US07723748B2
A SGPMOS transistor includes a base, a P-type diffusion layer, a gate electrode, and a LOCOS oxide film. The base includes at least one of a N-type semiconductor substrate, a P-type semiconductor substrate, and a N-type well. The P-type diffusion layer includes a P-type source and a P-type drain. At least the P-type drain includes a double diffusion structure including first and second P-type drain diffusion layers. The LOCOS oxide film is provided on the first P-type drain diffusion layer and covered by an end of the gate electrode. The first and the second P-type drain diffusion layers satisfy a relation of Y
US07723746B2
A polarized light emitting diode (LED) includes a marker indicating a polarization direction. A package for the LED also includes a marker indicating the polarization direction. The markers on the LED and package are used for mutual alignment, wherein the LED is attached in a favorable orientation with respect to a package, so that the polarization direction of emitted light from the package is apparent. The marker is placed on the LED before die separation and the marker is placed on the package before alignment. The marker on the LED comprises a photolithographic pattern, an asymmetric die shape, a notch on the die, or a scratch on the die, while the marker on the package comprises an electrode shape or pattern, an asymmetric package shape, a notch on the package, or a scratch on the package. Finally, the LED or package may be installed in an external circuit or system that also indicates the polarization direction.
US07723744B2
Light-emitting devices are provided that incorporate one or more underlying LED chips or other light sources and a layer having one or more populations of nanoparticles disposed over the light source. The nanoparticles may absorb some light emitted by the underlying source, and re-emit light at a different level. By varying the type and relative concentration of nanoparticles, different emission spectra may be achieved. White light and specialty-color emission may be achieved. Devices also may include multiple LED chips, with nanoparticles disposed over one or more underlying chips in an array.
US07723722B2
Objects of the present invention are to provide novel anthracene derivatives and novel organic compounds; a light-emitting element that has high emission efficiency; a light-emitting element that is capable of emitting blue light with high luminous efficiency; a light-emitting element that is capable of operation for a long time; and a light-emitting device and an electronic device that have lower power consumption. An anthracene derivative represented by a general formula (1) and an organic compound represented by a general formula (17) are provided. A light-emitting element that has high emission efficiency can be obtained by use of the anthracene derivative represented by the general formula (1). Further, a light-emitting element that has a long life can be obtained by use of the anthracene derivative represented by the general formula (1).
US07723718B1
Techniques for fabricating metal devices, such as vertical light-emitting diode (VLED) devices, power devices, laser diodes, and vertical cavity surface emitting laser devices, are provided. Devices produced accordingly may benefit from greater yields and enhanced performance over conventional metal devices, such as higher brightness of the light-emitting diode and increased thermal conductivity. Moreover, the invention discloses techniques in the fabrication arts that are applicable to GaN-based electronic devices in cases where there is a high heat dissipation rate of the metal devices that have an original non- (or low) thermally conductive and/or non- (or low) electrically conductive carrier substrate that has been removed.
US07723714B2
A memory cell (10) comprising at least a source electrode (MS) formed on a substrate (6); at least a drain electrode (MD) formed on the substrate (6); at least a coupling layer (1) formed between the source electrode (MS) and the drain electrode (MD), and at least a gate electrode (MG) formed on the substrate (6), wherein the coupling layer (1) comprises a transition-metal oxide exhibiting a filling-controlled metal-insulator transition property; the gate electrode (MG) comprises an oxygen ion conductor layer (2), and the gate electrode (MG) is arranged relative to the coupling layer (1) such that application of an electrical signal to the gate electrode (MG) causes alteration of the oxygen vacancy (3) concentration in the coupling layer (1).
US07723712B2
Memory cells for reduced power consumption and methods for forming the same are provided. A memory cell has a layer of phase change material. A first portion of the phase change material layer includes the programmable volume of the memory cell and its crystalline state has a higher resistivity than that of the crystalline state of a second portion of the phase change material layer.
US07723705B2
Techniques for measuring ion beam emittance are disclosed. In one particular exemplary embodiment, the techniques may be realized as an apparatus for measuring ion beam emittance. The apparatus may comprise a measurement assembly comprising a first mask, a second mask, and a pivot axis, such that the measurement assembly rotates about the pivot axis in order to scan an ion beam using either the first mask or the second mask to measure ion beam emittance for providing a measure of ion beam uniformity.
US07723704B2
According to one exemplary embodiment, an extreme ultraviolet (EUV) pellicle for protecting a lithographic mask includes an aerogel film. The pellicle further includes a frame for mounting the aerogel film over the lithographic mask. The aerogel film causes the pellicle to have increased EUV light transmittance.
US07723699B2
A cathode having electron production and focusing grooves for an ion source of an ion implanter system, the ion source and a related method are disclosed. In one embodiment, the cathode includes a working surface having a plurality of electron production and focusing grooves positioned therein. A repeller of the ion source may be similarly structured.
US07723698B2
When using micro-resonant structures which are being excited and caused to resonate by use of a charged particle beam, whether as emitters or receivers, especially in a chip or circuit board environment, it is important to prevent the charged particle beam from coupling to or affecting other structures or layers in the chip or circuit board. Shielding can be provided along the path of the charged particle beam, on top of the substrate, to prevent such coupling.
US07723695B2
This imaging apparatus has pixels arranged in a matrix shape on a substrate, each of which has a conversion element and the first TFT, wherein the first TFT is connected to the first gate wiring and signal wiring, and the conversion element is connected to bias wiring. The imaging apparatus has the second TFT 6 that is arranged outside a region in which the pixels are arranged. The signal wirings are mutually connected through the second TFT 6 outside a region in which the pixels are arranged. When the apparatus is driven, the second TFT is turned off.
US07723694B2
A radiation detector includes an array of detector pixels each including an array of detector cells. Each detector cell includes a photodiode biased in a breakdown region and digital circuitry coupled with the photodiode and configured to output a first digital value in a quiescent state and a second digital value responsive to photon detection by the photodiode. Digital triggering circuitry is configured to output a trigger signal indicative of a start of an integration time period responsive to a selected number of one or more of the detector cells tranisitioning from the first digital value to the second digital value. Readout digital circuitry accumulates a count of a number of transitions of detector cells of the array of detector cells from the first digital state to the second digital state over the integration time period.
US07723691B2
In a method of manufacturing a radiation detector according to this invention, a lattice frame 40 is stored in a receptacle 50, and scintillators 1SF and 1SR are also stored therein. The lattice frame 40 and scintillators 1SF and 1SR are once taken out of the receptacle in a state of trial assembly as a two-stage scintillator block in trial assembly 54. The lattice frame 40 and scintillators 1SF and 1SR in trial assembly are stored in the receptacle 50 into which an optical binding material has been poured. This method can reduce trouble occurring in manufacture to realize a radiation detector simply.
US07723689B2
A radiographic three dimensional imaging apparatus capable of focusing on a center of rotation point, includes at least two gamma ray detectors, each having a radiation input face, with each detector positioned on a linear path, wherein each detector is movable along the detector's linear path, while simultaneously swiveling to maintain the detector's input face towards the rotation point. The apparatus allows for organ-targeted tomography as a virtual center of rotation can be placed arbitrarily with respect to a patient, constrained only by the physical limits of the detector motion.
US07723688B2
Methods and systems for imaging a subject using an imaging system are provided. The method includes rotating a first detector and a second detector about a subject and determining a distance of the first detector and the second detector from the subject. The method further includes automatically adjusting the position of at least one of the first detector and the second detector to within a predetermined distance range if the determined distance of one of the first and second detectors is not within the predetermined distance range.
US07723679B2
A coaxial hybrid ion trap that uses two substantially planar opposing plates to generate electrical focusing fields that simultaneously generate at least two different types or shapes of trapping regions, wherein a first trapping region is a quadrupole trapping region disposed coaxially with respect to the opposing plates, and wherein a second trapping region is a toroidal ion trap having a toroidal trapping region that is simultaneously created around the quadrupole trapping region.
US07723678B2
An apparatus and method for generating analyte ions from a sample. An ion generating device is provided having a chamber with an outlet and a surface having a material and means for applying a high velocity gas flow through the chamber toward the outlet such that charged particles are produced by physical interaction between the high velocity gas and the material. The charged particles then induce the generation of primary ions by interaction with molecules of the high velocity gas. The primary ions are emitted from the outlet of the ion generating device toward a sample-bearing surface and analyte ions are generated by impact of the primary ions on the analyte sample on the surface.
US07723669B2
There is provided an optical movement sensing system which can be miniaturized and ensures a wide angle of view. The optical movement sensing system collecting light reflected from an object to be imaged on an optical sensor, the optical movement sensing system including: a wide-angle lens including a first lens element having a curved object-side surface; and a second lens element having an object-side surface in contact with an image-side surface of the first lens element and having a planar image-side surface. The optical movement sensing system with this configuration can be reduced in size and weight and has a wide angle of view. Therefore, the optical movement sensing system is applicable to a mobile device such as a mobile telecommunication terminal and assures sufficient peripheral light amount.
US07723666B2
Provided is a photodiode array that is capable of outputting an electric signal with a large electric power and an optical microwave transmission system receiver that supplies an electric power with the aid of an optical fiber and does not require the electric power line from the external. An input modulation light is branched and input to a plurality of photodiode elements (1), electric output terminals (5) of the plurality of photodiode elements (1) are connected in parallel to each other, and a combined electric output is extracted. The electric output terminal (5) of the photodiode array configured as described above is connected to an antenna (7) without an intermediation of an amplifier circuit.
US07723662B2
Light-field microscopy is facilitated using an approach to image computation. In connection with an example embodiment, a subject (e.g., 105) is imaged by passing light from the subject through a microlens array (e.g., 120) to a photosensor array (e.g., 130) to simultaneously detect light from the subject that is passed through different directions to different locations. In certain embodiments, information from the detected light is used to compute refocused images, perspective images and/or volumetric datasets, from a single-shot photograph.
US07723658B2
A solar sensor is provided that has microspheres on an interior face of a protective cap or of another radiation-transparent area above a transducer of the sensor. The microspheres scatter the light but at the same time have a much lower damping effect. Preferably, the microspheres are glued to or sealed into the interior face.
US07723656B1
A microwavable food package is disclosed, comprising a packaging sheet including first and second column of apertures, the apertures between 100 microns and 800 microns in diameter; and a central seal, the central seal joining a first edge of the packaging sheet to a second edge of the packaging sheet, the central seal running longitudinally along the length of the food package, wherein the first column of apertures is on one side of the central seal and the second column of apertures is on the other side of the central seal.
US07723654B2
An apparatus and method for on-site microwave consolidation of planetary regolith, soil and dust is disclosed. Such particulate materials may be converted into useful products such as roadways and other construction materials. In one embodiment, a portable microwave generator and waveguide system is used to generate and direct microwaves to a lunar surface containing fine iron-containing particles to sinter and/or melt the particles. The portable system may be provided in the form of a lunar paver with a single or multiple waveguides arranged to direct sufficient microwave energy to the lunar surface to heat, sinter, melt, or otherwise consolidate the lunar soil into a solid mass suitable for use as a road or path. Other applications of this in-situ microwave heating process include the release of solar-wind implanted gases, extraction of polar water-ice, and production of oxygen.
US07723648B2
A substrate holder for supporting a substrate in a processing system includes a temperature controlled support base having a first temperature, and a substrate support opposing the temperature controlled support base and configured to support the substrate. Also included is one or more heating elements coupled to the substrate support and configured to heat the substrate support to a second temperature above the first temperature, and a thermal insulator disposed between the temperature controlled support base and the substrate support. The thermal insulator includes a non-uniform spatial variation of the heat transfer coefficient (W/m2-K) through the thermal insulator between the temperature controlled support base and the substrate support.
US07723632B2
An electrical switch has two fixed contacts and a moving contact, a spring urging the moving contact towards contacting the fixed contacts, and an actuating mechanism for moving the moving contact away from the fixed contacts against urging by the spring and, alternatively, allowing the moving contact to contact the fixed contacts under the action of the spring. The actuating mechanism has an engaging member for engaging and retaining the moving contact and includes a spring acting on the engaging member for separating the moving contact from the fixed contacts through an instant spring-release action. One of the engaging member and the contacts is configured such that the moving contact will be engaged and moved by the engaging member out of contact with one of the fixed contacts earlier than with the other fixed contact.
US07723629B2
An actuator assembly and packaging feature for an electric toothbrush is disclosed. The actuator assembly includes a positionable member accessible along the outer surface of the toothbrush body. The actuator assembly further includes a spring member retained within the interior of the toothbrush body which urges a cam member against the underside of the positionable member. The positionable member defines an aperture extending through its midsection within which is disposed a depressible member. The depressible member has an outer end which is also accessible along the outer surface of the toothbrush body. Upon pressing the depressible member, the cam member and spring are urged against an electrical circuit provided within the body of the toothbrush which is used to selectively operate a motor and drive mechanism to move one or more sets of bristles. The actuator assembly additionally includes a feature of providing a raised region along an outer surface of the positionable member which guards against accidental or unintentional depressing of the depressible member. The packaging feature relates to a member formed in a package cover that is suitably sized and positioned over the depressible member of the actuator so that the cover, when pressed, may momentarily activate the toothbrush within the package.
US07723624B2
An electronic apparatus is provided with a housing including a top wall and a side portion extending from an edge of the top wall, a keyboard, and a keyboard placing portion on which the keyboard is placed, the keyboard placing portion including a bottom surface provided in the top wall. At least part of the bottom surface extends to the side portion of the housing.
US07723619B2
Continuous annular resin bands surrounding electrical contact portions of respective terminals are disposed without gaps between the electrical contact portions of respective terminals and resin members that fixedly hold the terminals; there are formed gaps among the adjoining resin bands. Gaps are formed among a bundle of terminals having annular resin bands and resin members surrounding the bundle. A partial adhesion is formed at the interface between the terminals and the resin by a low cost manufacturing method, whereby a molding with high air-tightness between the interior and exterior thereof and high reliability is realized.
US07723617B2
A wired circuit board has a metal supporting board, a metal foil formed on the metal supporting board to have a thickness of less than 2.0 μm, a first insulating layer formed on the metal supporting board to cover the metal foil, and a conductive pattern formed on the first insulating layer.
US07723615B2
A fluororesin composition including a tetrafluoroethylene/hexafluoropropylene-based copolymer and 0.01 to 3 parts by mass per 100 parts the copolymer of a polytetrafluoroethylene having a standard specific gravity of 2.15 to 2.30, and being obtained by mixing an aqueous dispersion of the tetrafluoroethylene/hexafluoropropylene-based copolymer with an aqueous dispersion of the polytetrafluoroethylene, causing coagulation, drying the polymer mixture and melt-extruding the same.
US07723598B2
An electronic proof system is provided in association with an automatic player piano; while a human player is practicing a music tune on the acoustic piano, the electronic proof system monitors the pedals of piano to see whether or not the player brings the pedals to target pedal positions; if the current pedal position is spaced from the target pedal position, the electronic proof system gives rise to fine vibrations of the pedal, and makes the player notice the pedal staying at incorrect pedal position through the tactile impression.
US07723597B1
An improved 3-dimensional musical keyboard apparatus comprises a plurality of planar, longitudinally extending keys mounted for both downward depression and longitudinal displacement; spring components to return an unguided key to its at-rest position; means to limit the extent of key motion; sensing means to detect key position at any point in its range of motion; and electronic digital signal processor means responsive to key position signals and productive of musical control information. Additionally, it comprises a single line of contact structure for restraining keys from lateral motion; differential damping for the vertical and horizontal components of key motion; simplified means for signaling key center position in the displacement axis; and support for musical articulation in the direction of key displacement when a key is moving upward from a depressed position.
US07723593B1
This invention is a reversible practice pad for drum practice. The reversible practice pad includes a planar base having at least one sloping base-riser projecting upwardly therefrom. Each base-riser includes a first part of a two-part fastening material affixed to a top surface of each base-riser. A planar platform includes at least one sloping platform-riser projecting downwardly therefrom. Each platform-riser includes a second part of the two-part fastening material affixed to a bottom surface of each platform-riser. The platform includes a cushioning pad fixed to a top surface thereof. The bottom surface of each platform-riser is brought into contact and fastened with the top surface of an associated base-riser. The base and platform can be selectively fixed together in two different orientations by rotating the platform. In one orientation, the platform and the base are substantially parallel. In an alternate orientation, the platform is sloped with respect to the base.
US07723591B1
A wind instrument stand has an upper pivot slide, a lower pivot bracket, multiple legs, multiple links and a post assembly. The legs are connected pivotally to the upper pivot slide. Each link is connected pivotally between the lower pivot bracket a corresponding leg. The post is mounted slidably through the upper pivot slide and securely on the lower pivot bracket. The wind instrument stand may be folded into a compact configuration and be inserted into an opening of a wind instrument to facilitate the storage and carrying of the wind instrument and stand.
US07723589B1
According to the invention, there is provided seed and plants of the corn variety designated CV688430. The invention thus relates to the plants, seeds and tissue cultures of the variety CV688430, and to methods for producing a corn plant produced by crossing a corn plant of variety CV688430 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV688430 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV688430.
US07723585B2
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH261787. The invention thus relates to the plants, seeds and tissue cultures of the variety CH261787, and to methods for producing a corn plant produced by crossing a corn plant of variety CH261787 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH261787.
US07723574B2
A process for the production of Δ5-unsaturated fatty acids in transgenic organisms comprises transforming an organism with nucleic acid encoding a Δ5-desaturase.
US07723571B2
The present invention provides a method of using cereal non-storage protein as fusion carrier to highly express small peptides in host endosperm cells. The method includes the steps of providing an endosperm-specific promoter and a DNA leading sequence encoding an endosperm-specific signal peptide; providing the gene of a non-storage protein as fusion carrier and an target gene; constructing a expression vector containing the promoter and DNA leading sequence, the gene of the fusion carrier, and a target gene; and expressing the expression vector in a host endosperm cell. Also provided in the invention are a vector constructed there from and the use thereof.
US07723566B2
The invention relates to the filed of regeneration of cells, self-renewal of (micro-organisms), and the vegetative propagation of plant parts such as plant tissues or organs.
US07723546B1
Provided are arylamine compounds having Formula I, II, III, or IV: wherein Ar is the same or different at each occurrence and is aryl having from 6 to 30 carbon atoms or heteroaryl having from 2 to 30 carbon atoms. Also provided are compositions comprising arylamine compounds. The invention also relates to use of such compounds in electronic devices, for example, organic electronic devices.
US07723543B2
The invention relates to a method for the continuous production of alkyl amino acryl amides by reacting alkyl acrylates with high-boiling amines. A specific preparation technique is used in order to achieve hitherto unobtainable product qualities. Very high spatial, temporal and overall yields can also be obtained.
US07723530B2
The present invention relates to the use of polymerisable diketopyrrolopyrroles in colour filters, which can themselves be used for example in electro-optical systems such as TV screens, liquid crystal displays, charge coupled devices, plasma displays or electroluminescent displays and the like.In contrast to conventional pigments the polymerisable diketopyrrolopyrroles do not tend to aggregate and, hence, show very good dispersibility. Color filters prepared by using the polymerisable diketopyrrolopyrroles have high transparence and pure hue. In addition, they facilitate adjustment of color points and enable a large choice of shades.
US07723528B2
The use of N-formamidino-5-amino-3H-1,2,4-dithiazole-3-thiones as novel, efficient sulfur-transfer reagents is disclosed. The sulfur transfer from these reagents to compounds containing P(III) atom, triphenylphosphine, 5′-O-DMT-thymidine 2-cyanoethyl-(N,N-diisopropyl)phosphoramidite, and 5′-O-DMT-3′-O-levulinyl dithymidilyl 2-cyanoethyl phosphite, was studied in solution by 31P NMR and HPLC. The sulfur transfer from title compounds was also studied in the solid-phase synthesis of oligonucleotide phosphorothioates by phosphoramidite methods. In this application, the efficiency of the sulfur transfer reaction for 2′-deoxyoligonucleotides was better than 99.5%. The novel sulfurizing agents are synthesized, at low cost, using simple chemical methods. As opposed to many sulfur transfer reagents known in the prior art such as 1,2-benzodithiol-3-one-1,1-dioxide (Beaucage reagent) and 5-ethoxy-3H-1,2,4-dithiazole-2-one (EDIT), the sulfurizing agents disclosed herein are highly stable in solution, which increases their practical and commercial value.
US07723517B2
Disclosed are new dihydropteridinones of the formula (I) wherein the groups L, R1, R2, R3, R4 and R5 have the meanings provided herein, the isomers thereof, processes for preparing these dihydropteridinones and their use as pharmaceutical compositions.
US07723515B1
A methylene blue—curcumin hybrid useful in treating Alzheimer's Disease.
US07723513B2
The present invention provides dipyrrin substituted porphyrinic macrocycles, intermediates useful for making the same, and methods of making the same. Such compounds may be used for purposes including the making of molecular memory devices, solar cells and light harvesting arrays.
US07723495B2
To provide an amidite for nucleic acid synthesis, which enables a protective group therein to be removed under moderate conditions and can be practically used, and a nucleic acid synthesizing method using the amidite for nucleic acid synthesis. Specifically, the present invention relates to an amidite for nucleic acid synthesis represented by General Formula (I) below, and a nucleic acid synthesizing method using the amidite for nucleic acid synthesis: where X denotes a base; Y denotes a protective group formed of any one of a 4-aminobutyric acid derivative, an o-aminomethylbenzoic acid derivative, an o-aminophenylacetic acid derivative, an o-aminoethylbenzoic acid derivative, an o-aminomethylphenylacetic acid derivative, an o-aminophenylpropionic acid derivative and a 5-aminovaleric acid derivative; and Q denotes one of a hydrogen atom and a hydroxyl group.
US07723494B2
The present invention relates to novel yellow anionic dyes, a process for their preparation, certain novel intermediates necessary for their preparation and the use of these dyes for dyeing natural or synthetic materials, in particular, paper.
US07723493B2
Metal-containing complexes of a tridentate beta-ketoiminate, one embodiment of which is represented by the structure: wherein M is a metal such as calcium, strontium, barium, scandium, yttrium, lanthanum, titanium, zirconium, vanadium, tungsten, manganese, cobalt, iron, nickel, ruthenium, zinc, copper, palladium, platinum, iridium, rhenium, osmium; R1 is selected from the group consisting of alkyl, alkoxyalkyl, fluoroalkyl, cycloaliphatic, and aryl, having 1 to 10 carbon atoms; R2 is selected from the group consisting of hydrogen, alkyl, alkoxy, cycloaliphatic, and aryl; R3 is linear or branched selected from the group consisting of alkyl, alkoxyalkyl, fluoroalkyl, cycloaliphatic, and aryl; R4 is a branched alkylene bridge with at least one chiral center; R5-6 are individually linear or branched selected from the group consisting of alkyl, fluoroalkyl, cycloaliphatic, aryl, and can be connected to form a ring containing carbon, oxygen, or nitrogen atoms; n is an integer equal to the valence of the metal M.
US07723488B2
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
US07723485B2
Cysteine engineered anti-MUC16 antibodies are engineered by replacing one or more amino acids of a parent anti-MUC16 antibody with non cross-linked, reactive cysteine amino acids. Methods of design, preparation, screening, and selection of the cysteine engineered anti-MUC16 antibodies are provided. Cysteine engineered anti-MUC16 antibodies (Ab) are conjugated with one or more drug moieties (D) through a linker (L) to form cysteine engineered anti-MUC16 antibody-drug conjugates having Formula I: Ab-(L-D)p I where p is 1 to 4. Diagnostic and therapeutic uses for cysteine engineered antibody drug compounds and compositions are disclosed.
US07723481B2
The claimed invention relates to the discovery of a specific human taste receptor in the T2R taste receptor family, hT2R61 that responds to particular bitter compounds The present invention further relates to the use of this receptor in assays for identifying ligands that modulate the activation of this taste receptor. These compounds may be used as additives and/or removed from foods, beverages and medicinals in order to modify (block) T2R-associated bitter taste. A preferred embodiment is the use of the identified compounds as additives in foods, beverages and medicinals for blocking bitter taste.
US07723477B2
The present invention relates to compositions and methods for characterizing, diagnosing, and treating cancer. In particular the invention provides the means and methods for the diagnosis, characterization, prognosis and treatment of cancer and specifically targeting cancer stem cells. The present invention provides a soluble FZD receptor comprising an extracellular domain of a human FZD receptor that inhibits growth of tumor cells. The present invention still further provides a soluble receptor comprising a Fri domain of a human FZD receptor that binds a ligand of a human FZD receptor and said soluble receptor is capable of inhibiting tumor growth. The present invention still further provides a method of treating cancer comprising administering a soluble FZD receptor comprising for example, either an extracellular domain of a human FZD receptor or a Fri domain of a human FZD receptor, in an amount effective to inhibit tumor growth.
US07723472B2
The present invention provides chimeric polypeptides comprising a first polypeptide that binds to a component of extracellular matrix and a second polypeptide that provides for a therapeutic effect. The present invention further provides compositions, including pharmaceutical compositions, comprising a subject chimeric polypeptide. A subject chimeric polypeptide is useful in a variety of treatment, diagnostic, and research applications, which are also provided.
US07723471B2
The present invention provides novel Pancreatic Polypeptide Family (“PPF”) polypeptides and methods for their use.
US07723469B2
Novel polypeptides and methods of making and using the same are described herein. The polypeptides include cross-linking (“hydrocarbon stapling”) moieties to provide a tether between two amino acid moieties, which constrains the secondary structure of the polypeptide. The polypeptides described herein can be used to treat diseases characterized by excessive or inadequate cellular death.
US07723467B2
The invention features an antimicrobial composition comprising a substance P peptide and methods of inhibiting growth of a microorganism by contacting the microorganism with a substance P peptide. Bacterial and fungal pathogens are inhibited by the substance P compositions.
US07723464B2
Novel compositions of matter comprise certain derivatives of 9,9-dialkyl fluorene diamine (AFDA). The resultant compositions, whether compositions of matter or monomers that are subsequently incorporated into a polymer, are unique and useful in a variety of applications. Useful applications of AFDA-based material include heavy ion radiation shielding components and components of optical and electronic devices.
US07723463B2
Methods of removing contaminant matter from porous materials include applying a polymer material to a contaminated surface, irradiating the contaminated surface to cause redistribution of contaminant matter, and removing at least a portion of the polymer material from the surface. Systems for decontaminating a contaminated structure comprising porous material include a radiation device configured to emit electromagnetic radiation toward a surface of a structure, and at least one spray device configured to apply a capture material onto the surface of the structure. Polymer materials that can be used in such methods and systems include polyphosphazine-based polymer materials having polyphosphazine backbone segments and side chain groups that include selected functional groups. The selected functional groups may include iminos, oximes, carboxylates, sulfonates, β-diketones, phosphine sulfides, phosphates, phosphites, phosphonates, phosphinates, phosphine oxides, monothio phosphinic acids, and dithio phosphinic acids.
US07723462B2
The present invention relates generally to mercaptofunctional high μβ EO chromophores and EO polymers, and particularly to mercaptofunctional high μβ EO chromophores and EO polymers useful for making electro-optical devices and systems. Mercaptofunctional high μβ EO chromophores are covalently bonded to poly(imido sulfide) polymers producing high Tg, low optical loss, covalently bonded, high μβ EO chromophore containing polymers. Methods of synthesizing these EO materials using mild polymerization conditions are also described.
US07723461B1
Disclosed are polymers that include components produced from renewable resources and methods for forming the disclosed polymers. The polymers include the reactive intermediates that in turn include components derived from, for example, lactide or sorbitol. The reactive intermediates can be polymerized with each other as well as with more traditional resins to form polymeric networks. In one embodiment, the disclosed intermediates can be utilized in forming vinyl ester resins. In particular, the vinyl ester-styrene resins and thermoset networks formed therefrom including the disclosed intermediates can include lower styrene content than previously known vinyl ester-styrene resins, and can exhibit physical characteristics such as glass transition temperature and flexural strength properties equal to previously known vinyl ester-styrene resins that include a higher styrene content.
US07723455B2
The invention relates to conjugated polymers containing novel structural units according to formula (1). The inventive materials are characterized by increased efficiency and a longer service life when used in polymer organic light emitting diodes.
US07723454B2
A fiber of linear polymer coated with a siloxane-carborane polymer or a thermoset or ceramic made therefrom. An organic fiber coated with a siloxane-carborane polymer or a thermoset or ceramic made therefrom and a surfactant. An organic fiber coated with a siloxane-carborane polymer made from a hydrosilation reaction of a siloxane-carborane compound containing at least two unsaturated carbon-carbon bonds and a silane compound or a thermoset or ceramic made therefrom. A method of coating a fiber by contacting a fiber to an aqueous solution of a siloxane-carborane polymer and a surfactant or to a solution of a siloxane-carborane polymer in a non-halogenated organic solvent. A method of contacting a fiber to a solution of a siloxane-carborane polymer, drying the coating to a temperature that does not change the polymer to a thermoset or ceramic, and using the dried, coated fiber in a process that requires that the fiber be flexible.
US07723449B2
The present invention relates to a catalyst for synthesizing a polypropylene with a wide molecular weight distribution and use of the same. The catalyst comprises magnesium halide, titanium-containing compound, and an organic phosphate type electron donor compound. By the catalyst according to the present invention, a propylene polymer with a wide molecular weight distribution, easily controllable isotacticity and good processing properties can be synthesized.
US07723444B2
An epoxy resin composition which comprises an epoxy resin (A), a curing agent (B), a curing accelerator (C) and a component retarding curing of the epoxy resin (D) which is at least one component selected from components (a), (b) and (c) represented by general formulae [1], [2] and [3], respectively, a semiconductor device having a semiconductor element encapsulated by using the composition, and a process for providing latency to an epoxy resin composition. The epoxy resin exhibits excellent storage stability, excellent fluidity and curing property during encapsulating by molding and excellent resistance to soldering without forming cleavages or cracks by the soldering treatment at high temperatures in accordance with the lead-free soldering. An epoxy resin composition can be provided with latency by adjusting the amounts of the curing accelerator and the component for retarding curing. (a) An anion component represented by general formula [1]: (b) A compound represented by general formula [2]: (c) A silane compound represented by general formula [3]:
US07723440B2
A functionalized polymer defined by the formula π-R1-α, where π is a polymer chain, R1 is a bond or a divalent organic group, and α is a sulfur-containing heterocycle.
US07723413B2
Disclosed are a composition for controlling the crystallization rate of a polyolefin-based resin, the composition comprising (A) an amide-based compound which is a substituted or unsubstituted cyclohexylamide of 1,2,3-propanetricarboxylic acid or 1,2,3,4-butanetetracarboxylic acid and (B) a fatty acid metal salt, wherein the component (A):component (B) weight ratio is from 100:0 to 30:70; a method for controlling the crystallization rate of a polyolefin-based resin, comprising incorporating the composition into the polyolefin-based resin to obtain a polyolefin-based resin composition and molding the resin composition; molded products obtained by the method; and the like.
US07723406B2
A polymer-chain-grafted carbon nanocapsule. The polymer-chain-grafted carbon nanocapsule includes a carbon nanocapsule and at least one kind of polymer chain grafted thereon, forming a polymer-chain-grafted carbon nanocapsule in which the carbon nanocapsule is the core thereof. The polymer-chain-grafted carbon nanocapsules have the following formula: F(-P)m, in which F is the carbon nanocapsule, P is the polymer chain, and m is the number of the polymer chain. By grafting high-purity carbon nanocapsules with polymer chains, the application thereof is expanded.
US07723404B2
Coating compositions are disclosed that include an alkoxide and a silica sol that includes silica nanoparticles and a polymerizable (meth)acrylate binding agent. The polymerizable (meth)acrylate binding agent remains substantially uncrosslinked after the coating composition has been cured to form a hard coat. Also disclosed are articles at least partially coated with a hard coat deposited from such a coating composition, methods for depositing a hard coat on at least a portion of a plastic substrate, and methods for improving the adhesion and abrasion resistance of a coating composition.
US07723401B2
This invention relates to a process for making foundry shapes (e.g. cores and molds) using epoxy-acrylate cold-box binders containing an oxidizing agent and elevated levels of an organofunctional silane, which are cured in the presence of sulfur dioxide, and to a process for casting metals using the foundry shapes. The metal parts have fewer casting defects because the foundry shapes made with the binder are more resistant to erosion.
US07723394B2
The present invention is directed to a process for preparing a solid composite having colloidal nanocrystals dispersed within a sol-gel matrix, the process including admixing colloidal nanocrystals with an amphiphilic polymer including hydrophilic groups selected from the group consisting of —COOH, —OH, —SO3H, —NH2, and —PO3H2 within a solvent to form an alcohol-soluble colloidal nanocrystal-polymer complex, admixing the alcohol-soluble colloidal nanocrystal-polymer complex and a sol-gel precursor material, and, forming the solid composite from the admixture. The present invention is also directed to the resultant solid composites and to the alcohol-soluble colloidal nanocrystal-polymer complexes.
US07723392B2
A method of promoting or improving the feed efficiency and the muscle-to-fat ratio in animals by administering to the animals a therapeutically effective amount of a mixture of RR-ractopamine and SR-ractopamine is disclosed. Manufacturing methods for making RR/SR-ractopamine are presented.
US07723385B2
This invention relates to non-steroidal compounds that are modulators of androgen, glucocorticoid, mineralocorticoid, and progesterone receptors, and also to the methods for the making and use of such compounds.
US07723382B2
The present invention refers to a process for preparing a compound of general formula (A), as reported in the description, wherein R is a radical of a drug and R1-R12 are hydrogen or alkyl groups, m, n, o, q, r and s are each independently an integer from 0 to 6, and p is 0 or 1, and X is O, S, SO, SO2, NR13 or PR13 or an aryl, heteroaryl group, said process comprising reacting a compound of formula (B) R—COOZ (B) wherein R is as defined above and Z is hydrogen or a cation selected from: Li+, Na+, K+, Ca++, Mg++, tetralkylammonium, tetralkylphosphonium, with a compound of formula (C), as reported in the description, wherein R1-R12 and m, n, o, p, q, r, s are as defined above and Y is a suitable leaving group.
US07723381B2
Compounds of formula 1 and hetero derivatives thereof and the pharmacologically acceptable salts, enantiomers, racemates, hydrates, or solvates thereof, which are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin, or eyes, diseases of the peripheral or central nervous system or cancers, as well as pharmaceutical compositions which contain these compounds.
US07723374B2
Compounds are described that are active on PPARs, including pan-active compounds. Also described are methods for developing or identifying compounds having a desired selectivity profile.
US07723372B2
There are provided compounds of the general formulas wherein W, X, Y, R1, R2, R3, and R4 are as described herein. The compounds exhibit anticancer activity.
US07723363B2
A compound of general formula (I). A process for preparing this compound. A fungicidal composition comprising a compound of general formula (I). A method for treating plants by applying a compound of general formula (I) or a composition comprising it.
US07723362B2
The invention relates to compounds of formula wherein Het, A1, A2, A3, A4, D, W, T, Q, Y, X1, X2, R1, R2, R3, R4, k and m are as defined hereinabove, and, where applicable, to possible E/Z isomers, mixtures of E/Z isomers and/or tautomers thereof, in each case in free form or in salt form, to a process for the preparation of and to the use of those compounds, E/Z isomers, mixtures of E/Z isomers and/or tautomers, to pesticidal compositions in which the active ingredient has been selected from those compounds, E/Z isomers, mixtures of E/Z isomers and/or tautomers, in each case in free form or in agrochemically usable salt form, to a process for the preparation of and to the use of those compositions, to plant propagation material treated with those compositions, to a method of controlling pests, to intermediates and, where applicable, to possible E/Z isomers, mixtures of E/Z isomers and/or tautomers thereof, in each case in free form or in salt form, for the preparation of those compounds, E/Z isomers, mixtures of E/Z isomers and/or tautomers, and to a process for the preparation of and to the use of those intermediates and, where applicable, possible E/Z isomers, mixtures of E/Z isomers and/or tautomers thereof.
US07723350B2
The present invention relates to a compound of the following formula: where R1-R6, R10, Y, n, m, p, and q are as defined herein. Compounds and compositions of the present invention are useful for the treatment of diseases associated with the overexpression of CCR2.
US07723349B2
The present invention provides a compound of Formula I or Formula II: enantiomer, diastereomer, prodrug, solvate, metabolite, or pharmaceutically acceptable salt thereof, wherein constituent variables are provided herein. The compounds of Formula I and II are modulators of metalloproteases and are useful in treating diseases associated with metalloprotease activity such as arthritis, cancer, cardiovascular disorders, skin disorders, inflammation and allergic conditions.
US07723348B2
Selective PDE4 inhibition is achieved by aryl and heteroaryl pyrazole compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds such as rolipram and show selectivity with regard to inhibition of other classes of PDEs.
US07723346B2
Methods of providing neuroprotection are disclosed comprising administering a non-sedative barbiturate compound in an amount sufficient to achieve neuroprotection in a mammalian subject. Preferred compounds are in the family of diphenylbarbituric acid and analogs. Preferred doses for a neuroprotective effect exceed the dosage of a corresponding sedative barbiturate without sedative side-effects such as anesthesia and death.
US07723343B2
The present invention provides compounds of the formula wherein R1 and R2 have meaning as defined herein in the specification. The compounds of formula (I) are adenosine A2A receptor antagonists and, thus, may be employed for the treatment of conditions and diseases mediated by the adenosine A2A receptor activity. Such conditions include, but are not limited to, diseases of the central nervous system such as depression, cognitive function diseases and neurodegenerative diseases such as Parkinson's disease, senile dementia as in Alzheimer's disease or psychoses and stroke. The compounds of the present invention may also be employed for the treatment of attention related disorders such as attention deficit disorder (ADD) and attention deficit hyperactivity disorder (ADHD), extra pyramidal syndrome, e.g., dystonia, akathisia, pseudoparkinsonism and tardive dyskinesia, and disorders of abnormal movement such as restless leg syndrome (RLS) and periodic limb movement in sleep (PLMS); cirrhosis, and fibrosis and fatty liver; dermal fibrosis in diseases such as scleroderma; and the mitigation of addictive behavior. In particular, the compounds of the present invention may be employed to improve motor-impairment due to neurodegenerative diseases such as Parkinson's disease.
US07723339B2
The present invention relates to a combination comprising N-{5-[4-(4-methyl-piperazino-methyl) -benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine and an epothiione derivative; pharmaceutical composition comprising said combination; method of treatment comprising said combination; and commercial packages comprising said combination.
US07723338B2
The instant disclosure provides crystalline forms of 1-benzoyl-4-[2-[4,7-dimethoxy-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoethyl]-piperazine, salts and solvates thereof. The present disclosure also generally relates to pharmaceutical compositions comprising the crystalline form(s), as well of methods of using the crystalline form(s) in the treatment of HIV and/or AIDS, and methods for obtaining such crystalline form(s).
US07723334B2
Methods and compositions for treating humans suffering from, or preventing a human from suffering, a physiological or psychiatric disease, disorder, or a condition where inhibiting reuptake of norepinephrine is a benefit are disclosed. The compositions comprise a compound having a pharmacological selectivity of serotonin (Ki)/norepinephrine (Ki) of at least about 5000. Examples of such compounds include reboxetine, and more preferably optically pure (S,S) enantiomer of reboxetine. The methods generally include administration of a therapeutic amount of such compositions. Also disclosed are preparations of a medicament from the composition, and uses of the composition in a manufacture of the medicament to treat a human suffering from, or preventing a human from suffering, a physiological or psychiatric disease, disorder, or condition.
US07723330B2
Compounds of Formulas Ia and Ib, and stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting receptor tyrosine kinases and for treating disorders mediated thereby. Methods of using compounds of Formula Ia and Ib, and stereoisomers, geometric isomers, tautomers, solvates and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
US07723325B2
The present invention relates to compounds of formula I wherein G and R1 to R5 and R12 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prevention of diseases which are associated with the modulation of H3 receptors.
US07723321B2
This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: A, B, X, R1, R2, R3, R4, R5, R6, R7 and R8 are each as described herein or a pharmaceutically acceptable salt, and compositions containing such compounds and the use of such compounds in the treatment of a condition mediated by acid pump antagonistic activity such as, but not limited to, as gastrointestinal disease, gastroesophageal disease, gastroesophageal reflux disease (GERD), peptic ulcer, gastric ulcer, duodenal ulcer, NSAID-induced ulcers, gastritis, infection of Helicobacter pylori, dyspepsia, functional dyspepsia, Zollinger-Ellison syndrome, non-erosive reflux disease (NERD), visceral pain, heartburn, nausea, esophagitis, dysphagia, hypersalivation, airway disorders or asthma.
US07723316B2
Compositions and methods are provided for treatment of diseases involving unwanted neovascularization (NV). The invention provides treatments that control NV through selective inhibition of pro-angiogenic biochemical pathways, including inhibition of the VEGF pathway gene expression and inhibition localized at pathological NV tissues. Tissue targeted nanoparticle compositions comprising polymer conjugates and nucleic acid molecules that induce RNA interference (RNAi) are provided. The nanoparticle compositions of the invention can be used alone or in combination with other therapeutic agents such as VEGF pathway antagonists. The compositions and methods can be used for the treatment of NV diseases such as cancer, ocular disease, arthritis, and inflammatory diseases.
US07723307B2
Novel Amino Acid Derivatives and Pharmaceutical Uses Thereof Provided are novel compounds of Formula I: wherein ‘X’ represents an amino acid group, ‘n’ is an integer between 1 and 4, ‘R1’ represents benzyl, t-butyl or 9-fluorenylmethyl and ‘R2’ represents a tetramethylmercaptoimidazole derivative or —S+R3R4, wherein R3 and R4 each independently represent lower alkyl, or a pharmaceutically and/or veterinarily acceptable derivative thereof. Further provided are pharmaceutical formulations of the compounds and the use thereof in the preparation of a medicament for inhibiting diseases in which transglutaminase has been implicated. Advantageously, the medicament is for treating fibrosis, scarring and/or cancer. Additionally provided are methods, of inhibiting autoimmune diseases such as coeliac disease, neurodegeneration and chronic inflammatory diseases (e.g. of the joints including rheumatoid arthritis and osteoarthritis in a subject) and a method for preventing or treating rejection of a transplanted organ.
US07723306B2
The present invention relates to a spray-dried powder and method for its manufacture. A spray dried powder containing a pharmaceutical active substance and one or more 1,4 O-linked saccharose derivatives chosen from the compounds: 1,4 O-linked D-gal-saccharose (lactosucrose), 1,4 O-linked D-glu-saccharose (glucosyl sucrose) or 1,4 O-linked glu-glu-saccharose (maltosyl sucrose). Preferred combinations are such that they contain glucosyl and maltosyl sucrose.
US07723300B2
A progesterone regulator capable of modulating the non-genomic action of progesterone and methods of using the progesterone regulator are described. The progesterone regulator is useful for attenuating progesterone's inhibition of apoptosis and for the treatment of patients having a progesterone-responsive tissue disease such as endometriosis or cancer, particularly ovarian cancer.
US07723299B2
The present invention relates to methods for delivery of fusion polypeptides into cells. Methods are provided for local delivery of fusion polypeptides, e.g., through the skin, eye and the airway, to prevent allergic inflammation, airway hyper-responsiveness and to block T cell activation. Methods for delivery of fusion polypeptides to suppress graft rejection are also provided.
US07723297B2
This invention relates to human fibroblast growth factor (hFGF-21), and to variants thereof and to polynucleotides encoding FGF-21. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating liver disease such as cirrhosis and cancer, methods of treating conditions related to thymic function, and methods of treating conditions of the testis. The invention also relates to mouse fibroblast growth factor (mFGF-21), and to variants thereof and polynucleotides encoding mFGF-21.
US07723293B2
The present invention relates to methods of inducing or inhibiting the angiogenic process and promoting vessel growth or stabilization in an organ by modulating the trk receptor pathway. The present invention also relates to a method for treating a pathological disorder in a patient which includes administering a trk receptor ligand or an inhibitor or expression or activity of a trk receptor ligand. The present invention also relates to a method of screening for a modulator of angiogenesis, vessel growth, or vessel stabilization. Another aspect of the present invention is a method of diagnosing or monitoring a pathological disorder in a patient which includes determining the presence or amount of a trk receptor ligand or activation of a trk receptor ligand in a biological sample.
US07723289B2
Peptides and peptidomimetics capable of enhance endometrial receptivity, blocking activated but not basal immunity, inhibiting cell proliferation and creating a TH2 type cytokine bias are disclosed. The peptides and mimetics are based upon the C-terminal tetrapeptide of PIF peptides. Also disclosed are methods of using these peptides and peptidomimetics for therapeutic and diagnostic purposes.
US07723286B2
The present invention relates to the field of perfumery. More particularly, it concerns compounds comprising at least one β-oxy or β-thio carbonyl moiety capable of liberating a perfuming molecule such as, for example, an α,β-unsaturated ketone, aldehyde or carboxylic ester. The present invention concerns also the use of the compounds in perfumery as well as the perfuming compositions or perfumed articles comprising the invention's compounds.
US07723279B2
This invention relates to compositions containing lower (C1-C4) alcohol and a polymeric fluorosurfactant formulated for being dispensed as a foam product. More particularly, the invention relates to improved compositions formulated with polymeric fluorosurfactants with pendant perfluoroalkyl side chains of a fully fluorinated chain length of C1-C7. The compositions also relate to use for personal care, such as skin sanitizing and cleansing.
US07723271B2
A method for improving bonding and sealing in a well, comprising providing a wellbore, providing a pipe, coating an outside surface of the pipe with an adhesive thermoplastic resin, running the coated pipe into the wellbore, and causing the temperature of said wellbore to increase to a temperature greater than a melting temperature of said adhesive thermoplastic resin.
US07723264B2
The invention provides a method of treating a subterranean formation penetrated by a wellbore, the method comprising the steps of: (a) mixing a particulate and an active material to obtain an at least partially coated particulate, wherein: (i) water forms a contact angle of less than 90 degrees with a surface of the particulate, (ii) the active material is capable of forming a coating on the particulate, (iii) the active material forms a contact angle less than 90 degrees with the particulate, and (iv) water forms a contact angle of greater than 90 degrees with a layer of the active material; (b) mixing the at least partially coated particulate and a carrier fluid to obtain a treatment fluid; and (c) introducing the treatment fluid into the subterranean formation through the wellbore to deposit the at least partially coated particulate into the subterranean formation.
US07723258B2
A process of a catalytic combustion is disclosed. The process can be started at a cold temperature and then raised to a desired high temperature in a very short time by employing a noble metal catalyst dispersed on a supporting material. Moreover, a method for dispersing a noble metal catalyst used in the catalytic combustion is also disclosed for increasing a specific surface area of the catalyst so as to facilitate the catalytic combustion. Furthermore, a substance including a promoter dispersing a metal catalyst therewith, and a supporting material supporting the promoter with the metal catalyst is also disclosed, so that a contact surface area of the metal catalyst can be increased, thereby the catalytic combustion can be initiated within a very short period.
US07723257B2
Hydrocarbon transformations through radical reaction are carried out in presence of: a carbon nano/meso precursor, an aluminium containing support, and a lanthanide catalyst deposited on said aluminium containing support.
US07723256B2
Poly(propylene carbonates) are prepared from propylene oxide and CO2 with less than 10% cyclic propylene carbonate by product using cobalt based catalysts of structure preferably in combination with salt cocatalyst, very preferably cocatalyst where the cation is PPN+ and the anion is Cl− or OBzF5−. Novel products include poly(propylene carbonates) having a stereoregularity greater than 90% and/or a regioregularity of greater than 90%.
US07723236B2
Mixing ratio and flow rate of a first gaseous mixture supplied to a central portion of the substrate are set. Subsequently, etching is performed by changing a mixing ratio of a second gaseous mixture supplied to an outer peripheral portion of the substrate while a setting of the first gaseous mixture is fixed, thereby, setting the mixing ratio of the second gaseous mixture based on an etching result to make etching selectivities and shapes at the central portion and the outer peripheral portion of the substrate uniform. Then, etching is performed by changing a flow rate of the second gaseous mixture while settings of the first gaseous mixture and the mixing ratio of the second gaseous mixture are fixed, thereby, setting the flow rate of the second gaseous mixture based on etching results to make etching rates at the central portion and the outer peripheral portion of the substrate uniform.
US07723234B2
A method of removing polysilicon in preference to silicon dioxide and/or silicon nitride by chemical mechanical polishing. The method removes polysilicon from a surface at a high removal rate while maintaining a high selectivity of polysilicon to silicon dioxide and/or a polysilicon to silicon nitride. The method is particularly suitable for use in the fabrication of MEMS devices.
US07723219B2
In plasma immersion ion implantation of a polysilicon gate, a hydride of the dopant is employed as a process gas to avoid etching the polysilicon gate, and sufficient argon gas is added to reduce added particle count to below 50 and to reduce plasma impedance fluctuations to 5% or less.
US07723218B2
In a plasma CVD apparatus, unnecessary discharge such as arc discharge is prevented, the amount of particles due to peeling of films attached to a reaction chamber is reduced, and the percentage of a time contributing to production in hours of operation of the apparatus is increased while enlargement of the apparatus and easy workability are maintained. The plasma CVD apparatus is configured such that in a conductive reaction chamber 104 with a power source 113, a vacuum exhausting means 118, and a reaction gas introduction pipe 114, plasma 115 is generated in a space surrounded by an electrode 111, a substrate holder 112, and an insulator 120.
US07723217B2
The present invention relates to a method for manufacturing a gallium nitride single crystalline substrate, including (a) growing a gallium nitride film on a flat base substrate made of a material having a smaller coefficient of thermal expansion than gallium nitride and cooling the gallium nitride film to bend convex upwards the base substrate and the gallium nitride film and create cracks in the gallium nitride film; (b) growing a gallium nitride single crystalline layer on the crack-created gallium nitride film located on the convex upward base substrate; and (c) cooling a resultant product having the grown gallium nitride single crystalline layer to make the convex upward resultant product flat or bend convex downwards the convex upward resultant product and at the same time to self-split the base substrate and the gallium nitride single crystalline layer from each other at the crack-created gallium nitride film interposed therebetween.
US07723214B2
A multilayer structure, comprises a substrate and a layer of silicon and germanium (SiGe layer) deposited heteroepitaxially thereon having the composition Si1-xGex and having a lattice constant which differs from the lattice constant of silicon, and a thin interfacial layer deposited on the SiGe layer and having the composition Si1-yGey, which thin interfacial layer binds threading dislocations, and at least one further layer deposited on the interfacial layer.
US07723206B2
A photodiode in which increased sensitivity and speed are balanced. The photodiode includes: a semiconductor substrate; a plurality of active regions formed on the substrate by selective epitaxial growth; and a comb electrode provided for each of the plurality of active regions and in communication with each other to electrically connect the active regions together.
US07723204B2
A microelectronic assembly and a method for constructing a microelectronic assembly are provided. The microelectronic assembly may include a semiconductor substrate with an isolation trench (62) formed therein. The isolation trench (62) may have first and second opposing inner walls (74, 76) and a floor (78). First and second conductive plates (106) may be formed over the first and second opposing inner walls (74, 76) of the isolation trench (62) respectively such that there is a gap (90) between the first and second conductive plates (106). First and second semiconductor devices (114) may be formed in the semiconductor substrate on opposing sides of the isolation trench (62). The method may include forming a trench (62) in a semiconductor substrate, forming first and second conductive plates (106) within the trench, and forming first and second semiconductor devices (114) in the semiconductor substrate on opposing sides of the trench (62).
US07723188B2
A non-volatile memory device includes an upwardly protruding fin disposed on a substrate and a control gate electrode crossing the fin. A floating gate is interposed between the control gate electrode and the fin and includes a first storage gate and a second storage gate. The first storage gate is disposed on a sidewall of the fin, and the second storage gate is disposed on a top surface of the fin and is connected to the first storage gate. A first insulation layer is interposed between the first storage gate and the sidewall of the fin, and a second insulation layer is interposed between the second storage gate and the top surface of the fin. The second insulation layer is thinner than the first insulation layer. A blocking insulation pattern is interposed between the control gate electrode and the floating gate.
US07723165B2
There is provided a method of forming a component package. The method includes the steps of providing the die pad or heat sink, forming an isolation layer on the rear surface of the die pad or heat sink and encapsulating the die pad with encapsulating material in a mold cavity after forming the isolation layer on the rear of the die pad or heat sink.
US07723164B2
A process includes mating a first heat spreader and a second heat spreader, such that the first heat spreader at a mating surface and second heat spreader at a mating surface become parallel and adjacent. The process includes placing a first die in a first die recess of the first heat spreader, and placing a second die in a second die recess in the second heat spreader. The process includes reflowing thermal interface material between each die and respective heat spreader. Thereafter, the process includes separating the first heat spreader and the second heat spreader. A package is achieved by the process, with reduced thicknesses. The package can be disposed onto a mounting substrate. The package can be assembled into a computing system.
US07723163B2
A method of forming a pre-molded lead frame having increased stand-offs includes the steps of attaching a first tape to a first side of the lead frame and a second tape to a second side of the lead frame. The taped lead frame is placed in a mold and a first flow of mold compound is initiated. The first flow of the mold compound fills a space between the first tape and an upper mold chase of the mold. A second flow of the mold compound then is initiated. The second flow of the mold compound fills the spaces between a die pad and leads of the lead frame. The first and second tapes then are removed from the lead frame. Improved stand-offs are provided because the first tape was depressed by the first flow of the mold compound.
US07723160B2
A method and device for thermal conduction is provided. A thermal interface device and method of formation is described that includes advantages such as improved interfacial strength, and improved interfacial contact. Embodiments of thermal conduction structures are shown that provide composite thermal conduction and circulated liquid cooling. Embodiments are further shown that require simple, low numbers of manufacturing steps and reduced thermal interface thickness.
US07723158B2
In a method for producing bases with external contacts for surface mounting on circuit mounts, bases with external contacts are electrodeposited on semiconductor wafers or semiconductor chips. Subsequently, electrodeposited bases with external contacts are heat treated on the semiconductor wafers or the semiconductor chips at temperatures below the melting temperature of the deposited contact base material. Thereafter, a so-called RTP process is carried out in the form of a high-temperature interval in which the melting temperature is reached. Subsequently, the surfaces of the bases with external contacts are wet etched, the overall method being terminated by a cooling and drying operation. The bases with external contacts thus produced can be reliably surface mounted on circuit mounts.
US07723154B1
A p-type ZnO-based II-VI compound semiconductor layer has silver, potassium and/or gold dopants therein at a net p-type dopant concentration of greater than about 1×1017 cm−3. A method of forming the layer includes using an atomic layer deposition (ALD) technique. This technique includes exposing a substrate to a combination of gases: a first reaction gas containing zinc at a concentration that is repeatedly transitioned between at least two concentration levels during a processing time interval, a second reaction gas containing oxygen and a p-type dopant gas containing at least one p-type dopant species selected from a group consisting of silver, potassium and gold. A concentration of oxygen in the second reaction gas may also be repeatedly transitioned between at least two concentration levels. The concentration of zinc in the first reaction gas and the concentration of oxygen in the second reaction gas may be transitioned in an alternating sequence, so that relatively high zinc concentrations in the first reaction gas overlap with relatively low oxygen concentrations in the second reaction gas and vice versa.
US07723153B2
A method of forming an organic inverter includes providing a first metal layer having a first portion for coupling a source of an OFET to a first power supply voltage, a second portion for coupling a drain of the OFET to an output terminal and a first load resistor terminal, and a third portion for coupling a second load resistor terminal to a second power supply voltage, providing a semiconductor layer for overlapping a portion of the first and second first metal layer portions to form an OFET active area, and for overlapping a portion of the second and third metal layer portions to form a toad resistor, providing a dielectric layer for overlapping the active area of the OFET and the semiconductor area of the load resistor to isolates the first metal layer and semiconductor area from the second metal layer, and providing a second metal layer for overlapping the active area of the OFET to form a gate of the OFET and an input terminal.
US07723151B2
A CMOS image sensor and fabricating method thereof enhances a light-receiving capability of an image sensor by preventing poor light-refraction characteristics at the peripheral part of a microlens. The CMOS image sensor includes at least one microlens formed by anistropic etching to have a focusing centerline, a central lens portion, and a peripheral lens portion, wherein the focusing centerline passes through the central lens portion and wherein the peripheral lens portion surrounds the central lens portion. The central lens portion has a first convex curvature based on a first radius and the peripheral lens portion has second convex curvature based on a second radius, wherein the second radius is greater than the first radius.
US07723149B2
A color filter of an image sensor, an image sensor and a method for manufacturing the image sensor are disclosed, wherein shapes of respective unit color cells closely form various color patterns, such as a red color pattern, a green color pattern and a blue color pattern, within each unit color cell in a stripe type, and various colors such as red, green and blue required for image generation are produced, without interdependence of the respective unit color cells, are normally realized to induce a finished color filter array to smoothly express more colors, so that the resolution of a generated image in an optimal state is achieved.
US07723141B2
To produce a structure of a micro-electro-mechanical system (MEMS) in a hermetic cavity (38) of a microelectronic device (50), a prepared cover (30) and substrate (10) are bonded by means of silicon direct bonding (SDB). To optimise the preparation of surfaces by means of wet cleaning without impairing the properties of the MEMS (22), i.e. without causing adhesions, the MEMS structure (22) is not released during bonding, but attached to the base (12) by means of a sacrificial intermediate layer (16). Said layer is removed once bonding has been carried out by injecting HF vapour via a vent (40) opening into the cavity (38).
US07723134B2
A method of manufacturing a display device reduces damage to pad electrodes. The method includes: forming a thin film transistor in a pixel area on a first substrate and simultaneously forming a pad electrode in a pad area on the first substrate; forming a first pixel electrode connected to the thin film transistor and simultaneously forming a pad protection layer covering the pad electrode; and exposing the pad electrode by removing the pad protection layer.
US07723115B2
The present invention is a method to determine the TAN and TAN as a function of boiling point for a hydrocarbon feedstream using an electrospray ionization mass spectrometer (ESI-MS). The steps of the method include determining the signal as a function of mass from the ESI-MS while minimizing the formation of oligomers and fragmentation of the molecular species in the feedstream and then determining the TAN from the signals. The TAN is also determined as a function of boiling point.
US07723109B2
The present invention relates to the fields of molecular biology and plant biology. Specifically, the invention is directed to the methods for expressing spider silk proteins in plants and the synthesis and purification of spider silk proteins therefrom.
US07723106B2
A stroma-free, serum-free, and chemically defined medium and a method for mononuclear cell expansion ex vivo using the same. An exemplary medium includes a basal medium, a serum substitute, and a cytokine formula.
US07723104B2
The present invention regards cancer-specific control sequences that direct expression of a polynucleotide encoding a therapeutic gene product for treatment of the cancer. Specifically, the invention encompasses breast cancer-, prostate cancer-, and pancreatic cancer-specific control sequences. Two breast cancer-specific sequences utilize specific regions of topoisomerase IIα and transferrin receptor promoters, particularly in combination with an enhancer. The prostate cancer-specific and pancreatic cancer-specific control sequences utilize composites of tissue-specific control sequences, a two-step transcription amplification sequence, and a post-transcriptional control sequence. In more particular embodiments, these polynucleotides are administered in combination with liposomes.
US07723094B2
The invention provides a composition useful to prepare influenza viruses, e.g., in the absence of helper virus, using vectors which include PolII promoters and multiple ribozyme sequences.
US07723093B2
The present invention provides uracil-DNA glycosylase (UDG) gene originating from Psychrobacter sp. HJ147, and amino acid sequences deduced from the gene; expression and purification of Psp HJ147 UDG gene in Escherichia coli; and characterization of UDG obtained therefrom, and the use thereof in a polymerase chain reaction (PCR). The UDG according to the present invention has a specific activity of excising uracil bases in a uracil-containing DNA substrates at a low temperature, and is easily heat-inactivated. It thus can effectively eliminate cross contamination and carry-over contamination of PCR templates often occurring after a PCR process using dUTP. Therefore, it is useful for increasing preciseness (elimination of false positives), purity and amplification efficiency of PCR.
US07723092B2
A chondroitin polymerase having such properties that it transfers GlcUA and GalNAc alternately to a non-reduced terminal of a sugar chain from a GlcUA donor and a GalNAc donor, respectively, and the like; and a process for producing the chondroitin polymerase.
US07723090B2
An α-glucan phosphorylase having improved thermostability, which obtained by modifying natural α-glucan phosphorylase, and a method for producing this α-glucan phosphorylase having improved thermostability are provided. The natural α-glucan phosphorylase is derived from a plant, this α-glucan phosphorylase having improved thermostability has an amino acid residue which is different from that of the natural α-glucan phosphorylase in at least one position selected from the group consisting of a position corresponding to position 4 in a motif sequence 1L or 1H, a position corresponding to position 4 in a motif sequence 2, and a position corresponding to position 7 in a motif sequence 3L or 3H, and wherein the enzyme activity of α-glucan phosphorylase having improved thermostability at 37° C., after heating in a 20 mM citrate buffer (pH 6.7) at 60° C. for 10 minutes, is 20% or more of the enzyme activity of the α-glucan phosphorylase having improved thermostability at 37° C., before heating.
US07723082B2
The invention concerns novel isolated natural or synthetic polynucleotides and polypeptides coded by said polynucleotides, involved in the synthesis of diketopiperazine derivatives, vectors comprising said polynucleotides, micro-organisms transformed with said polynucleotides, uses of said polynucleotides and said polypeptides, as well as methods for the synthesis of diketopiperazine derivatives, including cyclodipeptides and diketopiperazine derivatives 3- and 6-substituted by α,β-unsaturated amino acid side chains.
US07723071B2
Recombinant forms of isolated and purified delta opioid receptors and methods to screen for compounds interactive with delta opioid receptors are described.
US07723067B2
The present invention relates to a process for secretory production of a foreign protein, in particular, transglutaminase by a coryneform bacterium. According to the present invention, a process is provided for the secretory production of a foreign protein, in particular, transglutaminase, by making a coryneform bacterium to produce an industrially useful foreign protein, in particular, transglutaminase and efficiently release the product extracellularly (i.e., secretory production). An intended foreign protein, in particular, transglutaminase, is produced by using an expression construct wherein the gene sequence of the intended foreign protein containing the pro-structure part, in particular, pro-transglutaminase gene sequence, is ligated to the downstream of a sequence encoding the signal peptide region from a coryneform bacterium, introducing this expressional genetic construct into a coryneform bacterium, culturing the thus transformed coryneform bacterium, and treating the extracellularly released protein with a protease, etc. to cleave and eliminate the pro-part.
US07723064B2
Methods are disclosed for monitoring patients utilizing Mean Platelet Component values during therapeutic intervention.
US07723063B2
The present invention concerns a method for the oxidative refolding of a hepcidin polypeptide to a form that is mature, bioactive and folded as in the native configuration and molecular mass; a method for measuring the level of native, bioactive hepcidin in a vertebrate animal; a method for measuring the level of hepcidin gene expression in a vertebrate animal; and a method for regulating the production of native, bioactive hepcidin in a vertebrate animal in vivo. The present invention also concerns an antibody or fragment thereof that specifically binds to a continuous, discontinuous, and/or conformational epitope of a mature and bioactive hepcidin folded as in the native configuration; and a pharmaceutical composition that includes the antibody or a hepcidin polypeptide and that provides antimicrobial, agonistic, or antagonistic activities in vivo in a vertebrate animal.
US07723062B1
The invention provides compositions and methods for the detection and quantification of Wolbachia antibodies, antibody fragments, and polypeptides.
US07723058B2
The present invention describes a test system for the determination of in-vivo active hemostasis proteases in biological fluids and the use thereof to determine the in-vivo activation of hemostasis or to diagnose pancreatitis. EDTA and/or EGTA is added to the biological sample to prevent artificial activation of the hemostasis proteases. Arginine and/or guanidine can also be added to the biological sample.
US07723057B1
A screening assay for selecting macromolecules that interfere with the binding of a sulfated GAG to beta amyloid, the assay comprising affixing a sulfated GAG to a substrate, co-incubating the macromolecule and a known amount of beta amyloid with the sulfated GAG, determining the amount of beta amyloid bound to the sulfated GAG affixed to the substrate; wherein the macromolecule will be one which interferes with the binding of the sulfated GAG to beta amyloid.
US07723056B1
Lipid vesicle particles capable of being targeted to a cell type of interest, said particle incorporating a peptide which is responsive to a predetermined metabolic signal from the targeted cell so as to modulate the permeability of the particle, said particle further incorporating a species to be targeted to the cell which is activated on said modulation of permeability. The particles may be used in methods for detecting cells, methods of treating cells and also therapeutically.
US07723053B2
A method for identifying a selective persistent Na+ channel blocker by measuring the ability of the blocker to reduce or inhibit a persistent Na+ current to a greater degree than a transient Na+ current. Aspects of the present method provide Na+ depletion/repletion methods for identifying a selective blocker of a persistent Na+ channel, hyperpolarization methods for identifying a blocker of a persistent Na+ channel, and Na/K ATPase pump inhibitor methods for identifying a selective blocker of a persistent Na+ channel.
US07723048B2
The present invention relates to predicting therapeutic response of treating patients suffering from itching and puritis mediated by cutaneous lymphocyte antigen positive T cells in atopic dermatitis. The invention also includes methods of predicting a therapeutically responsive patient population.
US07723046B2
The present inventors conducted a similarity search of the amino acid sequence of known G protein-coupled receptor proteins in GenBank, and obtained a novel human GPCR gene “BG37”. cDNA containing the ORF of the gene was cloned and its nucleotide sequence was determined. Moreover, novel GPCR “BG37” genes from mouse and rat were isolated. Use of the novel GPCR of the present invention enables screening of ligands, compounds inhibiting the binding to a ligand, and candidate compounds of pharmaceuticals which can regulate signal transduction from the “BG37” receptor.
US07723044B2
This invention generally relates to apparatus and methods for high-throughput, reproducible and inexpensive detection of virus infection using multiplexing technologies such as slide-based, microtiter plate-based and membrane-based microarrays and beads technologies. The apparatus and methods allow simultaneous detection of multiple viral infections in a plurality of test samples.
US07723043B2
Methods for diagnosing and treating prostate cancer are disclosed. In practicing the method, a subject's body-fluid sample is assayed for GPC3 protein, and the GPC3 level observed is used in determining whether the subject has an elevated GPC3 level associated with prostate cancer. Patients with such elevated levels may be treated, in accordance with the invention, with a variety of GPC3-related immunotherapy agents.
US07723036B2
The present invention encompasses methods for predicting metastasis in cancer by assessing the structure of the complement protein C1qA. The methods may encompass examining either protein or nucleic acids, and may further include making treatment decisions based on the predictive methods.
US07723027B2
A method for the diagnosis of SMEI in a patient comprising: (1) detecting an alteration in the SCN1A gene, including in a regulatory region of the gene, in a patient sample; (2) ascertaining whether the alteration is known to be SMEI associated or non-SMEI associated; and (3) (a) establishing a diagnosis of a high probability of SMEI where the alteration is known to be SMEI associated; or (b) establishing a diagnosis of a low probability of SMEI where the alteration is non-SMEI associated; or (e) or, if not known to be either, (i) considering genetic data for parents and/or relatives; (ii) establishing whether the alteration has arisen de novo or is inherited; and (iii) establishing a diagnosis of a low probability of SMEI where the alteration is inherited but a diagnosis of a high probability of SMEI if the alteration is de novo.
US07723015B2
In one embodiment, the invention provides a method for manufacturing an array of interferometric modulators. Each interferometric modulator comprises first and second optical layers which when the interferometric modulator is in an undriven state are spaced by a gap of one size, and when the interferometric modulator is in a driven state are spaced by a gap of another size, the size of the gap determining an optical response of the interferometric modulator. The method comprises fabricating interferometric modulators of a first type characterized by the size of the gap between its first and second optical layers when in the undriven state; fabricating interferometric modulators of a second type characterized by the size of the gap between its first and second optical layers when in the undriven state; and fabricating modulators of a third type characterized by the size of the gap between its first and second optical layers when in the undriven state, wherein fabricating the interferometric modulators of the first, second, and third types comprises using a sequence of deposition and patterning steps of not more than 9 masking steps to deposit and pattern layers of material on a substrate.
US07723013B2
A negative-acting photolithographic printing plate precursor has a unique negative-acting photosensitive composition on a surface. The photosensitive composition contains an acetal polymer, an infrared absorbing dye or pigment, a crosslinking agent for the acetal resin and a photosensitive chemical acid progenitor, and the acetal polymer has within its backbone a structure comprising a particular polymeric moiety derived from a polyvinyl alcohol backbone.
US07723010B2
There is provided polymeric particles having a particle size between about 60 nm and about 1000 nm and comprising a polymer, the polymer comprising a hydrophobic backbone, a near infrared absorbing segment having attached thereto a near infrared absorbing chromophore having an absorption peak between about 700 nm and about 1100 nm; and a near infrared transparent segment. Method of manufacture these particles are also provided. A coating composition comprising the above-polymeric particles and a reactive iodonium oligomer is also provided. Finally, a negative-working lithographic offset printing plate comprising a substrate; a hydrophilic under layer; and a laser imageable upper layer, wherein the laser imageable upper layer comprises the above polymeric particle is also provided.
US07723009B2
A mask having features formed by self-organizing material, such as diblock copolymers, is formed on a partially fabricated integrated circuit. Initially, a copolymer template, or seed layer, is formed on the surface of the partially fabricated integrated circuit. To form the seed layer, diblock copolymers, composed of two immiscible blocks, are deposited in the space between copolymer alignment guides. The copolymers are made to self-organize, with the guides guiding the self-organization and with each block aggregating with other blocks of the same type, thereby forming the seed layer. Next, additional, supplemental diblock copolymers are deposited over the seed layer. The copolymers in the seed layer guide self-organization of the supplemental copolymers, thereby vertically extending the pattern formed by the copolymers in the seed layer. Block species are subsequently selectively removed to form a pattern of voids defined by the remaining block species, which form a mask that can be used to pattern an underlying substrate. The supplemental copolymers augment the height of the copolymers in the seed layer, thereby facilitating the use of the copolymers for patterning the underlying substrate.
US07723004B2
A toner having an amorphous resin, a crystalline resin, and a colorant, wherein the crystalline resin has a melting temperature of at least 70° C. and a recrystallization point of at least 47° C. exhibits improved document offset properties and improved heat cohesion. Annealing the toner further improves the heat cohesion and morphology of the toner.
US07723002B2
A toner for electrostatic image development, comprising a resin binder comprising a crystalline polyester; a releasing agent comprising a wax having a melting point of from 60 to 85° C. and a penetration at 25° C. of from 4 to 10; and a colorant. The toner for electrostatic image development can be used, for instance, for the development of a latent image formed in electrophotography, electrostatic recording method, electrostatic printing method or the like.
US07723001B2
An electrophotographic toner includes toner parent particles containing a binder resin, a colorant and a charge control agent; and an external additive added to the surface of the toner parent particles. The toner further includes positively chargeable silica and polymer beads in addition to large particle diameter silica, small particle diameter silica and titanium oxides. Thus, the toner can maintain its charge quantity and distribution stably even during environmental changes and after long image printing times, thereby preventing the contamination of the non-image part and the filming.
US07722998B2
A reflective mask and a reflective mask blank that can form a fine mask pattern with high accuracy in shape, achieve a sufficient contrast in a pattern inspection, and enable a pattern transfer with high accuracy. On a substrate (11), a multilayer reflective film (12) for reflecting an exposure light, a buffer layer (13), and an absorber layer for absorbing the exposure light are successively deposited in this order. This absorber layer has a layered structure composed of an uppermost layer (15) and a lower layer (14) other than it. The uppermost layer (15) exhibits a reflectance of 20% or less with respect to a light having an inspection wavelength for use in an inspection of a pattern formed in the absorber layer and further is formed of an inorganic material having a resistance against an etching condition in forming a pattern in the lower layer.
US07722996B2
A polymer electrolyte fuel cell system is disclosed, comprising a fuel cell having a predetermined power generation portion configured to operate at a predetermined temperature to generate an electric power using a fuel gas and an oxidizing gas supplied to said fuel cell, and a humidifier configured to humidify the fuel gas and the oxidizing gas, wherein the humidifier is configured to humidify the fuel gas and the oxidizing gas to allow the fuel gas and the oxidizing gas to have dew points higher than the predetermined temperature, the humidified fuel gas and oxidizing gas having the dew points higher than the operating temperature being supplied to the fuel cell.
US07722995B2
A carbonate-modified silane or siloxane is combined with a non-aqueous solvent and an electrolyte salt to form a non-aqueous electrolytic solution, which is used to construct a secondary battery having improved charge/discharge characteristics.
US07722988B2
A lithium electrochemical cell design incorporating a low molality electrolyte including LiI is disclosed. The resulting cell delivers excellent performance under a wide range of temperatures, conditions and drain rates.
US07722984B2
A pouch type secondary battery having enhanced reliability by protecting the battery from external impacts is described. A reinforcement structure may be installed on a pouch casing and an electrode assembly housed in the pouch casing. Short-circuits inside the pouch casing may be minimized. The pouch type secondary battery has an electrode assembly with positive and negative electrode plates with a separator interposed therebetween, and positive and negative terminal portions extending from the positive and negative electrode plates. A first reinforcement member is closely adhered to one or more planes of the electrode assembly. A second reinforcement member may be adhered to the pouch casing and used with or without the first reinforcement member.
US07722983B2
Electrode assemblies easily impregnated with an electrolyte are provided. A sealing tape attached to the outer circumference of the electrode assembly comprises a material having an affinity for the electrolyte. Alternatively, the entire sealing tape or a portion of the tape is coated with the material. In another alternative, the surface of the sealing tape is rough, thereby improving wetting of the tape by the electrolyte and diffusion of the electrolyte into the tape. In another embodiment, first and second insulating plates comprise a material having an affinity for the electrolyte. In another alternative, the insulating plates comprise a mixture of a material having an affinity for the electrolyte and polypropylene or polyethylene. Alternatively, the surfaces of the insulating plates are coated with the material or with a surfactant that reduces the surface tension of the electrolyte.
US07722982B2
This invention includes a battery pack having an improved battery retention system for coupling to another device, like a desktop charger. The battery pack, which includes one rechargeable cell and optional circuitry, has an exterior housing that is generally rectangular in cross section. The exterior housing, which includes major faces and intersection seams, has at least two female slots that project inward at an angle that is non-orthogonal to the major faces or intersection seams. These non-orthogonal slots, when coupling to corresponding non-orthogonal rails in the pocket of a battery charger, allow batteries of various sizes to be inserted into a single charger pocket with reliable and consistent electrical connections between the electrical contacts of the pocket and the charging terminals of the battery. Electrical contacts may be disposed within the non-orthogonal slots, thereby improving both the function and aesthetic appearance of the battery pack.
US07722980B2
A solid oxide fuel cell that directly utilizes a flame according to the present invention has a solid oxide substrate, a cathode electrode layer formed on one surface, and an anode electrode layer 3 formed on the opposite surface and a platinum mesh is embedded in the entire surfaces of the solid cathode electrode layer and the anode electrode layer. An oxide layer covers the entire periphery of the solid oxide substrate from the end part of the cathode electrode layer to the end part of the anode electrode layer. Due to the platinum mesh and the oxide layer, thermal shock due to rapid heating by a flame is alleviated and cracking in the solid oxide substrate is prevented from occurring.
US07722977B2
A terminal plate, an insulating plate, and an end plate are stacked on a stack body. The terminal plate has current collectors at least at lower portions of an oxygen-containing gas supply passage, a coolant supply passage, a fuel gas discharge passage, a fuel gas supply passage, a coolant discharge passage, and an oxygen-containing gas discharge passage. The current collectors contact the water generated in the reaction or a coolant for collecting electricity.
US07722965B2
The present invention provides an organic electroluminescence device including an organic layer comprising an emissive layer; a pair of electrodes comprising an anode and a cathode, and sandwiching the organic layer, wherein at least one of the electrodes is transparent; a transparent layer provided adjacent to a light extracting surface of the transparent electrode; and a region substantially disturbing reflection and retraction angle of light provided adjacent to a light extracting surface of the transparent layer or in an interior of the transparent layer, wherein the transparent layer has a refractive index substantially equal to or more than the refractive index of the emissive layer.
US07722962B2
A solder foil formed from a material comprising particles of Cu, etc. as metal particles and Sn particles as solder particles by rolling is suitable for solder bonding at a high temperature side in temperature-hierarchical bonding, and semiconductor devices and electronic devices produced by use of such solder bonding have distinguished reliability of mechanical characteristics, etc.
US07722952B2
A composite configured to release refrigerant therefrom comprises a substrate material comprising polarized fibers of glass, polyamide, phenylene sulfide, carbon or graphite having bonded thereon a metal compound comprising a complex compound of a polar gaseous refrigerant and a metal salt and/or a hydrated metal hydroxide and/or a metal hydroxide of a metal selected from the group consisting of alkali metal, alkaline earth metal, transition metal, zinc, cadmium, tin, aluminum, or two or more thereof, at a concentration of at least about 0.3 grams/cc of open substrate material volume, and a coating composition thereon configured to prevent release of internal gaseous refrigerant therethrough at ambient temperatures and pressure and capable of penetration of gaseous refrigerant therethrough from the composite interior at temperatures causing internal gas pressures of 15% or more above exterior pressure for such refrigerant release.
US07722942B2
The present invention relates to an Ag alloy film. Particularly, it is preferably used as a reflective film or semi-transmissive reflective film for an optical information recording medium having high thermal conductivity/high reflectance/high durability in the field of optical information recording media, an electromagnetic-shielding film excellent in Ag aggregation resistance, and an optical reflective film on the back of a reflection type liquid crystal display device, or the like. The Ag alloy film of the present invention comprises an Ag base alloy containing Bi and/or Sb in a total amount of 0.005 to 10% (in terms of at %). Further, the present invention relates to a sputtering target used for the deposition of such an Ag alloy film.
US07722941B2
An optical data store is specified, having a data storage layer with a non-toxic and biodegradable polymer as light-sensitive storage medium which has photo-inducible anisotropy, for the induction of which a threshold value of the optical intensity has to be exceeded. The light-sensitive material is preferably bacteriorhodopsin which, by way of example, is immobilized in a manner embedded in a suitable matrix material or, if appropriate, in a crosslinked manner. The storage medium permits a high storage density and can be applied in a simple manner, for instance by printing onto a substrate.
US07722938B2
This disclosed invention relates to a dry paint transfer laminate, comprising: a dry paint film layer comprising a binder and a pigment, the dry paint film layer having an upper surface and a lower surface; an adhesive layer overlying the upper surface of the dry paint film layer; and a release liner overlying the lower surface of the dry paint film layer.
US07722937B2
In accordance with one aspect of the invention, a material, such as a plastic film, is used to separate independent food elements. The independent food elements and the separation material are packaged together using a unifying outer package. At a point in time when the customer decides to eat the food, the outer package is opened and the film that separates the different food elements is removed, either manually or automatically. This marks the first point in time that the separate elements come into contact with each other. Therefore, the food product is maintained at the highest level of integrity until the time of usage by the customer. Methods and a machine for layering the contents of the packages so as to form a completed assembly for the packaged elements is also described.
US07722935B2
A modified polymer which can serve as a raw material of novel reverse dispersion retardation films is provided, the modified polymer having no need to select a plurality of monomers or polymers in order to realize a reverse dispersion and having no problems concerning glass transition temperature or the like in drawing treatment. A polymer having a polyol skeleton as its main chain is caused to react with a compound for modification such as an aromatic carboxylic acid hydride. Through this reaction, a modified polymer in which a chemical group such as an aromatic carbonyl group is bonded to an oxygen atom in a side chain of the polyol skeleton is prepared. For example, polyvinyl alcohols and benzoyl chloride can be used as the polymer and the compound for modification, respectively. The chemical group may be a benzoyl group. When this modified polymer is formed into a film and then subjected to drawing treatment, a retardation film which exhibits a reverse wavelength dispersion characteristic can be obtained.
US07722929B2
A sealing method for decreasing the time it takes to hermetically seal a device and the resulting hermetically sealed device (e.g., a hermetically sealed OLED device) are described herein. The sealing method includes the steps of: (1) cooling an un-encapsulated device; (2) depositing a sealing material over at least a portion of the cooled device to form an encapsulated device; and (3) heat treating the encapsulated device to form a hermetically sealed device. In one embodiment, the sealing material is a low liquidus temperature inorganic (LLT) material such as, for example, tin-fluorophosphate glass, tungsten-doped tin fluorophosphate glass, chalcogenide glass, tellurite glass, borate glass and phosphate glass. In another embodiment, the sealing material is a Sn2+-containing inorganic oxide material such as, for example, SnO, SnO+P2O5 and SnO+BPO4.
US07722927B2
A device and a method for facilitating the deposition and patterning of organic materials onto substrates utilizing the vapor transport mechanisms of organic vapor phase deposition is provided. The device includes one or more nozzles, and an apparatus integrally connected to the one or more nozzles, wherein the apparatus includes one or more source cells, a carrier gas inlet, a carrier gas outlet, and a first valve capable of controlling the flow of a carrier gas through the one or more source cells. The method includes moving a substrate relative to an apparatus, and controlling the composition of the organic material and/or the rate of the organic material ejected by the one or more nozzles while moving the substrate relative to the apparatus, such that a patterned organic layer is deposited over the substrate.
US07722922B2
An coating apparatus, wherein the apparatus applies a coating, onto a surface of an aluminum alloy member for a heat exchanger to be assembled by brazing, with a top-feed-type roll transfer system having at least three rolls, the coating being obtained by mixing into an organic binder a metal powder, a flux powder, a powder mixture thereof, or a compound containing a metal component and a flux component, wherein rotation directions of transfer rolls of the apparatus arranged above a surface to be coated of an aluminum alloy extruded member that moves in a horizontal direction, satisfy a relationship in which a rotation direction of a coated-metal roll for coating, which rotates in a direction opposite to a moving direction of the extruded member, and a rotation direction of a metal roll for adjusting an adhesion amount of the coating by contacting with the above roll, are opposite to each other; and a method of producing an aluminum alloy heat exchanger member using the apparatus; and an aluminum alloy heat exchanger member.
US07722920B2
Described are methods of making an electronic device, such as an RFID tag, including fabricating an antenna by depositing an electrically conductive polymer onto a substrate. The electrically conductive polymer is electrically connected to an electronic component, such as an IC chip or a diode. The electronic component may be placed on the substrate before or after the electrically conductive polymer is deposited. Once deposited, the electrically conductive polymer is cured. The electrically conductive polymer may be deposited in a number of ways, such using a mask having a desired pattern and applying the electrically conductive polymer to the mask, by screen printing the electrically conductive polymer or by printing the electrically conductive polymer using ink jet printing techniques.
US07722914B2
Pharmacologically active, easy-to-deploy, biomechanically compatible, inflatable endovascular, drug-eluting stent are formed of a primary expandable polymeric or metallic construct, intimately mantled with a biomechanically compatible, polymeric microporous, microfibrous, compliant, stretchable fabric formed by direct electrospinning onto the outside surface of the primary construct using at least one polymer solution containing at least one active compound, selected from those expected to control key biological events leading to in-stent restenosis.
US07722913B2
An implantable enzyme-based monitoring system suitable for long term in vivo use to measure the concentration of prescribed substances such as glucose is provided. In one embodiment, the implantable enzyme-based monitoring system includes at least one sensor assembly, an outer membrane surrounding the sensor assembly and having a window therein, and a polymeric window cover affixed to the outer membrane and covering the window. Preferably, the outer membrane of the monitoring system is silicone and the window cover is a polymer of 2-hydroxyethyl methacrylate (HEMA), N,N,-dimethylaminoethyl methacrylate (DMAEMA) and methacrylic acid (MA). Also provided herein is an implantable enzyme-based monitoring system having at least one sensor assembly, an outer membrane surrounding the sensor assembly and a coating affixed to the exterior surface of the outer membrane, wherein the coating resists blood coagulation and protein binding to the exterior surface of the outer membrane. Preferably, the coating is polyethylene glycol (PEG) and heparin in an 80:20 molar ratio. Finally, provided herein is a method of coating the exterior surface of the outer membrane of an implantable enzyme-based monitoring system comprising the steps of forming hydroxyl groups on the silicone surface by plasma etching; reacting the silicone surface with amino functionalized silane, thereby forming amino groups on the silicone surface; simultaneously, covalently binding polyethylene glycol (PEG) and heparin to the amino groups; and ionically binding heparin to the monitoring system surface.
US07722911B2
The invention provide methods and materials for producing nutritious pet chews comprising an edible thermoplastic comprising from 45 to 80 wt. % starch selected from one or more potato and non-potato starches wherein said starch comprises at least 28% amylose as determined by size exclusion chromatography if less than 50% of said starch is potato starch or at least 20% amylose as determined by size exclusion chromatography if greater than or equal to 50% of said starch is potato starch; from 5 to 25 wt. % plasticizer; 2% to 15 wt % of a humectant and from 5 to 25 wt. % water.
US07722907B2
One embodiment includes a package system containing a main container with a smaller container nested in it. The smaller container is filled with a secondary food item designed to be mixed into the primary food item. The smaller container is placed within the main container. The area of the main container not occupied by the smaller container includes a main food item. Both containers are sealed with one film. Before consumption, a consumer will place the package in a microwave to heat. Once heated, the smaller container is removed from the main container, creating space in the main container previously occupied by the smaller container. The main food item in the main container will re-position creating space between the top of the main food item to the edge of the main container. The secondary item can be added into the main container without overflowing out of the main container.
US07722906B2
The present invention provides novel compositions comprising a Nigella sativa L. polyunsaturated fatty acid fraction. The present invention also provides novel compositions, particularly topical compositions, comprising octadecadienoic acid and/or octadecenoic acid. The present invention provides novel methods for treating and preventing fungal infections, bacterial infections, skin conditions, anal fissures, hemorrhoids, inflammation, pain, allergic reactions, and septic wounds by administering, preferably topically administering, an effective amount of a composition comprising octadecadienoic acid and/or octadecenoic acid, or a composition comprising the Nigella sativa L. polyunsaturated fatty acid fraction.
US07722905B2
A method is provided for reducing odor of excreta of a companion animal. The method comprises causing the animal to ingest a composition comprising an excreta odor reducing effective amount of a zingiberaceous spice such as ginger or an extract thereof, or an excreta odor reducing effective amount of fiber together with another odor reducing agent.
US07722897B2
A patch comprises a support having electrostatic properties. The periphery of the support is coated with an adhesive material, and all or part of the non-adhesive surface of the support is directly covered with at least one biologically active substance in the form of particles. The particles remain in contact with the non-adhesive part of the support as a result of the electrostatic forces.
US07722887B1
The present invention relates to detoxified and immunologically active proteins (“mutant LTs”) having mutated amino acid sequences of heat-labile enterotoxin of E. coli, DNA sequences encoding the mutant LTs, recombinant expression vectors comprising the DNAs, recombinant microorganisms transformed with the recombinant expression vectors, process for preparing the mutant LTs and pharmaceutical application of the said protein as immunogenic antigens for vaccination and as adjuvants for anti-body production. In contrast to wild-type LT, the mutant LTs did not induce any toxic activities. The mutant LTs elicited high and comparable levels of anti-LT antibodies when delivered either intragastrically or intranasally, inducing systemic and local responses in serum and fecal extracts. Thus, they might be useful for the development of a novel diarrheal vaccine in humans and animals. In addition, the antibody production ability using mutant LTs as an adjuvant may be effective for prevention and treatment of various diseases.
US07722883B2
The genome sequences and the nucleotide sequences coding for the PWD circovirus polypeptides, such as the circovirus structural and non-structural polypeptides, vectors including the sequences, and cells and animals transformed by the vectors are provided. Methods for detecting the nucleic acids or polypeptides, and kits for diagnosing infection by a PWD circovirus, also are provided. Method for selecting compounds capable of modulating the viral infection are further provided. Pharmaceutical, including vaccine, compositions for preventing and/or treating viral infections caused by PWD circovirus and the use of vectors for preventing and/or treating diseases also are provided.
US07722881B2
Chimeric somatostatin-based polypeptides, polynucleotides used to encode the polypeptides, the methods for isolating and producing the polypeptides and the uses thereof are provided. In addition, low cost adjuvants for enhanced immunogenic response are provided. Vaccinations that include both chimeric somatostatin-based polypeptides and novel adjuvants are included, useful in facilitating farm animal productivity.
US07722873B2
The invention relates to transgenic non-human animals capable of producing high affinity human sequence antibodies. The invention is also directed to human sequence antibodies specific for human antigens, such as, human CD4. The invention also is directed to methods for producing human sequence antibodies.
US07722861B2
Non-naturally occurring mycobacteria in the Mycobacterium tuberculosis complex are provided. These mycobacteria have a deletion of an RD1 region or a region controlling production of a vitamin, and exhibit attenuated virulence in a mammal when compared to the mycobacteria without the deletion. Also provided are non-naturally occurring mycobacteria that have a deletion of a region controlling production of lysine, and mycobacteria comprising two attenuating deletions. Vaccines comprising these mycobacteria are also provided, as are methods of protecting mammals from virulent mycobacteria using the vaccines. Also provided are methods of preparing these vaccines which include the step of deleting an RD1 region or a region controlling production of a vitamin from a mycobacterium in the M. tuberculosis complex.
US07722860B2
The invention provides methods for inducing an immune response in a vertebrate host against a protozoan parasite, comprising administering to the host a live protozoan parasite that is genetically engineered to disrupt a stage-specific gene function that is required by the protozoan parasite to establish a secondary infection in the vertebrate host. Representative protozoan parasites belong to the phyla Apicomplexa and Kinetoplastida. The vertebrate host may be a mammal or a bird.
US07722858B2
The present invention provides a method of determining whether an individual is at risk for atherosclerosis, comprising the step of measuring the level of cLDL and/or autoantibody to cLDL in a sample obtained from this individual. The invention further discloses a method of reducing carbamylation in an individual with a monomeric amino acid or other enzymatic or non-enzymatic inhibitors of carbamylation. The instant invention also provides a method to decrease the level of cLDL by direct elimination of cLDL from the blood or plasma of an individual. The invention also provides a method of treating or preventing atherosclerosis in an individual by inhibiting aggregation and/or deposition of cLDL in the individual.
US07722857B2
An immunoadjuvant comprising one kind or two or more kinds of immunostimulating substances carried separately by two or more kinds of different microparticle immunostimulating substance carriers, and comprising at least a combination of (a) an inorganic substance such as microparticle calcium phosphate having a size phagocytizable by cells, and (b) precipitates of a soluble protein and a mucopolysaccharide formed by coacervation as the microparticle immunostimulating substance carriers, which is highly safe and can exhibit potent immunoadjuvant activity.
US07722852B2
Processes for the thermal reduction of sulfur dioxide to elemental sulfur are described and disclosed. The processes described include three general reaction sections, including the reaction furnace portion where the SO2-containing stream is combusted, the hydrogenation portion wherein the effluent from the reaction furnace is hydrogenated over an appropriate catalyst, and a Claus conversion portion, wherein residual H2S and SO2 are further reacted to produce additional elemental sulfur.
US07722849B2
Pyrogenic silicon dioxide powder with a BET surface area of 30 to 90 m2/g, a DBP index of 80 or less, a mean aggregate area of less than 25000 nm2 and a mean aggregate circumference of less than 1000 nm, wherein at least 70% of the aggregates have a circumference of less than 1300 nm. It is prepared by mixing at least one silicon compound in vapor form, a free-oxygen-containing gas and a combustible gas in a burner of known construction, igniting this gas mixture at the mouth of the burner and burning it in the flame tube of the burner, separating the solid obtained from the gas mixture and optionally purifying, wherein the oxygen content of the free-oxygen-containing gas is adjusted so that the lambda value is greater than or equal to 1, the gamma value is between 1.2 and 1.8, the throughput is between 0.1 and 0.3 kg SiO2/m3 of core gas mixture and the mean normalized rate of flow of gas in the flame tube at the level of the mouth of the burner is at least 5 m/s. The powder can be used as a filler. A dispersion containing the powder according to the invention. The powder can be used as a filler in rubber, silicone rubber and plastics. The dispersion can be used to prepare glass items.
US07722847B2
An aqueous hydrogen peroxide solution containing i) less than 50 wppm alkali metals, alkaline earth metals or combinations thereof in total, irrespective whether the alkali or alkaline earth metals are present in cationic or complex form; ii) less than 50 wppm of amines having a pkB of less than 4.5 or the corresponding protonated compounds in total; and iii) at least 100 wppm anions or compounds that can dissociate to form anions in total, where the wppm are based on the weight of hydrogen peroxide and the concentration of hydrogen peroxide is more than 50% by weight based on the total weight of the hydrogen peroxide solution. A process for preparation of said hydrogen peroxide solution and the use of said solution in a process for epoxidation of olefins is also disclosed.
US07722846B2
Provided is a method for preparing an electroconductive mayenite type compound with good properties readily and stably at low cost.A production method of an electroconductive mayenite type compound comprising a step of subjecting a precursor to heat treatment, is a method for preparing an electroconductive mayenite type compound, comprising a step of subjecting a precursor to heat treatment; wherein the precursor is a vitreous or crystalline material, which contains Ca and Al, in which a molar ratio of (CaO:Al2O3) is from (12.6:6.4) to (11.7:7.3) as calculated as oxides, and in which a total amount of CaO and Al2O3 is at least 50 mol %, and wherein the heat treatment is heat treatment comprising holding the precursor at a heat treatment temperature T of from 600 to 1415° C. and in an inert gas or vacuum atmosphere with an oxygen partial pressure PO2 in a range ofPO2≦105×exp [{−7.9×l04/(T+273)}+14.4] in the unit of Pa.
US07722839B2
An apparatus and method are provided to rapidly thaw and heat frozen bags of biological materials, such as plasma. The apparatus has a hollow bladder having a flexible wall that is placed in contact with the bag. A circulation system draws fluid from a reservoir and fills the bladder with the fluid. The circulation system also drains fluid from the bladder. A heater in the reservoir heats the fluid before the fluid enters the bladder. As heated fluid flows through the bladder, heat is transferred through the bladder wall to the plasma bag to thaw the biological material. The bladder wall expands against the plasma bag as the bladder fills with fluid, and contracts from the plasma bag as the bladder is drained. The expansion and contraction of the bladder wall agitates the plasma bag and biological material to accelerate the thawing process.
US07722836B1
The Chemical-agent Access and Neutralization System (CANS) of the present invention is a small, portable, single-use, disposable chemical treatment apparatus that is used to access and treat Chemical Agent Identification Set (CAIS) ampoules, bottles and/or containers that contain vesicant agents, or chemical warfare agents such as mustard or Lewisite. The apparatus and method of use of the present invention provides a resultant treatment residue that remains totally contained in the CANS treatment container and is safe for disposal. The CANS treatment container can be over packed into a Department of Transportation (DOT) certified shipping container, and shipped to permitted hazardous waste management facilities for ultimate disposal.
US07722835B2
A closed and yet flexible and easily adaptable reaction vessel system for performing liquid handling operations, such as sampling, incubating, homogenizing and/or metering fluids, can be constructed in a modular fashion, comprising a first container, to which at least two second containers are connected, wherein the contents of said second containers can be transferred from one of said second containers into said first container and back, or into another second container.
US07722830B2
A system for decomposing a liquid or gaseous organic compound comprises a ultraviolet decomposition unit and an intermediate product treatment apparatus. The ultraviolet decomposition unit decomposes an organic compound contained in polluted liquid or polluted gas by irradiating ultraviolet rays whose wavelength is less than 300 nm to the polluted liquid or the polluted gas containing the organic compound. An acid electrolytic water feed pipe and an alkali electrolytic water feed pipe are respectively connected to the intermediate product treatment apparatus through valves to neutralize an intermediate product, which results from decomposition of the organic compound, for decomposition by selectively adding strong alkali electrolytic water and strong acid electrolytic water to the polluted liquid or the polluted gas containing the intermediate product.
US07722821B2
A sample cup for retaining a sample material to be subjected to an x-ray spectrochemical analysis. The sample cup comprises a cell body of a cylindrical configuration having an open top end and an open bottom end and defining a hollow between the two open ends, the open top end having an outer wall and an inner wall encircling the open top end. The outer wall and the inner wall extend axially and are positioned in concentric relationship with one another and form a reservoir space therebetween.
US07722801B2
The vacuum carburizing apparatus introduces a carburizing gas into a carburizing chamber to subject the treatment material to vacuum carburizing. The vacuum carburizing apparatus comprises a carburizing chamber that houses a treatment material therein, a vacuum pump that exhausts gas from the carburizing chamber inside to obtain vacuum, a carburizing gas supply unit that supplies carburizing gas into the carburizing chamber in pulse mode, a reflux pipe which connects an intake side of the vacuum pump and an exhaust side of the vacuum pump, an opening and closing valve which is provided on the way of the reflux pipe, and a control unit which opens the opening and closing valve when a supply of the carburizing gas into the carburizing chamber is started, wherein the control unit closes the opening and closing valve when the supply ends.
US07722793B2
The invention concerns a method of recuperating a turbine element constituted of a substrate, forming the body of the element, and a protective coating adhering to the substrate. The method comprises the control of the turbine element in order to pinpoint the zones having a bonding defect between the protective coating and the substrate, and the elimination of the bonding defects between the protective coating and the substrate. The bonding defects are eliminated by means of a laser beam directed onto each zone having a bonding defect in order to induce a localized melting of the protective coating and the underlying substrate and enable a sound bond, at the level of said zone, between the protective coating and the substrate after stopping the laser beam.
US07722790B2
An LC display comprises in order (a) a light source, (b) a transparent polymeric film bearing on the light exit surface of the film an array of close-packed convex microlenses having a distribution of sizes and oriented in one direction, whereby the light output is preferentially spread in a desired direction, and (c) an LC panel. A related process and film are also disclosed.
US07722773B2
A treatment method of organic compounds included in waste water, comprising the steps of: supplying waste water to an adsorber 2 filled with an adsorbent 3 therein for adsorbing the organic compounds in the waste water by the adsorbent 3 in the adsorber 2, supplying a current between an anode 9 and a cathode 8 in water including an electrolyte in an electrolyzer 6 for electrolyzing the water including an electrolyte, and supplying an electrolyte resulting from electrolysis in the electrolyzer 6 to the adsorbent 3 in the adsorber 2 for contacting the electrolyte with the adsorbent 3, so that the organic compounds adsorbed by the adsorbent 3 are desorbed or decomposed.
US07722768B2
The invention is directed to a process for the simultaneous removal of BOD and phosphate from a liquid containing ammonium, BOD, phosphate and magnesium, the method comprising: feeding the liquid to a reactor containing BOD-oxidising biomass; ensuring that the liquid in the reactor contains an excess to stoichiometry of ammonium and magnesium relative to phosphate, wherein the stoichiometry is related to the stoichiometry of struvite; oxidising at least part of the BOD; adjusting the pH of the liquid in the reactor at a desired value; forming solid material in the reactor, the solid material comprising struvite; separating at least part of the solid material from the reactor effluent; returning a part of the solid material to the reactor. The invention is also directed to a reactor for this process. The advantage of the process and the apparatus is that in one reactor both BOD and phosphate are removed from the liquid.
US07722764B2
A gradient pump apparatus which is capable of continuously and precisely feeding, to a chromatograph, eluents at intervals of certain time and at a constant flow rate in units of nano-liter per minute while the composition of two or more eluent components is changed. The gradient pump apparatus includes a 10-port valve for switching an eluent mixing pipe, in which a feed pressure of eluents changes with time, to be connected to a first loop which is supplied with another eluent from an isocratic pump that should function to hold an eluent feed pressure constant, and which is connected to an analytic section, or to a second loop through which the eluents are drained. A controller computes a difference between a value of the pressure in the eluent mixing pipe and a value of the eluent feed pressure applied from the isocratic pump when the eluent mixing pipe is connected to the second loop. At the time when the eluent mixing pipe is connected to the first loop with shift of the 10-port valve, the feed speed of the isocratic pump is determined based on the above pressure difference. The isocratic pump is controlled in sync with the valve shift so that the determined feed speed of the isocratic pump is obtained.
US07722746B1
A water treatment system includes a circulation pump and an electrolytic chamber in fluid communication with a main body of water. Electrolytic plates within the electrolytic chamber generate chlorine. When mineral deposits foul the electrolytic plates, water is isolated within the electrolytic chamber and a minimal amount of a pH-reducing agent is added to the electrolytic chamber to remove the mineral deposits. In a first embodiment, the pH-reducing agent is admitted on a periodic timed basis. In a second embodiment, the pH-reducing agent is added when the pH of the main body of water falls below a predetermined threshold. In both embodiments, cleaning is accomplished by adding the pH-reducing agent when the circulation pump is not operating so that the acid dwells within the electrolytic chamber for a sufficient amount of time. Activation of the circulation pump causes the pH-reducing agent to enter the main body of water.
US07722745B2
This invention relates generally to a method and apparatus for electroplating selected portions of elongate and generally cylindrical metallic articles pre assembled and held in spaced-apart fashion into a nonconductive support member encircled by a metallic tube like member one portion of article extending from one side of support member with the opposing portion of article extending from the opposing end of support member including a locating device to receive the articles so the portion of the articles to be electroplated extends downwardly. At least one plating cell is provided adjacent the lower region for contacting the downwardly extending portion of the articles with plating liquid whereas the plating liquid is ejected towards the articles including at least one conducting device for electric current is provided adjacent to the upper region for engaging with the portion of article extending upwardly whereas the electric current is being distributed to articles evenly and complete.
US07722733B2
A method for sterile connection of tubing includes welding the tubing sections together using an efficient laser. The ends of the tubing sections are brought together prior to the initiation of welding, facilitating isolation of interior passage of the tubing sections. The method can be carried out by an apparatus which is relatively inexpensive and compact.
US07722729B2
A method for repairing an article comprises providing an article, providing a repair material, and joining said repair material to said article. The repair material comprises, in atom percent, at least about 50% rhodium; up to about 49% of a first material, said first material comprising at least one of palladium, platinum, iridium, and combinations thereof; from about 1% to about 15% of a second material, said second material comprising at least one of tungsten, rhenium, and combinations thereof; and up to about 10% of a third material, said third material comprising at least one of ruthenium, chromium, and combinations thereof. The repair material comprises an A1-structured phase at temperatures greater than about 1000° C., in an amount of at least about 90% by volume.
US07722724B2
Method for processing a substrate are provided. The processing occurs when the substrate is moved between cluster tools. One method includes providing the substrate to a cluster tool, and the cluster tool is configured to move the substrate into a meniscus processing module having at least one proximity head. The proximity head is configured to perform operations including applying a fluid onto a region of a surface of the substrate, such the fluid is continuously flown so as to substantially fill the region between a surface of the proximity head and the surface of the substrate. An operation of removing the fluid from the region by applying a vacuum force through the proximity head is also provided. The applying and removing is operated substantially simultaneously so that the fluid forms a controlled fluid meniscus that remains between the surface of the substrate and the surface of the proximity head when the proximity head is positioned over the substrate. The method can include moving one of the controlled fluid meniscus or the substrate so that the controlled fluid meniscus is caused to contact regions of the surface of the substrate to cause fluid processing of the surface of the substrate when in the meniscus processing module. The method can also include moving the substrate out of the meniscus processing module and into a next module of the of the cluster tool or out of the cluster tool.
US07722713B2
Carbon blacks which are useful in a variety of polymer compounds including ABS compounds are described, as well as methods of making the carbon blacks and polymer compounds. The carbon blacks provide desirable jetness and impact strength, as well as good dispersion in a polymer.
US07722708B2
An indoor air purification apparatus and method includes a watertight chamber including a top portion having a water inlet, a first air portal, a second air portal, a bottom portion, and a plurality of shelves mounted between the top portion and the bottom portion. Water continuously flows from the water inlet at the top of the chamber, typically falling over the shelves to a reservoir. Typically, a water pump returns the water to the water inlet at the top portion of the chamber through at least one conduit leading from the reservoir. An air pump typically drives the room air through the chamber from one air portal to the other and back into the room. The room air is purified as it mixes with the water cascading over the shelves.
US07722703B2
The device has a honeycomb rotor which is rotated and which supports an adsorbant. A seal divides the honeycomb rotor into a desorption zone and at least one other zone including an adsorption zone. The seal has a heat resistant/non flammable portion and an elastic seal portion. The heat resistant portion has a slot cut in a surface which contacts the honeycomb rotor. The elastic seal portion is formed outside of the desorption zone with respect to the heat resistant portion. Desorption air is substantially completely sealed within the desorption zone. The seal may allow for hot (perhaps 300° C.) desorption gas to be used with a rotation type gas adsorption concentration device.
US07722700B2
Component gas is separated from a gas mixture. Component gas flow rate, or demand, is determined. One or more gas separator operating parameters is changed based on the component gas flow rate. For example, gas flow rate can be approximated by measuring a rate of pressure decay of a product tank during a time period in which the tank is not being replenished by the separating system. When it is determined that the flow rate is relatively low, operating parameters of the separating system are changed to improve system performance with the lower demand. For example, a target product tank pressure at which sieve beds are switched can be lowered when demand is lower.
US07722695B2
A neem based composition for coating nitrogenous fertilizer. The composition comprises 2-10 percent by weight neem extract, 10-60 percent by weight neem oil, 10-25 percent by weight binder and 25-50 percent by weight organic solvent. Also a method of making the composition by mixing the ingredients, a method of coating a nitrogenous fertilizer by mixing it with 0.5 to 1.0 percent by weight of the neem based composition and nitrogenous fertilizer coated with 0.5 to 1.0 percent by weight of the neem based composition.
US07722674B1
A linearly expanding spine cage has a minimized diameter in its unexpanded state that is equal to the diameter of an insertion groove cut into adjacent vertebral bodies. The cage conformably engages between the endplates of adjacent vertebrae to effectively distract the disc space, widen neuroforamina, stabilize the motion segments and eliminate pathologic spine motion. Angular deformities can be corrected, and natural curvatures maintained. The cage enhances spinal arthrodesis by creating a rigid spine segment. Expanding linearly (vertically, along the vertical axis of the adjacent spine) rather than uniformly, the cage height increases and holds the vertebrae with fixation forces greater than adjacent bone and soft tissue failure forces. Stability is thus achieved immediately, enabling patient function by eliminating painful motion. The cage width remains stable, so as to decrease impingement upon a second cage, or upon soft tissue structures in the immediate vicinity, including neural or vascular elements.
US07722666B2
A cardiac valve with a first anchor frame and a cover on the first anchor frame for unidirectional flow of a liquid through the valve.
US07722659B2
An endoluminal prosthesis, comprising a tubular body, said tubular body developing along a longitudinal axis, said tubular body comprising a plurality of serpentines, which develop along a substantially circumferential direction, each of said serpentines comprising arm portions of a preset width transversal to their main longitudinal extension, and bend portions joining two subsequent arms, at least one bridge, having a main longitudinal extension, connecting two adjacent serpentines, wherein the bends facing an adjacent serpentine are circumferentially staggered relative to the opposite bends of the adjoining serpentine, both when the prosthesis is collapsed and when the prosthesis is expanded or partially expanded, wherein the at least one bridge connecting adjacent serpentines extends substantially straight, and wherein the at least one bridge has a width transversal to its main longitudinal direction of a greater value than the arm width.
US07722656B1
The current invention includes a device and method for the promotion and stimulation of hair growth using one or more light sources such as a diode laser, each light source operating in the infrared range at wavelengths in a range from about 2500 nm to about 10,000 nm and at a low wattage, collectively less than about 1000 mw, with the power level typically being in the region of 500 mw. A diode laser operating in this range will have a greater dispersion rate than heretofore, thus requiring fewer diodes to cover the same area of scalp with less power required per diode laser.
US07722648B2
An apparatus comprises a pair of bone attachment devices and a crosslink device for a spinal fixation system or other implant arrangement. The bone attachment devices include a head with socket to receive a spinal rod or other elongate element and the crosslink device includes a pair of bridging members each having an end section for connecting with the bone attachment devices. An interconnection device situated between the bridging members receives the bridging members and allows translational and rotational freedom therebetween while being operable to secure the bridging members in position relative to one another. A pair of engaging members are structured to engage the head of the respective bone attachment device and bear against the respective adjacent end of crosslink device to lock the crosslink and the bone attachment device in a rigid construct are also included.
US07722643B2
Tissue connector assemblies having at least two piercing members, each releaseably coupled to a surgical fastener such as a surgical clip. A flexible member such as a suture may be used to couple one or both piercing members to respective ends of the fastener.
US07722642B2
Wire fasteners having legs with lengths that can be one hundred times the width of the fastener are used to secure items, such as prosthesis valves to a patient during minimally invasive surgery. The fasteners are manipulated into position and then are immobilized by means of the legs thereof for tensioning, cutting and forming in situ. The fasteners are manipulated, tensioned and formed from the leg end of the fasteners. Tools for initially placing the fasteners and for immobilizing, tensioning, cutting and bending the fastener legs are disclosed. Once the fasteners are initially placed, the prosthesis is placed on the long legs of the placed fasteners and is guided into position on the legs. Once the prosthesis is in position, the legs of the fasteners are immobilized, tensioned, cut and bent into staple-like shapes to secure the prosthesis to the patient. A method for carrying out the procedure using the long fastener is also disclosed. Using the teaching of the present disclosure, a surgeon can customize a fastener to the particular surgery or even to the particular portion of surgery being performed during the surgery.
US07722640B2
A surgical grasping instrument for grasping an elongated implement, which comprises a frame; an elongated member connected to the frame and extending distally therefrom, the elongated member defining a longitudinal axis; and a pair of jaw members operatively connected to the elongated member, the jaw members being adapted for movement between an open position and a closed position, at least one of the jaw members having a recess defined therein and arranged about a central recess axis extending at an angle of about 35° or less relative to the longitudinal axis of the elongated member, wherein upon movement of the jaw members to the closed position, the jaw members form a holding groove that can engage and firmly secure the elongated implement.
US07722637B2
An embolic coil deployment system for placing a coil at a preselected site within a vessel of the human body. The deployment system includes a heating element at the distal end of a delivery member and a heat responsive coupling for holding the coil during positioning of the coil and the heating element is heated to reduce the strength of the heat responsive coupling for releasing the coil at a desired position within the vessel.
US07722635B2
A compact blood clot filter having an alignment section that overlaps with a filter section in an axial direction is formed from a single tube without any welding points to provide high structural integrity, low profile and low manufacturing cost. The filter section has filter struts that extend radially and longitudinally from a hub. The alignment section has alignment struts in which the downstream end of each alignment strut forms a junction with the downstream end of an adjacent alignment strut while the upstream end of each alignment strut forms a junction with the upstream end of an adjacent alignment strut and with one of the filter struts to ensure symmetrical deployment of the filter struts and provide stable centering of the filter section.
US07722630B1
An apparatus and method for passing a suture through tissue includes a first jaw member having a retaining structure to support a portion of the suture proximate a first surface of the tissue. A second jaw member is associated with the first jaw member. The second jaw member is selectively configurable in a first configuration to perform a first stitch or in a second configuration to perform a second stitch.
US07722626B2
The invention provides a method of using an apparatus for manipulating matter in a confined or inaccessible space, comprising providing an apparatus having manipulator means at least partly constructed of one or more bent or twisted elongate shape memory alloy members having pseudoelasticity at the intended manipulation temperature, and a hollow housing or cannula capable of holding at least the shape memory alloy member(s) in a relatively straightened state, and actuating means for extending the shape memory alloy member(s) from the housing to manipulate matter within the space and for withdrawing the shape memory alloy member(s) into the housing, the arrangement being such that the shape-memory alloy member(s) bend(s) or twist(s) pseudoelastically in a lateral or helical sense to manipulate the matter on extending from the housing at the manipulation temperature, and become(s) relatively straightened on withdrawal into the housing at the temperature.
US07722625B2
A modular bone clamp instrument includes a first elongated arm with a first clamping surface and a second elongated arm with a second clamping surface. A ratchet mechanism is provided between the first elongated arm and the second elongated arm. The ratchet mechanism allows the first elongated arm to move in a first direction, but prevents movement of the first elongated arm in an opposite direction. A squeeze handle is connected to the second elongated arm. The squeeze handle includes a forward handle member and a rear handle member. The rear handle member includes a head with an open chamber. The second elongated arm includes a shoulder that fits in the open chamber. A retention pin extends through the head and shoulder to secure the handle to the second elongated arm. Rotation of the retention pin allows the handle to be released from the second elongated arm.
US07722612B2
An intravertebral widening device (4) extends from a proximal end (8) to a distal end (10) along an extension axis (X), said distal end (10) having an elastically deformable element (56) suitable to pass from a relaxed configuration for placing the distal end (10) within a vertebral body (6) to a deformed configuration for forming a cavity within said vertebral body (6). The elastically deformable element (56) comprises at least one tab (60) having, along the longitudinal extension thereof, a varying thickness relative to a radial direction incident with said extension axis (X) and contained in a perpendicular plane to said extension axis (X), such as to vary the stiffness of at least one tab (60) along the extension thereof.
US07722611B2
A method of clavicle fracture fixation includes using a K-wire to create a pilot hole extending longitudinally through the medullary canal of the lateral and medial fragments of the fractured clavicle while the fragments are reduced, enlarging a medial portion of the pilot hole in the lateral fragment and a lateral portion of the pilot hole in the medial fragment, wherein such enlarged portions are together sized for receiving the clavicle nail, attaching the lateral end of the clavicle nail to the K-wire, manipulating the K-wire such that substantially the entire length of the clavicle nail is positioned inside of the lateral fragment, aligning the lateral and medial fragments longitudinally, and manipulating the K-wire such that approximately half of the length of the clavicle nail is positioned within the medial fragment and approximately half of the nail is positioned within the lateral fragment.
US07722609B2
An outrigger having a locking mechanism includes an elongated member having a distal end, a proximal end, and a threaded portion proximate the distal end; a moveable member operably associated with the elongated member; and a slide lock operably associated with the moveable member. The thread portion may have at least one flat side and the slide lock may have at least one flat portion. The at least one flat side and the at least one flat portion may engage such that the slide lock translates along, but not rotate about, the threaded portion. The slide lock may engage a surface of the clamp. The moveable member may move the slide lock towards the clamp such that the engagement portion engages the surface of the clamp. The connection between the engagement portion and the surface of the clamp may prevent the slide lock from rotating relative to the clamp.
US07722601B2
A method and system are disclosed enabling configuration of a control system for an electrosurgical generator system for creating new surgical applications without changing the underlying software system. The system includes an outer loop controller for generating a control signal in accordance with at least a first subset of sensor data from at least one sensor; an inner loop controller for generating a setpoint control signal which is provided to an RF stage in accordance with at least the control signal generated by the outer loop controller and a second subset of sensor data from the at least one sensor; and a configuration controller for generating configuration data and providing first and second configuration data sets of the configuration data to the inner loop and outer loop controllers, respectively, for configuration thereof to provide a type of control selectable from a variety of types of control.
US07722600B2
A system and method for using a light source to treat tissue with NIR light. The operation provides for generating higher temperatures in deeper layers of tissue relative to shallower layers of tissue. The increased temperature in dermal layers can operate to induce collagen shrinkage, or remodeling. One of the light sources for providing a broad spectrum of NIR light is a filament light. The light from the filament lamp can be selectively filtered, and after filtering this light is applied to the skin, where the selective filtering can enhance the ability to elevate the temperature of deeper layers of tissue, relative to layers of tissue which are closer to the surface of the skin.
US07722598B2
A medical delivery system for delivering a fluid to a desired location within a body that includes a first member having an aperture, and a second member adapted to be positioned over the first member. The fluid to be delivered is contained within a fluid storage device, formed by at least one of the first member and the second member. The medical delivery system includes means for repositioning the first member relative to the second member between a first state preventing passage of the fluid through the aperture and a second state enabling passage of the fluid outward from the fluid storage device through the aperture.