatment of infections caused by pathogenic bacteria belonging to the species Propionibacterium acnes, in particular for use in the preventive and/or curative treatment of dermatitis in general, seborrheic dermatitis, rosacea, eczema and acne. In addition, the present invention relates to a composition which comprises a mixture comprising or, alternatively, consisting of selected strains of lactic bacteria for use in the treatment of infections caused by pathogenic bacteria belonging to the species Propionibacterium acnes, in particular for use in the preventive and/or curative treatment of dermatitis in general, seborrheic dermatitis, rosacea, eczema and acne. The composition comprising said mixture of selected strains of lactic bacteria is formulated in a pharmaceutical form for oral use (novel food, supplement product or medical device or pharmaceutical composition) in the form of powder, dispersible powder, granulate, packets or stick, solution, spray solution, syrup, tablet, capsule, pill or lozenge; or for topical use (composition for medical device or pharmaceutical composition) in the form of cream, ointment, pomade, gel, hydrogel, dispersion, emulsion or spray to be used as such for skin applications, or for transdermal use even in the form of a band aid.
Abstract translation: 本发明涉及用于治疗属于痤疮丙酸杆菌属的致病细菌引起的感染的选择的乳酸菌株，特别是用于预防性和/或治疗性皮炎的治疗 一般来说，脂溢性皮炎，红斑痤疮，湿疹和痤疮。 此外，本发明涉及包含混合物的组合物，所述混合物包含选择的乳酸菌菌株或可选地由选择的乳酸菌菌株组成，用于治疗属于痤疮丙酸杆菌属的致病细菌引起的感染，特别是用于 一般皮炎的预防性和/或治愈性治疗，脂溢性皮炎，红斑痤疮，湿疹和痤疮。 包含乳酸菌选定菌株的所述混合物的组合物以粉末，可分散粉末，颗粒，小包或棒状形式，溶液形式用于口服使用的药物形式（新型食物，补充产品或医疗装置或药物组合物）配制， 喷雾溶液，糖浆，片剂，胶囊，丸剂或锭剂; 或局部使用（用于医疗装置或药物组合物的组合物），其以乳膏，软膏，润发油，凝胶，水凝胶，分散体，乳液或喷雾剂的形式用于皮肤应用，或用于透皮使用，即使 一个乐队援助。
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7.发明申请USE OF LACTOBACILLI INHIBITING GAS PRODUCING COLIFORM BACTERIA ISOLATED FROM INFANTS AFFECTED BY COLIC 审中-公开利用乳酸菌抑制烟草生成分泌细菌的气体从分类受影响的婴儿中分离
公开(公告)号：WO2012001440A1
公开(公告)日：2012-01-05
申请号：PCT/IB2010/001554
申请日：2010-06-28
Applicant: PROBIOTICAL S.P.A. , SCATIZZI, Gianna
Inventor： SCATIZZI, Gianna
CPC classification number: C12N1/20 , A61K35/747 , C12R1/225 , C12R1/25 , Y02A50/473
Abstract: The present invention relates to a composition comprising two probiotic strains of bacteria capable of performing an antioxidant and/or antibacterial and competitive action against species of coliform bacteria that produce gas by fermentation of sugar, in particular lactose, isolated from infants affected by colic.
Abstract translation: 本发明涉及一种组合物，其包含两种益生菌菌株，其能够对通过发生糖，特别是乳糖从大肠杆菌感染的婴儿分离而产生气体的大肠杆菌细菌的种类进行抗氧化和/或抗菌和抗竞争。
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8.发明申请
公开(公告)号：WO2009106536A3
公开(公告)日：2009-09-03
申请号：PCT/EP2009/052208
申请日：2009-02-25
Applicant: PROBIOTICAL S.P.A. , STROZZI, Gian Paolo , MOGNA, Giovanni , MOGNA, Luca
Inventor： STROZZI, Gian Paolo , MOGNA, Giovanni , MOGNA, Luca
IPC: A23C11/10
Abstract: The present invention relates to fermented soymilk and to a method for improving the organoleptic properties of fermented soymilk.
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9.发明申请
公开(公告)号：WO2021229433A1
公开(公告)日：2021-11-18
申请号：PCT/IB2021/054003
申请日：2021-05-11
Applicant: PROBIOTICAL S.P.A.
Inventor： MOGNA, Vera , PANE, Marco , AMORUSO, Angela , COSTAGLIOLA, Ciro
IPC: A61K35/00 , A61K35/744 , A61K35/747 , A61K31/00 , A61K45/06 , A61P27/02
Abstract: The present invention relates to mixtures, or compositions comprising said mixtures, comprising at least one bacterial strain, preferably at least one probiotic bacterial strain or a derivative thereof, as well as to the use of said mixtures or compositions in methods for the preventive and/or curative treatment of an inflammatory ocular and/or periocular lesion, preferably in methods for the treatment of ocular diseases such as dry eyes, eyelid allergy, conjunctivitis, blepharitis, meibonite, dacryoliths, stye, inflammatory lesions of ocular adnexa and associated symptoms.
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公开(公告)号：WO2021019491A1
公开(公告)日：2021-02-04
申请号：PCT/IB2020/057205
申请日：2020-07-30
Applicant: PROBIOTICAL S.P.A.
Inventor： MOGNA, Vera , PANE, Marco , AMORUSO, Angela
Abstract: The present invention relates to a cellular component homogenate in liquid form, as well as to a cellular component homogenate in solid form, preferably as sprayed powder. Furthermore, the present invention relates to a homogenisation process for the preparation of said cellular component homogenate in liquid form and said cellular component homogenate in solid form, preferably as sprayed powder. Lastly, the present invention relates to a composition comprising said cellular component homogenate in solid form and, optionally, one or more pharmaceutical or food grade or cosmetic additives and excipients, for use in the pharmaceutical, nutraceutical, medical devices, foods for special medical purposes, dietary supplements and food industry both in the human and veterinarian field, as well as for use in the cosmetics industry.
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