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    METHODS FOR IMPROVED ETHANOL PRODUCTION
    3.
    发明申请
    METHODS FOR IMPROVED ETHANOL PRODUCTION 审中-公开
    改进乙醇生产方法

    公开(公告)号：WO2014107515A1

    公开(公告)日：2014-07-10

    申请号：PCT/US2014/010080

    申请日：2014-01-02

    Applicant: BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY ON BEHALF OF SOUTHERN ILLINOIS UNIVERSITY EDWARDSVILLE ,  TRUPIA, Sabrina

    Inventor： TRUPIA, Sabrina

    IPC: C12P7/06 ,  C12P19/14

    CPC classification number: C12M21/12 ,  C12M23/58 ,  C12P7/10 ,  Y02E50/16 ,  Y02E50/17

    Abstract: Some embodiments provide a process for the production of ethanol. The process includes performing liquefaction, saccharification, and fermentation steps to produce ethanol from an organic material. In one embodiment, the liquefaction step may include disposing a carbon-containing material within a first vessel, adding at least one enzyme to the first vessel, and incubating the first vessel at a first temperature for a predetermined time period. Next, the saccharification step can include adding at least one enzyme to the first vessel and then incubating the first vessel at a second temperature to form a liquefact in the first vessel. Then, in some embodiments, the fermentation step includes removing the liquefact from the first vessel and transferring the liquefact to a second vessel. Once in the second vessel, at least one additional enzyme, at least one nutrient, and a plurality of yeast cells can be added to the second vessel. Then, the second vessel is incubated to promote fermentation.

    Abstract translation: 一些实施方案提供了生产乙醇的方法。 该方法包括进行液化，糖化和发酵步骤以从有机材料生产乙醇。 在一个实施方案中，液化步骤可以包括在第一容器内设置含碳材料，向第一容器中加入至少一种酶，并将第一容器在第一温度下孵育预定时间段。 接下来，糖化步骤可以包括向第一容器中加入至少一种酶，然后在第二温度下孵育第一容器以在第一容器中形成液化。 然后，在一些实施方案中，发酵步骤包括从第一容器中除去液化物并将液化转移到第二容器。 一旦在第二容器中，可以向第二容器中加入至少一种另外的酶，至少一种营养物和多种酵母细胞。 然后，将第二容器温育以促进发酵。

    INDOLE-DERIVED COMPOUND PRODUCTION
    6.
    发明申请
    INDOLE-DERIVED COMPOUND PRODUCTION 审中-公开
    吲哚衍生的化合物生产

    公开(公告)号：WO2016007521A3

    公开(公告)日：2016-01-14

    申请号：PCT/US2015/039392

    申请日：2015-07-07

    Applicant: BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY

    Inventor： ANTEROLA, Aldwin

    IPC: C12N15/09 ,  C09B7/02 ,  C07H21/04 ,  C12N1/21 ,  C12N15/52 ,  C12P17/10

    Abstract: Among the various aspects of the present disclosure is the provision of a transgenic organism, an artificial DNA construct, and methods for producing a transgenic organism for indigo, indirubin, and other indole-derived compound production. Another aspect of the present disclosure is the provision of a transgenic organism wherein the indole-derived compound imparts color to the transgenic organism or to a portion of the transgenic organism.

    Abstract translation: 在本公开的各个方面中，提供了转基因生物，人造DNA构建体以及用于生产靛蓝，靛玉红和其他吲哚衍生化合物生产的转基因生物的方法。 本公开的另一方面是提供转基因生物，其中吲哚衍生化合物赋予转基因生物或部分转基因生物以颜色。

    INHIBITION OF UBC9-MEDIATED CANCER CELL INVASION AND METASTASIS
    8.
    发明申请
    INHIBITION OF UBC9-MEDIATED CANCER CELL INVASION AND METASTASIS 审中-公开
    UBC9介导的癌细胞侵袭和METASTASIS的抑制作用

    公开(公告)号：WO2011084815A1

    公开(公告)日：2011-07-14

    申请号：PCT/US2010/061622

    申请日：2010-12-21

    Applicant: BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY ,  MO, Yin-Yuan

    Inventor： MO, Yin-Yuan

    IPC: C12N15/11

    CPC classification number: C12N15/1137 ,  C12N2310/11 ,  C12N2310/113 ,  C12N2310/14 ,  C12N2310/141 ,  C12N2310/3181 ,  C12N2310/3231

    Abstract: A method for inhibiting invasion or metastasis of cancer cells that contemplates enhancing the expression of miR-224 in those cells, particularly human breast cancer ceils is disclosed. The production of miR-224 can be enhanced by suppressing the expression of Ubc9 in rhose cancer cells. Expression of Ubc9 can be suppressed by administering to those cancer cells an effective amount of antisense Ubc9 having a sequence complementary to a portion of the coding region or a non-coding region of Ubc9 mRNA and has a length of 10 to about 170 bases.

    Abstract translation: 公开了一种抑制癌细胞侵袭或转移的方法，其意图增强miR-224在那些细胞，特别是人乳腺癌细胞中的表达。 通过抑制兔癌细胞中Ubc9的表达，可以增强miR-224的产生。 可以通过向这些癌细胞施用有效量的具有与编码区的一部分或Ubc9 mRNA的非编码区互补的序列并且具有10至约170个碱基的长度的Ubc9的表达来抑制Ubc9的表达。

    ANT-REFLECTIVE AND ANTI-SOILING COATINGS WITH SELF-CLEANING PROPERTIES
    9.
    发明申请
    ANT-REFLECTIVE AND ANTI-SOILING COATINGS WITH SELF-CLEANING PROPERTIES 审中-公开
    具有自清洁特性的防反射和防污涂层

    公开(公告)号：WO2010127034A1

    公开(公告)日：2010-11-04

    申请号：PCT/US2010/032823

    申请日：2010-04-28

    Applicant: SOUTHERN ILLINOIS UNIVERSITY CARBONDALE ,  DAVE, Bakul, Champaklal

    Inventor： DAVE, Bakul, Champaklal

    IPC: C07F7/12

    CPC classification number: C09D5/006 ,  C03C17/30 ,  C08G77/24 ,  C08L83/04 ,  C09D5/1662 ,  C08L83/00

    Abstract: The embodiments of the invention are directed to organosilane-based coating compositions having anti-reflective, anti-soiling, and self-cleaning properties; methods of forming of the coatings; and articles of manufacture that utilize the coatings. In some embodiments, the coating compositions comprise an organosilane or mixture of organosilanes, a solvent, optionally an acid catalyst, and optionally a low molecular weight polymer.

    Abstract translation: 本发明的实施方案涉及具有抗反射，抗污染和自清洁性能的有机硅烷基涂料组合物; 形成涂层的方法; 以及利用涂层的制品。 在一些实施方案中，涂料组合物包含有机硅烷或有机硅烷的混合物，溶剂，任选的酸催化剂和任选的低分子量聚合物。

    MICRORNA-MEDIATED REGULATION OF UBC9 EXPRESSION IN CANCER CELLS
    10.
    发明申请
    MICRORNA-MEDIATED REGULATION OF UBC9 EXPRESSION IN CANCER CELLS 审中-公开
    UBC9表达在癌细胞中的微阵列调控

    公开(公告)号：WO2010054331A1

    公开(公告)日：2010-05-14

    申请号：PCT/US2009/063751

    申请日：2009-11-09

    Applicant: BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY ,  MO, Yin-yuan

    Inventor： MO, Yin-yuan

    IPC: A61K31/7088 ,  C07H21/02

    CPC classification number: A61K31/7088

    Abstract: Novel small expressed microRNA molecules associated with physiological regulatory mechanisms and particularly in developmental control are provided herein. More particularly, the present invention relates to microRNA molecules that suppress cancerous cell growth and other cancer-related disorders by suppressing tumor promoting factors such as, for example, Ubc9. Further, it is contemplated that the use of the microRNA molecules hereof will improve the diagnoses, prevention and/or treatment and also the identification and development of pharmaceuticals that are effective in connection with cancer cell growth.

    Abstract translation: 本文提供了与生理调节机制相关的新型小表达的微小RNA分子，特别是在发育控制中。 更具体地，本发明涉及通过抑制肿瘤促进因子例如Ubc9来抑制癌细胞生长和其它癌症相关疾病的微小RNA分子。 此外，预期使用其中的微小RNA分子将改善与癌细胞生长有关的药物的诊断，预防和/或治疗以及鉴定和开发。

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