公开(公告)号：WO2022215038A1

公开(公告)日：2022-10-13

申请号：PCT/IB2022/053295

申请日：2022-04-07

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： GUO, Xuexue ,  VAN LENGERICH, Henrik B. ,  FISHMAN, Joshua M. ,  STENSVAD, Karl K. ,  BEDOYA, Cedric ,  NELSON, Caleb T. ,  NICCUM, Kayla C. ,  WHEATLEY, John A. ,  SOLOMON, Jeffrey L. ,  SHAVER, Jonah

IPC: G01N21/64 ,  G01N33/543

Abstract: Luminescent imaging films (100) for fluorescent enhancement and methods of making and using the same are provided. The films (100) include a flexible carrier layer (1109, and a pattern of photonic structure (120) disposed on the flexible carrier layer, which is interspersed with an anti-biofouling material (130) to provide a pattern of analyte sites (132). The pattern of photonic structure includes a patterned high-refractive-index dielectric material surface (123) so as to provide resonance at the excitation or emission wavelength to enhance a fluorescence signal from labeled analytes.