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公开(公告)号：WO2019145733A1
公开(公告)日：2019-08-01
申请号：PCT/GB2019/050219
申请日：2019-01-25
Applicant: UCL BUSINESS PLC , IMPERIAL INNOVATIONS LIMITED
Inventor： BRETT, Daniel , BROWN, Leon , MASON, Thomas , DEDIGAMA, Ishanka , KUCERNAK, Anthony
IPC: H01M8/18 , H01M2/16 , H01M4/96 , H01M8/0228
CPC classification number: H01M8/18 , H01M2/16 , H01M4/96 , H01M8/0228
Abstract: Herein is disclosed, a rechargeable flow battery, wherein the flow battery comprises: first and second electrodes, separated such that ions are allowed to flow between them, wherein a first reservoir comprising or for holding a first fluid electrolyte is fluidly connected to the first electrode, to allow circulation of the first fluid electrolyte from the first reservoir to the first electrode and from the first electrode to the first reservoir; and a first current collector comprising a layer of electrically conductive material having opposing first and second sides, wherein the first electrode is disposed on the first side of the first current collector, such that electrons can flow from the electrode to the first current collector, and a first layer of dielectric material is disposed on the second side of the first current collector.
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公开(公告)号：WO2019116024A1
公开(公告)日：2019-06-20
申请号：PCT/GB2018/053594
申请日：2018-12-11
Applicant: IMPERIAL INNOVATIONS LIMITED
Inventor： ELSON, Daniel Stuart , JANATKA, Miroslav , TATLA, Taranjit Singh , SINGH, Arvind , RAMDOO, Savram Krishan
Abstract: An ear examination tool comprises a handle and a speculum mount coupled to the handle. The speculum mount is configured for retaining a disposable speculum. An spacing element is coupled to the handle and extends from the handle. A smartphone mount is coupled to the spacing element, and the spacing element is configured to maintain an optical separation distance between the speculum mount and the smartphone mount. The tool enables a clear view of the ear canal while allowing access by, and manipulation of, a microsuction tool being inserted into the ear canal. The extensive optical and data processing functionality of a "smartphone" can be integrated at low cost into an ear examination tool to provide a substantially improved piece of equipment for assisting in ear examination and microsuction of the ear.
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公开(公告)号：WO2019102221A1
公开(公告)日：2019-05-31
申请号：PCT/GB2018/053407
申请日：2018-11-26
Applicant: IMPERIAL INNOVATIONS LIMITED
Inventor： HANNA, George , BOSHIER, Piers , BELLUOMO, Ilaria
IPC: G01N33/574 , G01N33/497
CPC classification number: G01N33/57446 , G01N33/497 , G01N33/57488 , G01N2033/4975 , G01N2033/4977 , G01N2333/245 , G01N2333/26 , G01N2333/315 , G01N2333/33 , G01N2333/335
Abstract: The invention relates to the detection of biomarkers, and methods, compositions and kits for the detection of such biological markers for diagnosing various conditions, such as cancer. In particular, the invention relates to the detection of compounds as diagnostic and prognostic markers for detecting cancer, such as oesophago-gastric cancer.
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公开(公告)号：WO2019038556A1
公开(公告)日：2019-02-28
申请号：PCT/GB2018/052404
申请日：2018-08-23
Applicant: IMPERIAL INNOVATIONS LIMITED
Inventor： WANG, Li-Liang , ELFAKIR, Omer , SUN, Yuhao , JI, Kang , LUAN, Xi , CAI, Zhaoheng , LIU, Xiaochuan
IPC: C21D8/00 , B21D22/02 , C21D9/46 , C21D9/48 , C21D1/34 , C22F1/04 , C22F1/06 , C22F1/18 , C21D1/673
Abstract: A method of forming a part from sheet metal and a part formed by said method are disclosed, the method comprising the steps of: (a) heating a metal sheet to a temperature T; and (b) forming the sheet into the part between dies whilst applying cooling means to the sheet, where in step a) the metal sheet is heated at a rate of at least 50 °C.s -1 , and temperature T is above a critical forming temperature and does not exceed a critical microstructure change temperature of said metal sheet.
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公开(公告)号：WO2019025784A1
公开(公告)日：2019-02-07
申请号：PCT/GB2018/052182
申请日：2018-07-31
Applicant: IMPERIAL INNOVATIONS LIMITED
Inventor： STAFFORD, Jason , MATAR, Omar , PETIT, Camille
IPC: C01B32/19 , B01J19/18 , C01B21/064
Abstract: The invention provides an apparatus for fluidic exfoliation of a layered material comprising: a housing of circular cross-section defined by a housing wall; a hollow rotor of circular cross-section having a first end and a second end and a wall positioned therebetween arranged concentrically within the housing, wherein the wall of the hollow rotor defines an inner chamber and the space between the wall of the hollow rotor and the housing wall defines an outer chamber, and wherein a fluid flow path is provided between the inner chamber and the outer chamber; a fluid inlet in fluid communication with the inner chamber or the outer chamber; and a fluid outlet in fluid communication with the other of the inner chamber or the outer chamber; wherein the outer chamber has a width such that on passage of a fluid comprising the layered material from the inlet to the outlet through the outer chamber, a shear rate sufficient to exfoliate the layered material may be applied to the fluid comprising the layered material in the outer chamber by rotation of the hollow rotor.
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Patent Agency Ranking
公开(公告)号：WO2019021002A1
公开(公告)日：2019-01-31
申请号：PCT/GB2018/052106
申请日：2018-07-26
Applicant: IMPERIAL INNOVATIONS LIMITED , UCL BUSINESS PLC
Inventor： BREEZE, Jonathan , ALFORD, Neil , KAY, Chris , SATHIAN, Juna , SALVADORI, Enrico
Abstract: Apparatus for achieving masing at room temperature, the apparatus comprising: a microwave cavity which exhibits a resonance of sufficiently high Q-factor for maser oscillation; a resonator structure comprising a masing medium located within a resonant element, wherein the masing medium comprises spin-defect centres, the resonator structure being disposed within the microwave cavity; means for applying a magnetic field across the masing medium; an input of microwave radiation to be amplified, the input of microwave radiation being coupled to the resonator structure; and means for optically pumping the masing medium and thereby causing stimulated emission of microwave photons; wherein the microwave cavity has an effective magnetic mode volume matching the volume of the masing medium. A corresponding method for producing masing at room temperature is also provided.
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公开(公告)号：WO2019008380A1
公开(公告)日：2019-01-10
申请号：PCT/GB2018/051917
申请日：2018-07-05
Applicant: IMPERIAL INNOVATIONS LIMITED
Inventor： COOK, Marcus , LIVINGSTON, Andrew Guy
Abstract: Processes for the preparation of composite membranes are disclosed, as well as the composite membranes obtainable by these processes. The processes employ a step of roller coating a porous support substrate with an essentially solventless coating mixture containing a cationically UV curable compound, which can then be cured in an oxygen-containing atmosphere. The process thereby dispenses with–or greatly reduces the impact of–a number of the prominent processing constraints of prior art techniques, thereby affording a more streamlined and less energetically burdensome membrane manufacturing process.
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公开(公告)号：WO2018206960A1
公开(公告)日：2018-11-15
申请号：PCT/GB2018/051260
申请日：2018-05-10
Applicant: IMPERIAL INNOVATIONS LIMITED
Inventor： ZHOU, Wenbin , LIN, Jianguo , DEAN, Trevor , WANG, Liliang
Abstract: A method of extruding a material, comprising providing the material into an extrusion chamber of an extrusion apparatus, wherein the extrusion chamber comprises an extrusion orifice and the extrusion apparatus comprises a first compression element and a second compression element in communication with the interior of the extrusion chamber, the first and second compression elements being independently movable relative to the extrusion chamber, moving at least one of the first and second compression elements to compress the material within the extrusion chamber and cause a velocity gradient in the extrusion material across the extrusion orifice and extruding the material through the extrusion orifice such that the velocity gradient forms an extrudate with a curved profile.
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公开(公告)号：WO2018197865A1
公开(公告)日：2018-11-01
申请号：PCT/GB2018/051078
申请日：2018-04-25
Applicant: IMPERIAL INNOVATIONS LIMITED
Inventor： KANAGARATNAM, Prapa , LINTON, Nick , FRANCIS, Darrel
IPC: A61B5/042 , A61B5/046 , A61B5/0464
Abstract: Apparatus for monitoring activation in a heart comprises a probe (101), a plurality of electrodes (102) supported on the probe and extending over a detection area of the probe, the detection area being arranged to contact a detection region of the heart. Each of the electrodes (102) is arranged to detect electrical potential at a respective position in the heart during movement of a series of activation wave fronts across the detection region. A processor is arranged to analyse the detected electrical potentials to identify a propagation direction of at least one of the wave fronts, and to generate an output indicative of that direction.
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公开(公告)号：WO2018197859A1
公开(公告)日：2018-11-01
申请号：PCT/GB2018/051070
申请日：2018-04-24
Applicant: IMPERIAL INNOVATIONS LIMITED
Inventor： HAJITOU, Amin , SUWAN, Keittisak , ALBAHRANI, Mariam , WARAMIT, Sajee
IPC: C07K14/525 , C07K14/54 , C12N15/113 , C12N15/86 , C12N7/00 , C12N7/04 , A61K33/24 , A61K39/00 , A61K48/00
Abstract: The present invention provides phagemid vectors and associated phagemid particles for cancer treatment, and in particular, to the use of novel phagemid particles and associated expression systems for the treatment, prevention, amelioration, or management of cancer. In particular, the invention relates to the use of phagemid particles and expression systems for the delivery of transgenes encoding cytokines, for the treatment, prevention, amelioration, or management of cancer. The invention also extends to the use of phagemid particles and expression systems for the delivery of transgenes, and for the combination of such treatment with the use of adoptively transferred T cells, for the treatment, prevention, amelioration, or management of cancer.
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