公开(公告)号：WO2022251494A1

公开(公告)日：2022-12-01

申请号：PCT/US2022/031128

申请日：2022-05-26

Applicant: DIALITY INC.

Inventor： BORILLO, Brandon ,  CHEN, Tzu, Tung

IPC: A61M1/14 ,  A61M1/36 ,  B01J20/02 ,  C12N9/14

Abstract: Sorbent regeneration systems for use in dialysis machines are described. Sorbent regeneration cartridges may include a layer of urease, a layer of acid zirconium phosphate, and a layer of sodium zirconium phosphate. An apparatus for conducting dialysis may include a sorbent cartridge, and a dialyzer in fluid communication with the sorbent cartridge, wherein spent dialysate passes from the dialyzer to and through the sorbent cartridge, and wherein the sorbent cartridge comprises a layer of urease, a layer of acid zirconium phosphate, and a layer of sodium zirconium phosphate. The urease may be immobilized to or associated with a carrier.