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    EXTRAVASCULAR DEVICES SUPPORTING AN ARTERIOVENOUS FISTULA
    4.
    发明申请
    EXTRAVASCULAR DEVICES SUPPORTING AN ARTERIOVENOUS FISTULA 审中-公开
    支持异位异常的超声波装置

    公开(公告)号：WO2016003922A1

    公开(公告)日：2016-01-07

    申请号：PCT/US2015/038355

    申请日：2015-06-29

    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

    Inventor： CONSIGNY, Paul ,  ELI, Erik ,  PACETTI, Stephen D. ,  TROLLSAS, Mikael ,  STANKUS, John

    IPC: A61M1/36

    CPC classification number: A61M1/3655 ,  A61B2017/1107 ,  A61B2017/1135

    Abstract: A medical device for being used as an extravascular device to support vein maturation following the formation of an arteriovenous fistula. The device (10) comprises a first tubular member (12) having ends; and a second tubular member (15a, 15b) connected to the first tubular member between the ends and extending from the second tubular member at a take-off angle less than about 45 degrees.

    Abstract translation: 用作血管外装置以在形成动静脉瘘后支持静脉成熟的医疗装置。 装置（10）包括具有端部的第一管状构件（12） 以及在端部之间连接到第一管状构件并且以小于约45度的起飞角度从第二管状构件延伸的第二管状构件（15a，15b）。

    STENT WITH EASED CORNER FEATURE
    5.
    发明申请
    STENT WITH EASED CORNER FEATURE 审中-公开
    具有拐杖特征的STENT

    公开(公告)号：WO2015006073A1

    公开(公告)日：2015-01-15

    申请号：PCT/US2014/044638

    申请日：2014-06-27

    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

    Inventor： PACETTI, Stephen D. ,  RAPOZA, Richard

    IPC: A61F2/915

    CPC classification number: A61F2/89 ,  A61F2/82 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/9155 ,  A61F2230/0054 ,  Y10T29/49995

    Abstract: An implantable stent includes a plurality of rings. At least a distal end ring has an eased corner feature formed in the polymer substrate at a radially outward, distal-facing corner of the ring while relatively sharp corners of the polymer substrate are maintained in radially inward corners of the ring.

    Abstract translation: 可植入支架包括多个环。 至少一个远端环具有形成在聚合物基底中位于环的径向向外的远侧面角处的易折角特征，而聚合物基底的相对尖锐的角保持在环的径向向内的拐角处。

    BIORESORBABLE SCAFFOLD FOR NEUROLOGIC DRUG DELIVERY
    6.
    发明申请
    BIORESORBABLE SCAFFOLD FOR NEUROLOGIC DRUG DELIVERY 审中-公开
    用于神经系统药物递送的生物可利用药物

    公开(公告)号：WO2014182696A2

    公开(公告)日：2014-11-13

    申请号：PCT/US2014/036967

    申请日：2014-05-06

    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

    Inventor： MAZER, Terry B. ,  PACETTI, Stephen D. ,  LORD, Brenna H.

    IPC: A61L31/06

    CPC classification number: A61L31/148 ,  A61L31/06 ,  A61L31/146 ,  A61L31/16 ,  A61L33/0011 ,  A61L33/0047 ,  A61L2300/254 ,  A61L2300/256 ,  A61L2300/416 ,  A61L2300/45 ,  A61L2300/604 ,  C08L67/04

    Abstract: Bioresorbable scaffolds and methods of treatment with such scaffolds for neurologic disorders including Parkinson's disease, Huntington's disease, Alzheimer's disease, and brain neoplasms are disclosed. The bioresorbable scaffold includes a bioresorbable body and an active agent or drug associated with the body for treating or ameliorating the neurological disorder. The bioresorbable scaffold is implanted in the neurological vasculature brain or brain tissue to provide localized delivery of the drug or active agent. Embodiments of the invention include scaffolds that are partially bioresorbable or completely bioresorbable.

    Abstract translation: 公开了生物可吸收的支架和用这种支架治疗包括帕金森病，亨廷顿舞蹈症，阿尔茨海默病和脑肿瘤的神经障碍的方法。 生物可吸收支架包括生物可吸收体和与身体相关联的用于治疗或改善神经障碍的活性剂或药物。 将生物可吸收的支架植入神经系统的脉管系统脑或脑组织中以提供药物或活性剂的局部递送。 本发明的实施方案包括部分生物可再吸收或完全生物可再吸收的支架。

    RADIOPAQUE INTRALUMINAL STENTS COMPRISING COBALT-BASED ALLOYS CONTAINING ONE OR MORE PLATINUM GROUP METALS, REFRACTORY METALS, OR COMBINATIONS THEREOF
    7.
    发明申请
    RADIOPAQUE INTRALUMINAL STENTS COMPRISING COBALT-BASED ALLOYS CONTAINING ONE OR MORE PLATINUM GROUP METALS, REFRACTORY METALS, OR COMBINATIONS THEREOF 审中-公开
    包含含有一种或多种铂族金属，碱金属或其组合的基于钴的合金的放射性体系

    公开(公告)号：WO2014159743A1

    公开(公告)日：2014-10-02

    申请号：PCT/US2014/024953

    申请日：2014-03-12

    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS, INC.

    Inventor： KRAMER-BROWN, Pamela A. ,  CALVERT, Kayla L. ,  SIMPSON, John A. ,  PACETTI, Stephen D. ,  LEACH, Austin M.

    IPC: A61L31/02 ,  A61L31/18 ,  A61F2/82 ,  C22C19/07

    CPC classification number: A61L31/022 ,  A61F2/82 ,  A61F2250/0098 ,  A61L31/18 ,  C22C5/04 ,  C22C19/007 ,  C22C19/07 ,  C22C30/00

    Abstract: Embodiments are directed to radiopaque implantable structures (e.g., stents) formed of cobalt-based alloys that comprise cobalt, chromium and one or more platinum group metals, refractory metals, precious metals, or combinations thereof. Platinum group metals include platinum, palladium, ruthenium, rhodium, osmium, and iridium. Refractory metals include zirconium, niobium, rhodium, molybdenum, hafnium, tantalum, tungsten, rhenium, and precious metals include silver and gold. In one embodiment, the one or more included platinum group or refractory metals substitute at least partially for nickel, such that the alloy exhibits reduced nickel content, or is substantially nickel free. The stents exhibit improved radiopacity as compared to similar alloys including greater amounts of nickel.

    Abstract translation: 实施例涉及由包含钴，铬和一种或多种铂族金属，难熔金属，贵金属或其组合的钴基合金形成的不透射线的可植入结构（例如，支架）。 铂族金属包括铂，钯，钌，铑，锇和铱。 耐火金属包括锆，铌，铑，钼，铪，钽，钨，铼，贵金属包括银和金。 在一个实施方案中，一种或多种包括的铂族或难熔金属至少部分地代替镍，使得该合金显示出降低的镍含量或基本上不含镍。 与包括更大量的镍的类似合金相比，支架表现出改善的射线不透性。

    IMPLANTABLE PROSTHESIS HAVING THROUGH-HOLES
    8.
    发明申请
    IMPLANTABLE PROSTHESIS HAVING THROUGH-HOLES 审中-公开
    具有通透性的可植入物

    公开(公告)号：WO2011123306A1

    公开(公告)日：2011-10-06

    申请号：PCT/US2011/029656

    申请日：2011-03-23

    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC. ,  PACETTI, Stephen D.

    Inventor： PACETTI, Stephen D.

    IPC: A61F2/90 ,  A61F2/00 ,  A61F2/02

    CPC classification number: A61F2/90 ,  A61F2/915 ,  A61F2002/91575 ,  A61F2210/0004 ,  A61F2230/0054 ,  A61F2240/001 ,  A61F2250/0068 ,  B33Y80/00

    Abstract: A prosthesis (10) for intraluminal drug delivery can comprise a plurality of interconnected struts and links (12, 14) that form a tubular structure. The struts and links can have luminal surfaces facing radially inward, abluminal surfaces facing radially outward, and side surfaces connecting the luminal surfaces to the abluminal surfaces. At least some of the struts and links have through-holes (50T) in the side surfaces. At least some of the through-holes contain a drug, which can be carried in a polymer matrix.

    Abstract translation: 用于腔内药物递送的假体（10）可以包括形成管状结构的多个互连的支柱和连杆（12,14）。 支柱和连杆可以具有朝向径向向内的腔表面，面向径向外侧的腹膜表面以及将管腔表面连接到腔外表面的侧表面。 至少一些支柱和连杆在侧面具有通孔（50T）。 至少一些通孔含有可以在聚合物基质中携带的药物。

    IMPLANTABLE PROSTHESIS WITH DEPOT RETENTION FEATURE
    9.
    发明申请
    IMPLANTABLE PROSTHESIS WITH DEPOT RETENTION FEATURE 审中-公开
    具有深层保留特征的可植入性

    公开(公告)号：WO2011123282A1

    公开(公告)日：2011-10-06

    申请号：PCT/US2011/029305

    申请日：2011-03-22

    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC. ,  PACETTI, Stephen D. ,  KERRIGAN, Cameron K.

    Inventor： PACETTI, Stephen D. ,  KERRIGAN, Cameron K.

    IPC: A61F2/82 ,  A61F2/90 ,  A61F2/00

    CPC classification number: A61F2/91 ,  A61F2/915 ,  A61F2210/0004 ,  A61F2210/0076 ,  A61F2230/0013 ,  A61F2250/0068 ,  B33Y80/00 ,  Y10T29/49826

    Abstract: A prosthesis for intraluminal drug delivery can comprise a plurality of interconnected struts that form a tubular scaffold structure. The struts include through-holes (50) with an inner surface configured to retain a bioabsorbable depot. The bioabsorbable depot includes a drug-polymer composition that hydrolytically degrades upon implantation. The inner surface of the through-hole can be an entirely smooth and continuous area that is concave or convex, with no geometric discontinuities. The inner surface of the through-hole can include any number of constricted and distended regions to form grooves of a size and shape carefully selected to engage a corresponding geometric feature of the bioabsorbable depot.

    Abstract translation: 用于管腔内药物递送的假体可以包括形成管状支架结构的多个互连的支柱。 支柱包括通孔（50），其内表面构造成保持生物可吸收储库。 生物可吸收贮库包括在植入时水解降解的药物 - 聚合物组合物。 通孔的内表面可以是一个完全平滑和连续的凹或凸的区域，没有几何不连续。 通孔的内表面可以包括任何数量的收缩和扩张的区域，以形成仔细选择以接合生物可吸收贮库的相应几何特征的尺寸和形状的凹槽。

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