PREPARATION OF 'alpha'-TOCOPHEROL
    3.
    发明申请
    PREPARATION OF 'alpha'-TOCOPHEROL 审中-公开
    阿托伐他汀的制备

    公开(公告)号:WO1997007113A1

    公开(公告)日:1997-02-27

    申请号:PCT/US1996013343

    申请日:1996-08-14

    CPC classification number: C07D311/72 Y02P20/582

    Abstract: Disclosed is an improved process for the preparation of alpha-tocopherol by the hydroxymethylation followed by the hydrogenation of non- alpha -tocopherols comprising beta -, gamma -, and delta -tocopherols using a particular palladium on alumina catalyst wherein (1) the dispersion and depth of deposition of the palladium metal are within certain ranges, and (2) the alumina is of a particular crystalline phase.

    Abstract translation: 公开了一种通过羟甲基化制备α-生育酚的改进方法,随后使用特定的氧化铝催化剂氢化包含β - ,γ - 和δ-生育酚的非α-生育酚,其中(1)分散体和 钯金属的沉积深度在一定范围内,(2)氧化铝具有特定的结晶相。

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