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公开(公告)号：WO2018130601A2
公开(公告)日：2018-07-19
申请号：PCT/EP2018/050629
申请日：2018-01-11
Applicant: STICHTING KATHOLIEKE UNIVERSITEIT , TECHNOLOGIESTICHTING STW NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK (NWO)
Inventor： MEIJS, Midas , MEIJER, Frederick J. Anton , MANNIESING, Rashindra
IPC: A61B6/00
Abstract: A system for extracting flow information from a dynamic volumetric angiography dataset is configured for segmenting (202) a vasculature structure by labeling certain voxels of the dynamic volumetric angiography dataset as belonging to the vasculature. For each of a plurality of the labeled voxels, (203) a voxel time value is calculated indicative of a time when a time sequence of a voxel of the dynamic volumetric angiography dataset satisfies a certain predetermined condition. A histogram is calculated (204) of the calculated voxel time values. The system determines (205) a time window having a lower voxel time value and an upper voxel time value, by fitting a model to the histogram, wherein the model defines the time window in terms of certain predetermined features of the histogram. The system associates (206) a first color to the lower voxel time value, and a second color to the upper voxel time value.
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公开(公告)号：WO2017135822A1
公开(公告)日：2017-08-10
申请号：PCT/NL2017/050069
申请日：2017-02-02
Applicant: TECHNISCHE UNIVERSITEIT DELFT , TECHNOLOGIESTICHTING STW
CPC classification number: B01D71/024 , B01D61/027 , B01D67/0072 , B01D2323/283 , B01D2323/42
Abstract: The present invention is in the field of a preparation of inorganic tight nanofiltration membranes with a cut-off
Abstract translation: 本发明属于无机紧间纳滤膜的制备领域，所述无机紧间纳滤膜具有使用原子层沉积的具有高渗透性<450Da的截止分子量，用所述方法获得的膜，以及 这种膜的应用。 无机膜（也称为陶瓷膜）用于水和废水处理，作为聚合物膜的替代品。 无机膜的优点是它们具有高机械强度，高耐化学性和耐热性，使用寿命长，并且可作为原料陶瓷材料回收利用。
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公开(公告)号：WO2005009125A1
公开(公告)日：2005-02-03
申请号：PCT/NL2004/000539
申请日：2004-07-27
Applicant: TECHNOLOGIESTICHTING STW , VAN DER PLAATS, Arjan , VERKERKE, Gijsbertus, Jacobus , RAKHORST, Gerhard , PLOEG, Rutger, Jan , 'T HART, Nils, Arnaud , LEUVENINK, Hendrik, Gerrit, Derk
Inventor： VAN DER PLAATS, Arjan , VERKERKE, Gijsbertus, Jacobus , RAKHORST, Gerhard , PLOEG, Rutger, Jan , 'T HART, Nils, Arnaud , LEUVENINK, Hendrik, Gerrit, Derk
IPC: A01N1/02
CPC classification number: A01N1/02 , A01N1/0247 , A01N1/0273
Abstract: A portable preservation apparatus of the cold storage type for a donor organ, comprising a cooling box provided with an organ chamber for receiving a donor organ in preservative fluid and a lid, wherein, on the side which operatively faces the organ chamber, the lid is provided with a connector which is detachably connected to the lid, which connector is provided with passages for one or more connecting pieces connected with the donor organ and one or more pipes connected with at least one perfusion pump, wherein the at least one perfusion pump is a miniature pump mounted at least partly in the lid and wherein the apparatus further comprises at least one oxygenator, an oxygen container, one or more electronic modules and a power supply module.
Abstract translation: 一种用于供体器官的冷藏型便携式保存装置，包括设置有用于接收防腐液体中的供体器官的器官腔的冷却箱和盖子，其中，在操作性地面向器官腔室的一侧，盖子是 设置有可拆卸地连接到盖的连接器，该连接器设置有用于与供体器官连接的一个或多个连接件的通道和与至少一个灌注泵连接的一个或多个管道，其中至少一个灌注泵是 至少部分地安装在所述盖中的微型泵，其中所述装置还包括至少一个氧合器，氧气容器，一个或多个电子模块和电源模块。
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公开(公告)号：WO2010133347A3
公开(公告)日：2011-01-13
申请号：PCT/EP2010003049
申请日：2010-05-19
Applicant: UNIV LEIDEN , TECHNOLOGIESTICHTING STW , ZALM DIEDERIK JOHANNES VAN DER , HEERES ERWIN CORNELIS , HESSELBERTH MARINUS BERNARDUS STEPHANUS , KATAN ALLARD JULES , ES MAARTEN HUBERTUS VAN
Inventor： ZALM DIEDERIK JOHANNES VAN DER , HEERES ERWIN CORNELIS , HESSELBERTH MARINUS BERNARDUS STEPHANUS , KATAN ALLARD JULES , ES MAARTEN HUBERTUS VAN
CPC classification number: B25J7/00 , G02B21/26 , H01J37/20 , H01J37/28 , H01J2237/20221 , H01J2237/20264 , H01J2237/208 , H02N2/028
Abstract: A nano-scale manipulator (10) comprises a mounting deck (11) and a frame (12), the deck (11) being moveably secured to the frame (12) by two flexural joints permitting movement of the deck relative to the frame in first and second respective, mutually orthogonal directions of movement. Manipulator (10) also includes at least one respective, elongate piezoelectric actuator (21, 22) for each of the flexural joints, each respective piezoelectric actuator (21, 22) being secured so as to interconnect the deck (11) and the frame (12) and being extensible and contractible in a direction that is parallel to one of the said directions of movement; and a source (23) of electrical power for causing operation of each piezoelectric actuator (21, 22). Each of the piezoelectric actuators (21, 22) also is free to flex in directions other than its direction of extension and contraction.
Abstract translation: 纳米级操纵器（10）包括安装板（11）和框架（12），板（11）通过两个弯曲接头可移动地固定到框架（12），允许板相对于框架 第一和第二相应的相互正交的运动方向。 操纵器（10）还包括用于每个弯曲接头的至少一个相应的细长压电致动器（21,22），每个相应的压电致动器（21,22）被固定以便将平台（11）和框架 并且在与所述移动方向中的一个方向平行的方向上可伸长和收缩; 和用于使每个压电致动器（21,22）工作的电源（23）。 每个压电致动器（21,22）也在其伸缩方向以外的方向上自由弯曲。
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公开(公告)号：WO2010024664A8
公开(公告)日：2010-03-04
申请号：PCT/NL2009/000165
申请日：2009-08-26
Applicant: TECHNISCHE UNIVERSITEIT DELFT , TECHNOLOGIESTICHTING STW , VAN SCHIEVEEN, Jeroen, Paul , SPRONCK, Josephus, Wilhelmus
Abstract: The invention relates to an actuator for positioning an object in a first direction of movement, comprising a base, at least three positioning members, wherein each of the at least three positioning members has a contact surface which is configured to bear against the object under prestress, and a control device to drive the at least three positioning members in friction drive mode. In addition, the actuator comprises at least one heating device which is connected to the control device, in which the at least one heating device is configured to heat the at least three positioning members, and prestressing means to provide the prestress with which the contact surfaces of the at least three positioning members bear against the object, in which the at least three positioning members are of elongate design and are connected by one end to the base, and in which the contact surface is situated near the other end of the at least three positioning members, and in which the at least three positioning members are made from a material which expands under the effect of heat.
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公开(公告)号：WO2010024664A1
公开(公告)日：2010-03-04
申请号：PCT/NL2009000165
申请日：2009-08-26
Applicant: UNIV DELFT TECH , TECHNOLOGIESTICHTING STW , VAN SCHIEVEEN JEROEN PAUL , SPRONCK JOSEPHUS WILHELMUS
Inventor： VAN SCHIEVEEN JEROEN PAUL , SPRONCK JOSEPHUS WILHELMUS
CPC classification number: B81B3/0024 , B81B2201/047 , B81B2203/051
Abstract: The invention relates to an actuator for positioning an object in a first direction of movement, comprising a base, at least three positioning members, wherein each of the at least three positioning members has a contact surface which is configured to bear against the object under prestress, and a control device to drive the at least three positioning members in friction drive mode. In addition, the actuator comprises at least one heating device which is connected to the control device, in which the at least one heating device is configured to heat the at least three positioning members, and prestressing means to provide the prestress with which the contact surfaces of the at least three positioning members bear against the object, in which the at least three positioning members are of elongate design and are connected by one end to the base, and in which the contact surface is situated near the other end of the at least three positioning members, and in which the at least three positioning members are made from a material which expands under the effect of heat.
Abstract translation: 用于在第一运动方向上定位物体的致动器技术领域本发明涉及一种用于在第一运动方向上定位物体的致动器，该致动器包括基座，至少三个定位构件，其中，至少三个定位构件中的每一个具有接触表面，该接触表面构造成在预应力 以及以摩擦驱动模式驱动所述至少三个定位构件的控制装置。 此外，致动器包括至少一个加热装置，该加热装置连接到控制装置，其中至少一个加热装置构造成加热至少三个定位构件，以及预加应力装置提供预应力，该接触面 所述至少三个定位构件中的至少三个定位构件抵靠所述物体，其中所述至少三个定位构件具有细长设计并且通过一端连接到所述基部，并且其中所述接触表面位于所述至少三个定位构件的所述另一端附近 三个定位构件，并且其中所述至少三个定位构件由在热的作用下膨胀的材料制成。
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公开(公告)号：WO2007058527A3
公开(公告)日：2007-09-20
申请号：PCT/NL2006000575
申请日：2006-11-17
Applicant: AMC AMSTERDAM , TECHNOLOGIESTICHTING STW , BERKHOUT BENJAMIN , DAS ATZE TAEDE
Inventor： BERKHOUT BENJAMIN , DAS ATZE TAEDE
IPC: C12N15/63 , A61K48/00 , C07K14/245 , C12N7/01 , C12N15/10 , C12N15/867
CPC classification number: C12N7/00 , A61K39/12 , A61K39/21 , A61K2039/5254 , C12N15/635 , C12N2740/16034 , C12N2740/16061 , C12N2830/003
Abstract: The invention provides improved rtTA and single chain rtTA variants and uses thereof for inducible expression of a nucleic acid of interest. Nucleic acid sequences comprising an improved rtTA and/or sc rtTA sequence according to the invention are also provided, as well as vectors, replicons and cells comprising such nucleic acid sequences.
Abstract translation: 本发明提供改进的rtTA和单链rtTA变体及其用于诱导性表达感兴趣的核酸的用途。 还提供了包含根据本发明的改进的rtTA和/或sc rtTA序列的核酸序列，以及载体，复制子和包含该核酸序列的细胞。
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公开(公告)号：WO2007058527A2
公开(公告)日：2007-05-24
申请号：PCT/NL2006/000575
申请日：2006-11-17
Applicant: ACADEMISCH MEDISCH CENTRUM , TECHNOLOGIESTICHTING STW , BERKHOUT, Benjamin , DAS, Atze Taede
Inventor： BERKHOUT, Benjamin , DAS, Atze Taede
IPC: C12N15/63 , C12N15/867 , C12N15/10 , C12N7/01 , C07K14/245 , A61K48/00
CPC classification number: C12N7/00 , A61K39/12 , A61K39/21 , A61K2039/5254 , C12N15/635 , C12N2740/16034 , C12N2740/16061 , C12N2830/003
Abstract: The invention provides improved rtTA and single chain rtTA variants and uses thereof for inducible expression of a nucleic acid of interest. Nucleic acid sequences comprising an improved rtTA and/or sc rtTA sequence according to the invention are also provided, as well as vectors, replicons and cells comprising such nucleic acid sequences.
Abstract translation: 本发明提供了改进的rtTA和单链rtTA变体及其用于诱导表达目的核酸的用途。 还提供了包含根据本发明的改进的rtTA和/或scTTA序列的核酸序列，以及包含此类核酸序列的载体，复制子和细胞。
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公开(公告)号：WO2018132006A1
公开(公告)日：2018-07-19
申请号：PCT/NL2018/050022
申请日：2018-01-12
Applicant: TECHNISCHE UNIVERSITEIT DELFT , TECHNOLOGIESTICHTING STW
Abstract: A digitally-controlled power amplifier (DPA) includes a radio frequency digital-to-analog converter (RF-DAC) constructed from nonlinearly weighted PA segments, a multiphase RF drive signal generator that drives the PA segments, and overdrive voltage control circuitry. The nonlinear weighting of the PA segments intrinsically compensates for amplitude-code-word dependent amplitude distortion (ACW-AM distortion) involved in the operation of the RF-DAC and the multiphase RF drive signal generator facilitates ACW-dependent phase distortion (ACW-PM distortion) reduction, thus obviating the need for complicated and efficiency-degrading digital predistortion. The overdrive voltage control circuitry is used to fine tune the RF output of the DPA and compensate for other non-idealities and external influences such as process, voltage, temperature (PVT), frequency and/or load impedance variations.
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公开(公告)号：WO2011093708A1
公开(公告)日：2011-08-04
申请号：PCT/NL2011/050057
申请日：2011-01-28
Applicant: TECHNOLOGIESTICHTING STW , TECHNISCHE UNIVERSITEIT DELFT , MAKINWA, Kofi Afolabi Anthony , KASHMIRI, Sayyed Mahdi
Inventor： MAKINWA, Kofi Afolabi Anthony , KASHMIRI, Sayyed Mahdi
CPC classification number: H03L1/022 , H03L7/08 , H03L2207/50
Abstract: An electrothermal frequency-locked loop (EFLL) circuit is described. This EFLL circuit includes an oscillator in a feedback loop. A drive circuit in the EFLL circuit generates a first signal having a fundamental frequency, and an electrothermal filter (ETF) in the EFLL circuit provides a second signal based on the first signal. This second signal has the fundamental frequency and a phase (relative to the first signal) that corresponds to a temperature- dependent time constant of the ETF. Moreover, a sensing component in the EFLL circuit determines a parameter associated with a temperature of the ETF. For example, the parameter may be the temperature or may be other than the temperature, such as the fundamental frequency and/or the phase of the second signal. Furthermore, the EFLL circuit includes a compensation circuit that compensates for frequency changes associated with changes in the temperature based at least on the parameter so that the fundamental frequency is approximately independent of the temperature.
Abstract translation: 描述了一种电热锁相环（EFLL）电路。 该EFLL电路包括反馈回路中的振荡器。 EFLL电路中的驱动电路产生具有基频的第一信号，并且EFLL电路中的电热滤波器（ETF）基于第一信号提供第二信号。 该第二信号具有对应于ETF的温度相关时间常数的基频和相位（相对于第一信号）。 此外，EFLL电路中的感测部件确定与ETF的温度相关联的参数。 例如，该参数可以是温度，也可以是除了第二信号的基频和/或相位之外的温度。 此外，EFLL电路包括补偿电路，其补偿与至少基于参数的温度变化相关联的频率变化，使得基本频率近似于温度。
