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公开(公告)号：WO2020263812A1
公开(公告)日：2020-12-30
申请号：PCT/US2020/039112
申请日：2020-06-23
Applicant: AUBURN UNIVERSITY , BAYER CROPSCIENCE LP
Inventor： KLOEPPER, Joseph W. , MCINROY, John A. , ALLY, Dilara , BERNHARD, Joshua , FERNANDEZ, Lorena , GUILHABERT, Magalie , NANGLE, Kate W. , THOMAS, Varghese P. , MANAVALAN, Lakshmi Praba
Abstract: The present invention relates to a composition comprising a biologically pure culture of Bacillus spp . strain NRRL B-67746 and mutants of that strain having all the identifying characteristics of the strain. The present invention also provides a method of promoting plant growth, wherein the method comprises applying such strain or mutants to the plant, to a part of the plant and/or to a locus of the plant.
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公开(公告)号：WO2022241209A1
公开(公告)日：2022-11-17
申请号：PCT/US2022/029179
申请日：2022-05-13
Applicant: BAYER CROPSCIENCE LP
Inventor： VALENCIA-MORALES, Edgar , THOMAS, Varghese P.
IPC: C12Q1/689
Abstract: Compositions and methods for identifying and/or quantifying one or more bacterial and/or fungal strain(s) are described. An example composition includes a biosample, and one or more combination(s) of a forward primer sequence, a reverse primer sequence, and a probe sequence. Each of the one or more combination(s) is specific for a single bacterial strain or a single fungal strain. The composition may be used to identify and/or quantify the bacterial strain or fungal strain when present, or identified, in the biosample.
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公开(公告)号：WO2020190998A1
公开(公告)日：2020-09-24
申请号：PCT/US2020/023260
申请日：2020-03-18
Applicant: BAYER CROPSCIENCE LP , SPOGEN BIOTECH INC.
Inventor： AUGUSTIN, Jörg , CURTIS, Damian , HENRY, Elizabeth M. , HOTTON, Sara K. , LAMSA, Anne , MANAVALAN, Lakshmi Praba , THOMAS, Varghese P. , THOMPSON, Brian
Abstract: The present invention relates to a fusion protein having a targeting sequence, exosporium protein, or exosporium protein fragment that targets the fusion protein to the exosporium of a recombinant Bacillus cereus family member and a pectinase enzyme, wherein the pectinase is a pectate lyase from Bacillus spp. having any of SEQ ID NOs: 213-217 and 222-226 or a polygalaturonase from Aspergillus niger or certain Bacillus species that can have any of SEQ ID NOs: 210-212, 218-221, and 227. The present invention also provides a recombinant Bacillus cereus family member that expresses such fusion protein and exosporium fragments derived from such recombinant Bacillus cereus family member. Methods of using such recombinant Bacillus cereus family members or exosporium fragments derived therefrom for plant growth promotion are also provided.
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公开(公告)号：WO2019140125A1
公开(公告)日：2019-07-18
申请号：PCT/US2019/013101
申请日：2019-01-10
Applicant: BAYER CROPSCIENCE LP
Inventor： THOMAS, Varghese P. , GOLOMB, Benjamin L. , CURTIS, Damian
CPC classification number: A61K36/48 , A01H3/00 , A01N63/00 , A01N63/02 , A01N65/20 , A61K2035/115 , C12N1/20 , C12N1/36
Abstract: The disclosure is generally directed to methods for screening, identifying, and producing microorganisms capable of imparting beneficial properties to plants. In some aspects, improved plant-associated soil microorganisms are generated by experimental evolution using a plant root exudate or root exudate compound.
