Abstract:
A metered dose inhaler equipped with a metering valve and having an aerosol canister containing a pharmaceutical composition comprising propellant, ethanol, citric acid, and tiotropium or a pharmaceutically acceptable salt or solvate thereof dissolved in the composition, wherein the aerosol canister has an internal surface that is a non-metal material that is in contact with the pharmaceutical composition.
Abstract:
A composition comprising particulate fluticasone or a pharmaceutically acceptable salt or solvate thereof, particulate vilanterol trifenatate, at least one of 1,1,1,2,3,3,3-heptafluoropropane and 1,1,1, 2-tetrafluoroethane.
Abstract:
Compositions containing tiotropium or a pharmaceutically acceptable salt or solvate thereof, citric acid or a salt thereof, glycerol, ethanol, and a propellant, as well as aerosol canisters and inhalers containing the same. Methods of manufacturing and using the compositions, aerosol canisters, and inhalers.