公开(公告)号：WO2015066521A1

公开(公告)日：2015-05-07

申请号：PCT/US2014/063518

申请日：2014-10-31

Applicant: C2 THERAPEUTICS, INC.

Inventor： NEWELL, Gabriel, Francis W. ,  HOLLAND, Timothy, Douglas ,  ICO, Cesar, A. ,  WU, Patrick, P. ,  WILLIAMS, Richard, S.

IPC: A61B18/02

CPC classification number: A61B18/02 ,  A61B2017/00398 ,  A61B2017/00477 ,  A61B2018/00041 ,  A61B2018/00202 ,  A61B2018/00208 ,  A61B2018/0022 ,  A61B2018/00482 ,  A61B2018/00488 ,  A61B2018/00494 ,  A61B2018/005 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00648 ,  A61B2018/00714 ,  A61B2018/00744 ,  A61B2018/00791 ,  A61B2018/00815 ,  A61B2018/00916 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61B2018/0268 ,  A61B2090/064 ,  A61B2576/02

Abstract: A cryogenic ablation catheter 12 includes a catheter shaft 16, a balloon 24 and a connector 30 respectively at the catheter shaft proximal and distal ends 18, 20, a refrigerant delivery tube assembly including a refrigerant delivery tube 34 rotatable within the catheter shaft lumen 22, and a refrigerant delivery element 40 with an outlet 42 located inside the balloon which directs refrigerant 44 outwardly against the balloon at different rotary positions as it rotates. A cryogenic balloon ablation system 10 includes the cryogenic ablation catheter, a catheter coupler 119 mating with the connector, a motor 104 including a rotatable hollow motor shaft 102, and a delivery line 100 fluidly coupled to a cryogenic gas source 84 for supplying cryogenic gas to the refrigerant delivery tube. At least one of the refrigerant delivery tube and the delivery line passes at least partway through the hollow motor shaft. The coupling tip 60 of the connector and the refrigerant delivery tube 34 rotate with the motor shaft 102.

Abstract translation: 低温消融导管12包括分别位于导管轴近侧和远端18,20处的导管轴16，球囊24和连接器30，包括可在导管轴腔22内旋转的制冷剂输送管34的制冷剂输送管组件， 以及具有位于球囊内部的出口42的制冷剂输送元件40，其在致动器旋转时在不同的旋转位置向外引导制冷剂44抵靠气球。 低温球囊消融系统10包括低温消融导管，与连接器配合的导管联接器119，包括可旋转的中空电机轴102的电动机104以及与低温气体源84流体耦合以将低温气体供应到 制冷剂输送管。 制冷剂输送管和输送管中的至少一个至少一部分通过中空的电动机轴。 连接器的联接尖端60和制冷剂输送管34与电动机轴102一起旋转。