US07902586B2
A non-volatile memory device 100 contains: an insulating substrate 10; a first electrode 20 provided on the insulating substrate 10; a second electrode 30 provided on the insulating substrate 10; and a gap 40 set between the first electrode 20 and the second electrode 30, in which a distance G between the first electrode 20 and the second electrode 30 is: 0 nm
US07902579B2
A magnetic memory device includes a memory region, an input and a sensor. The memory region includes a free layer, a pinned layer and a non-magnetic layer. The free layer has adjacent sectors and a magnetic domain wall. The pinned layer corresponds to the sectors and has a fixed magnetization direction. The non-magnetic layer is formed between the free layer and the pinned layer. The memory region includes a magnetic domain wall stopper for stopping the magnetic domain wall formed at each boundary of the sectors. The input is electrically connected to one end of the free layer for inputting a signal for magnetic domain dragging. The sensor measures a current flowing through the memory region.
US07902578B2
A solid-state imaging device including an imaging area formed of a plurality of pixels arrayed in a two-dimensional matrix is provided. The solid-state imaging device includes: a photoelectric conversion portion including a charge accumulation region provided on a semiconductor substrate; a read transistor for reading electric charges from the photoelectric conversion portion; and a gettering site for separating metal impurities within the semiconductor substrate from at least the photoelectric conversion portion. The photoelectric conversion portion is provided on the surface side of the semiconductor substrate, and the gettering site is provided on the rear side away from the semiconductor substrate.
US07902575B2
The invention relates to a field-effect microelectronic device, as well as the method of production thereof. The device includes a substrate as well as at least one improved structure capable of forming one or more transistor channels. This structure, formed by a plurality of bars stacked on the substrate, can make it possible to save space in the integration of field-effect transistors as well as to improve the performance thereof.
US07902574B2
This invention provides a type of solid-state image pickup device characterized by the fact that for a solid-state image pickup device with a broad dynamic range, it is possible to suppress the dark current than photoelectrons overflowing from the photodiode, as well as its driving method. Plural pixels are integrated in an array configuration on a semiconductor substrate. Each pixel has the following parts: photodiode (CPD), transfer transistor (φT), floating diffusion (CFD), accumulating capacitive element (CS), accumulating transistor (φS), and a reset transistor. During the accumulating period of photoelectric charge, voltage (α) over that applied on the semiconductor substrate, or −0.6 V or lower than the voltage applied on the semiconductor substrate, is applied as an OFF potential on the gate electrode of at least one transfer transistor, the accumulating transistor and the reset transistor.
US07902570B2
A single-photon detector is disclosed that provides reduced afterpulsing without some of the disadvantages for doing so in the prior art. An embodiment of the present invention provides a stimulus pulse to the active area of an avalanche photodetector to stimulate charges that are trapped in energy trap states to detrap. In some embodiments of the present invention, the stimulus pulse is a thermal pulse.
US07902569B2
Some disclosed interband tunneling diodes comprise a plurality of substantially coherently strained layers including layers selected from a group consisting of silicon, germanium, and alloys of silicon and germanium, wherein at least one of said substantially coherently strained layers is tensile strained. Some disclosed resonant interband tunneling diodes comprise a plurality of substantially coherently strained layers including layers selected from a group consisting of silicon, germanium, and alloys of silicon and germanium, wherein at least one of said substantially coherently strained layers defines a barrier to non-resonant tunnel current. Some disclosed interband tunneling diodes comprise a plurality of substantially coherently strained layers, wherein at least one of said substantially coherently strained layers is tensile strained. Some disclosed resonant interband tunneling diodes comprise a plurality of substantially coherently strained layers, wherein at least one of said substantially coherently strained layers defines a barrier to non-resonant tunnel current.
US07902561B2
The present invention relates to a nitride semiconductor light emitting device including: a first nitride semiconductor layer having a super lattice structure of AlGaN/n-GaN or AlGaN/GaN/n-GaN; an active layer formed on the first nitride semiconductor layer to emit light; a second nitride semiconductor layer formed on the active layer; and a third nitride semiconductor layer formed on the second nitride semiconductor layer. According to the present invention, the crystallinity of the active layer is enhanced, and optical power and reliability are also enhanced.
US07902560B2
A uniform high brightness light source is provided using a plurality of light emitting diode (LED) chips with slightly different pump wavelengths with a wavelength converting element that includes at least two different wavelength converting materials that convert the light to different colors of light. The intensity of the light produced by the LED chips may be varied to provide a tunable CCT white point. The wavelength converting element may be, e.g., a stack or mixture of phosphor or luminescent ceramics. Moreover, the manufacturing process of the light source is simplified because the LED chips are all manufactured using the same technology eliminating the need to manufacture different types of chips.
US07902558B2
A method for manufacturing a substrate of a liquid crystal display device is disclosed. The method includes forming a conductive line structure with low resistance to improve the difficulty of the resistance matching. The method can effectively reduce the resistance of the conductive line of the LCD panel to increase the transmission rate of the driving signal. Hence, the increasing yield of products can reduce the cost of manufacturing, and can meet the requirement of the large-size and high-definition thin film transistor liquid crystal display device.
US07902555B2
A hetero semiconductor corner region, which is a current-concentration relief region that keeps a reverse bias current from concentrating on the convex corner, is arranged in a hetero semiconductor region. Thereby, a current concentration on the convex corner can be prevented. As a result, an interrupting performance can be improved at the time of interruption, and at the same time, the generation of the hot spot where in a specific portion is prevented at the time of conduction to suppress deterioration in a specific portion, thereby ensuring a long-term reliability. Further, when the semiconductor chip is used in an L load circuit or the like, for example, at the time of conduction or during a transient response time to the interrupted state, in an index such as a short resistant load amount and an avalanche resistant amount, which are indexes of a breakdown tolerance when overcurrent or overvoltage occurs, the current concentration on a specific portion can be prevented, and thus, these breakdown tolerances can also be improved.
US07902554B2
A method of forming a polysilicon film having smooth surface using a lateral growth and a step-and-repeat laser process. Amorphous silicon formed in a first irradiation region of a substrate is crystallized to form a first polysilicon region by a first laser shot. Then, the substrate is moved a predetermined distance, and irradiated by a second laser shot. The polysilicon region is then recrystallized and locally planarized by subsequent laser shots. After multiple repetitions of the irradiation procedure, the amorphous silicon film formed on a substrate is completely transformed into a polysilicon film. The polysilicon film includes lateral growth crystal grains and nano-trenches formed in parallel on the surface of the polysilicon film. A longitudinal direction of the nano-trenches is substantially perpendicular to a lateral growth direction of the crystal grains.
US07902545B2
A gallium-nitride semiconductor apparatus may include an active region having one or more nitride-based barrier layers that are modulation-doped using a nitride-based doped layer. An active region may have at least two nitride-based barrier layers, and a nitride-based blocking layer may be disposed between the at least two barrier layers.
US07902541B2
A semiconductor nanowire having two semiconductor pads on both ends is suspended over a substrate. Stress-generating liner portions are formed over the two semiconductor pads, while a middle portion of the semiconductor nanowire is exposed. A gate dielectric and a gate electrode are formed over the middle portion of the semiconductor nanowire while the semiconductor nanowire is under longitudinal stress due to the stress-generating liner portions. The middle portion of the semiconductor nanowire is under a built-in inherent longitudinal stress after removal of the stress-generating liners because the formation of the gate dielectric and the gate electrode locks in the strained state of the semiconductor nanowire. Source and drain regions are formed in the semiconductor pads to provide a semiconductor nanowire transistor. A middle-of-line (MOL) dielectric layer may be formed directly on the source and drain pads.
US07902540B2
A lateral p-i-n photodetector is provided that includes an array of vertical semiconductor nanowires of a first conductivity type that are grown over a semiconductor substrate also of the first conductivity type. Each vertically grown semiconductor nanowires of the first conductivity type is surrounded by a thick epitaxial intrinsic semiconductor film. The gap between the now formed vertically grown semiconductor nanowires-intrinsic semiconductor film columns (comprised of the semiconductor nanowire core surrounded by intrinsic semiconductor film) is then filled by forming an epitaxial semiconductor material of a second conductivity type which is different from the first conductivity type. In a preferred embodiment, the vertically grown semiconductor nanowires of the first conductivity type are n+ silicon nanowires, the intrinsic epitaxial semiconductor layer is comprised of intrinsic epitaxial silicon, and the epitaxial semiconductor material of the second conductivity type is comprised of p+ silicon.
US07902529B2
An electron source can selectively provide a first stream of electrons that travels in a direction along an imaginary line to a location remote from the electron source, or a second stream of electrons that travels in the direction along the line to the location. The electron source includes a first electron emitter for selectively emitting electrons for the first stream, and a second electron emitter for selectively emitting electrons for the second stream. A different aspect relates to a method for operating an apparatus having an electron source that includes first and second electron emitters. The method includes selectively producing a first stream of electrons that travels from the first electron emitter in a direction along an imaginary line to a location remote from the electron source, or a second stream of electrons that travels from the second electron emitter in the direction along the line to the location.
US07902521B2
The present invention relates to a method for improving focusing in an electron column that generates an electron beam. The method for controlling the focusing of an electron beam in according to the present invention reduces the spot size of the electron beam when the electron beam reaches a specimen, so that resolution can be increased and the line width of a pattern in a semiconductor lithography process can be reduced, with the result that the performance of the electron can be improved.
US07902520B2
A method of operating an electronic device including determining an initial charge level at a non-volatile charge storage structure of a radiation-sensitive device including a radiation-reactive material and determining if a first radiation event has occurred based upon the non-volatile charge storage device having a different charge level than the initial charge level. The method further includes identifying the first radiation event as associated with either a first type of radiation or a second type of radiation based upon the different charge level.
US07902514B2
An image detecting device (radiation solid-state detecting device) including an image detector (sensor substrate) for recording an image and outputting the recorded image as image information; a temperature regulation control unit for performing a temperature regulation control operation to adjust the image detector to a predetermined temperature; and an image information output detecting unit (timing control signal detector) for detecting the output of the image information from the image detector, and outputting the detected output as an image information output detection signal to the temperature regulation control unit, wherein the temperature regulation control unit halts the temperature regulation control operation on the image detector based on the image information output detection signal that is input thereto.
US07902505B2
When a sample includes repeated cells, a scale pattern corresponding to the repeated cells is generated. Next, the scale pattern generated is superimposed on the image of the repeated cells of the sample, thereby identifying a destination cell. Moreover, disposition of the repeated cells of the sample is determined based on positions of at least three ends of the repeated cells. Then, the position of the destination cell is identified from this disposition of the repeated cells. Furthermore, a zoom image is generated by a combination of a zoom based on beam deflection function and a zoom based on software. Then, the image shift is performed by software without displacing a sample stage.
US07902496B2
Methods for density logging utilizes gamma-rays above a pair-production threshold so as to determine lithology information of formations whereby to correct a measured density data.
US07902489B2
A control actuator system. The novel system includes a control surface mounted on a body and adapted to move in a first direction relative to the body, and a first mechanism for storing energy as the control surface moves in the first direction and releasing the stored energy to move the control surface in a second direction opposite the first direction. In an illustrative embodiment, the system is adapted to rotate an aerodynamic control surface of a rolling missile, and the first mechanism is a torsional spring arranged such that rotating the control surface in the first direction winds up the spring and releasing the spring causes the control surface to oscillate back and forth, alternating between the first and second directions. In a preferred embodiment, the spring has a spring constant such that the control surface oscillates at a natural frequency matching a roll rate of the missile.
US07902488B2
An instrument and associated method are disclosed for the accelerated synthesis of peptides by the solid phase method. The instrument includes a microwave cavity, a microwave source in communication with the cavity, a column in the cavity formed of a material that is transparent to microwave radiation, a solid phase peptide support resin in the column, respective filters for maintaining the solid phase support resin in the column, a first passageway for adding starting compositions to the column, a second passageway for removing compositions from the column, and a third passageway for circulating compositions from the column into the third passageway and back to the column.
US07902485B2
Temperature setting of a thermal plate is performed so that the line width of a resist pattern is uniformly formed within a wafer. The thermal plate of a PEB unit is divided into a plurality of thermal plate regions so that the temperature can be set for each of the thermal plate regions. A temperature correction value for adjusting the temperature within the wafer mounted on the thermal plate is set for each of the thermal plate regions of the thermal plate. The temperature correction value for each of the thermal plate regions of the thermal plate is set after calculation by a calculation model created from a correlation between a line width of the resist pattern formed by thermal processing on the thermal plate and the temperature correction value. The calculation model M calculates the temperature correction value to make the line width uniform within the wafer, based on a line width measured value of the resist pattern.
US07902477B1
A test work station for testing ICs includes an output bench with sliding rails that partitions the table top of the output bench into segregated areas. ICs that pass testing are sorted according to an operating parameter, in other words binned, and placed in the appropriate segregated area. The sliding rails avoid mingling of the various categories (bins) of ICs. In a further embodiment, the test work station includes an input bench for receiving product. Failed ICs are kept on the input bench, thus segregating them from ICs that have passed testing and avoiding inadvertent mixing of bad ICs with good ICs. In a particular embodiment, the input and output benches are at a height that allows an operator to stand while working, and allows storage underneath the benches to keep the work areas clear.
US07902476B2
An ignition switch assembly connectable to a rotary shaft of a gas tap of a cooking device. The ignition switch assembly has a coupling element connectable to the rotary shaft of the gas tap, a fixed contact, a mobile contact, and a cam coupled to the coupling element which is configured to move the mobile contact relative to the fixed contact. The cam has a guide that is moveable within a groove of the switch assembly which controls the lateral displacement of the cam in relation to the coupling element so that the lateral displacement of the cam is controlled such that when the coupling element is rotated in a first direction, electrical contact between the mobile and fixed contacts is achievable, but when the coupling element is rotated in a second direction opposite the first direction the lateral displacement of the cam is controlled to prevent electrical contact between the mobile and fixed contacts.
US07902470B2
Disclosed is a decorative key sheet of high visibility which is superior in terms of design and helps to maintain a quality appearance, which enables an operator to perform input operation safely, and which is of a thin type. The decorative key sheet is formed as a thin sheet including an operation plate, a film sheet, and a base sheet. A fine asperity pattern is provided on a front surface side of an operation plate. Further, a light reflection layer enhancing the visibility of the fine asperity pattern is provided on a back surface of the operation plate. The operation plate is transparent. The fine asperity pattern is formed on a resin layer.
US07902463B2
A printed wiring board includes an insulation layer having a surface, electrodes embedded in the insulation layer, a resistor formed on the surface of the insulation layer and electrically connected to the electrodes, and an external connection conductive pattern formed over the surface of the insulation layer and electrically connected to one or more electrodes. The insulation layer and the electrodes form a component-mounting surface on the surface of the insulation layer, the component-mounting surface is substantially leveled with the surface of the insulation layer and includes a resistor forming region on which the resistor is formed, and the external connection conductive pattern is separated by a space from the resistor.
US07902455B2
Provided is a lighting arrester capable of preventing damage caused by a lightning by discharging charges charged by approach of a thundercloud. The lightning arrester includes: a conductive rod installed at an upper part of an object to be protected from a lightning and connected to a ground part; a charge pipe having a cylindrical shape, formed of an insulating body to be insulated from the rod, and electrically charged with charges having a polarity opposite to ground charges; and a plurality of charge pins disposed on the charge pipe such that space charges in the air are charged to the pins by a thundercloud.
US07902441B2
Tumor suppressor genes play a major role in the pathogenesis of human lung cancer and other cancers. Cytogenetic and allelotyping studies of fresh tumor and tumor-derived cell lines showed that cytogenetic changes and allele loss on the short arm of chromosome 3 (3p) are most frequently involved in about 90% of small cell lung cancers and greater than 50% of non-small cell lung cancers. A group of recessive oncogenes, Fus1, 101F6, Gene 21 (NPRL2), Gene 26 (CACNA2D2), Luca 1 (HYAL1), Luca 2 (HYAL2), PL6, 123F2 (RaSSFI), SEM A3 and Beta* (BLU), as defined by homozygous deletions in lung cancers, have been located and isolated at 3p21.3.
US07902437B1
A novel maize variety designated PHWMK and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PHWMK with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PHWMK through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PHWMK or a trait conversion of PHWMK with another maize variety. Inbred maize varieties derived from maize variety PHWMK, methods for producing other inbred maize varieties derived from maize variety PHWMK and the inbred maize varieties and their parts derived by the use of those methods.
US07902419B2
An alkylation process comprising contacting a first hydrocarbon feed comprising at least one olefin having from 2 to 6 carbon atoms and a second hydrocarbon feed comprising at least one isoparaffin having from 3 to 6 carbon atoms with a halide-based acidic ionic liquid catalyst under alkylation conditions to produce an alkylate containing an organic halide and contacting at least a portion of the alkylate with a hydrotreating catalyst in the presence of hydrogen under hydrotreating conditions to reduce the concentration of the organic halide in the alkylate is disclosed.
US07902417B2
A method of converting at least one first alkane to a mixture of at least one low molecular weight alkane (optionally also including additional lower and/or higher molecular weight alkanes) and at least one high molecular weight alkane, comprising: reacting a first alkane in the presence of dual catalyst system comprising a first catalyst (i.e., a hydrogen transfer catalyst and preferably an iridium pincer complex catalyst) and a second catalyst (i.e., a metathesis catalyst) to produce a mixture of low and high molecular weight alkanes.
US07902415B2
A process for dimerizing alpha olefins comprising contacting (i) an alpha olefin having at least 3 carbon atoms, (ii) a hexadentate bimetallic catalyst, and (iii) a cocatalyst, and dimerizing the alpha olefin in a reaction zone at conditions effective to dimerize an alpha olefin to form a reaction zone effluent comprising alpha olefin oligomers including alpha olefin dimers. A process for dimerizing olefins comprising contacting (i) an alpha olefin having at least 3 carbon atoms, (ii) a hexadentate bimetallic complex comprising a cobalt compound, and (iii) a cocatalyst, and dimerizing the alpha olefin in a reaction zone at conditions effective to dimerize an alpha olefin to form a reaction zone effluent comprising oligomers including dimmers, wherein greater than 20 weight percent of the alpha olefin has been converted to oligomers, greater than 30 weight percent of the oligomers are dimers, and greater than 85 mole percent of the dimers are linear.
US07902413B2
This invention relates to a process for the aromatization of C6 to C12 alkanes, such as hexane, heptane and octane, to aromatics, such as benzene, ethyl benzene, toluene and xylenes, with a germanium-containing zeolite catalyst. The catalyst is a non-acidic aluminum-silicon-germanium zeolite on which a noble metal, such as platinum, has been deposited. The zeolite structure may be of MFI, BEA, MOR, LTL or MTT. The zeolite is made non-acidic by being base-exchanged with an alkali metal or alkaline earth metal, such as cesium, potassium, sodium, rubidium, barium, calcium, magnesium and mixtures thereof, to reduce acidity. The catalyst is sulfur tolerant and may be pretreated with a sulfur compound, i.e., sulfided. The hydrocarbon feed may contain sulfur up to 1000 ppm. The present invention could be applicable to a feedstream which is predominantly paraffinic and/or low in naphthenes. Lowering the hydrogen to hydrocarbon ratio increases conversion and aromatics selectivity.
US07902408B2
The present disclosure enables phenol recovery, purification and recycle in a simple, economic manner from waste streams from, for example, a phenol/acetone production process, e.g., a phenol/acetone plant or an upstream cumene hydroperoxide cleavage process step, and BPA production step, for use in the reaction with acetone to produce BPA. The disclosure therefore reduces the overall consumption of phenol in the production of BPA.
US07902405B2
2,6-Dimethyl-1-naphthaldehyde having a ratio of the amount of 3,7-dimethyl-1-naphthaldehyde to the total amount of 2,6-dimethyl-1-naphthaldehyde and 3,7-dimethyl-1-naphthaldehyde of 30 mol % or less is particularly useful as optical functional materials, etc. The present invention provides a process for producing such 2,6-dimethyl-1-naphthaldehyde in an industrially advantageous manner. Specifically, in the process for producing 2,6-dimethyl-1-naphthaldehyde through formylation of 2,6-dimethylnaphthalene with carbon monoxide, formylation is performed in the presence of hydrogen fluoride in an amount of 5 to 100 times by mole and boron trifluoride in an amount of 0.5 to 3.5 times by mole, with respect to 2,6-dimethylnaphthalene, and at a reaction temperature of 35 to 70° C.
US07902398B2
An apparatus and method for carbonylating a reactant, including sequestering Group VIII catalyst metal from a process stream which generally has a ppb concentration of the catalyst metal. The process stream is treated with a polymer having nitrogen-containing heterocyclic repeat units to sequester the catalyst from the stream, thus allowing valuable catalyst to be recovered and returned to the reaction mixture. An apparatus provides a resin bed downstream of the light ends column in a carbonylation process. Preferably, spent resin is regenerated with a regenerant composition compatible with the carbonylation reaction mixture so that catalyst metal can be directly recycled and the resin re-used.
US07902395B2
Disclosed is a process and apparatus for treating a purge stream in a carboxylic acid production process. The process employs a purge process that allows for the separation of oxidation byproducts into benzoic acid and non-benzoic acid oxidation byproducts, thus providing flexibility in the treatment and use of such oxidation byproducts.
US07902385B2
Novel ester compounds having formulae (1) to (4) wherein A1 is a polymerizable functional group having a carbon-carbon double bond, A2 is oxygen, methylene or ethylene, R1 is a monovalent hydrocarbon group, R2 is H or a monovalent hydrocarbon group, any pair of R1 and/or R2 may form an aliphatic hydrocarbon ring, R3 is a monovalent hydrocarbon group, and n is 0 to 6 are polymerizable into polymers. Resist compositions comprising the polymers as a base resin are thermally stable and sensitive to high-energy radiation, have excellent sensitivity and resolution, and lend themselves to micropatterning with electron beam or deep-UV.
US07902384B2
The present invention relates to compounds having estrogenic activity selected from the group consisting of Loliolide, (4S,6S)-4-Hydroxy-6-nonadecyl-tetrahydro-pyran-2-one, (4R,6S)-4-Hydroxy-6-nonadecyl-tetrahydro-pyran-2-one and analogues thereof. The compounds of the present invention are selective estrogen receptor modulator, which can selectively activate ERβ and simultaneously express high estrogenic activity, and also can be applied as medical or food compositions to improve estrogen deficiency-related symptoms.
US07902381B2
The invention relates to preparing derivatives of formula (1), wherein, in particular R1 and R2, identical or different, represent a hydrogen, flourine or chlorine atom, a hydroxy group, an alkyl radical and an alkoxy radical, R3 is an alkyl radical, a hydroxy group, or a methoxy radical, R4 is a hydrogen atom or a methyl radical and R5 and R6, identical or different, represent a hydrogen atom, an alkyl radical, an alkoxy radical, an alkylthio radical, and an alkylamino radical. The inventive method consists in reducing an amid of formula (9).
US07902379B2
The present invention relates to novel 1,3-dihydroindol-2-one (oxindole) derivatives of the formula (I) in which A, R3, R4, R5 R6 and R7 are defined according to claim 1, and to medicaments containing them for the treatment of diseases. In particular, the novel oxindole derivatives can be used for the control and/or prophylaxis of various vasopressin-dependent or oxytocin-dependent diseases.
US07902377B2
The invention provides an improved, highly efficient method for preparing Medetomidine, and its salts, in particular its pharmaceutically acceptable salts. The method utilizes the high reactivity of halogenated imidazoles towards transmetalation with Grignard reagents and the subsequent reaction with 2,3-dimethylbenzaldehyde.
US07902372B2
A compound of the formula (I) wherein the variables X1, X2, B, D, R1 to R7 including R3′, p, y, q, and z, are as defined or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for the treatment, prevention or amelioration of obesity and Related Diseases is disclosed.
US07902362B2
The invention is directed to a compound having the general formula (1): wherein each of La and Lb is an independently selected from a linking moiety comprising 0 to 10 main chain atoms, optionally substituted; each of Za and Zb is an independently selected complexing moiety comprising at least one nitrogen atom; either both or one of Za and/or Zb is coordinatively bonded to a respective transition metal complex Ma Va and Mb Vb through said nitrogen atom, wherein each of Ma and Mb is an independently selected transition metal, and each of Va and Vb is an independently selected valence group.
US07902361B2
The present invention relates to compounds of formula I, or pharmaceutically acceptable salts thereof, wherein R1 and R5 are each independently H, C(ORj′) or a hydrocarbyl group optionally substituted by one or more R6 groups; R2, R3, and R4 are each independently H, alkyl or alkenyl, each of which may be optionally substituted with one or more R7 groups; R6 and R7 are each independently halogen, NO2, CN, (CH2)mORa, O(CH2)nORb, (CH2)pNRcRd, CF3, COORe, CONRfRg, CORh, SO3H, SO2Ri, SO2NRjRk, (CH2)qNRa′CORg′, Rf′, (CH2)rNRb′SO2Rh′, SO2NRd′Ri′, SO2NRe′(CH2)sORc′, heterocycloalkyl or heteroaryl, wherein said heterocycloalkyl and heteroaryl may be optionally substituted by one or more substituents selected from aralkyl, sulfonyl, Rm and CORn; Rg′, Rh′, Ri′ and Rj′ are each independently selected from alkyl, aryl, aralkyl and heteroaryl, each of which may be optionally substituted with one or more substituents selected from halogen, OH, NO2, NH2 CF3 and COOH; m, p, q and r are each independently 0, 1, 2 or 3; n and s are each independently 1, 2, or 3; and Ra-n and Ra′-f′ are each independently H or alkyl. Further aspects of the invention relate to pharmaceutical compositions comprising such compounds, and their use in the preparation of a medicament for treating one or more of the following: a proliferative disorder, a viral disorder, a CNS disorder, a stroke, alopecia and diabetes.
US07902359B2
This invention relates to a compound of the following formula: wherein R1, R2, R3, G, and Z are defined herein. It also relates to is methods of treating autoimmune disease, cancer, and atherosclerosis with such a compound.
US07902352B2
Disclosed herein are sequences, molecules and methods used to suppress the expression of HD genes encoding for huntingtin protein in primates including Macaca mulatta and Homo sapiens. These sequences, molecules and methods aid in the study of the pathogenesis of HD and can also provide a treatment for this disease by reducing HD mRNA without causing death, locomotor impairment or cellular alterations of the Macaca mulatta and Homo sapiens.
US07902351B2
The invention provides methods, compositions, and kits comprising small interfering RNA (shRNA or siRNA) that are useful for inhibition of viral-mediated gene expression. Small interfering RNAs as described herein can be used in methods of treatment of HCV infection. ShRNA and siRNA constructs targetING the internal ribosome entry site (IRES) sequence of HCV are described.
US07902350B2
The present invention relates to Mycobacterium avium subspecies paratuberculosis (MAP) as the etiological agent of IBD, including ulcerative colitis and Crohn's disease, as well as Multiple Sclerosis and Alzheimer's Disease. As such, methods for monitoring efficacy of a anti-MAP therapy and determining whether a blood sample is suitable for transfusion are provided based upon presence, absence or amount of MAP nucleic acid.
US07902349B2
Purified nucleic acids comprising a nucleotide sequence encoding an immunogenic polypeptide of adenyl cyclase-haemolysin (AC-Hly), which induces formation of protective antibodies against an infection by a bacteria selected from the group consisting of B. pertussis, B. parapertussis, and B. bronchiseptica when the nucleic acid or polypeptide is administered to a human or animal host. The nucleic acids are useful, for example, to induce a protective immune response in a host against infection by a bacteria selected from the group consisting of B. pertussis, B. parapertussis, and B. bronchiseptica.
US07902348B2
An isolated polynucleotide encodes JAK-3 protein. JAK-3 protein is a protein tyrosine kinase having a molecular weight of approximately 125 kDa which has tandem non-identical catalytic domains, lacks SH2 or SH3 domains, and is expressed in NK cells and stimulated or transformed T cells, but not in resting T cells. The protein itself and antibodies to this protein are also presented. Further, methods of identifying therapeutic agents for modulating the immune system make use of the foregoing.
US07902346B2
Disclosed is a fusion protein containing a FK506 binding protein and a cell-transducing domain. Also, disclosed is a method of making the fusion protein and use of the fusion protein in a pharmaceutical or cosmetic composition. The cell-transducing domain is, for example, a PEP-1.
US07902338B2
The present invention provides humanized, chimeric and human anti-CD19 antibodies, anti-CD19 antibody fusion proteins, and fragments thereof that bind to a human B cell marker. Such antibodies, fusion proteins and fragments thereof are useful for the treatment and diagnosis of various B-cell disorders, including B-cell malignancies and autoimmune diseases. In more particular embodiments, the humanized anti-CD19 antibodies may comprise one or more framework region amino acid substitutions designed to improve protein stability, antibody binding and/or expression levels. In a particularly preferred embodiment, the substitutions comprise a the substitution of serine for phenylalanine at Kabat residue 91 in the human framework region in the hA19 VH sequence.
US07902337B2
Soybean cyst nematode and soybean sudden death syndrome resistance genes, soybean cyst nematode and soybean sudden death syndrome resistant plant lines, and methods of breeding and engineering same.
US07902332B2
Methods for introducing fluorine atom onto a polypeptide are provided. Also provided are linkers, bioconjugates, and bifunctional compound agents made using the methods, linkers, and bioconjugates. The methods comprise: (i) providing a linker comprising a thiol-reactive terminus and an aldehyde-reactive terminus; (ii) reacting the thiol-reactive terminus of the linker with a polypeptide comprising at least one thiol group or a reactive derivative thereof; and (iii) subsequently reacting the aldehyde-reactive terminus of the linker with a fluorine-substituted aldehyde.
US07902329B2
Disclosed are peptides that inhibit the enzymatic activity of tyrosinase, as well as formulations and methods for their use in the reduction of skin pigmentation, and methods of administering the inhibitory peptides in a topical formulation. Peptide sequences disclosed include KFEKKFEK and YRSRKYSSWY.
US07902328B2
The invention relates to neuromodulatory oligomers of the amyloid-β(1-42) protein, a particular production method, by means of which the oligomer can be obtained in a reproducible manner at high yield, the use of the oligomers as diagnostic and therapeutics agents, for the generation of oligomer-specific antibodies and for the discovery of substances which can interact with the oligomers and in the formation thereof. Corresponding methods for the production of the antibodies and for discovery of the substances are also disclosed as are the antibodies themselves and the use of the antibodies or substances as diagnostic and therapeutic agents. The invention further relates to derivatives of the oligomers and oligomers based on abbreviated forms of the amyloid-β(1-42) proteins, the production and use thereof.
US07902323B1
Methods of forming materials containing precursors to electrically conductive polymers and electrically conductive polymers are described which have a high degree of crystallinity. The high degree of crystallinity is achieved by preparing the materials under conditions which provide a high degree of mobility to the polymer molecules permitting them to associate with one another to form a crystalline state. High levels of electrical conductivity are achieved in in the electrically conductive materials without stretch orienting the material. The enhanced electrical conductivity is isotropic as compared to a stretch oriented film which has isotropic electrical conductivity. In the preferred embodiment, additives are added to a solution containing a solvent and the precursor or electrically conductive polymer. The additives are preferably plasticizer of diluents. As the solvent is removed the material dries and contains a higher degree of crystallinity than in the absence of the additive.
US07902315B2
The present invention relates to a process for preparing radiation-curing binders containing allophanate groups by reacting at temperatures of ≦130° C. A) one or more compounds containing uretdione groups with B) one or more OH-functional compounds which contain groups which react, with polymerization, with ethylenically unsaturated compounds on exposure to actinic radiation (radiation-curing groups), C) optionally NCO-reactive compounds other than B), in the presence of D) a catalyst containing at least one zinc compound, to form allophanate groups by opening the uretdione ring.
US07902314B2
Disclosed herein is a composition comprising a structure (M1)a(ME)b(D1)c(D2)d(T)e(Q)f, wherein M1=R1R2R3SiO1/2; ME=R4R5RESiO1/2; D1=R6R7SiO2/2; D2=R8R9SiO2/2; T=R10SiO3/2; and Q=SiO4/2; wherein each RE is independently a monovalent hydrocarbon radical containing an epoxy group; R9 comprises a structure -L1-Si(R11)g(OR12)3-g or L2(D3)h(M2)i-L3-Si(R13)g′(OR14)3-g′, wherein L1, L2, and L3 are independently divalent linking groups; g and g′ independently have a value from 0 to 2; M2=R15R16R17SiO1/2; D3=R18R19SiO2/2; wherein R1, R2, R3, R4, R5, R6, R7, R8, R10, R11, R12, R13, R14, R15, R16, R17, R18, and R19 are independently monovalent hydrocarbon radicals; wherein a, b, c, d, e, f, h, and i are stoichiometric subscripts that are zero or positive subject to the following limitations: b has a value of 2; d is greater than or equal to 1; when (a+c+e+f) is equal to zero, (b+d) is greater than or equal to 3; and when i=0, h is at least 1.
US07902312B2
Several Michael addition adducts of vinylamines with α,β. -unsaturated alkyl carbonyl compounds including amides, esters and acids, particularly acrylamide are presented. Additionally, a process for producing these Michael addition adducts is described. These adducts are generally useful in the manufacture of paper and are particularly useful as dry strength additives to make paperboard products using a papermaking machine.
US07902298B2
High-temperature-curing reactive compositions based on natural and/or synthetic elastomers containing olefinic double bonds, and on vulcanizing agents, are described, which contain at least one liquid polyene having a molecular weight between 400 and 80,000 and at least one liquid polybutadiene having a narrow molecular weight distribution and a microstructure of 10 to 20% vinyl-1,2 double bonds, 50 to 60% trans-1,4 double bonds, and 25 to 35% cis-1,4 double bonds in the molecule. These compositions furthermore contain a vulcanizing system of sulfur and accelerators and/or, if applicable, quinone oximes. These compositions are suitable for use as a single-component adhesive, sealant, or coating compound in automobile manufacture, with high tensile shear strength and high impact peel strength even, in particular, at low temperatures.
US07902296B2
A composition includes specific amounts of a high molecular weight poly(arylene ether), a rubber-modified polystyrene, and a hydrogenated block copolymer. The use of the high molecular weight poly(arylene ether) unexpectedly provides substantially improved durability to articles molded from the composition. The composition is particularly useful for molding hot water pipes and fittings.
US07902294B2
The present invention provides novel filled silicone compositions comprising a nano-particulate metal oxide filler selected from nano-particulate monoclinic alpha-phase bismuth oxide, nano-particulate erbium oxide, and mixtures thereof. The new composite compositions exhibit a combination of outstanding performance characteristics in both the cured and uncured states. Thus, the uncured formulations are typically free flowing liquids which are self-leveling, which de-gas readily under vacuum, are readily colorable through the addition of pigments, and which cure at temperatures of about 60° C. The cured compositions possess outstanding acoustic characteristics which make them ideally suited for use in applications such as acoustic lenses for medical imaging and therapy. For example, the acoustic impedance of compositions provided by the present invention is closely matched to the acoustic impedance of human tissue. This may result in an enhancement of ultrasound transmission efficiency between the lens of an ultrasound probe comprising such a composition and the patient.
US07902292B2
The present invention relates to two-component paint, which comprises: a first liquid comprising at least one colloidal metal solution which includes at least colloidal metal particles with a sulfur compound of low molecular weight on the particle surfaces and a dispersion medium, the solution containing not less than 1 wt. % of the colloidal metal particles and has a pH of 8-14, and a second liquid comprising at least a curable resin component.
US07902289B2
The present invention provides a rubber composition for coating a belt layer steel cord, which inhibits separation from the steel cord when running the tire. Specifically, the present invention provides a rubber composition for coating a belt layer steel cord comprising (A) 2.5 to 4 parts by weight of sulfur, (B) 0.5 to 5 parts by weight of resorcin or modified resorcin condensate, (C) 0.3 to 3 parts by weight of partial condensate of hexamethylol melamine pentamethyl ether or partial condensate of hexa methoxy methylol melamine, and (D) organic acid cobalt, based on 100 parts by weight of a rubber component; wherein the cobalt content in the organic acid cobalt (D) is 0.05 to 0.8 part by weight based on 100 parts by weight of the rubber component, and a steel cord obtained by coating with the rubber composition.
US07902281B2
An object of the present invention is to provide a resin composition which is increased in heat resistance (high crystallinity) and transparency without impairing rigidity which a thermoplastic resin inherently has and a molded article containing the resin composition. A thermoplastic resin composition relating to the present invention includes a thermoplastic resin (A) and a crystal nucleating agent (B) composed of tris(amino acid ester)amides of trimesic acid. The crystal nucleating agent (B) is preferably tris(valine ester)amides of trimesic acid or tris(leucine ester)amides of trimesic acid, and the thermoplastic resin (A) is preferably a lactic acid resin and more preferably a polylactic acid.
US07902278B2
A functionalized elastomer defined by the formula where π includes a polymer chain, θ includes a group 14 element, R1 and R2 each independently include hydrogen, or a monovalent organic group, or a polymer chain, R3 and R4 each independently include a divalent organic group or a covalent bond, R5, R6, R7, R8 and R9 each independently include a monovalent organic group or a hydrogen atom.
US07902275B2
Composite materials are disclosed having low filler percolation thresholds for filler materials into the composite matrix material along with methods of controlling filler interconnectivity within the composite matrix material. Methods are, thus, disclosed that provide the ability to control the desired properties of the composites. The composites of the present disclosure are characterized by a “pseudo-crystalline” microstructure formed of matrix particles and filler particles where the matrix particles are faceted and substantially retain their individual particle boundaries and where the filler particles are interspersed between the matrix particles at the individual matrix particle boundaries such that the filler particles form a substantially interconnected network that substantially surrounds the individual faceted matrix particles. In an exemplary embodiment, the composites are formed by selecting matrix particles and filler particles wherein the ratio of the average size of the matrix particles to the average size of the filler particles is about 10 or more. The selected matrix particles exhibit a glass transition temperature. The matrix particles and the filler particles are mechanically mixed and then subjected to a temperature above the glass transition temperature of the matrix particles and a compression pressure for a period of time sufficient to cause the matrix particles to undergo deformation so as to compress them together eliminating void spaces between the particles without melting the matrix material. The method is also demonstrated to work in combination with more standard art methods such as solution mixing for the purposes of achieving additional control of the properties.
US07902271B2
Compositions of vinyl halide polymers such as PVC are rendered compostable by a prodegradant system of a monomeric adduct of an organotitanate or zirconate and an organotin. PVC sheets and composites are compostable in landfills.
US07902267B2
The present invention provides a thermosetting and photocurable coating composition obtained by incorporating a copolymer of a maleimide group-containing monomer with other monomer(s) or a specific maleimide compound into a composition comprising a hydroxyl-containing resin and a curing agent and optionally containing an unsaturated compound; and a method of forming a coating film using the coating composition.
US07902263B2
The invention relates to a process for making modified polybutylene terephthalate random copolymers from a polyethylene terephthalate component. In one embodiment, the invention relates to a two step process in which a 1,4-butane diol component reacts with a polyethylene terephthalate component under conditions that depolymerize the polyethylene terephthalate component into a molten mixture and the molten mixture is placed under subatmospheric conditions that produce the modified polybutylene terephthalate random copolymers. In another embodiment, the invention relates to a three step process in which a diol component selected from the group consisting of ethylene glycol, propylene glycol, and combinations thereof reacts with a polyethylene terephthalate component under conditions sufficient to depolymerize the polyethylene terephthalate component into a first molten mixture; and where the first molten mixture is combined with 1,4-butane diol under conditions that create a second molten mixture that is subsequently placed under subatmospheric conditions that produce the modified polybutylene terephthalate random copolymers. The invention also relates to compositions made from processes of the invention.
US07902238B2
The invention relates to compounds of formula wherein R1, R2, and R3 are as defined herein and to a pharmaceutically suitable acid addition salts thereof for the treatment of CNS disorders.
US07902224B2
The present invention is directed to compounds of formula (I): wherein R represents a methyl or an ethyl group X represents N, C—H or C—CH3 when X represents C—H or C—CH3, Y represents N when X represents N, Y represents C—H and physiologically functional derivatives thereof, pharmaceutical compositions comprising the compounds, the use of the compounds for the manufacture of medicaments particularly for the treatment of inflammatory and/or allergic conditions, processes for the preparation of the compounds, and chemical intermediates in the processes for the manufacture of the compounds.
US07902220B2
The invention provides 8-azabicyclo[3.2.1]octyl-2-hydroxybenzamide compounds of formula (I): wherein R2, R7, and m are defined in the specification, or a pharmaceutically -acceptable salt thereof, that are antagonists at the mu opioid receptor. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat conditions associated with mu opioid receptor activity, and processes and intermediates useful for preparing such compounds.
US07902207B2
A process for producing an amine which is characterized by reacting an imine with a nucleophilic compound (except a trialkylsilyl vinyl ether) in the presence of a phosphoric acid derivative represented by the formula (1): wherein A1 represents a spacer; X1 and X2 represent each independently a divalent nonmetal atom or a divalent nonmetal atomic group; and Y1 is oxygen or sulfur. The invention provides a process by which amines (particularly optically active amines) useful as intermediates of medicines, agricultural chemicals, or the like can be produced without special post-treatment in high yield at high optical purity; and phosphoric acid derivatives (particularly optically active phosphoric acid derivatives) useful in the production of the amines.
US07902206B2
Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin α and rifaximin β, and a poorly crystalline form named rifaximin γ, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means of a crystallization carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a determinate temperature and for a determinate period of time, followed by a drying carried out under controlled conditions until reaching a settled water content in the end product, are the object of the invention.
US07902203B2
The present invention provides an HCV polymerase inhibiting compound having the formula (I) and a composition comprising a therapeutically effective amount of said compound. The present invention also provides a method for inhibiting hepatitis C virus (HCV) polymerase, a method for inhibiting HCV viral replication, and a method for treating or preventing HCV infection. Processes for making said compounds, and synthetic intermediates employed in said processes, are also provided.
US07902199B2
The present application discloses a compound, or enantiomers, stereoisomers, rotamers, tautomers, racemates or prodrug of said compound, or pharmaceutically acceptable salts, solvates or esters of said compound, or of said prodrug, said compound having the general structure shown in Formula 1: or a pharmaceutically acceptable salt, solvate or ester thereof. Also disclosed is a method of treating chemokine mediated diseases, such as, palliative therapy, curative therapy, prophylactic therapy of certain diseases and conditions such as inflammatory diseases (non-limiting example(s) include, psoriasis), autoimmune diseases (non-limiting example(s) include, rheumatoid arthritis, multiple sclerosis), graft rejection (non-limiting example(s) include, allograft rejection, zenograft rejection), infectious diseases (e.g., tuberculoid leprosy), fixed drug eruptions, cutaneous delayed-type hypersensitivity responses, ophthalmic inflammation, type I diabetes, viral meningitis and tumors using a compound of Formula 1.
US07902198B2
Alcoholates of aripiprazole are useful as pharmaceuticals and/or as intermediates in making aripiprazole Form A or Form B.
US07902188B2
The present invention provides for compounds of formula (I), (Ia) and (Ib) Wherein: A is selected from C—X and N, B is selected from C—Y and N, R1 is selected from H and (C1-C6)alkyl, R2 is selected from H and (C1-C6)alkyl, X is selected from H, HO, C(O)NH2, NH2 Y is selected from H, HO, NH2, Br, Cl and F Z is selected from H, HO, F, CONH2 and CN; And pharmaceutically acceptable salts, solvates and prodrugs thereof; With the provisos that: for a compound of formula (I), (Ia) or (Ib), when A is C—X, B is C—Y, R1 is H or (C1-C6)alkyl and R2 is H or (C1-C6)alkyl at least one of X, Y and Z must be OH; for a compound of formula (I), when A is C—X and B is C—Y, Y is H, Z is H, R1 is H and R2 is H, then X cannot be OH; these compounds are useful as a medicament.
US07902181B2
The present invention provides compounds of formula (I) in which n, y, X1, X2, A, B, R1, R2, R3, R4 and R5 are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them and their use in therapy.
US07902174B2
Chemical compounds, being the alkyl sulfate of sulfated saccharides, particularly, dextrin, dextran, and cyclodextrin, and pharmaceutical compositions containing these compounds. The compounds of the invention provide antiviral activity, particularly in the treatment and prevention of sexually-transmitted diseases. Methods of treating viral infection and preventing viral transmission include administration include administration of the compounds of the invention orally, topically, subcutaneously, by muscular injection, by intraperitoneal injection and by intravenous injection.
US07902169B2
The present invention relates to methods and compositions that decrease intraocular pressure (IOP) of the eye. The compositions of the invention comprise short interfering nucleic acid molecules (siNA) including, but not limited to, siRNA that decrease expression of genes associated with production or drainage of intraocular fluid. The compositions of the invention can be used in the preparation of a medicament for the treatment of an eye conditions displaying increased IOP such as glaucoma, infection, inflammation, uveitis, and diabetic retinopathy. The methods of the invention comprise the administration to a patient in need thereof an effective amount of one or more siNAs of the invention.
US07902157B2
Disclosed are compounds of the formula wherein Z1 is —CH2—or —C(O)—, R4 and R5 are carbon chains (and optionally, together can form a C2 bridge), u and v are independently an integer of 0-3 such that there sum is from 3 to 5, and R2 is heteroaryl, and R1 and R3 are as defined herein. Also disclosed are methods of treating pain, and methods of inhibiting the absorption of cholesterol using a compound of formula I.
US07902150B2
There is provided the use of monomeric TGF-βs, or there fragments or derivatives, as medicaments. These medicaments preferably comprise monomeric TGF-β3, or fragments or derivatives thereof. The medicaments provided may be used in the acceleration of wounding and/or the inhibition of scarring, in the promotion of epithelial regeneration, or in the prevention and/or treatment of fibrotic disorders.
US07902146B2
A therapeutic or prophylactic agent for cancer is disclosed which damages the membrane and kills cancer cells, in particular of the blood-forming system, having membrane protein aggregates which contain several core histones or largely core-like histones and/or their parts. The therapeutic or prophylactic agent contains at least one pure histone or its active sequence section selected from the group composed of histone H1, H1 subtypes, H2A, H2B, H2A:H2B dimer, H3 and H4, covalent modified histones of the above-mentioned type and/or their active sections and functionally and structurally similar proteins (protamines, histone-like proteins of prokaryotic and archae bacteria).
US07902145B2
Methods of sterilizing dermal fillers and injectable collagen material have been developed which reduce the level of active biological contaminants or pathogens without adversely affecting the material, i.e., wherein the dermal fillers and injectable collagen material retain their same properties before and after its terminal sterilization. In one embodiment the method for sterilizing the dermal filler or injectable collagen material that is sensitive to radiation contains the steps of protecting the filler or material from radiation, and irradiating the filler or material with a suitable dose of radiation for a time and at a rate effective to sterilize the filler or injectable material. In a preferred embodiment the method for sterilizing the dermal filler or injectable collagen material that is sensitive to radiation includes the steps of a) freezing the filler or material at a temperature below its freezing temperature, which is generally below 0° C. and b) irradiating the filler or material with a suitable dose of radiation at an effective rate for a time effective to sterilize the filler or material. The exposure of the radiation differs depending upon the density of the filler or material, but is preferably between 5 kGy and 12 kGy and more preferably between 6 kGy and 8 kGy. These doses result in a sterility assurance level (SAL) of 10−6 SAL for the filler or material.
US07902144B2
The invention relates to transport molecule binding ligand compounds which comprise a therapeutically and/or diagnostically active substance and a carrier molecule-affine substance with a high association constant to the carrier molecule. The invention also relates to medicaments containing these ligand compounds and to diagnostic kits.
US07902134B1
A moisturizing, personal cleansing composition with a limited number of naturally-derived, naturally processed, generally regarded as safe (GRAS), biodegradable ingredients comprising a plurality of oleosomes, an anionic surfactant, a non-ionic surfactant, a lipoaminoacidic surfactant, and a humectant. The personal cleansing composition optionally contains a fragrance, vitamin, essential oil, thickener, exfoliant, preservative, plant extract and other beneficial naturally-derived, naturally processed, generally regarded as safe (GRAS), biodegradable ingredients such as royal jelly. The moisturizing, personal cleansing composition cleanses and moisturizes as well as or better than commercial compositions containing synthetically derived cleansing and moisturizing agents.
US07902125B2
Thermoset polymer particles are used in many applications requiring lightweight particles possessing high stiffness, strength, temperature resistance, and/or resistance to aggressive environments. The present invention relates to the use of two different methods, either each by itself or in combination, to enhance the stiffness, strength, maximum possible use temperature, and environmental resistance of such particles. One method is the application of post-polymerization process steps (and especially heat treatment) to advance the curing reaction and to thus obtain a more densely crosslinked polymer network. In general, its main benefits are the enhancement of the maximum possible use temperature and the environmental resistance. The other method is the incorporation of nanofillers, resulting in a heterogeneous “nanocomposite” morphology. In general, its main benefits are increased stiffness and strength. Nanofiller incorporation and post-polymerization heat treatment can also be combined to obtain the benefits of both methods simultaneously. The present invention relates to the development of thermoset nanocomposite particles. It also relates to the optional further improvement of the heat resistance and environmental resistance of said particles via post-polymerization heat treatment. Furthermore, it also relates to processes for the manufacture of said particles. Finally, it also relates to the use of said particles in the construction, drilling, completion and/or fracture stimulation of oil and natural gas wells; for example, as a proppant partial monolayer, a proppant pack, an integral component of a gravel pack completion, a ball bearing, a solid lubricant, a drilling mud constituent, and/or a cement additive.
US07902121B2
T cells are profiled with respect to their expression of antigen receptor. The cells are arrayed on a planar or three-dimensional substrate through binding to immobilized or partially diffused MHC-antigen complexes. The cells may further be characterized with respect to their ability to respond to external stimulus in the microenvironment. External stimuli include cell-cell interactions, response to factors, and the like.
US07902120B2
Superconductor wires or layers having improved properties and methods for making the same are described. The superconducting layer includes a rare earth element-alkaline earth element-transition metal oxide having an average stacking fault density that is greater than about 0.01 nm−1, wherein two or more rare earth cations form the rare earth element. To form the superconductor layer of the present invention, a layer having a rare earth element-alkaline earth element-transition metal oxide substantially in a first crystal structure can be provided to a substrate where two or more rare earth cations form the rare earth element. The layer can then be heated at a temperature that is greater than 550° C. under oxidizing conditions to form a high-temperature superconducting layer substantially in a second crystal structure.
US07902115B2
Herein are disclosed adducts of amines and polycarboxylic acids, and methods of making such adducts. Such adducts can be used to remove cyanogen chloride. Also disclosed are methods of providing such adducts on supports to form filter media. Also disclosed are methods of combining such filter media with catalysts and/or with porous polymeric webs to form filter systems.
US07902114B2
Using zeolites as the active adsorbent, adsorbent laminates have been fabricated with various sheet supports. These adsorbent laminates have been successfully operated for oxygen enrichment at high PSA cycle frequencies, such as upwards of at least 150 cycles per minute. Methods for making suitable adsorbent laminates are described. The methods generally involve forming a slurry comprising a liquid suspending agent, an adsorbent and a binder. Laminates are made by applying the slurry to support material or admixing support material with the slurry. The slurry can be applied to support material using a variety of techniques, including roll coaters, split roll coaters, electrophoretic deposition, etc. One method for making laminates by mixing support material with the adsorbent slurry comprises depositing the slurry onto a foraminous wire, draining the slurry material, and pressing the material to form a ceramic adsorbent paper. Spacers can be formed on adsorbent laminates to space one laminate from another. The spacer dimensions can be uniform, or can vary along a laminate, such as increasing in height from a first end to a second end of the laminate. Gas flow-through apertures also can be formed on laminates. The laminates are adjacent one another to define flow channel between adjacent bodies, whereby a portion of a gas flowing through the flow channels flows through the apertures to facilitate pressure equalization in the adsorbent structure.
US07902110B2
Provide that a useful catalyst for homogeneous hydrogenation, particularly a catalyst for homogeneous asymmetric hydrogenation for hydrogenation, particularly asymmetric hydrogenation, which is obtainable with comparative ease and is excellent in economically and workability, and a process for producing a hydrogenated compound of an unsaturated compound, particularly an optically active compound using said catalyst with a high yield and optical purity.
US07902107B2
Provided is an emission treatment system and method for simultaneously remediating the nitrogen oxides (NOx), particulate matter, and gaseous hydrocarbons present in diesel engine exhaust streams. The emission treatment system has an oxidation catalyst upstream of a soot filter coated with a material effective in the Selective Catalytic Reduction (SCR) of NOx by a reductant, e.g., ammonia. Also provided is a method for disposing an SCR catalyst composition on a wall flow monolith that provides adequate catalyst loading, but does not result in unsuitable back pressures in the exhaust.
US07902091B2
An improved process of substrate cleaving and a device to perform the cleaving are disclosed. In the traditional cleaving process, a layer of microbubbles is created within a substrate through the implantation of ions of a gaseous species, such as hydrogen or helium. The size and spatial distribution of these microbubbles is enhanced through the use of ultrasound energy. The ultrasound energy causes smaller microbubbles to join together and also reduces the straggle. An ultrasonic transducer is acoustically linked with the substrate to facilitate these effects. In some embodiments, the ultrasonic transducer is in communication with the platen, such that ultrasound energy can be applied during ion implantation and/or immediately thereafter. In other embodiments, the ultrasonic energy is applied to the substrate during a subsequent process, such as an anneal.
US07902089B2
An object of the present invention is to provide a new n-type transistor, different from the prior art, using a channel having a nanotube-shaped structure, and having n-type semiconductive properties. To realize this, a film of a nitrogenous compound 6 is formed directly on a channel 5 of a transistor 1 comprising a source electrode 2, a drain electrode 3, a gate electrode 4 and the n-type channel 5 having a nanotube-shaped structure and provided between the source electrode 2 and the drain electrode 3.
US07902088B2
A method is provided for fabricating a high quantum efficiency silicon (Si) nanoparticle embedded SiOXNY film for luminescence (electroluminescence—EL and photoluminescence—PL) applications. The method provides a bottom electrode, and deposits a Si nanoparticle embedded non-stoichiometric SiOXNY film, where (X+Y<2 and Y>0), overlying the bottom electrode. The Si nanoparticle embedded SiOXNY film is annealed. The annealed Si nanoparticle embedded SiOXNY film has an extinction coefficient (k) of less than about 0.001 as measured at 632 nanometers (nm), and a PL quantum efficiency (PLQE) of greater than 20%.
US07902079B2
A method for fabricating a recess pattern in a semiconductor device includes defining an active region on a substrate, forming a first mask pattern over the active region in a line type structure, forming a second mask pattern comprising an open region over the active region, the open region exposing a portion where the active region and the first mask pattern intersect, and etching the active region of the substrate exposed by the first and second mask patterns to form recess patterns.
US07902077B2
A semiconductor device manufacturing method includes: forming an etching mask having a predetermined circuit pattern on a surface of an etching target film disposed on a semiconductor substrate; etching the etching target film through the etching mask to form a groove or hole in the etching target film; removing the etching mask by a process including at least a process using an ozone-containing gas; and recovering damage of the etching target film caused before or in said removing the etching mask, while supplying a predetermined recovery gas.
US07902072B2
A metal-polishing composition includes colloidal silica particles, which has a ratio of minor axis/major axis of 0.2 to 0.8 and a surface at least partially covered with aluminum atoms, comprises in an amount of 50% or more with respect to total abrasives.The metal-polishing composition preferably includes an oxidizing agent, an organic acid or the like. The colloidal silica constituting the colloidal silica particles is preferably formed by hydrolysis of alkoxysilane. The major axis of the colloidal silica particles is preferably in a range of 20 nm to 100 nm.
US07902068B2
In one aspect of the present invention, a method of fabricating a semiconductor device may include forming a sacrificial film on a substrate, forming an insulating film on the sacrificial film, forming a plurality of first openings in the sacrificial film and the insulating film in a first region and a second region, depositing a conductive material in the plurality of the first openings, forming a second opening in the insulating film in the second region so as to expose the sacrificial film, and removing the sacrificial film in the first region via the second opening in the second region.
US07902057B2
Fin-FET devices and methods of fabrication are disclosed. The Fin-FET devices include dual fins that may be used to provide a trench region between a source region and a drain region. In some embodiments, the dual fins may be formed by forming a trench with fin structures on opposite sides in a protruding region of a substrate. The dual fins may be useful in forming single-gate, double-gate or triple-gate fin-FET devices. Electronic systems including such fin-FET devices are also disclosed.
US07902056B2
Devices and methods for plasma treated metal silicide layer formation are disclosed. In one embodiment, a method for manufacturing a semiconductor device comprises forming a metal layer on a silicon substrate, exposing the metal layer to a plasma, and thermally treating the silicon substrate and the metal layer to form a metal silicide layer.
US07902053B2
Formation and etching of an n type epitaxial layer and formation and etching of a p type epitaxial layer are alternately performed on the semiconductor substrate for at least three times to form all semiconductor layers, of the epitaxial layers. Thereby, impurity concentration profiles of the semiconductor layers can be uniform, and pn junctions can be formed vertically to a wafer surface. Furthermore, the semiconductor layers can each be formed with a narrow width, so that impurity concentrations thereof are increased. With this configuration, high breakdown voltage and low resistance can be achieved.
US07902052B2
A process and system are provided for processing at least one section of each of a plurality of semiconductor film samples. In these process and system, the irradiation beam source is controlled to emit successive irradiation beam pulses at a predetermined repetition rate. Using such emitted beam pulses, at least one section of one of the semiconductor film samples is irradiated using a first sequential lateral solidification (“SLS”) technique and/or a first uniform small grained material (“UGS”) techniques to process the such section(s) of the first sample. Upon the completion of the processing of this section of the first sample, the beam pulses are redirected to impinge at least one section of a second sample of the semiconductor film samples. Then, using the redirected beam pulses, such section(s) of the second sample are irradiated using a second SLS technique and/or a second UGS technique to process the at least one section of the second sample. The first and second techniques can be different from one another or substantially the same.
US07902049B2
A process for the plasma deposition of a layer of a microcrystalline semiconductor material is carried out by energizing a process gas which includes a precursor of the semiconductor material and a diluent with electromagnetic energy so as to create a plasma therefrom. The plasma deposits a layer of the microcrystalline semiconductor material onto the substrate. The concentration of the diluent in the process gas is varied as a function of the thickness of the layer of microcrystalline semiconductor material which has been deposited. Also disclosed is the use of the process for the preparation of an N-I-P type photovoltaic device.
US07902048B2
A method of forming a phase change layer may include providing a bivalent first precursor having germanium (Ge), a second precursor having antimony (Sb), and a third precursor having tellurium (Te) onto a surface on which the phase change layer is to be formed. The phase change layer may be formed by CVD (e.g., MOCVD, cyclic-CVD) or ALD. The composition of the phase change layer may be varied by modifying the deposition pressure, deposition temperature, and/or supply rate of reaction gas. The deposition pressure may range from about 0.001-10 torr, the deposition temperature may range from about 150-350° C., and the supply rate of the reaction gas may range from about 0-1 slm. Additionally, the above phase change layer may be provided in a via hole and bounded by top and bottom electrodes to form a storage node.
US07902047B2
A dual-chamber reactor can include a housing enclosing a volume having a divider therein, where the divider defines a first chamber and a second chamber. The divider can include a substrate holder that supports at least one substrate and exposes a first side of the substrate to the first chamber and a second side of the substrate to the second chamber. The first chamber can include an inlet for delivering at least one reagent to the first chamber for forming a film on the first side of the substrate, and the second chamber can include a removal device for removing material from the second side of the substrate.
US07902046B2
Growth of SiGe on a significantly lattice mismatched substrate (e.g., Si) is provided by depositing a SiGe buffer layer at a growth temperature, then annealing the resulting structure at a temperature higher than the growth temperature. Additional buffer layers can be included following the same steps. The SiGe buffer is significantly lattice mismatched with respect to the substrate, and is preferably substantially lattice matched with a SiGe device to be grown on top of the buffer. The resulting buffer structure is relatively thin and provides low defect density, and low surface roughness. Disadvantages of thick graded buffer layers, such as high cost, high surface roughness, mechanical fragility, and CTE mismatch, are thereby avoided.
US07902037B2
A method for fabricating an isolation structure in a memory device includes forming a first trench in a cell region of a semiconductor substrate and a second trench in a peripheral region of the semiconductor substrate. The method also includes oxidating the surface of the first and second trenches to form a sidewall oxide layer; depositing a tetraethylorthosilicate(TEOS) layer on the sidewall oxide layer; forming a silicon nitride layer and a silicon oxide layer on the TEOS layer; selectively removing portions of the silicon nitride and silicon oxide layers on the second trench to expose a portion of the underlying TEOS layer; coating a flowable insulation layer that fills the first and second trenches; and curing the flowable insulation layer.
US07902031B2
A method for creating NAND flash memory. Source implantations are performed at a first implantation angle to areas between stacked gate structures of a NAND string. Drain implantations are performed at a second implantation angle to areas between the stacked gate structures. The implantations can dope a source line area while not doping a bit line contact area, and providing an additional implantation for the bit line contact area, or dope the bit line contact area while not doping the source line area, followed by an additional implantation for the source line area, or dope neither the source line area nor the bit line contact area, followed by additional implantations for the source line area and the bit line contact area.
US07902028B2
The invention includes methods of forming field effect transistors, methods of forming field effect transistor gates, methods of forming integrated circuitry comprising a transistor gate array and circuitry peripheral to the gate array, and methods of forming integrated circuitry comprising a transistor gate array including first gates and second grounded isolation gates. In one implementation, a method of forming a field effect transistor includes forming masking material over semiconductive material of a substrate. A trench is formed through the masking material and into the semiconductive material. Gate dielectric material is formed within the trench in the semiconductive material. Gate material is deposited within the trench in the masking material and within the trench in the semiconductive material over the gate dielectric material. Source/drain regions are formed. Other aspects and implementations are contemplated.
US07902026B2
A method of fabricating a semiconductor device having a vertical channel transistor, the method including forming a hard mask pattern on a substrate, forming a preliminary active pillar by etching the substrate using the hard mask pattern as an etch mask, reducing a width of the preliminary active pillar to form an active pillar having a width less than that of the hard mask pattern, forming a lower source/drain region by implanting impurity ions into the substrate adjacent to the active pillar using the hard mask pattern as an ion implantation mask, and forming an upper source/drain region on the active pillar and vertically separated from the lower source/drain region.
US07902017B2
A process of forming an electronic device can include providing a workpiece comprising a substrate, including an underlying doped region, and a semiconductor layer overlying the underlying doped region, wherein the semiconductor layer has a primary surface spaced apart from the underlying doped region. The process can also include forming a vertically-oriented conductive region extending from the primary surface to the underlying doped region, and forming a horizontally-oriented doped region adjacent to the primary surface. In a finished form of the electronic device, the horizontally-oriented doped region extends further in a lateral direction toward a region where a source region has been or will be formed, as compared to the vertically-oriented conductive region. The electronic device includes a transistor that includes the underlying doped region, the vertically-oriented conductive region, and the horizontally-oriented doped region.
US07902001B2
Provided is a sacrifice layer formed on a first substrate. A thin film laminated body is formed on the sacrifice layer. A separation groove exposing the sacrifice layer is formed to divide the thin film laminated body into at least one thin film device. The sacrifice layer is partially removed using a dry etching process. After the partial removal of the sacrifice layer, a remaining sacrifice layer region maintains the thin film device on the first substrate. A supporting structure is temporarily joined to the thin film device. The thin film device joined to the supporting structure is separated from the first substrate. Then, the remaining sacrifice layer is removed. The thin film device joined to the supporting structure is joined to a second substrate. Finally, the supporting structure is separated from the thin film device.
US07901991B2
The present invention relates to a method for manufacturing thin-film photovoltaic panels by the use of a sealing means composed by a polymeric tie layer comprising getter system composed of a polymer with low H2O transmission having dispersed in its inside H2O sorption material, and two outer polymeric layers with the composite getter system therebetween, as well as to polymeric tri-layer for the manufacturing of photovoltaic panels.
US07901990B2
In one embodiment, a method for forming a molded flat pack style package includes attaching electronic chips to an array lead frame, which includes a plurality of elongated flag portions with tab portions and a plurality of leads. The method further includes connecting the electronic chips to specific leads, and then molding the array lead frame while leaving portions of the leads exposed to form a molded array structure. The molded array structure is then separated to provide molded flat pack style packages having exposed leads for insertion mount and exposed tab portions. In an alternative embodiment, the separation step produces a no-lead configuration with exposed tab portions.
US07901978B2
The core metal of a protein such as ferritin is used as a nucleus for crystallizing a silicone thin film and then the thus crystallized film is employed in the channel part of a thin-film transistor. By aligning the protein on the surface of amorphous silicone and heating, the crystallinity is controlled. In the case of ferritin, the core diameter of the protein is 7 mm. That is, this protein is highly even in size (i.e., the metal content). Thus, the amount of the protein to be deposited on the amorphous silicone surface can be accurately controlled by controlling the protein core density. Furthermore, the type of the core metal can be altered by chemical reactions and the above method is applicable not only to amorphous silicone but also to amorphous films of various types such as germanium. Thus, the amount of nickel required in crystallization is controlled by using a protein. Moreover, the distribution density of the nickel core is controlled to thereby conduct crystallization at a desired crystal size.
US07901971B2
A method for packaging a sensor device having a sensitive structure integrated on a semiconductor chip is provided. When molding the device package, an inward extending section of the mold maintains an access opening to the sensor. A buffer layer is arranged on the chip between the inward extending section and the sensitive structure. The buffer layer protects the sensitive structure from damage by the inward extending section and acts as a seal while casting the housing. The buffer layer also covers at least part of the semiconductor electronic components of the circuitry integrated onto the chip. By covering these components, mechanical stress, as it is e.g. caused by different thermal expansion coefficients of the packaging and the chip, can be reduced.
US07901969B2
A micro-mirror manufacturing method for dividing a plurality of micro-mirror devices each having at least one mirror, formed on a semiconductor wafer into individual micro-mirror devices can be provided. The manufacturing method comprises a step of depositing an inorganic protection layer on the mirror before separating the micro-mirror devices from the wafer and a step of removing the inorganic protection layer after separating the micro-mirror devices from the wafer.
US07901968B2
Some embodiments of the invention are related to manufacturing semiconductors. Methods and apparatuses are disclosed that provide thin and fully relaxed SiGe layers. In some embodiments, the presence of oxygen between a single crystal structure and a SiGe heteroepitaxial layer, and/or within the SiGe heteroepitaxial layer, allow the SiGe layer to be thin and fully relaxed. In some embodiments, a strained layer of Si can be deposited over the fully relaxed SiGe layer.
US07901967B2
A method for dicing a semiconductor substrate includes: forming a reforming layer in the substrate by irradiating a laser beam on the substrate; forming a groove on the substrate along with a cutting line; and applying a force to the substrate in order to cutting the substrate at the reforming layer as a starting point of cutting. The groove has a predetermined depth so that the groove is disposed near the reforming layer, and the force provides a stress at the groove.
US07901961B2
An organic light emitting display device capable of hermetically sealing a space between a deposition substrate and an encapsulation substrate with inorganic sealing materials is disclosed. One embodiment of the organic light emitting display device includes a first substrate including power supply lines formed on an array, and a circumference of the array, of an organic light emitting diode, and connected to a pad unit through the power pad line to supply a power source to each of the organic light emitting diodes; a second substrate arranged on at least the array of the first substrate; and an inorganic sealing material for sealing an inner space between the first substrate and the second substrate while forming a closed boundary, wherein the inorganic sealing material is not overlapped with a region in which the power supply line is formed.
US07901957B2
A method of forming a semiconductor package is disclosed including disguising the test pads. Test pads are defined in the conductive pattern of the semiconductor package for allowing electrical test of the completed package. The test pads are formed in shapes such as letters or objects so that they are less recognizable as test pads.
US07901956B2
A semiconductor package includes a substrate having a bond pad disposed on a top surface of the substrate. A first passivation layer is formed over the substrate and bond pad. The first passivation layer has an opening to expose the bond pad. An under bump metallurgy is formed over the first passivation layer. An end of the under bump metallurgy extends beyond an end of the bond pad. A second passivation layer is formed over the under bump metallurgy. The second passivation layer has a first opening to expose a first surface of the under bump metallurgy, and a second opening which is etched to expose a second surface of the under bump metallurgy. A solder ball is attached to the first surface of the under bump metallurgy to provide electrical connectivity. The second opening in the second passivation layer receives a probe needle to test the semiconductor device.
US07901948B2
The invention relates to the use of molecular tweezers as sensitive materials in chemical sensors intended to detect or assay organic compounds in the vapour state, and in particular nitro compounds.These molecular tweezers correspond to the general formula (I): in which: MC1 and MC2 represent macrocycles; p and q are equal to 0 or 1; X and Y are optionally substituted C1 to C10 alkylene groups; while E represents an optionally substituted cyclic or heterocyclic spacer group; and in which MC1 and MC2 are positioned facing each other. Fields of application: detection of explosives, control and monitoring of atmospheric pollution and of the quality of ambient air in relatively confined spaces, and monitoring of industrial sites.
US07901944B2
Methods for determining the amount of vitamin D compounds in a sample are provided. The methods can employ LC-MS/MS techniques and optionally the use of deuterated internal standards. Methods for diagnosing vitamin D deficiencies are also provided.
US07901935B2
This invention encompasses the identification and isolation of genes that confer disease control properties in plants, as well as plants comprising such genes. These genes are derived from the following sources: Nicotiana benthamiana, Oryzae sativa (var. Indica IR7), Papaver rhoeas, Saccharomyces cerevisiae and Trichoderma harzianum (Rifai 1295-22). The control conferred is against the one or more of the following phytopathogens: Aspergillus flavus, Cercospora zeae-maydis, Fusarium monilforme, Fusarium graminearum, Helminthosporium maydis, Phoma lingam, Phomopsis helianthi, Phytopthera infestans, Pyricularia oryzae, Pythium ultimum, Rhizoctonia solani, Sclerotinia sclerotiorum, Ustilago maydis, and Verticillium dahliae. Further, this invention encompasses other homologous and heterologous sequences with a high degree of functional similarity.
US07901926B2
Disclosed herein are two Lactobacillus isolates having anti-inflammatory activities and beneficial probiotic properties, i.e., Lactobacillus sakei GMNL-76 and Lactobacillus reuteri GMNL-89, which were deposited in the Biosource Collection and Research Center (BCRC) of the Food Industry Research and Development Institute (FIRDI) under accession numbers BCRC 910355 and BCRC 910340 and in the China Center for Type Culture Collection (CCTCC) under accession numbers CCTCC M 207153 and CCTCC M 207154, respectively. The two Lactobacillus isolates and their sub-cultured offspring can be used in the preparation of a variety of food products, and in the manufacture of pharmaceutical compositions for treating and/or alleviating diseases associated with inflammation, such as rheumatoid arthritis.
US07901921B2
The present invention is directed to an improved method of purifying virus, particularly reovirus. Infectious virus can be extracted from a cell culture with a detergent to produce high titers of virus, and the virus can then be purified by simple steps such as filtration and column chromatography. Viruses and compositions comprising the viruses prepared according to the present invention are also provided.
US07901917B2
Compositions comprising truncated tryptophanyl-tRNA synthetase polypeptides useful for regulating angiogenesis, as well as nucleic acids encoding such tRNA synthetase polypeptides are described. Methods of making and using such compositions are also disclosed.
US07901916B2
The present invention relates to a method for producing hydrogen by batch process capable of replacing the existing complex continuous organic waste treatment system by using pretreated organic waste not only as a substrate but also an inoculum. According to the present invention, the existing complex continuous process can be changed into a simple batch process, thereby reducing the installment costs and operational costs. It is possible to obtain economic operation because a long initial start-up period is not required.
US07901908B2
Described is the production of proteins in a host cell. More specifically, described are methods for improving expression of two or more proteins in a cell or host cell. The methods are suited for production of, for example, recombinant antibodies that can be used in pharmaceutical preparations or as diagnostic tools. In one embodiment, provided is a method for obtaining a cell that expresses two or more proteins comprising providing the cell with two or more protein expression units encoding two or more proteins, characterized in that at least two of the protein expression units comprise at least one STAR sequence.
US07901905B2
The present invention discloses a method for modulating the production of a protein from a polynucleotide in a CHO cell by replacing at least one codon of the polynucleotide with a synonymous codon that has a higher or lower translation efficiency in the CHO cell than the codon it replaces, or by introducing into the CHO cell a polynucleotide that codes for an iso-tRNA which limits the rate of production of the polypeptide and which corresponds to a codon of the first polynucleotide. The present invention also discloses the use of a protein-encoding polynucleotide whose codon composition has been modified for enhanced production of the protein in CHO cells.
US07901899B1
The invention provides a method using a hemocyte preparation, for example, Limulus amebocyte lysate, for detecting in a single assay the presence of at least one of a Gram negative bacterium, a Gram positive bacterium, and a fungus in a sample of interest. The method exploits the differential reactivity of Gram negative bacteria, Gram positive bacteria, and fungi with the hemocyte preparation to produce measurable changes in a property, for example, an optical property, of the mixture. Because the Gram negative bacteria, Gram positive bacteria and fungi each produce different changes in a given property, for example, an optical property, it is possible to classify the type of microorganism present in the sample of interest.
US07901890B2
Aspects described and claimed herein provide methods to insert multiple DNA adaptors into a population of circular target DNAs at defined positions and orientations with respect to one another. The resulting multi-adaptor constructs are then used in massively-parallel nucleic acid sequencing techniques.
US07901889B2
Methods, systems and compositions where a target nucleic acid includes a registration sequence disposed therein for identification of the number or relative position of determined sequence from the template sequence. Particularly preferred aspects include a registration sequence in a circular template nucleic acid sequence which is, in turn, used in sequence by incorporation processes that rely upon template dependent, polymerase mediated primer extension in the identification of the sequence of the template.
US07901886B2
The invention relates to an extraction method for isolating target molecules from a sample using a microfluidic carrier.
US07901885B2
Genes, SNP markers and haplotypes of susceptibility or predisposition to T2D and subdiagnosis of T2D and related medical conditions are disclosed. Methods for diagnosis, prediction of clinical course and efficacy of treatments for T2D, obesity and related phenotypes using polymorphisms in the risk genes are also disclosed. The genes, gene products and agents of the invention are also useful for monitoring the effectiveness of prevention and treatment of T2D and related traits. Kits are also provided for the diagnosis, selecting treatment and assessing prognosis of T2D. Novel methods for prevention and treatment of metabolic diseases such as T2D based on the disclosed T2D genes, polypeptides and related pathways are also disclosed.
US07901878B2
Provided are screening assays for identifying and evaluating compounds with antioxidant and/or antiproliferative activities.
US07901877B2
The present invention provides genetic markers, SOX5 and SPARC, for distant metastasis and poor prognosis of detection of the high risk potential for cancer patients. In addition, the present invention also provides a method to predict the risk potential for cancer patients with distant metastasis and poor prognosis. This method comprises obtaining a tissue sample from a patient; evaluating the expression levels of the SOX5 and/or SPARC genetic markers in the sample; and comparing the expression levels of genetic markers with those of non-cancerous tissues. The patient is determined to have the high risk of distant metastasis or poor prognosis when the expression level of SOX5 is higher, or when the expression level of SPARC is lower, than that of non-cancerous tissue. Furthermore, the identified genetic marker SOX5 and/or SPARC can also be used for cancer targeted therapy, because down regulation of SOX5 and/or up regulation of SPARC expression in NOD-SCID can retard tumor growth and inhibit cell proliferation, migration, invasion and metastasis.
US07901874B2
A method of detecting proliferative diseases causing sclerosis, comprising measuring the expression of at least one substance selected from the group consisting of STAT3, phosphorylated STAT3, Smad1, phosphorylated Smad1, activin receptor-like kinase 1, activin receptor-like kinase 3 and bone morphogenetic proteins in a biological sample. A kit therefor. A prophylactic and/or therapeutic agent for proliferative diseases causing sclerosis, comprising as an active ingredient a substance having an inhibitory effect on the expression of at least one substance selected from the group consisting of STAT3, phosphorylated STAT3, Smad1 and phosphorylated Smad1. A method of identifying substances effective in preventing and/or treating proliferative diseases causing sclerosis, comprising judging whether or not a test substance inhibits the expression of at least one substance selected from the group consisting of STAT3, phosphorylated STAT3, Smad1 and phosphorylated Smad1. A kit therefor.
US07901863B2
A photosensitive resin composition for a laser engravable printing substrate, comprising resin (a) having a polymerizable unsaturated group whose number average molecular weight is in the range of 1000 to 20×104, organic compound (b) having a polymerizable unsaturated group whose number average molecular weight is <1000 and organosilicon compound (c) having at least one Si—O bond in each molecule and having no polymerizable unsaturated group in molecules, wherein the content of organosilicon compound (c) is in the range of 0.1 to 10 wt. % based on the whole of photosensitive resin composition.
US07901857B2
The present invention provides a toner for developing an electrostatic latent image comprising at least a core layer including at least a coloring agent and a first binder resin, and a shell layer for covering the core layer and including a second binder resin, wherein two local maximum values of the tangent loss (tan δ) of the dynamic visco-elasticity are present in a temperature range of 90° C. or less, with one of the local maximum values present in a range of less than 60° C., and the other local maximum value present in a range of 60° C. or more and 90° C. or less.Moreover, a production method for the toner for developing an electrostatic latent image, a developer for developing an electrostatic latent image, using the toner, and an image forming method are provided.
US07901856B2
A photoconductor that includes, for example, a supporting substrate, a photogenerating layer, and at least one charge transport layer comprised of at least one charge transport component, and where the photogenerating layer contains an ammonium salt, an imidazolium salt, or mixtures thereof.
US07901854B2
A wafer edge exposure unit comprises a chuck for supporting a wafer. The chuck is rotatable about a central axis. A plurality of light sources are positioned or movably positionable with a common radial distance from the axis of the rotatable chuck, each light source configured to direct exposure light on a respective edge portion of the wafer simultaneously.
US07901853B2
A pattern prediction method according to an embodiment includes: predicting a second pattern shape from a first pattern shape by using a conversion function and a conversion difference residual error amount function, wherein; the conversion function makes the connection between the first pattern formed by a first step and the second pattern formed by a second step following the first step based on contour shapes of the first pattern and the second pattern, and the conversion difference residual error amount function makes the connection between a residual error amount between a predicted shape of the second pattern obtained from the conversion function and the second pattern shape obtained by actually using the second step, and factors other than the contour shapes of the first pattern and the second pattern.
US07901851B2
A dye polymer prepared by polymerizing one or more pigment monomer represented by formula (I), or a dye polymer prepared by copolymerizing one or more pigment monomer represented by formula (I) and one or more monomer having one ethylene group.[R1: H, chlorine atom, alkyl group, or aryl group; L1: —N(R2)C(═O)—, —OC(═O)—, —C(═O)N(R2)—, —C(═O)O—, or a group represented by formula (II), formula (III), or formula (IV); R2: H, alkyl group, aryl group, or hetero cyclic group; L2: divalent coupler for coupling L1 and Dye; n=0 or 1, m=0 or 1; Dye: pigment residue]
US07901841B2
In a photolithographic pellicle for dustproof protection of a photomask for photolithographic patterning by mounting thereon with the aid of a pressure-sensitive adhesive layer on one end surface of the pellicle frame, the adverse influence on the flatness of the photomask caused by mounting the pellicle can be minimized when the thickness of the pressure-sensitive adhesive layer is 0.4 mm or larger or when the elastic modulus of the layer does not exceed 0.5 MPa.
US07901838B2
A method of construction of an electrochemical interconnect plate, the method comprising the steps of: (a) etching predetermined fluid flow channels in a first conductive sheet; and (b) coating the first conductive sheet with a corrosion resistant layer of nickel and tin.
US07901832B2
A fuel cell assembly is disclosed that utilizes a fuel cell plate having hydrophobic portions adjacent an inlet and an outlet formed therein, and a hydrophilic portion formed in the flow channels of the fuel cell plate adjacent the hydrophobic portions, wherein the hydrophilic portion and the hydrophobic portion facilitate the transport of liquid water from the fuel cell plate.
US07901828B2
A fuel cell is provided with a cell laminated body in which a plurality of cells are laminated, an end plate arranged outside the cell laminated body in a laminating direction; and a spring module which is arranged between the cell laminated body and the end plate so as to adjust a compressive load to the cell laminated body. The spring module is provided with coil springs which are arranged between an upper plate and a lower plate so as to separate the upper plate and the lower plate from each other by an elastic force. The spring module is provided with a plurality of load display sections having display shafts which are fixed to the lower plate, inserted into through holes of the upper plate and protrude from the outer surface of the upper plate on an end plate side.
US07901827B2
A fuel cell apparatus including a reaction unit for performing a chemical reaction, at least one fan for providing an airflow, and an airflow guiding device is provided. The airflow guiding device is connected to the fan and the reaction unit. The airflow guiding device includes an airflow rectification segment and a first airflow separation segment. The airflow rectification segment is connected to the fan and has one flow channel. The first airflow separation segment is connected to the airflow rectification segment and disposed between the airflow rectification segment and the reaction unit. A number of flow channels inside the first airflow separation segment is N1, where N1 is a positive integer and N1>1.
US07901808B2
One embodiment of the present subject matter includes a battery having a stack of substantially planar battery electrodes, the stack including a first electrode including a first tab, and a second electrode including a second tab, with the first tab electrically connected to the second tab. The embodiment includes a first separator layer and a second separator layer sandwiching the first electrode, with the edges of the first separator layer and the second separator connected with a weld, the first separator layer and the second separator layer defining an interior space in which the first electrode is disposed, with the first tab extending outside the interior space. The embodiment includes an battery housing having electrolyte disposed therein, the housing including at least a first aperture and a feedthrough aperture; a lid conformed and sealed to the first aperture; and a feedthrough conformed and sealed to the feedthrough aperture.
US07901801B2
According to one embodiment, a perpendicular magnetic recording medium includes a substrate, and a first magnetic layer and a second magnetic layer formed on the substrate, in which supposing that, for the first and second magnetic layers, respectively, uniaxial magnetic anisotropy constants are Ku1 and Ku2, saturation magnetizations are Ms1 and Ms2, anisotropic magnetic fields are Hk1 and Hk2 and the thicknesses are t1 and t2, then following conditions are satisfied that Ku1 and Ku2 are 3×106 erg/cc or more, Ms1 is smaller than Ms2, Hk1 is larger than Hk2 and t1 is larger than t2.
US07901798B2
Ceramic materials with relatively high resistance to wetting by various liquids, such as water, are presented, along with articles made with these materials, methods for making these articles and materials, and methods for protecting articles using coatings made from these materials. One particular embodiment is an article that comprises a coating having a surface connected porosity content of up to about 5 percent by volume. The coating comprises a material that comprises a primary oxide and a secondary oxide, wherein (i) the primary oxide comprises a cation selected from the group consisting of cerium, praseodymium, terbium, and hafnium, and (ii) the secondary oxide comprises a cation selected from the group consisting of the rare earth elements, yttrium, and scandium. The material is transparent to electromagnetic radiation of at least one type selected from the group consisting of ultraviolet radiation, visible light, and infrared radiation.
US07901786B2
A method for manufacturing an ultra-hydrophilic thin film coated metal product having excellent hydrophilic properties, aging properties and corrosion resistance in an industrial scale production wherein the thin film includes an HMDSO anticorrosive thin film selectively formed on both surfaces of a metal substrate sheet, and an ultra-hydrophilic Ti—O—(C)—(H) group compound thin film is coated on the anticorrosive thin film. The metal substrate sheet is mechanically processed into a target shape.
US07901784B2
An optical waveguide in which a groove is formed on the top surface of a substrate used as a lower clad and a core is formed in the groove, characterized in that the core is formed in such a way that the top face of the core within the groove is at a lower level than the top face of the substrate, and an upper clad may also be provided on the core, and the core is preferably formed from an organic-inorganic hybrid material.
US07901778B2
A multilayer polymer film includes first and second polymer layers. The first polymer layer includes a first ultraviolet radiation absorber. The second polymer layer overlies the first polymer layer and includes a second ultraviolet radiation absorber. The first ultraviolet radiation absorber has a peak absorbtivity wavelength less than 300 nm and the second ultraviolet radiation absorber has a peak absorbtivity wavelength greater than 300 nm.
US07901777B2
A coated article comprising a substrate having a plastic surface and adhered thereto an organometallic film in which the metal has f electron orbitals or is niobium is disclosed. Also disclosed are methods for applying organometallic films to substrates and the organometallic films themselves.
US07901774B2
The present invention relates to an inorganic dental powder, coated with at least one layer comprising inorganic and/or organic substances or consisting thereof, and to a process for its preparation.
US07901767B2
A method for producing a laminate having a structure of an organic layer and an inorganic layer laminated thereon, which comprises polymerizing a mixture that contains a monomer of the following formula (1) wherein m is 2 and a monomer of the following formula (1) wherein m is 3 or more, thereby forming the organic layer: wherein R1 represents a hydrogen atom or a methyl group; and L represents an m-valent linking group.
US07901765B2
A laminate product comprising a foam core having a pair of opposed major surfaces and a cover layer secured with respect to each major surface is described. The cover layer is essentially free of fibreglass and comprises a polymeric substrate having disposed therein a plurality of porous material layers. It has been found that the use of fibreglass as a reinforcing material (and other sheet materials having a tensile modulus of greater than or equal to about 0.5 GPa when measured pursuant to ASTM D 5034) in a foam laminate product can be avoided by using a porous material layer in place of the fibreglass. In a preferred embodiment of the invention, the porous material layer has a tensile modulus less than that of fibreglass mat yet can be used to produce a foam laminate product having significantly higher strength properties.
US07901764B2
An object of the present invention is to provide a multi-layered polylactic acid resin foamed body of a crystalline polylactic acid resin which has good appearance and excellent mechanical strength such as bending strength and compressive strength and which is capable of being imparted with excellent heat resistance, and to provide a multi-layered polylactic acid resin foamed molded article having excellent appearance, heat resistance and mechanical strengh. The multi-layered polylactic acid resien foamed body of the present invention is a laminate having a polylactic acid resin foamed layer and a thermoplastic resin layer provided at least one side of the foamed layer, wherein the foamed layer has a cell shape satisfying specific conditions, wherein the difference (ΔHendo:2° C./min−ΔHexo:2° C./min) between an endothermic calorific value (ΔHendo:2° C./min) and an exothermic calorific value (ΔHexo:2° C./min) of the foamed layer as measured by heat flux differential scanning calorimetry at a heating rate of 2° C./min is less than 40 J/g, and wherein the endothermic calorific value (ΔHendo:2° C./min) is at least 10 J/g and the exothermic calorific value (ΔHexo:2° C./min) is at least 3 J/g.
US07901760B2
A laminate assembly comprises a base layer, a substantially transparent inclusion layer disposed above the base layer and having a plurality of included objects disposed within the inclusion layer, and a substantially transparent top layer disposed above the inclusion layer. The base layer, inclusion layer, and top layer are formed in succession.
US07901754B2
The present invention is a system and related device for an easy and simple hooking of graphic representations, for example paintings and prints. The representations are made on a support of thin and soft material, for example cloth or leather goods, which can be applied, in an interchangeable way, on any kind of clothes, fittings for clothes, furnishings and interior decorations.
US07901749B2
The invention relates to the discovery that pre-treating mineral oxide particles with a silylated polymeric coupling agent prior to suspending the particles in a binder polymer increases the crack resistance and adhesion of particles to a inkjet printing substrate such as paper sheets. Such pretreatment also reduces the amount of binder needed to achieve acceptable performance, leading to improvements in production speed and image quality.
US07901745B2
3,4-Dicarboxy-1,2,3,4-tetrahydro-6-t-butyl-1-naphthalene-succinic dianhydride is provided. The tetracarboxylic dianhydride is represented by Formula 1, which is described in the specification. Further provided is a liquid crystal aligning agent comprising a polyimide prepared using the tetracarboxylic dianhydride and a solvent. Further provided is a liquid crystal alignment layer formed using the liquid crystal aligning agent. The liquid crystal alignment layer exhibits excellent electro-optical properties and good processability in terms of printability.
US07901742B2
A method for forming a metal oxide fine particle layer, by which a metal oxide fine particle layer having uniformity and excellent in adhesion, abrasion resistance, strength, etc. can be formed easily compared with the conventional plating method, CVD method, liquid coating method, electrodeposition method or the like. The method comprises immersing a conductive substrate in a dispersion of metal oxide fine particles and fibrous fine particles and applying a direct-current voltage to the conductive substrate and the dispersion. The fibrous fine particles have a length (L) of 50 nm to 10 μm, a diameter (D) of 10 nm to 2 μm and an aspect ratio (L)/(D) of 5 to 1,000. The content of the fibrous fine particles in the dispersion is in the range of 0.1 to 20% by weight in terms of solids content, based on the metal oxide fine particles.
US07901738B2
A method for forming an electrode for a battery includes the step of forming a porous layer on the surface of an electrode hoop formed at its surface with a mixture layer containing an active material. The porous layer is formed in the following manner: A gravure roll is rotated oppositely to the direction of movement of the electrode hoop while being allowed to abut against the surface of the moving electrode hoop, thereby applying a coating fluid serving as a precursor of the porous layer to the surface of the electrode hoop. A plurality of grooves formed in the circumferential surface of the gravure roll extend in parallel in oblique directions against the rotation direction of the gravure roll from the central line of the circumferential surface to the outer edges of the circumferential surface so as to be arranged in a symmetrical manner relative to the central line.
US07901734B2
The method manufactures a nozzle plate having nozzle orifices for ejecting liquid droplets. The method comprises: a hole forming step of forming holes in a nozzle forming substrate, each of the holes passing through the nozzle forming substrate and having openings on a surface of a liquid droplet ejection side and a surface of a side opposite thereto of the nozzle forming substrate, the holes having a larger diameter than the nozzle orifices; a liquid-philic film forming step of forming a liquid-philic film on inner walls of the holes, the liquid-philic film blocking at least a portion of each of the holes; a liquid-repelling film forming step of forming a liquid-repelling film on the surface of the liquid droplet ejection side of the nozzle forming substrate, after performing the liquid-philic film forming step; and a nozzle orifice forming step of forming the nozzle orifices in the holes that are filled with the liquid-repelling film, after performing the liquid-repelling film forming step.
US07901733B2
A method of making fabrics having first and second surfaces that exhibit different performance characteristics by virtue of having been treated with different chemical treatments is described. In addition, fabrics having first and second surfaces that exhibit different performance characteristics, such as one surface exhibiting oil and water repellency and optionally, soil release characteristics, and the opposite surface exhibits moisture transport characteristics.
US07901731B2
Methods, treatment compositions and treatment systems are disclosed for forming a detachable and renewable coating on a receptive surface by a process of applying a treatment composition comprising a plurality of hydrophobically modified fumed silica particles colloidally dispersed in a volatile solvent; allowing the volatile solvent to evaporate; and thereby depositing a protective coating on the receptive surface consisting of a layer of the hydrophobically modified particles, which provide a substantially transparent coating with dirt- and water-repellency properties that effectively shed dry particulate soils as well as water from the treated surface or treated article bearing a receptive surface. The methods, treatment compositions and treatment systems employing the hydrophobically modified fumed silica particle are particularly useful in providing nearly invisible detachable coatings and treated articles featuring surface protective benefits including dirt- and water-repellency, self-cleaning with water, and easier cleaning benefits when applied to a variety of automotive and home surfaces, both interior and exterior, including articles and materials such as metals, painted materials, sealed materials, plastics and polymeric articles, wood, textiles and the like.
US07901725B2
The present invention discloses novel methods of using Phleum spp. seeds, especially Timothy grass (P. pratense L.) seeds, for making gluten-free food products and the food products produced using such methods.
US07901718B2
A process for the extraction, purification and enzymatic modification of β-conglycinin α′ subunit, wherein β-conglycinin is selectively extracted from ground, defatted soy, then precipitated by treatment with aqueous ethanol; the enriched fraction is then subjected to Metal Affinity Chromatography (MAC) in denaturant conditions to obtain the α′ subunit, which is treated with chymotrypsin, then subjected to a further MAC to recover the amino-terminal region of this polypeptide (MW 28,000 Da).
US07901710B2
A nutritional supplement for use in physiologically stressful conditions comprising vitamin A, vitamin E, vitamin D3, vitamin C, vitamin B1, riboflavin, niacin, folic acid, vitamin B6, biotin, pantothenic acid, vitamin B12, magnesium, zinc, selenium, chromium, copper, iron, alpha lipoic acid, lutein, and lycopene is disclosed.
US07901709B2
A liposome contains an active agent and has a gel-phase lipid bilayer membrane comprising phospholipid and a surface active agent. The phospholipids are the primary lipid source for the lipid bilayer membrane and the surface active agent is contained in the bilayer membrane in an amount sufficient to increase the percentage of active agent released at the phase transition temperature of the lipid bilayer, compared to that which would occur in the absence of the surface active agent. The surface active agent is present in the lipid bilayer membrane so as to not destabilize the membrane in the gel phase.
US07901703B2
Implantable medical devices including polycationic peptide coatings are disclosed.
US07901702B2
The present invention is directed to novel implantable or insertable medical devices that provide controlled release of a therapeutic agent. According to an embodiment of the present invention, a therapeutic-agent-releasing medical device is provided, which comprises: (a) an implantable or insertable medical device; (b) a release layer disposed over at least a portion of the implantable or insertable medical device; and (c) a therapeutic agent. The release layer comprises a styrene copolymer and at least one additional polymer. The release layer regulates the rate of release of the therapeutic agent from the medical device upon implantation or insertion of the device into a patient. The present invention is also directed to methods of forming the above implantable or insertable medical devices, methods of administering a therapeutic agent to a patient using such devices, and methods of modulating the release of therapeutic agent from such devices.
US07901691B2
A novel chimeric protein of rabies virus designed to express a chimeric G protein at a high level in transgenic plants. A gene was also designed and chemically synthesised to encode the chimeric G protein and expressed at high level in plant tissue. The gene was expressed in transgenic tobacco plants to examine its therapeutic efficacy against infection by rabies virus. The chimeric G protein was enriched in plant membranes. The BalbC mice were immunised with the plant leaf expressed G-protein. Plant derived chimeric G protein elicited higher immune response as compared to the commercial vaccine. The mice displayed protective immunity when they were challenged with live virus. Chimeric G protein expressed at high level in plant leaves was demonstrated to function as a commercially valuable subunit vaccine against rabies virus infection.
US07901678B2
The present invention provides pharmaceutical compositions composing, as an active ingredient, a substance capable of activating the γ chain of Fc receptors (FcRγ) (provided that the substance is not an immunoglobulin for intravenous injection), and agents for stimulating myelinogenesis. The invention also provides agents for stimulating the differentiation of oligodendroglial precursor cells, agents for activating Fyn tyrosine kinase, and agents for stimulating the expression of myelin basic protein, all comprising a substance capable of activating FcRγ as an active ingredient. Further, the invention provides a method of detecting myelinogenetic oligodendroglias or precursor cells thereof which comprises using the expression of FcRγ in oligodendroglias or precursor cells thereof as an indicator.
US07901676B2
A therapeutic composition and a method for rheumatoid arthritis is described. The composition comprises purified beta-glucuronidase at a concentration of between 200 and 10,000 Fishman units/ml and purified collagen at a concentration of between 0.5 and 2.5 mg/ml. The composition is administered by transdermal infusion or intradermal injection.
US07901666B1
The invention discloses a pharmaceutical composition for treating a subject comprising two or more bioactive nanoparticles, thus treating the subject by co-administering the bioactive nanoparticles to the subject, wherein a first and a second bioactive nanoparticles comprise a shell portion that is dominated by positively charged chitosan, a core portion that contains negatively charged substrate, and at least a first bioactive agent in the first nanoparticle and a second bioactive agent in the second nanoparticle.
US07901660B2
A quaternary oxide includes a dopant metal, a dopant nonmetal, titanium, and oxygen. The atomic ratio of titanium, oxygen and dopant nonmetal may be 1:0.5-1.99:0.01-1.5. Quaternary oxides may be used in catalytic compositions, in coatings for disinfecting surfaces and in coatings for self-cleaning surfaces. A method of making a quaternary oxide includes combining ingredients including a titanium source, a dopant nonmetal source, a dopant metal salt, and a polar organic solvent to form a reaction mixture; and heating the reaction mixture.
US07901654B2
Methods, processes, and apparatuses for the large scale synthesis of single-walled carbon nanotubes having small diameters are provided. Metal catalysts having small diameter and narrow distribution of particle sizes are prepared and continuously injected as aerosols into a reactor. The metal catalysts are supported on supports that are substantially free of carbon, and the reactor is configured to control the flow of the gases such that the reaction time and contact of the reactants with the reactor walls can be controlled. Single-walled carbon nanotubes can be continuously synthesized at a large scale and with high yields, and with small diameters and with narrow diameter ranges.
US07901651B2
Provided are a method of preparing a zinc silicate-based phosphor and a zinc silicate-based phosphor prepared using the method. The method includes: (a) preparing a solution including a Zn precursor compound and a Si precursor compound; (b) adding a coprecipitant to the solution to form precipitation; and (c) heat treating the solution in which the precipitation is formed to synthesize zinc silicate (Zn2SiO4), wherein a solvent of the solution including the Zn precursor compound and the Si precursor compound includes at least one selected from the group consisting of ethanol, methanol, 1-propanol, 2-propanol, 1-butanol, 2-butanol, 1-pentanol, 2-pentanol, 3-pentanol, 1-hexanol, and 1-heptanol, and hydrazine is used as the coprecipitant.
US07901644B2
Processes are described for the extraction and recovery of alkali metal from the char that results from catalytic gasification of a carbonaceous material. Among other steps, the processes of the invention include a hydrothermal leaching step in which a slurry of insoluble particulate comprising insoluble alkali metal compounds is treated with carbon dioxide and steam at elevated temperatures and pressures to effect the conversion of insoluble alkali metal compounds to soluble alkali metal compounds. Further, processes are described for the catalytic gasification of a carbonaceous material where a substantial portion of alkali metal is extracted and recovered from the char that results from the catalytic gasification process.
US07901643B2
A sensor unit for use in a surface plasmon resonance (SPR) assay includes a flow channel device, which causes a sample fluid of a sample to flow on a sensing surface lying on a prism. The flow channel device includes a rigid device body part having an opposing surface positioned opposite to the sensing surface. A flow recess is formed in the opposing surface, closed by the prism to constitute a flow channel, for covering the sensing surface. A sealant portion is overlaid on an edge portion of the opposing surface and the flow recess in the device body part. The sealant portion tightens closing between the device body part and the prism. Also, the sealant portion projects over the opposing surface of the device body part in a state before contacting the prism. In addition, the sealant portion is formed from material having a small non-specific adsorption.
US07901639B2
There is provided a reaction apparatus which is capable of keeping the pressure inside the reactor and is applicable to various fields. This reaction apparatus comprises: a raw material tank (2) for storing a raw material; a high-pressure pump (3) communicated with the raw material tank (2) and designed to deliver the raw material therefrom; a reactor (1) which is disposed on the downstream side of the high-pressure pump (3) and designed to be supplied with the raw material in a compressed state; a heating bath (11) for heating the reactor (1) to promote a reaction; and a product tank (7) for receiving and recovering a product; wherein the reaction apparatus is further equipped with an inlet port which is interposed between the heating bath (11) and the product tank (7), and with an injection pump (6) for injecting an injecting liquid through the inlet port, whereby a pressure of product flowing into the product tank (7) is enabled to be reduced by making use of the flow rate of the injecting liquid.
US07901636B2
Disclosed is an optimized process and apparatus for more efficiently and economically carrying out the liquid-phase oxidation of an oxidizable compound. Such liquid-phase oxidation is carried out in a bubble column reactor that provides for a highly efficient reaction at relatively low temperatures. When the oxidized compound is para-xylene and the product from the oxidation reaction is crude terephthalic acid (CTA), such CTA product can be purified and separated by more economical techniques than could be employed if the CTA were formed by a conventional high-temperature oxidation process.
US07901631B2
A unit for measurement of absorbance using a microchip has a microchip with a continuous cavity, a sample chamber, a reagent chamber, a reagent mixing chamber and a chamber for measuring absorbance, which is arranged in a straight line in the area of the continuous cavity. The microchip is located in a chip holder which has a capillary part which is arranged such that the light used to measure absorbance is delivered through the capillary part to the chamber for measuring absorbance, the capillary part having a smaller opening diameter than the diameter of the cross section which is perpendicular to the optical axis of the chamber for measuring absorbance.
US07901628B2
A method for fractionating a sample solution includes the steps of setting a first mass spectrometry condition and mass range information; setting a second mass spectrometry condition and mass range information; executing a mass scan by the mass spectrum acquisition portion under the first mass spectrometry condition and obtaining first mass spectrum data; extracting first chromatogram data from the first mass spectrum data based on the first mass range information; executing a mass scan by the mass spectrum acquisition portion under the second mass spectrometry condition to obtain second mass spectrum data; extracting second chromatogram data from the second mass spectrum data based on the second mass range information; switching the first and second spectrometry conditions and repeating the mass scan cyclically; adding the first and second chromatograph data to obtain a chromatogram data; and operating the fraction collector based on the chromatogram data.
US07901616B2
Method of building a direct smelting plant comprising a metal smelting vessel (11) and ancillary plant components such as the components of a hot air supply station (24), an offgas treatment station (32), a solids feed station (41), a hot metal desulphurization station (47) and hot metal and slag launders extending from the smelting vessel (11). The ring track (53) of a ringer crane (51) is installed in front of location at which vessel (11) is to be installed. Crane boom (54) is laid out along elongate stretch of the building site which becomes a corridor (60) between major ancillary components when plant is fully erected. Boom (54) is connected to crane carriage (52) and hoisted to provide high lift capacity over a ground area embracing proposed site of vessel (11) and ancillary components. Prefabricated components are then lifted by crane (51) into appropriate position for final installation. After installation is completed boom (54) is laid down along corridor (60) and crane (51) is dismantled and removed, leaving corridor (60) as an access laneway.
US07901609B2
A process for the preparation of a plane-parallel structure (a platelet-shaped body, or flake), comprising at least one dielectric layer consisting of oxides of one or more metal selected from groups 3 to 15 of the periodic table, which method comprises subjecting one or more precursors of one or more desired metal oxides and an acidic catalyst to microwave radiation to form a metal oxide layer on a substrate; and separating the resulting metal oxide layer from the substrate.
US07901605B2
The liquid crystal display device of the present invention comprises first and second substrates; a first alignment layer on the first substrate, wherein the first alignment layer includes (spacer S is oxygen, m=10˜10,000), the functional group R includes photo-sensitive constituents and/or non-photo-sensitive constituents, the photo-sensitive constituent includes a material selected from the group consisting of cinnamoyl derivatives, the non-photo-sensitive constituent includes a material selected from the group consisting of CnH2n, CnH2n+1, CnH2nOH, COCnH2n+1, COCnH2n, CnH2n+1−xFx, CnH2n−(x−1)F(x−1), CnH2n−xFxOH, COCnH2n+1−xFx (n=1˜10, x=1˜2n+1), and a combination thereof; and a liquid crystal layer between the first and second substrates.
US07901579B2
A configuration of a blood microtubular filter/dialyzer used in many kinds of renal replacement therapy systems can provide a highly effective mechanism for removing air from the blood circuit of such systems. Air is removed from an outlet header space of the filter avoiding the need for a bubble trap or settling chamber such as a drip chamber.
US07901575B2
A simple device, skimmer or utensil perfect for removing unwanted fat, impurities or foam from excess starch accumulated on the surface of soups, stocks, sauces, stews, or boiling pasta; wherein the skimmer is slowly inserted into the cooked liquid and by gently rotating its handle back and forth and gradually dipping the plate into the liquid, the fat, grease, or unwanted foam is spilled onto its holding plate; thus, removing from the cooked food unhealthy fat and/or other unwanted impurities.
US07901562B2
A deterioration detection apparatus for an oxygen sensor is able to detect an abnormality of the oxygen sensor constantly with high precision, without being affected by the temperature characteristic of the element impedance. The apparatus applies a voltage V to the oxygen sensor, and calculates an element impedance real value Rsr=V/1 of a sensor element based on the applied voltage and the current I caused to flow by the voltage. The apparatus calculates an element temperature estimated value Tex of the oxygen sensor from a factor that affects the temperature of the oxygen sensor. The apparatus determines whether the oxygen sensor has an abnormality on the basis of whether the relationship between the element impedance real value Rsr and the element temperature estimated value Tex can be regarded as a relationship that agrees with a normal temperature characteristic.
US07901558B2
Described is a process for the separation of a sample mixture for analytical reason based on two-dimensional gel electrophoresis. The method is involving a first separation in a first gel strip on the basis of isoelectric points and a second separation in a second gel on the basis of molecular size. When starting the separation in the second dimension the buffer solution for transferring the compounds separated in the first dimension into the second dimension gel is containing sodium dodecyl-sulfate (SDS) and by applying an electric field the SDS migrates electrokinetically into the first gel strip, and the compounds are being complexed simultaneously with SDS.
US07901550B2
A plating apparatus can form a plated film having a uniform thickness over the entire surface of a substrate without a change of members. The plating apparatus includes a substrate holder, a cathode contact for contacting a conductive film formed on the substrate so that the conductive film serves as a cathode, a ring-shaped seal member for covering the cathode contact and bringing its inner circumferential portion into contact with the peripheral portion of the substrate to seal the peripheral portion of the substrate, an anode disposed so as to face the conductive film formed on the substrate, and an auxiliary cathode disposed with respect to the seal member such that at least part of the auxiliary cathode is exposed on a surface of the seal member. Plating is carried out by bringing the conductive film, the anode and the auxiliary cathode into contact with a plating solution.
US07901548B2
The invention relates to an electrolytic cell for the production of chlorine from an aqueous alkali halide solution, which mainly consists of two semi-shells, an anode, a cathode and an ion exchange membrane arranged between the electrodes. Spacer elements are arranged between the ion-exchange membrane and the electrodes for fixing the membrane in position and distributing the compressive forces, made of electrically conductive and corrosion-resistant material on at least one side of the membrane.
US07901546B2
The present invention includes systems, methods and apparatus for continuously, independently and in some cases remotely monitoring the operation of a current interrupter used to test a cathodic protection system, or the cathodic protection system itself, for verification of proper operation. Embodiments of the invention include electronic devices that may be temporarily attached to a current interrupter that is being used to test a cathodic protection system, or directly to the cathodic protection system itself. Embodiments of the invention monitor the activity of an interrupter by sampling the output (voltage and time) to identify the cycle(s) of the interrupter. The invention provides truly independent verification since it does not need to know in advance the sequence or cycle times of the current interrupter being monitored. The information obtained by the invention is output so that it may be provided to a user, displayed, downloaded or stored for future reference.
US07901538B2
A transparent conductive multi-layer structure having a smooth base material 1, a transparent conductive layer 2 formed on the smooth base material 1 by coating, an auxiliary electrode layer 3 formed in a pattern on the transparent conductive layer 2, and a transparent substrate 5 joined to the transparent conductive layer 2 and auxiliary electrode layer 3 through an adhesive layer 4. On a smooth peeled-off surface of the transparent conductive layer 2 from which the smooth base material 1 has been peeled off, various devices are formed to set up devices such as a dye-sensitized solar cell and an organic electroluminescent device.
US07901536B2
Conductive traces and patterns of same are used to bond components together via electromagnetic radiation. Each conductive trace is configured to resonate and heat up when irradiated with electromagnetic radiation, such as microwave energy and/or RF energy, having a wavelength that is about 2.3 times the length of the conductive trace. The conductive traces may be arranged in a pattern to uniformly heat a target area of a substrate or other component to a selected temperature when irradiated with electromagnetic radiation.
US07901534B2
Diapers are made with substantial reduction of waste using a composite web of diaper main body material having a liquid impervious outer layer, a liquid pervious inner layer and an absorbent intermediate layer there between. The composite web has an indeterminate longitudinal extent substantially intact and uncut with parallel lateral side edge margins for substantially the entire web length. An independent web of diaper tab material is cut into discrete tab sections of predetermined mating shapes with substantially no unused waste material. The tab sections are affixed to the opposite edge margins of, and at regular longitudinal spacings along, the composite web. The composite web is cut transversely at regular longitudinal intervals there along corresponding to the spacings of the tab sections to produce discrete diapers each having a generally rectangular main body and four tabs at the respective corners of the main body.
US07901532B2
The present invention relates to a system and a method of improving the debonding of two or more surfaces together. The invention utilises thermoexpanadable microspheres and thermal energy to debond interfaces in an adhesive system or as vehicle carriers. It also discloses a method of curing the adhesive system prior to the debonding step so that the same adhesive system may be used for both phases. It is especially useful in the automotive industry for end of vehicle life dismantling.
US07901530B2
A method of manufacturing a fabric seam in a fabric for use as papermachine clothing, the fabric having loops at each of the fabric's transverse ends adapted for interconnection by way of a pintle to make the fabric endless, including the steps of bringing the ends into end-to-end disposition in order to interdigitate the loops, inserting a pintle in the interdigitated loops, heat setting to fix base yarns and the loops of the fabric in place, inserting at least one stuffer yarn, at least a part of which includes a low melt component, into selected void areas in the loops adjacent the pintle, adhering at least one batt layer to the seam by needling, and further heat setting to at least partially melt the stuffer yarn such that it deforms to substantially take on the shape of the void areas at the pintle joint, to bind fibers of the batt needled into the void areas and to bind adjacent yarns of the fabric.
US07901527B2
Provided is a microchip manufacturing method by which a functional film is formed in a flow path channel and resin microchip substrates are bonded. The manufacturing method has a first step of forming SiO2 films (12, 22) representing the functional films on a surface having a flow path channel (11) of a microchip substrate (10) and on a surface having a flow path channel (21) of a microchip substrate (20) respectively; a second step of exfoliating the SiO2 films formed on the microchip substrates (10, 20) except the SiO2 films formed on the flow path channels (11, 21) by a cohesive member; and a third step of placing the microchip substrates (10, 20) one over another in such a way that the surfaces on which the flow path channels (11, 21) are formed face inside, and bonding the substrates by laser welding, ultrasonic wave welding or thermocompression bonding.
US07901525B2
A method for manufacturing a stent, includes the steps of winding stent wire around the outer surface of a longitudinal axis of a mandrel into a desired final shape that is polygonal in an elevation orthogonal to the longitudinal axis, and forming a stent by setting the wound stent wire in the desired polygonal final shape. The outside diameter of the stent formed will be in co-columnar apposition with a blood vessel in which it is implanted. The mandrel employed in the methods can have a multiple-sided outer surface and a longitudinal axis.
US07901524B1
Apparatus and associated methods for actuating variable stiffness material (VSM) structures and achieving deformation of the structures. The apparatus and the associated methods use internal embedded actuation elements and/or externally attached elements to the VSM structures to achieve the desired deformation. In particular, the actuation can be changed due to the variable stiffness nature of the materials. That is, the invention provides the ability to control the deformation of structures using local stiffness control over subregions of the component in addition to or in substitution for actuation. Furthermore, the invention exploits the variable stiffness properties of the VSM structures to enable new functionalities impossible to realize with conventional constant stiffness materials.
US07901522B2
An aluminium alloy having high mechanical strength and low quench sensitivity comprising 4.6 to 5.2 wt. % Zn, 2.6 to 3.0 wt. % Mg, 0.1 to 0.2 wt. % Cu, 0.05 to 0.2 wt. % Zr, max. 0.05 wt. % Mn, max. 0.05 wt. % Cr, max. 0.15 wt. % Fe, max. 0.15 wt. % Si, max. 0.10 wt. % Ti and aluminium as the remainder along with production related impurities, individually max. 0.05 wt. %, in total max. 0.15 wt. %. A process for producing plates having a thickness of more than 300 mm for manufacturing moulds for injection-moulding plastics is made up of the following steps: continuous casting the alloy into ingots having a thickness greater than 300 mm, heating the ingots to a temperature of 470 to 490° C. with a max. heating rate of 20° C./h between 170 and 410° C., homogenising the ingots for 10 to 14 h at a temperature of 470 to 490° C., cooling the ingots in still air to an intermediate temperature of 400-410° C., cooling the ingots by means of forced air cooling from the intermediate temperature of 400-410° C. to a temperature of less than 100° C., cooling the ingots to room temperature, artificially age-hardening the ingots at elevated temperature. The artificially age-hardened ingots can be employed for manufacturing moulds for injection-moulding plastics.
US07901516B2
The present invention is improved cleaning composition having at least one ketone, water, and a nonionic surfactant and a method of using the composition for cleaning organic residue.
US07901513B2
A wash cylinder or chamber for an automated cleaning station to clean an object or a person's body part includes nozzles on the interior of the cylinder, the nozzles of one embodiment comprising an increasing roll angle providing a novel spray pattern. Additionally, embodiments of the invention include fluid guidance and conveyance structures, angled nozzles, sealing structures, finger guards, nozzle ribs, wash chamber seating mechanisms and drains, and nozzle inlays having a plurality of nozzles. Also disclosed are methods of washing an object or body part using a wash cylinder or chamber and methods of assembling a wash cylinder or chamber.
US07901507B2
The present invention relates to a crystal of ACE protein. The present invention further relates to methods, processes, ACE modulators, pharmaceutical compositions and uses of ACE crystal and the structure coordinates thereof.
US07901505B2
A method of producing cementitious mixtures containing fly ash as one of the cementitious components, under air entrainment conditions. The method involves forming a mixture comprising water, cement, fly ash, optionally other cementitious materials, aggregate, conventional chemical admixtures, and an air entrainment agent and agitating the mixture to entrain air therein. Additionally, at least one sacrificial agent is also included in the mixture. The sacrificial agent is a material or mixture of materials that is not required to act as an air entrainment agent but interacts preferentially with components of the fly ash that otherwise neutralize, repress or depress the activity of the air entrainment agent. The invention includes cementitious mixtures and hardened concretes resulting from the method and fly ash treated with sacrificial agent, or air entrainment agent/sacrificial agent combinations, and processes for selecting suitable sacrificial agents.
US07901497B2
The present invention relates to an aqueous solution composition (water-based ink composition) containing a water-soluble naphthalocyanine coloring matter represented by the following formula (1): wherein, M represents a hydrogen atom, a metal atom, a metal oxide, a metal hydroxide or a metal halide, X represents a carbonyl group or a sulfonyl group, W1 to W4 are each independently a hydrogen atom, an ionic hydrophilic group or the like, at least one of W1 to W4 is a group other than a hydrogen atom, and n represents an integer number of 1 to 24, respectively, or a salt thereof, and a novel naphthalocyanine coloring matter, and said compound is useful as a near-infrared ray absorbent because it has a high absorption in the near-infrared region, and it is useful as a near-infrared ray absorbing water-based ink because it has an excellent storage stability in aqueous solution.
US07901496B2
Disclosed is a phase change ink composition comprising a phase change ink carrier and a colorant compound of the formula wherein Y is a hydrogen atom or a bromine atom, n is an integer of 0, 1, 2, 3, or 4, R1 is an alkylene group, an arylene group, an arylalkylene group, or an alkylarylene group, provided that no oxygen atom creates a linkage, X is —O— or —NR3— wherein R3 is a hydrogen atom, an alkyl group, an aryl group, an arylalkyl group, or an alkylaryl group, and R2 is a hydrogen atom, an alkyl group, an aryl group, an arylalkyl group, or an alkylaryl group.
US07901483B2
A process for producing titanium metal sponge from an exothermic reaction between titanium tetrachloride vapor and molten magnesium vapor, and reclaiming reactive metals from by-products of the exothermic reaction.
US07901478B2
Reservoir for a replacement fluid for a device, where the reservoir (3) is pre-filled with the desired quantity of the relevant replacement fluid (15) And where this reservoir is equipped with detachable coupling devices (29) which make it possible to mount and dismantle the reservoir (3) on the device (1) and where the reservoir (3), in its mounted state, serves as a changeable fluid.
US07901475B2
A diesel particulate filter assembly comprises a diesel particulate filter (DPF) and a heater assembly. The DPF filters a particulate from exhaust produced by an engine. The heater assembly has a first metallic layer that is applied to the DPF, a resistive layer that is applied to the first metallic layer, and a second metallic layer that is applied to the resistive layer. The second metallic layer is etched to form a plurality of zones.
US07901472B2
A composition for improving the combustion efficiency of an internal combustion Engine. The composition includes a mixture of a hydrocarbon fuel and an organometallic soap selected from among several cerium-containing and ferric compounds. The cerium-containing compound or compounds increase the energy released during combustion of the fuel. The ferric compound or compounds coat an interior wall of a combustion chamber of the internal combustion engine to increase the power output of the engine by reducing the accumulation of residues deposited on the interior wall which interfere with the combustion of fuel.
US07901470B2
The use of an effective concentration of a hydrocarbyl amine wherein the hydrocarbyl moiety has a number average molecular weight in the range 140 to 255 as an additive in an unleaded gasoline composition is provided containing a major proportion of a gasoline suitable for use in a spark ignition engine, for reducing injector nozzle fouling in a direct injection spark ignition engine. A method of operating a direct injection spark ignition engine is also provided.
US07901468B2
An inorganic solid electrolytic rechargeable battery having positive and negative electrodes and an inorganic electrolyte interposed therebetween is provided. The positive and negative electrodes each contain an active material layer and a current collector layer. The positive electrode collector layer or the negative electrode collector layer is a conductive metal oxide layer. The negative electrode active material layer contains lithium metal or lithium alloys. This negative active layer may optionally be made of a material which provides an operation voltage potential of the negative electrode to be more noble than 1.0 V with respect to the potential of a metallic lithium.
US07901464B2
A process for dyeing human keratin fibers in the presence of at least one oxidizing agent, comprising applying to the fibers at least one anhydrous composition (A) comprising at least one fatty substance and at least one surfactant, at least one composition (B) comprising at least one oxidizing agent, and at least one composition (C) comprising at least one dye chosen from direct and oxidation dyes, and at least one organic amine having a pKb at 25° C. of less than 12. The present disclosure also relates to a multi-compartment device containing, in separate compartments, the compositions (A), (B), and (C); and a method of making a ready-to-use composition. The present disclosure also relates to an anhydrous composition comprising at least one fatty substance, at least one surfactant, at least one dye, and at least one organic amine.
US07901460B2
Described are intervertebral disc implants that include an elastomeric polymer body, especially a hydrogel body, and a superelastic element. Also described are methods for making and using such implants.
US07901459B2
An artificial spinal joint for creating at least a portion of a coupling between a superior vertebra and an inferior vertebra is disclosed. The artificial spinal joint comprises a first arthroplasty half comprising a first articulating joint replacement component for placement in an intervertebral disc space between the superior and inferior vertebrae, a first posterior joint replacement component, and a first bridge component coupled between the first articulating joint replacement component and the first posterior joint replacement component. The artificial spinal joint further comprises a second arthroplasty half comprising a second articulating joint replacement component for placement in an intervertebral disc space between the superior and inferior vertebrae, a second posterior joint replacement component, and a second bridge component coupled between the second articulating joint replacement component and the second posterior joint replacement component. The first articulating joint replacement component is engaged with the second articulating joint replacement component.
US07901457B2
The invention is directed toward a cartilage repair assembly comprising a shaped allograft structure of subchondral bone with an integral overlying cartilage cap which is treated to remove cellular debris and proteoglycans and milled allograft cartilage in a bioabsorbable carrier. The shaped structure is dimensioned to fit in a drilled bore in a cartilage defect area so that either the shaped bone or the cartilage cap engage the side wall of the drilled bore in an interference fit and is in contact with a milled cartilage and biocompatible carrier mixture allowing cell transfer throughout the defect area. A method for inserting the shaped allograft structure into a cartilage defect area is also disclosed.
US07901448B2
The present invention is directed to an implantable vascular prosthesis configured for use in a wide range of applications, such as treating aneurysms, maintaining patency in a vessel, and providing controlled delivery of therapeutic agents to a vessel wall. The prosthesis comprises a helical body having a plurality of turns, wherein the proximal and distal edges of the turns of the prosthesis has a pattern that interdigitates when the prosthesis assumes the deployed configuration. The prosthesis optionally may comprise a radially expanding distal portion coupled to the helical body for facilitating placement of the prosthesis within a body vessel.
US07901441B2
A method of using an imaging catheter for activating a photodynamic agent is provided. The method generally includes four steps. First, an imaging catheter including a fiber optic cable is inserted within a body cavity or vessel. The fiber optic cable has a first end (e.g., proximal end) and a second end (e.g., distal end), and is configured to transmit electromagnetic irradiation from its first end to its second end and to transmit an image from its second end to its first end. Second, an image of a site of interest (e.g., the location of an aneurysm) within the body cavity or vessel is observed using the fiber optic cable. Third, a suitable photodynamic agent is applied to the site of interest. Fourth, the fiber optic cable is used to deliver a selected wavelength or wavelength range of electromagnetic energy to the site to thereby activate the photodynamic agent.
US07901440B2
A Static Compression Device (SC device) for active, measurable compression of a fusion graft by the surgeon at the time of surgery is disclosed. The SC device is attachable to adjacent vertebral bodies or other pieces of bone and has a device that applies compressive force to the adjacent vertebral bodies or pieces of bone to assist fusion according to Wolff's law. The SC device has a locking mechanism that maintains the compression applied at surgery, but prevents further compression (settling) from occurring after surgery. The SC device allows the surgeon the ability to compress a segment, measure the applied compression, and lock the segment in the compressed position. In one embodiment of the invention, the pressure is applied to the SC device through a compression device that applies a desired and measurable amount of force. In this embodiment, the combination of the SC device with a pressure applying and measuring device allows the surgeon more control over the force applied to a cervical, thoracic or lumbar implant than has previously been available. In the preferred embodiment, the SC device compresses two or more adjacent vertebrae across an adjacent bone graft to facilitate fusion of these vertebrae to treat pain produced by pressure from the disks between such vertebrae bulging and resulting in contact with and pressure on the spinal cord and adjacent nerve roots. In other embodiments, the SC device may be used to apply measurable compression across any type of bony interface (e.g. fractures) to facilitate union.
US07901438B2
A method and apparatus of limiting at least one degree of movement between a superior vertebrae and an inferior vertebrae of a patient includes advancing a distal end of a stabilization device into a pedicle of the inferior vertebrae. A proximal portion of the stabilization device is positioned such that the proximal portion limits at least one degree of movement between a superior vertebrae and an inferior vertebrae by contacting a surface of the superior vertebrae.
US07901433B2
A system (10) and associated method are provided for mechanically fixating a region of a skull to a portion of a spine. A plate (20) is provided to contact a region of the skull and be secured thereto. A spinal rod (22) is configured to extend from a location adjacent the plate (20) to a location adjacent at least one vertebra (30). A variable connection (24) is provided to secure the rod (22) to the plate (20). The variable connection (24) has a first mode wherein the relative position of the rod (22) to the plate (20) can be adjusted and a second mode wherein the relative position of the rod (22) to the plate (20) is locked at a particular value selected to maintain a desired curvature of the spine.
US07901428B2
Apparatus and methods are provided for use in sealing a vascular puncture site. The invention includes an introducer sheath with an integrated closure component. The closure component includes a fastener and an advanceable, deformable clip having a delivery configuration in which opposing sides do not contact one another, and a deployed configuration, in which the fastener causes opposing sides of the deformable clip to close towards one another. The clip is advanced along the sheath until it pierces opposing sides of a vessel wall at a puncture site. The clip is then deformed with the fastener to draw opposing sides of the puncture together, and the sheath is withdrawn to seal the wound. The clip and fastener preferably are bioabsorbable.
US07901426B2
An embolic protection device has a collapsible filter element (105) mounted on a carrier such as a guidewire (101). The filter element (105) collapses into the outer end of a catheter (118) for deployment and retrieval through a vascular system of a patient. The filter element (105) has a collapsible filter body with a proximal inlet end and a distal outlet end The proximal inlet end has inlet openings sized to allow blood and embolic material enter the filter body. The outlet end has outlet openings which allow through passage of blood but retain embolic material within the filter body. After use, the catheter (118) is movable along the guidewire (101) to engage the proximal end of the filter element and close the inlet openings before sliding over the fitter element from the proximal end to the distal end to progressively collapse the filter body on the guidewire (101) for retrieval. The filter element (105) may conveniently be mounted on a tubular sleeve (104) which is slidable and rotatable on the guidewire (101) between spaced-apart slops (106, 120) on the guidewire (101) which allows some manipulation of the guidewire independently of the filter when the fitter is in use.
US07901420B2
The present invention relates to a tissue clamp, a tool for grasping the clamp and a method of using the clamp for surgical procedures. The clamp has a fixture or fixtures positioned on the proximal end of the arms of the clamp so that a tool can be used by the surgeon to securely grasp the clamp during placement thereof on the vasculature or other tissue of the patient. The fixture can have a plurality of channels so that the user can select the angular orientation of the tool relative to the damp.
US07901396B2
A medical device delivery system and method of manufacture that includes an outer catheter, a first inner catheter insertable through the outer catheter, and a second inner catheter insertable through the first inner catheter and adapted to receive a guidewire extending there through. The first inner catheter includes a braided reinforcement layer and is adapted to receive an elongated medical device extending there through.
US07901395B2
A catheter may include a multiple lumen catheter tube, a hub attached to the catheter tube, and a first extension leg and a second extension leg attached to the hub. The multiple lumen catheter tube may include a longitudinal axis, an end, a first lumen, and a second lumen. The first lumen and the second lumen extend through the catheter tube along the longitudinal axis and each having an opening. The end of the catheter tube and the openings of the lumen may be disposed within the hub so that the opening of the first lumen is axially spaced with the end of the catheter tube. The first extension leg may be coupled to the first lumen and the second extension leg may be coupled to the second lumen for the separate delivery of fluids to the lumens.
US07901391B2
A disposable pants type wearing article includes a chassis folded in two halves along a folding guide extending in a transverse direction and these respective halves of the chassis are joined to each other along lateral edges thereof to form the article. Leg openings are defined by upper and lower leg opening edges formed by incisions in the chassis so that these upper and lower leg opening edges extending at a level a predetermined dimension above the folding guide. Above the upper leg opening edges, waist elastic members are attached and, below the lower leg opening edges, crotch elastic member are attached to the diaper. Under the contraction of these elastic members, a transverse dimension of the zone in which the waist elastic members are attached to the diaper 1 becomes larger than a transverse dimension of the zone in which the crotch elastic members are attached to the diaper.
US07901389B2
The present invention relates to an improved apparatus and method for aspirating liquids from surfaces particularly during medical procedures. Apparatus for removing liquid from a surface in the region of a medical procedure such as an operating room floor responsive to a drawn vacuum of preselected magnitude includes a plenum with an interior volume defined by an elongated box element with a plurality of supports member integral thereto or by an elongated tube, the plenum being perforated so as the exterior of the plenum is in direct liquid communication with the interior of the plenum, an absorptive wicking pad secured to the plenum so as to cover the perforations, an a vacuum conduit tube in direct vacuum communication with a vacuum collection system. A method of removal of liquids standing on surfaces such as operating room floors accomplished by positioning the disposable liquid removal apparatus with the exposed absorptive wicking pad down into the liquid, attaching the apparatus to a vacuum collection system, activating the system, and repositioning the apparatus as required.
US07901383B2
A medical regimen can be administered with a diagnostic and medication delivery system. In one form the system includes a medication delivery pen with a controller and a monitor for monitoring a characteristic of a bodily fluid with a controller. A case includes a compartment for removably storing the medication delivery pen and the monitor. The case includes a communications link for establishing communication between the controller of the pen and the controller of the monitor. The medication delivery pen and monitor are operable in a first mode cooperative with one another and in a second mode independent of one another.
US07901373B2
The present invention relates to a device for abrading or cleansing tissue. The device includes a gas inlet port connected to a pressurized gas source, and a liquid inlet port connected to a pressurized liquid source. There is, additionally, a mist jet delivery nozzle arrangement, which includes one or more gas discharge nozzles arranged to receive a flow of pressurized gas from the gas inlet port and configured to accelerate the flow of gas so as to discharge it at an elevated velocity. Further, there are one or more liquid discharge nozzles arranged to receive a flow of liquid from the liquid inlet port and operative to discharge the flow of liquid into the elevated velocity flow of gas, thereby to similarly accelerate the velocity of the discharged liquid as a mist of accelerated droplets.
US07901371B1
The present invention is a device for promoting proper posture in the user wearing the device. The device properly corrects the user's posture when he is slouching his shoulder's forward, and is discrete and comfortable to wear. Two sides of the back plate of the invention are mutually rotatable along a vertical edge which includes a pivot means comprised of a hinge or other device. The back plate further includes a spring means for biasing each side of the back plate away from the user. A pair of shoulder pads each contacts the front side of one of the user's shoulders. The spring means urges each shoulder pad rearward while urging the pivot means of the back plate forward. When the user wearing the invention slouches, the shoulder pads in the invention urge the user's shoulders backwards, thereby correcting the user's posture.
US07901367B2
The medical device includes a secondary wire guide and an advancement device. The advancement device has a tubular portion with a distal opening and a proximal opening. An edge region of the tubular portion forms the distal opening. A primary wire guide extends through the tubular portion. The secondary wire guide also extends into the tubular portion and has a distal portion configured to engage the edge region of the tubular portion. Accordingly, the secondary wire guide is advanced as the advancement device is translated into the blood vessel.
US07901366B2
Provided are a system and method for in vivo and in situ detection of body lumen conditions. The system comprises at least one interaction chamber for containing an endo-luminal sample, the interaction chamber comprising at least one indicator; at least one light source for illuminating the interaction chamber; and at least one optical detector for detecting in vivo optical changes occurring in the interaction chamber. The reaction between the indicator and sample may result in an optical change, which is detected and possibly imaged by the optical detector.
US07901359B2
A method and apparatus for improving blood flow to an ischemic region (e.g., myocardial ischemia) a patient is provided. An ultrasonic transducer is positioned proximate to the ischemic region. Ultrasonic energy is applied at a frequency at or above 1 MHz to create one or more thermal lesions in the ischemic region of the myocardium. The thermal lesions can have a gradient of sizes. The ultrasound transducer can have a curved shape so that ultrasound energy emitted by the transducer converges to a site within the myocardium, to create a thermal lesion without injuring the epicardium or endocardium.
US07901352B2
An endoscope apparatus comprises: an insertion section including a distal end; a power changing movable lens that makes observational magnification variable, the power changing movable lens being movably built in an objective optical system provided at the distal end; a linear transmission member that drives the power changing movable lens, the linear transmission member being disposed from a drive section provided at a position other than the insertion section to the distal end; a focus adjusting movable lens that achieves automatic focusing function, the focus adjusting movable lens being movably built in the objective optical system separately from the power changing movable lens; and an actuator that drives the focus adjusting movable lens, the actuator being arranged in the distal end.
US07901350B2
A cleaning adapter unit for connecting a cleaning fluid supply device to different type endoscopes comprises adapter valve assemblies which correspond to the different endoscopes, respectively. Each adapter valve assembly comprises a valve sleeve detachably connectable to the cleaning fluid supply device and a valve body received in the valve sleeve for slide movement and forming a valve chamber leading to the passage in the valve sleeve. The valve sleeve has a passage and is provided with a first fitting at one end thereof which is formed so as to be hermetically received in a valve casing of one of the different endoscopes, and the valve body is provided with first and second passages formed separately therein and opens at opposite ends, respectively, and with a second fitting at one ends thereof opposite to the one end of the valve sleeve at which the first fitting is formed so as to be hermetically received in the valve casing of the other different endoscope. The valve body brings the passage into communication with the first passage through the valve chamber when the cleaning adapter unit is attached to the one different endoscope by fitting the first fitting in the valve casing of the endoscope and with the second passage through the valve chamber when attached to the other endoscope by fitting the second fitting in the valve casing of the endoscope.
US07901348B2
Visual-assisted guidance of an ultra-thin flexible endoscope to a predetermined region of interest within a lung during a bronchoscopy procedure. The region may be an opacity-identified by non-invasive imaging methods, such as high-resolution computed tomography (HRCT) or as a malignant lung mass that was diagnosed in a previous examination. An embedded position sensor on the flexible endoscope indicates the position of the distal tip of the probe in a Cartesian coordinate system during the procedure. A visual display is continually updated, showing the present position and orientation of the marker in a 3-D graphical airway model generated from image reconstruction. The visual display also includes windows depicting a virtual fly-through perspective and real-time video images acquired at the head of the endoscope, which can be stored as data, with an audio or textual account.
US07901335B2
A multi-station exercise machine in one embodiment comprises at least two exercise stations for performing different exercises, at least one of the stations having a main frame, a user support frame pivotally associated with the main frame, a user engagement device movably mounted on one of the frames for actuating by a user in order to perform an exercise, and a connecting linkage which links movement of the user engagement device to movement of the user support. A load provides resistance to movement of the user support frame, user engagement device and/or connecting linkage. The connecting linkage, user support pivot, and user engagement device mount are arranged so that movement of the user engagement device results in self-aligning movement of the user support. The other station may have a fixed user support or a moving user support.
US07901333B1
One embodiment of an improved self-centering mechanism restoring the handlebar or control of an electronic exercise bicycle or video game bike to the straight ahead position when the rider removes his hands from the handlebars or controls. The self-centering mechanism is configured with a compression spring (52) assisting and pressurizing a mechanical device comprised of two opposing circular ball ramps (32) and (44) with radial tapered depth grooves (42). Round balls (40) of similar diameter to the radius of the depth grooves (42) are situated in the grooves (42) between the opposing ball ramps (32) and (44). The compression spring (52) is located over a connecting bolt (56) which connects the ball ramps (32) and (44) to a shaft (26) that is supported with bearings (22) and (28) in a housing (24). Below the spring assembly is the mount assembly for the potentiometer (66), which sends the data signals communicating the rotation amount of the handlebars to the video game. The anti-rotation pin (62), which is stabilized by mount for anti-rotation pin (60), prevents potentiometer (66) from rotating as a result of anti-rotation plate (64) riding against anti-rotation pin (62). Other embodiments are described.
US07901332B1
A multi-function exercise equipment is revealed. The exercise equipment includes a base and two track grooves connected by left and right links, lower links and cylinders. A pedal is mounted in each track groove and at least one locating hole is arranged at the track groove. The pedal is disposed with a locking rod that is matched to the locating hole. Moreover, at least one stop hole is set on the left link while a latch is disposed on the right link and is mounted in the stop hole. After the locking rod mounted into the locating hole and the latch mounted into the stop hole, the pedals are moved up and down synchronously. After the locking rod and the latch being released, the track grooves are parallel to a horizontal plane or inclined. The pedals slide back automatically so that users can push feet out and return.
US07901317B2
The reduction gear includes a plurality of first and second rollers that are disposed so as to directly come into rolling contact with the outer peripheries of first and second eccentric bodies; first and second retainers that maintain gaps between the first and second rollers in the circumferential direction of the first and second eccentric bodies; and first and second guide bodies of which the movement in the axial direction is restricted and which restrict the movement of the first and second rollers in the axial direction by coming into direct contact with ends of the first and second rollers.
US07901314B2
A transmission system for use in a pump system comprising a prime mover driving a pump, the transmission system comprising: an epicylic gear system comprising a sun gear and a ring gear, and a planet gear engaged between the sun gear and ring gear; a main input drive arranged to be driven by the prime mover; an auxiliary input drive arranged to be driven by the prime mover; and an output drive arranged to drive the pump; wherein the main input drive is connected to the sun gear and either (i) the auxiliary input drive is connected to the ring gear and the output drive is lead from the planet gear; or (ii) the auxiliary input drive is connected to the planet gear and the output drive is lead from the ring gear.
US07901301B2
A golf ball with at least one core layer, at least one intermediate layer, and at least one cover layer. Any combination of the layers of the golf ball may feature a visually enhancing means. The cover layer is preferably translucent and provides a view to the intermediate layer and/or the core layer. The intermediate layer has a non-uniform thickness. The core may comprise a non-spherical insert. The intermediate layer and the core layer may affect the spin rate of the golf ball. The intermediate layer may be used to indicate the alignment of the golf ball.
US07901290B2
A table game includes a lower level (2) providing a surface on which a plurality of player pieces (21) can move, an upper level (1) providing a surface on which a game is played and including a plurality of slots, a plurality of player pieces extending from the lower level and through the slots in the upper level, a plurality of electronic movement devices coupled to the player pieces to provide movement to the player pieces, and control means (4) for controlling the electronic movement of the player pieces.
US07901287B2
A gaming device having an offer and acceptance game with a plurality of award pools, a reveal feature and a modify feature. When the game is initiated, the gaming device randomly selects a pre-determined pool of awards from a plurality of pre-determined pools of awards which each includes a pre-determined initial award or offer. The awards included in the selected pool of awards are displayed to the player. The gaming device randomly associates the plurality of awards from the selected pre-determined pool of awards with a plurality of selectable selections. The gaming device enables the player to either accept the initial award or select one of the selections. If the player accepts the initial award, the player obtains the initial award and the game ends. If the player selects one of the selections, the gaming device reveals the alternate award associated with the player selected selection, the player obtains the revealed alternate award and the game ends. In one embodiment, after the player has obtained or accepted an award, the gaming device provides the player an opportunity to modify or increase the obtained award by selecting a masked choice which is associated with a modifier.
US07901280B2
A gaming system which is operable to receive an input associated with at least one betting option specified by a roulette betting layout. A plurality of roulette reels are rotatable about a common axis, and each one of the roulette reels has a side display surface or side wall. Each one of the side display surfaces or side walls displays a plurality of numerals which are spaced apart along the side display surface or side wall. The numerals are associated with the roulette betting layout. An outcome occurs based upon one or more indicated numerals.
US07901274B2
A rotary tool for surface machining has a disk having an elastomeric outer periphery, an array of angularly spaced elastomeric teeth projecting radially and each having a formation forming a hinge so that the tooth can flex at the hinge.
US07901273B2
A carrier head that has a base assembly, a retaining ring assembly, a carrier ring, and a flexible membrane is described. A carrier ring has an annular upper portion and an annular lower portion having a lower surface with a smaller inner diameter than the upper surface of the annular upper portion, wherein the carrier ring circumferentially surrounds a retaining ring and has a lower surface to contact a polishing pad.