公开(公告)号：WO2014152091A3

公开(公告)日：2014-11-27

申请号：PCT/US2014026939

申请日：2014-03-14

Applicant: CARNEGIE INST OF WASHINGTON

Inventor： ZHENG YIXIAN ,  JIA JUNLING ,  ZHENG XIAOBIN

IPC: C12Q1/68 ,  C12P21/06

CPC classification number: C12Q1/6806 ,  C12Q2535/113 ,  C12Q2563/149

Abstract: Novel methods of ChlP-seq are disclosed herein. These methods of ChlP-seq employ carrier DNA to prevent loss of DNA samples. The greater DNA yields achieved by this invention permit ChlP-seq of a small number of cells, permitting epigenetic analysis of primary cells of limited quantity.

Abstract translation: 本文公开了ChlP-seq的新方法。 ChlP-seq的这些方法使用载体DNA来防止DNA样品的损失。 通过本发明实现的更大的DNA产量允许少量细胞的ChlP-seq，允许有限量的原代细胞的表观遗传分析。