公开(公告)号：WO2018017574A1

公开(公告)日：2018-01-25

申请号：PCT/US2017/042605

申请日：2017-07-18

Applicant: PEPSICO, INC.

Inventor： ERICKSON, Shawn ,  FENG, Yu-Wen ,  GALOPIN, Christophe ,  GRAVINA, Stephen ,  KURASH, Yuliya ,  LEE, Thomas ,  NATTRESS, Laura ,  WANG, Ting

IPC: A23L27/30 ,  A23L2/60

Abstract: The present disclosure provides novel sweetener compositions comprising a compound having a structure according to Formula (I): wherein R1, R2, R3, and R4 are described herein. Also provided are methods of modulating sweetness profile of a product by adding a compound of Formula (I) to the product, such as a beverage product or a food product. For example, the compound described herein can be added to increase the overall sweetness of a nutritive sweetener sweetened beverages; decrease the sweetness time-ofonset for high potency sweeteners such as rebaudioside A; decreasing bitter, metallic and licorice off-notes of high potency sweeteners; and improve the sweet quality of sweetened products.

Abstract translation: 本公开提供了包含具有式（I）结构的化合物的新型甜味剂组合物：其中R 1，R 2，R 3和R 4如本文所述。 还提供了通过将式（I）化合物添加至产品如饮料产品或食品来调节产品的甜味特征的方法。 例如，可以加入本文所述的化合物以增加营养甜味剂增甜饮料的总体甜度; 降低高效甜味剂例如莱鲍迪甙A的甜味时间; 降低高效甜味剂的苦味，金属和甘草异味; 并改善甜味产品的甜味。

公开(公告)号：WO2015094729A1

公开(公告)日：2015-06-25

申请号：PCT/US2014/068996

申请日：2014-12-08

Applicant: PEPSICO, INC.

Inventor： AGLIONE, Anthony ,  CASSUTT, Kelly, J. ,  DRAGAN, Sofya ,  GRAVINA, Stephen ,  KURASH, Yuliya ,  JOHNSON, Winsome

IPC: A23L1/236

CPC classification number: A23L2/60 ,  A23L2/52 ,  A23L2/56 ,  A23L3/3463 ,  A23V2002/00

Abstract: A beverage comprising water, at least one non-nutritive sweetener having a bitter off-note taste, linoleic acid, and heptanoic acid. A beverage comprising water, at least one non-nutritive sweetener, a combination of caprylic acid, caproic acid, and butyric acid, and at least one aldehyde selected from the group consisting of decanal, nonanal, and 2-methyl-butyraldehyde.

Abstract translation: 一种饮料，其包含水，至少一种具有苦味淡味味的非营养甜味剂，亚油酸和庚酸。 一种饮料，其包含水，至少一种非营养甜味剂，辛酸，己酸和丁酸的组合以及至少一种选自癸醛，壬醛和2-甲基 - 丁醛的醛。

公开(公告)号：WO2014183044A1

公开(公告)日：2014-11-13

申请号：PCT/US2014/037511

申请日：2014-05-09

Applicant: PEPSICO, INC.

Inventor： KURASH, Yuliya ,  GRAVINA, Stephen

IPC: C07K14/075

CPC classification number: G01N33/5041 ,  C07K14/43504 ,  C07K14/47 ,  C07K14/705 ,  G01N33/5044 ,  G01N33/74 ,  G01N2333/726 ,  G01N2333/912 ,  G01N2440/14

Abstract: Co-expression of T1R2 and T1R3 results in a taste receptor that responds to sweet taste stimuli, including naturally occurring and artificial sweeteners. Cells such as U2-OS, which express a functional sweet receptor, can be used in cell-based assays to detect cellular responses to tastants.

Abstract translation: T1R2和T1R3的共表达导致对甜味刺激（包括天然存在的和人造甜味剂）起反应的味觉受体。 表达功能性甜味受体的诸如U2-OS的细胞可用于基于细胞的测定以检测对促味剂的细胞反应。

公开(公告)号：WO2014183041A1

公开(公告)日：2014-11-13

申请号：PCT/US2014/037507

申请日：2014-05-09

Applicant: PEPSICO, INC.

Inventor： KURASH, Yuliya ,  GRAVINA, Stephen

IPC: C07K14/705

CPC classification number: G01N33/566 ,  C07K14/705 ,  G01N2500/10

Abstract: This disclosure provides a taste receptor internalization assay useful for identifying taste modulators.

Abstract translation: 本公开提供了可用于鉴定味觉调节剂的味觉受体内化测定。