US08754467B2
A semiconductor device includes: a semiconductor region; a plurality of stacked structures each of which is disposed on the semiconductor region and has a tunnel insulating film, a charge storage layer, an upper insulating layer, and a control electrode stacked sequentially; an element isolation insulating layer disposed on side faces of the plurality of stacked structures; and a source-drain region disposed on the semiconductor region and among the plurality of stacked structures. The element isolation insulating layer includes at least one of SiO2, SiN, and SiON, the upper insulating layer is an oxide containing at least one metal M selected from the group consisting of a rare earth metal, Y, Zr, and Hf, and Si, and respective lengths Lcharge, Ltop, and Lgate of the charge storage layer, the upper insulating layer, and the control electrode in a channel length direction satisfy the relation “Lcharge
US08754462B2
A semiconductor device includes a first electrode electrically connected to an upper surface of a semiconductor element, a first internal electrode electrically connected to a lower surface of the semiconductor element and having a plurality of first comb finger portions and a first connection portion connecting the plurality of first comb finger portions together, a second electrode electrically connected to the first internal electrode, a second internal electrode electrically connected to a lower surface of the first electrode and having a plurality of second comb finger portions and a second connection portion connecting the plurality of second comb finger portions together, the plurality of second comb finger portions being interdigitated with but not in contact with the plurality of first comb finger portions, and a lower dielectric filling the space between the plurality of first comb finger portions and the plurality of second comb finger portions.
US08754460B2
An MRAM bit (10) includes a free magnetic region (15), a fixed magnetic region (17) comprising an antiferromagnetic material, and a tunneling barrier (16) comprising a dielectric layer positioned between the free magnetic region (15) and the fixed magnetic region (17). The MRAM bit (10) avoids a pinning layer by comprising a fixed magnetic region exhibiting a well-defined high Hflop using a combination of high Hk (uniaxial anisotropy), high Hsat (saturation field), and ideal soft magnetic properties exhibiting well-defined easy and hard axes.
US08754446B2
The invention is directed to a structure and method of forming a structure having a sealed gate oxide layer. The structure includes a gate oxide layer formed on a substrate and a gate formed on the gate oxide layer. The structure further includes a material abutting walls of the gate and formed within an undercut underneath the gate to protect regions of the gate oxide layer exposed by the undercut. Source and drain regions are isolated from the gate by the material.
US08754445B2
A layer in which the potential level difference normally unrequired for device operation is generated is positively inserted in a device structure. The potential level difference has such a function that even if a semiconductor having a small bandgap is exposed on a mesa side surface, a potential drop amount of the portion is suppressed, and a leakage current inconvenient for device operation can be reduced. This effect can be commonly obtained for a heterostructure bipolar transistor, a photodiode, an electroabsorption modulator, and so on. In the photodiode, since the leakage current is alleviated, the device size can be reduced, so that in addition to improvement of operating speed with a reduction in series resistance, it is advantageous that the device can be densely disposed in an array.
US08754441B2
The semiconductor light-emitting device (11) of the present invention includes a substrate (1); a laminate semiconductor layer (15) comprised of an n-type semiconductor layer (3) formed on the substrate (1), a light-emitting layer (4) laminated on the n-type semiconductor layer (3) and a p-type semiconductor layer (5) laminated on the light-emitting layer (4); a concavo-convex part (33) for improving a light extraction efficiency, which is formed on all or a part of a top surface (15a) of the laminate semiconductor layer (15); a high-concentration p-type semiconductor layer (8) having a higher dopant concentration than that of the p-type semiconductor layer (5), which is laminated on a convex part (33a) that constitutes the concavo-convex part (33) of the laminate semiconductor layer (15); and a translucent current diffusion layer (20) laminated on at least the high-concentration p-type semiconductor layer (8).
US08754433B2
According to one embodiment, a semiconductor device includes a switch element provided in a surface area of a semiconductor substrate, a contact plug with an upper surface and a lower surface, and a function element provided on the upper surface of the contact plug. The lower surface of the contact plug is connected to the switch element. The upper surface of the contact plug has a maximum roughness of 0.2 nm or less.
US08754431B2
According to one embodiment, a semiconductor light emitting device includes first and second electrode layers, a and second semiconductor layers, a light emitting layer and a first intermediate layer. The first electrode layer has a metal portion having through-holes. The second electrode layer is stacked with the first electrode layer along a stacked direction, and light-reflective. The first semiconductor layer is provided between the first and second electrode layers, and has a first conductivity type. The second semiconductor layer is provided between the first semiconductor layer and the second electrode layer, and has a second conductivity type. The light emitting layer is provided between the first and second semiconductor layers. The first intermediate layer is provided between the second semiconductor layer and the second electrode layer, transmissive to light emitted from the light emitting layer, and includes first contact portions and a first non-contact portion.
US08754421B2
Forming an alignment mark on a semiconductor structure using an optical lithography to form a metal alignment mark on a substrate of the structure, using the formed metal alignment mark to form a first feature of a semiconductor device being formed on the substrate using optical lithography, and using the formed metal alignment mark to form a second, different feature for the semiconductor using electron beam lithography. In one embodiment, the first feature is an ohmic contact, the second feature is a Schottky contact, the metal alignment mark is a refractory metal or a refractory metal compound having an atomic weight greater than 60 such as TaN and the semiconductor device is a GaN semiconductor device. A semiconductor structure having a metal alignment mark on a zero layer of the structure, the metal alignment mark is a TaN and the semiconductor is GaN.
US08754415B2
The present disclosure relates to a high light transmittance in-plan switching liquid crystal display device and a method for manufacturing the same. The liquid crystal display device includes: a substrate; a gate line disposed in horizontal direction on the substrate; a gate insulating layer covering the gate line; a data line disposed in vertical direction on the gate insulating layer; an additional insulating layer on the data line having same size and shape with the data line; a passivation layer covering the additional insulating layer; and a common electrode overlapping with the data line on the passivation layer. According to the present disclosure, the failure due to the parasitic capacitance and the load for driving the display panel are reduced and it is possible to make large and high definition display panel.
US08754410B2
An array substrate includes a gate line on a substrate including a pixel region, the gate line extending in one direction; a gate electrode in the pixel region and extending from the gate line; a gate insulating layer on the gate line and the gate electrode; a data line on the gate insulating layer and crossing the gate line to define the pixel region; an oxide semiconductor layer on the gate insulating layer and having three ends, the oxide semiconductor layer corresponding to the gate electrode; an etch stopper on the oxide semiconductor layer to expose the three ends of the oxide semiconductor layer; a source electrode contacting two ends of the three ends of the oxide semiconductor layer and extending from the data line; and a drain electrode contacting one end of the three ends of the oxide semiconductor layer and spaced apart from the source electrode.
US08754407B2
Disclosed is a gas barrier film which has both high gas barrier performance and high cracking (bending) resistance. Specifically disclosed is a gas barrier film which comprises, on a substrate in the following order, at least one silanol-containing layer and at least one gas barrier layer that contains silicon atoms and hydrogen atoms. The gas barrier film is characterized in that the relative SiOH ion strength in the central part of the silanol-containing layer in the film thickness direction as detected by time-of-flight secondary ion mass spectrometry (Tof-SIMS) is 0.02-1.0 when the relative Si ion strength is taken as 1. Also disclosed is an organic photoelectric conversion element which comprises the gas barrier film.
US08754405B2
An organic electroluminescence device includes a cathode, a stacked structure provided on the cathode and including an organic layer that includes an organic light emitting layer, and a transparent anode provided on the stacked structure, The transparent anode includes a metal oxide and a conductive polymer.
US08754397B2
The carbon nanotube-based electronic and photonic devices are disclosed. The devices are united by the same technology as well as similar elements for their fabrication. The devices consist of the vertically grown semiconductor nanotube having two Schottky barriers at the nanotube ends and one Schottky barrier at the middle of the nanotube. Depending on the Schottky barrier heights and bias arrangements, the disclosed devices can operate either as transistors, CNT MESFET and CNT Hot Electron Transistor, or as a CNT Photon Emitter.
US08754394B2
A variable resistive memory device includes a bit line, a word line, first electrodes and second electrodes, which are respectively arrayed in different directions, wherein a unit cell including a variable resistive material layer interposed between the first electrode and the second electrode is located at every intersection between the first electrode and the second electrode.
US08754390B2
A method is provided for generating measurement parameters for a particle sample in a particle analyzer. The method includes, interrogating the particle sample with a triggering interrogator and one or more secondary interrogators respectively positioned along a length of an interrogation area, generating respective pulses based upon the interrogation of a first particle from the particle sample, determining a primary pulse detection window based upon a triggering pulse, determining a search interval to find a secondary pulse based upon factors including the primary pulse detection window and a laser delay, adjusting the search interval for laser delay variation dynamically based on the interrogation of the first particle, identifying the secondary pulse in the adjusted search interval, and processing the secondary pulse to determine a peak value of the secondary pulse. Corresponding apparatus are also provided.
US08754387B2
A radioactive material handling assembly (10) includes an outer housing (12) and an inner cell (14). The inner cell defines a radioactive material containment/handling chamber (16) and is removably mountable inside the outer housing. Handling means is operable from outside the inner cell to handle radioactive materials located in the containment/handling chamber. At least one of the outer housing and the inner cell is predominantly of a shielding material which is opaque to radioactivity.
US08754386B2
There are provided a leaf row (5C) in which a plurality of leaf plates (5L) are arranged in the thickness direction of the row (5C) in such a way that respective end faces (EL) of the leaf plates (5L) are trued up, and a leaf plate drive mechanism (5D) that drives each of the plurality of leaf plates (5L) in such a way that the end face (EL) approaches or departs from a beam axis (XB). In each of the leaf plates (5L), a facing side (PL) facing a leaf plate that is adjacent to that leaf plate in the thickness direction is formed of a plane (Psa) including a first axis (Asa) on the beam axis (XB); the leaf plate drive mechanism (5D) drives the leaf plate (5L) along a circumferential orbit (OL) around the second axis (Asb), on the beam axis (XB), that is perpendicular to the beam axis (XB) and the first axis (Asa).
US08754384B1
Described is a system and method for in situ sample preparation and imaging. The system includes a multi-axis stage 100 having a bulk stage 110 and a grid stage 150 with various degrees of freedom to allow for sample preparation. In some embodiments, a focused ion beam system is used to prepare a lamella on the bulk stage 110. The lamella can then be transferred to the grid stage 150 from the bulk stage 110 without needing to move the multi-axis stage 100 from the focused ion beam system.
US08754381B2
The present invention provides a method for inspecting UV illuminance in multi-level UV bake furnace for TFT-LCD manufacturing process and a pickup assembly device for performing the method. The method for inspecting UV illuminance in multi-level UV bake furnace for TFT-LCD manufacturing process includes the following steps: Step 1: providing a multi-level bake furnace for TFT-LCD manufacturing process, a pickup device, an inspection control system, and a sensor for inspecting UV illuminance; Step 2: mounting the sensor on the pickup device; Step 3: connecting the inspection control system and the sensor with communication; Step 4: operating the pickup device to bring the sensor to a site in a level of the multi-level UV bake furnace where inspection of UV illuminance is to be made; and Step 5: sensor collecting data and transmitting the data so collected to the inspection control system to thereby realize inspection. The pickup assembly device includes a pickup device and a sensor mounted to the pickup device.
US08754373B2
A pyroelectric element includes a pyroelectric substrate; a light-receiving section composed of a front-side electrode, a back-side electrode, and a light-receiving portion; and a light-receiving section composed of a front-side electrode, a back-side electrode, and a light-receiving portion. Since the pyroelectric substrate warps in a cavity-facing region opposite a cavity, the light-receiving area of the light-receiving sections is greater than that in the case where there is no warp. It is thus possible to improve detection sensitivity of the pyroelectric element without making the size of the pyroelectric element larger than that in the case where there is no warp.
US08754370B1
A sheathless interface for coupling capillary electrophoresis (CE) with mass spectrometry is disclosed. The sheathless interface includes a separation capillary for performing CE separation and an emitter capillary for electrospray ionization. A portion of the emitter capillary is porous or, alternatively, is coated to form an electrically conductive surface. A section of the emitter capillary is disposed within the separation capillary, forming a joint. A metal tube, containing a conductive liquid, encloses the joint.
US08754369B2
A measuring method including the steps of providing a chamber, drawing a vacuum in the chamber, placing a sample into the chamber, heating the sample to desorb a target species from the sample, passing a carrier gas through the chamber, the carrier gas mixing with the desorbed target species to form a mixture, and analyzing the mixture.
US08754357B2
A pixel includes a photo-sensitive element for generating charges in response to incident radiation. A transfer gate is positioned between the photo-sensitive element and a sense node for controlling transfer of charges to the sense node. A reset switch is connected to the sense node for resetting the sense node to a predetermined voltage. A first buffer amplifier has an input connected to the sense node and an output connected to a sample stage operable to sample a value of the sense node. A second buffer amplifier has an input connected to the sample stage. Control circuitry operates the reset switch and causes the sample stage to sample the sense node while the photo-sensitive element is exposed to radiation. An array of pixels is synchronously exposed to radiation. Sampled values for a first exposure period can be read while the photo-sensitive element is exposed for a second exposure period.
US08754353B2
Disclosed herein is a solar cell system including: a plurality of power generation panels that differ in the range of wavelengths of light they absorb from each other and convert light into power; a voltage detection section adapted to detect the voltage of power generated by each of the plurality of power generation panels; a reproduction section adapted to compare the voltages of the plurality of power generation panels detected by the voltage detection section so as to reproduce an audio or music signal appropriate to the comparison result; and an output section adapted to output audio or music reproduced by the reproduction section.
US08754351B2
An induction cooking system with an induction heating system, a cooktop, and cool touch cookware that has a target layer that is heated by induction. An absolute cookware temperature is directly sensed at one or more locations of the cookware. A relative cookware temperature can be determined based on the value of an electrical variable of a circuit that includes the target layer. The cookware can include a layer of thermal insulation directly below and spaced from the target layer by a gap. The insulation and gap act as the major heat insulating elements to keep the outer surface of the cookware cool. The cooktop can be cooled by placing a cooling chamber just below the cooktop and drawing air through the cooling chamber. The induction coil can be located in the cooling chamber.
US08754349B2
A method of operating a plasma arc torch system includes placing a work piece to be cut on a table of the plasma arc torch system, wherein at least a portion of the work piece has a planer surface facing away from the table. A plasma arc torch is positioned adjacent the planer surface of the work piece using a positioning apparatus, wherein the positioning apparatus has at least five degrees of freedom about which it can move the plasma arc torch relative the work piece for cutting the work piece on the table. The method further includes angling the torch relative the planer surface of the work piece such that the torch is held at an angle of between about 1 and about 4 degrees from perpendicular with the planer surface to back burn a produced kerf such that a kerf edge is perpendicular relative the planer surface of the work piece. Additionally, the planer surface of the work piece is calculated by contacting the work piece with the torch at least three times.
US08754347B2
A resistance spot welder includes: a motor, having a shaft; a cylindrical casing; a hollow guide rod, inserted into the casing, and adapted to be moved linearly for moving a first electrode tip facing a second electrode tip provided at a gun arm; a ball nut, fixed in an inner circumference of the guide rod; a ball screw, fitted through the ball nut; a coupling, including a first fastening portion into which the shaft of the motor is inserted and a second fastening portion into which the ball screw is inserted and which is opposite to the first fastening portion; and a bearing, fitted between an outer circumference of the first fastening portion and an inner circumference of the casing. The guide rod is moved between a first point which is a motor side and a second point which is an electrode tip side. When the guide rod is positioned at the first point, the guide rod accommodates at least a part of the second fastening portion.
US08754340B2
Methods, apparatus and systems which provide buttons oriented at angles relative to each other as a part of a multiple function switch are described. In one embodiment, the multiple function switch is part of an inline controller that is suitable for use to control features or functions of a portable electronic device. A multiple function switch may be incorporated in a cable associated with an earpiece arranged to be interfaced with a portable electronic device.
US08754336B2
A wiring board includes: wiring layers; insulating layers disposed between the wiring layers; and external connection pads respectively including surface plated layers, for connecting to an external circuit. In each of the external connection pads in one face of the wiring board, an outer peripheral edge of the external connection pad is retracted from an outer peripheral edge of the surface plated layer toward a center of the external connection pad.
US08754332B2
Provided is a flexible substrate wherein a connection portion between the flexible substrate and an electric circuit board meets requirements of narrow wiring pitch and low resistance at the connection portion. An electric circuit structure, which has the flexible substrate and the electric circuit board to which the flexible substrate is connected, is also provided. A wiring pattern (22) is formed on a flexible base film (21), a connection terminal (25) connected electrically to an electrode terminal of another electric circuit board is arranged at an end portion of the wiring pattern (22), and the connection terminal (25) includes wide connection terminals (25b, 25c) having a terminal width extending across plural lines of the wiring pattern (22).
US08754331B2
Disclosed is an exemplary strain relief device. The strain relief device includes a tubular body having a central bore, a plurality of cable passages disposed around the central bore, and a plug to block the central bore and secure the one or more telecommunication drop cables in the cable passages. the central bore defines a longitudinal axis and an interior surface of the tubular body. The central bore has a perimeter that is larger than a perimeter of each of the plurality of cable passages.
US08754323B2
A dye-sensitized solar cell is provided, wherein it can be produced by a relatively easy and simple process and ensures high conversion efficiency even in cases where the thickness of the porous semiconductor layer is increased. The dye-sensitized solar cell 10 includes, in the interior of or on the conductive-substrate-side surface of the porous semiconductor layer 16, conductive metal film 20, such as a film of tungsten, having a large number of randomly located penetrations 24. Penetrations 24 of the conductive metal film 20 are formed by forming a fine-particle layer on the surface of the porous semiconductor layer, forming a conductive metal film on the surface of the fine-particle layer, and making the fine-particle layer disappear by heating or solvent-cleaning.
US08754321B2
A thermoelectric segment and a method for fabricating. The fabricating includes forming structures by depositing thin-film metal-semiconductor multilayers on substrates and depositing metal layers on the multilayers, joining metal bonding layers to form dual structures with combined bonding layers; and removing at least one of the substrates; and using the dual structure to form a thermoelectric segments. The method can include dicing the dual structures before or after removing the substrates. The method can include depositing additional bonding layers and joining dual structures to make thermoelectric segments of different thicknesses. Each multilayer can be about 5-10 μm thick. Each bonding layer can be about 1-2 μm thick. The bonding layers can be made of a material having high thermal and electrical conductivity. The multilayers can be (Hf,Zr,Ti,W)N/(Sc,Y,La,Ga,In,Al)N superlattice layers. Metal nitride layers can be deposited between each of the bonding layers and multilayers.
US08754320B2
A composite material with tailored anisotropic electrical and thermal conductivities is described. A material consists of a matrix material containing inclusions with anisotropic geometrical shapes. The inclusions are arranged in layers oriented perpendicular to the principal direction of electrical and thermal energy flow in the material. The shapes of the inclusions are such that they represent strong or weak barriers to energy flow depending on whether the major axis of the inclusions are parallel to or antiparallel to the flow direction.
US08754312B2
A neck for a string instrument is provided with a shape that varies along the length of the neck to facilitate an appropriate hand posture at various longitudinal positions on the neck. The neck has a heel end for receiving a body of a string instrument, a head end relative to the heel end, and a fingerboard surface. Adjacent the fingerboard surface, the bass side of the neck is chamfered, relative to the treble side of the neck, from an intermediate position between the heel end and the head end of the neck toward the heel end of the neck, for accommodating a user's thumb when fretting in an upper register portion of the neck.
US08754295B2
The invention relates to the soybean variety designated A1035590. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1035590. Also provided by the invention are tissue cultures of the soybean variety A1035590 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1035590 with itself or another soybean variety and plants produced by such methods.
US08754294B1
A novel soybean variety, designated XBP52003 is provided. Also provided are the seeds of soybean variety XBP52003, cells from soybean variety XBP52003, plants of soybean XBP52003, and plant parts of soybean variety XBP52003. Methods provided include producing a soybean plant by crossing soybean variety XBP52003 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XBP52003, methods for producing other soybean varieties or plant parts derived from soybean variety XBP52003, and methods of characterizing soybean variety XBP52003. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XBP52003 are further provided.
US08754284B2
The present invention relates to a method of deactivating an explosive composition in order to render the composition safe. The present invention also relates to a cartridge that contains an explosive composition and that is adapted to achieve deactivation of the explosive composition in the event that it is not detonated as intended during use.
US08754280B2
The present invention provides a method for start-up of an Oxygenate-to-Olefins process, which process comprises the steps: a) providing an oxygenate-comprising feedstock to an Oxygenate-to-Olefins reaction zone and contacting the feedstock with a zeolite-comprising catalyst at a temperature in the range of from 450 to 700° C. ° C., to obtain an reaction product containing olefins; b) separating the reaction product obtained in step a) in at least a product fraction containing ethylene and/or propylene and a product fraction containing C4+ olefins; c) recycling at least part of the C4+ olefins in the product fraction containing C4+ olefins to the Oxygenate-to-Olefins reaction zone in step (a), characterized in that upon start-up the oxygenate-comprising feedstock initially comprises a first amount of externally supplied tert-alkyl ether and subsequently the amount of externally supplied tert-alkyl ether in the oxygenate-comprising feedstock is reduced.
US08754278B2
A aromatic alkylation catalyst, processes for producing the catalyst, and aromatic alkylation processes employing the catalysts are disclosed. The catalyst comprises a UZM-8 zeolite and nitrogen, and the catalyst has a nitrogen to zeolite aluminum molar ratio of at least about 0.015. In an exemplary alkylation process, the catalyst provides improved product yield.
US08754277B2
The present invention provides a process for preparing ethylene and/or propylene, comprising the steps of providing a hydrocarbon stream, comprising C4+ normal olefins and C4+ iso-olefins; converting C4+ isoolefins to tert-alkyl ether and separating the ethers from the hydrocarbon stream; isomersing the C4+ normal olefins to iso-olefins and converting C4+ isoolefins to tert-alkyl ether and separating the ethers from the hydrocarbon stream; converting the obtained tert-alkyl ether to ethylene and propylene by contacting the tert-alkyl ether with a molecular sieve-comprising catalyst and retrieving an olefinic product.
US08754261B2
The present invention relates to a novel process for the preparation of O-desmethyl venlafaxine (ODV) and the pharmaceutically acceptable salts thereof, wherein it comprises (i) provision of spiro-venlafaxine compound as intermediate; (ii) conversion of spiro-venlafaxine intermediate into ODV free base in a one-pot process; and (iii) optionally conversion ODV free base into pharmaceutically acceptable salts. The present invention further relates to novel processes for the preparation of crystalline salts of ODV-succinate and ODV-oxalate.
US08754258B2
The present invention discloses a novel form of ferric organic compounds, including a form of ferric citrate, which are soluble over a wider range of pH, and which have a large active surface area. The ferric organic compounds of the present invention can be delivered effectively by oral route with better delivery to treat patients suffering from hyperphosphatemia, metabolic acidosis and other disorders responsive to ferric organic compound therapy.
US08754254B2
A process for purifying crude terephthalic acid comprising a contaminant at a first concentration, the process comprising contacting the crude terephthalic acid with a solvent comprising an ionic liquid at purifying conditions to produce a solid terephthalic acid product having a second concentration of the contaminant lower than the first concentration.
US08754253B2
An process to obtain a mixture of lower carboxylic acid mono, di and triesters, from raw glycerin, a by-product of the process to obtain biodiesel, a transesterification of vegetable raw material with lower alcohols is described. Also described is a process to obtain triacetin or a mixture of mono-, di- and triacetin from that raw glycerin, without prior purification.
US08754246B2
Embodiments of the present disclosure include a process for separating phases of a mixture including a liquid aqueous phase, a liquid organic phase, and a solid phase and extracting at least an oxirane from the liquid aqueous phase with an extraction solvent.
US08754240B2
The present invention relates to a chemical process for the manufacture of a compound of Formula II
US08754237B2
In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel bifunctional, trifunctional, or multifunctional compounds for inhibiting histone deacetylases, and pharmaceutically acceptable salts and derivatives thereof. The present invention further provides methods for treating disorders regulated by histone deacetylase activity (e.g., proliferative diseases, cancer, inflammatory diseases, protozoal infections, hair loss, etc.) comprising administering a therapeutically effective amount of an inventive compound to a subject in need thereof. The present invention also provides methods for preparing compounds of the invention.
US08754234B2
The present invention provides chiral 2-(benzylsulfinyl)thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives of the formula (I) and their salts processes for their preparation and their use as herbicides and plant growth regulators, in particular as herbicides for the selective control of harmful plants in crops of useful plants.
US08754220B2
The present invention is directed to compounds of formula (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor.
US08754217B2
The present invention relates to the Nalmefene hydrochloride dihydrate, methods of manufacturing Nalmefene hydrochloride dihydrate, a pharmaceutical composition comprising Nalmefene hydrochloride dihydrate and a method of treatment comprising administering Nalmefene hydrochloride dihydrate.
US08754215B2
The present disclosure describes a novel, cost-effective process for preparation of a 4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino-[2,1-a]isoquinoline derivatives. Specifically, it discloses a process for the preparation of the anthelmintic drug praziquantel through the use of a novel intermediate, 2-[(2,2-dimethoxyethyl)benzyl amino]-N-phenethylacetamide. This present disclosure also describes a novel crystalline form of 4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline.
US08754199B2
The invention provides isolated nucleic acid molecules, designated TANGO 228 nucleic acid molecules, which encode secreted proteins with homology to the rat MCA-32 protein, isolated nucleic acid molecules, designated TANGO 240 nucleic acid molecules, which encode secreted proteins with homology to the Mycobacterium tuberculosis hypothetical protein Rv0712, and isolated nucleic acid molecules, designated TANGO 243 nucleic acid molecules, which encode proteins with homology to human PLAP (phospholipase A2-activating protein).The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
US08754193B2
A family of GFP scaffolds capable of accommodating two proximal, randomized binding loops is disclosed. GFP-based binders binding with nanomolar affinity are developed from a library of these GFP scaffolds.
US08754184B2
A prepolymer mixture for preparing a polyurethane elastomer, the mixture comprising an isocyanate terminated prepolymer and a nitrogen-containing organic salt. The nitrogen-containing organic salt may be selected from the group consisting of an ammonium salt, an imidazolium salt, a pyridinium salt, a pyrrolidinium salt, a piperidinium salt, and a morpholinium salt.
US08754178B2
A resin composition of the present invention includes a maleimide derivative (A) represented by a general formula (1) and a bis-maleimide compound (B) represented by a general formula (2). In the general formula (1), R1 represents a straight chain or branched alkylene group having 1 or more carbon atoms, R2 represents a straight chain or branched alkyl group having 5 or more carbon atoms, and the sum of carbon atoms of R1 and R2 is 10 or less. In the general formula (2), X1 represents —O—, —COO—, or —OCOO—, R3 represents a straight chain or branched alkylene group having 1 to 5 carbon atoms, R4 represents a straight chain or branched alkylene group having 3 to 6 carbon atoms, and m is an integer of 1 or more and 50 or less.
US08754177B2
The invention relates to a polymerization process, the polymerization process includes contacting a cyclic bridged metallocene catalyst represented by the following formula: LA(A)LBMQn wherein A is a divalent group bound to each of LA and LB; each of LA and LB are bound to M, and each Q is bound to M; LA and LB are independently selected from the group consisting of cyclopentadienyl ligands and substituted cyclopentadienyl ligands; A is a divalent bridging group comprising a heterocyclic ring comprising from 3 to 6 carbon atoms and one silyl, thus forming a 4 to 7 member divalent ring; M is a Group 4, 5, or 6 transition metal; Q is independently a halogen, a hydride, or a hydrocarbyl radical having from 1 to 20 carbon atoms; wherein n is 1 or 2; with an activator, and optionally a support, to form an activated catalyst and, subsequently, contacting the activated catalyst with ethylene and optionally, at least one C3-C8 alpha olefin comonomer.
US08754173B2
The present invention relates to a process for the continuous production of polymer mixtures comprising: a) from 10 to 80% by weight of a biodegradable polyester (Q) composed of aliphatic or aliphatic and aromatic dicarboxylic acids and of aliphatic dihydroxy compounds, and b) from 20 to 90% by weight of one or more polymers (T) selected from the group consisting of: polylactic acid, polycaprolactone, polypropylene carbonate, polyglycolide, aliphatic polyester, cellulose acetate, and polyhydroxyalkanoate, where i) a mixture composed of the aliphatic dihydroxy compounds, of the aliphatic and aromatic dicarboxylic acids and, if appropriate, of further comonomers (component C) is mixed, without addition of any catalyst, to give a paste or, as an alternative, the liquid esters of the dicarboxylic acids are fed into the system, as also are the dihydroxy compound and, if appropriate, further comonomers, without addition of any catalyst, and in a first stage this mixture, together with the entire amount or with a portion of the catalyst, is continuously esterified or transesterified; ii) in a second stage, the transesterification or, respectively, esterification product obtained in i) is continuously precondensed to an intrinsic viscosity of from 20 to 70 cm3/g to DIN 53728; iii) in a third stage, the product obtainable from ii) is continuously polycondensed as far as an intrinsic viscosity of from 60 to 170 cm3/g to DIN 53728, and iv) in a fourth stage, the product obtainable from iii) (polyester Q) is continuously mixed with the polymer T, and v) if appropriate, in a fifth stage, the polymer mixture obtainable from iv) is continuously reacted in a polyaddition reaction with a chain extender D as far as an intrinsic viscosity of from 150 to 320 cm3/g to DIN 53728.
US08754166B2
A multilayer paint system wherein each layer of paint uses the same activator and the same mixing ratio of film-forming binder to activator. The paint system herein is particularly useful for automotive refinishing applications.
US08754164B2
A rubber composition for the manufacture of tires, based on one or more diene elastomers, on one or more reinforcing fillers and on a vulcanization system, characterized in that the said vulcanization system comprises one or more 1,2,4-triazine compounds of formula:
US08754158B2
The present invention has its object to provide a high performance studless tire for a passenger vehicle which has both good braking force and high handling stability on ice or snow. The studless tire for a passenger vehicle comprises a tread having a total sulfur content of 0.7% by mass or less and having a crosslink density of 2.0×10−5 mol/cm3 or higher.
US08754156B2
A new method for producing a thioester group-containing organosilicon compound by a convenient reaction with dramatically improved workability generating reduced byproduct is provided. The method comprises reacting an organosilicon compound having a hydrolyzable silyl group and mercapto group with a carboxylic anhydride. Also provided are an organosilicon compound having a hydrolyzable silyl group, a thioester group, and carboxyl group in the same molecule capable of remarkably reducing hysteresis loss of the cured rubber composition; a compounding agent for rubber containing such organosilicon compound; a rubber composition prepared by blending such compounding agent for rubber; and a tire produced by using the cured rubber composition are also provided.
US08754154B2
The present invention relates to phosphorus-containing triazine compounds of the formula (I) and (III) and to the polymers obtainable from the water-eliminating polycondensation of a compound of the formula (II), and to the use thereof as flame retardants. [(A-H)+]m[Mm+(HPO42−)m] (III-1), [(A-H)+]m[Mm+(P2O74−)m/2] (III-2).
US08754152B2
A reinforced polymer composite, and more particularly, a wool reinforced polymer composite is provided. The composition includes wool fibers combined with a polymer to form a reinforced polymeric matrix having at least one of improved Izod Impact Strength (ASTM D-256) or improved Tensile Strength (ASTM D-1708) as compared to the polymer without the fibers.
US08754134B2
Disclosed are compositions that include treated biodiesel glycerin. The disclosed compositions may be utilized as soil-amendments for controlling pests, weeds and for enhancing growth of plants. The biodiesel glycerin utilized in the disclosed compositions may be treated by one or more steps including neutralization, heating, refluxing, condensing, and distilling.
US08754130B2
A biocidal composition comprising 2,2-dibromomalonamide and an isothiazolinone-based biocide, and its use for the control of microorganisms in aqueous and water-containing systems.
US08754127B2
Disclosed herein are compounds that may be specific to PPAR and/or EGF receptors, and methods of making and using same.
US08754118B2
[Object] A prophylactic or therapeutic agent for a cardiovascular disease is provided.[Means for Resolution] An atropisomer of a compound represented by the following general formula (I): (wherein R1 is a C1-C3 alkyl group or a hydroxy-C1-C3 alkyl group; and R2 is a hydrogen atom or a C1-C3 alkoxy group).
US08754108B2
Lyophilized pantoprazole preparations which are obtainable by freeze-drying of an aqueous solution of pantoprazole, ethylenediamine tetraacetic acid and/or a suitable salt thereof, and sodium hydroxide and/or sodium carbonate are disclosed. The preparations have advantageous properties when reconstituted for injection.
US08754099B2
Beta-carboline derivatives of structural formula I are selective antagonists of the somatostatin subtype receptor 3 (SSTR3) and are useful for the treatment of Type 2 diabetes mellitus and of conditions that are often associated with this disease, including hyperglycemia, insulin resistance, obesity, lipid disorders, and hypertension. The compounds are also useful for the treatment of depression and anxiety.
US08754093B2
Etravirine (TMC125) nicotinamide co-crystal, its preparation, and use in the treatment of HIV infection.
US08754088B2
The present invention provides compositions comprising sucralose and 4-amino-5,6-dimethylthieno[2,3-d]pyrimidine-2(1H)-one or salts, solvates, and/or esters thereof and methods of making the compositions by spray drying. The present invention also provides ingestible compositions comprising compositions of the present invention and methods of making such foods. The present invention also includes a process of preparing 2-amino-thiophene derivatives, which are key intermediates for preparing 4-amino-5,6-dimethylthieno[2,3-d]pyrimidine-2(1H)-one.
US08754087B2
The present invention relates to a method for the treatment or prevention of atrial fibrillation and/or atrial flutter comprising coadministration of a synergistically therapeutic amount of dronedarone or a pharmaceutically acceptable salt or salts thereof and a synergistically therapeutic amount of ranolazine or a pharmaceutically acceptable salt or salts thereof. Also provided are methods for modulating ventricular and atrial rhythm and rate. This invention also relates to pharmaceutical formulations that are suitable for such combined administration.
US08754072B2
The present invention relates to novel polymorphic forms of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one, and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a mammalian disease condition mediated by poly(ADP-ribose) polymerase activity including the disease condition such as cancer.
US08754069B2
Compounds of Formula I: that possess unique antiviral activity are provided as HIV maturation inhibitors. These compounds are useful for the treatment of HIV and AIDS.
US08754067B2
This invention discloses 22-haloacetoxy-homopregnacalciferol analogs and specifically 22-bromoacetoxy-homopregnacalciferol and pharmaceutical uses therefor. This compound exhibits relatively little calcemic activity and does not promote cellular differentiation off HL-60 leukemia cells, but rather kills the cells. This cell death activity is found in small cell lung carcinoma also, but not in prostate cancer cells. This compound thus causes specific cell death in the absence of changes in calcium levels and without general toxicity in an animal. Therefore it might serve as a useful therapy for treatment of some forms of cancer, such as leukemia and lung cancer.
US08754065B2
A hemifumarate form of 9-[(R)-2-[[(S)-[[(S)-1-(isopropoxycarbonyl)ethyl]amino]phenoxyphosphinyl]methoxy]propyl]adenine (tenofovir alafenamide), and antiviral therapy using tenofovir alafenamide hemifumarate (e.g., anti-HIV and anti-HBV therapies).
US08754062B2
The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity.
US08754048B2
Disclosed is a Volvox carteri-derived light-receiving channel rhodopsin with an improved expression efficiency on a cell membrane. Specifically disclosed is a modified Volvox carteri-derived light-receiving channel rhodopsin protein. The protein is modified to contain an N-terminal region of Chlamydomonas reinhardtii-derived channel rhodopsin-1 at the N-terminal of the Volvox carteri-derived light-receiving channel rhodopsin protein, wherein the N-terminal region is involved in cell membrane-localized expression and contains no transmembrane domain of the Chlamydomonas reinhardtii-derived channel rhodopsin-1.
US08754046B2
The present invention discloses the identification and isolation of novel MHC class II epitopes derived from the cancer antigen, NY ESO-1. The novel MHC class II epitopes from NY-EsO-1 are recognized by CD4+ T lymphocytes in an HLA class II restricted manner, in particular HLA-DR or HLA-DP restricted. The products of the gene are promising candidates for immunotherapeutic strategies for the prevention, treatment and diagnosis of patients with cancer.
US08754036B2
An object of the present invention is to provide a substance which is able to be an active ingredient for the improvement of dysfunction caused by nerve damage. An improving agent for dysfunction due to nerve damage of the present invention as a means for resolution thereof is characterized in that it comprises an endo-β-N-acetylglucosaminidase type enzyme which hydrolyzes an N-acetylglucosamide bond in a keratan sulfate backbone as an active ingredient. When the improving agent of the present invention is administered, clinical improvement is achieved in motor neuron dysfunction and sensory neuron dysfunction such as neuropathic pain represented by a pain caused by allodynia and hyperalgesic reaction of the object to be treated.
US08754033B2
Disclosed herein are transglutaminase peptide inhibitors which have inhibitory activity against transglutaminase, and a pharmaceutical composition comprising one of them as an active ingredient. The inhibitors or the composition is useful in the prevention and treatment of various diseases caused by aberrant transglutaminase activation, including inflammatory diseases and cancers. Also, methods for treating various inflammatory diseases and cancers and for preparing mutant peptides capable of inhibiting transglutaminase are also disclosed.
US08754021B2
A cleaning composition and process for cleaning post-chemical mechanical polishing (CMP) residue and contaminants from a microelectronic device having said residue and contaminants thereon. The cleaning compositions are substantially devoid of amine and ammonium-containing compounds, e.g., quaternary ammonium bases. The composition achieves highly efficacious cleaning of the post-CMP residue and contaminant material from the surface of the microelectronic device without compromising the low-k dielectric material or the copper interconnect material.
US08754016B2
The lubricating base oil of the invention is characterized by having an urea adduct value of not greater than 4% by mass and a viscosity index of 100 or greater. The process for production of a lubricating base oil according to the invention is characterized by comprising a step of hydrocracking/hydroisomerization of a stock oil containing normal paraffins, until the obtained treatment product has an urea adduct value of not greater than 4% by mass and a viscosity index of 100 or greater. A lubricating oil composition according to the invention is characterized by comprising the lubricating base oil of the invention.
US08754012B2
The present invention relates to methods of screening for expression of a soluble candidate protein within an expression library of candidate proteins. The method involves fusing each candidate protein in the library to a peptide substrate and identifying cells that express soluble candidate protein by detecting enzymatic modification of the peptide substrate.
US08754008B2
The present invention relates to benzoxazinones of the general formula (I) wherein the variables are defined according to the description, processes and intermediates for preparing the benzoxazinones of the formula (I), compositions comprising them and their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidal effective amount of at least one benzoxazinones of the formula (I) to act on plants, their seed and/or their habitat.
US08754005B2
The present disclosure relates to a color-changing composition and to a substrate having the color-changing compositions disposed thereon. The color-changing composition includes a leuco dye, a color-developer and a desensitizer. The color-changing composition changes from a colorless or largely colorless composition to color upon being wetted with an aqueous liquid. The color-changing composition remains colorless or largely colorless prior to exposure to high relative humidity conditions.
US08753999B2
A catalyst for selective oxidation of hydrocarbons relative to carbon monoxide includes a mixed oxide based on the compound Ce0.1-0.5Ti0.2-0.8Cr0.1-0.5Ox, wherein x is (the total of the valences of the metals)/2. Preferably, the mixed oxide is fixed as a coating on a molded body or less than 0.5 wt. % precious metal is doped to the mixed oxide. Oxidizable exhaust-gas components are oxidized for exhaust-gas purification by a mixed oxide based on the compound Ce0.1-0.5Ti0.2-0.8Cr0.1-0.5Ox as the catalyst. Preferably, hydrocarbons are preferentially oxidized relative to carbon monoxides or nitrogen oxides. For producing an oxidation catalyst for internal combustion engines, a mixed oxide made of cerium oxide, titanium oxide, chromium oxide, and optionally other metal oxides is fixed to a metallic or oxide or carbide, high temperature-stable molded body or an oxide ceramic, wherein the oxide ceramic is fixed to a molded body. Preferably, here the molded body is a wire mesh or a honeycomb structure, or the oxide ceramic on which the mixed oxide is fixed is a wash coat. Within a combustion chamber and an exhaust-gas pipe or exhaust-gas return pipe connected to this combustion chamber, a mixed oxide is fixed based on cerium oxide, titanium oxide, and chromium oxide as an oxidation catalyst.
US08753989B2
High tensile stress in a deposited layer, such as a silicon nitride layer, may be achieved utilizing one or more techniques employed either alone or in combination. In one embodiment, a silicon nitride film having high tensile stress may be formed by depositing the silicon nitride film in the presence of a porogen. The deposited silicon nitride film may be exposed to at least one treatment selected from a plasma or ultraviolet radiation to liberate the porogen. The silicon nitride film may be densified such that a pore resulting from liberation of the porogen is reduced in size, and Si—N bonds in the silicon nitride film are strained to impart a tensile stress in the silicon nitride film. In another embodiment, tensile stress in a silicon nitride film may be enhanced by depositing a silicon nitride film in the presence of a nitrogen-containing plasma at a temperature of less than about 400° C., and exposing the deposited silicon nitride film to ultraviolet radiation.
US08753986B2
A deposition for producing a porous organosilica glass film comprising: introducing into a vacuum chamber gaseous reagents including one precursor of an organosilane or an organosiloxane, and a porogen distinct from the precursor, wherein the porogen is aromatic in nature; applying energy to the gaseous reagents in the chamber to induce reaction of the gaseous reagents to deposit a film, containing the porogen; and removing substantially all of the organic material by UV radiation to provide the porous film with pores and a dielectric constant less than 2.6.
US08753983B2
A method includes providing a silicon-containing die and providing a heat sink having a palladium layer over a first surface of the heat sink. A first gold layer is located over one of a first surface of the die or the palladium layer. The silicon-containing die is bonded to the heat sink, where bonding includes joining the silicon-containing die and the heat sink such that the first gold layer and the palladium layer are between the first surface of the silicon-containing die and the first surface of the heat sink, and heating the first gold layer and the palladium layer to form a die attach layer between the first surface of the silicon-containing die and the first surface of the heat sink, the die attach layer comprising a gold interface layer having a plurality of intermetallic precipitates, each of the plurality of intermetallic precipitates comprising palladium, gold, and silicon.
US08753977B2
A method for manufacturing a semiconductor device includes dry etching an interlayer insulating layer provided on a foundation layer by using a mask having a plurality of first openings and a plurality of second openings arranged more closely than the first openings to form simultaneously a first hole reaching the foundation layer under each of the first openings and a second hole reaching the foundation layer under the second openings. The first hole reaches the foundation layer without contacting any other first holes. After starting of the dry etching, a plurality of holes are formed under each of the plurality of second openings, and with the progress of the dry etching, the plurality of holes are connected with each other at least at their upper parts including their open ends to form the second hole having an opening area larger than an opening area of the first hole.
US08753966B2
A method for fabricating a semiconductor device is provided, the method includes forming a plug conductive layer over an entire surface of a substrate, etching the plug conductive layer to form landing plugs, etching the substrate between the landing plugs to form a trench, forming a gate insulation layer over a surface of the trench and forming a buried gate partially filling the trench over the gate insulation layer.
US08753962B2
When a mixed gas of trichlorosilane and dichlorosilane is used as source gas, a silicon layer is epitaxially grown on a surface of a silicon wafer within a temperature range of 1000 to 1100° C., preferably, 1040 to 1080° C. When dichlorosilane is used as source gas, a silicon layer is epitaxially grown on a surface of a silicon wafer within a temperature range of 900 to 1150° C., preferably, 1000 to 1150° C. According to this, a silicon epitaxial wafer, which has low haze level, excellent flatness (edge roll-off), and reduced orientation dependence of epitaxial growth rate, and is capable of responding to the higher integration of semiconductor devices, can be obtained, and this epitaxial wafer can be used widely in production of semiconductor devices.
US08753955B2
A method of fabricating a nonvolatile memory device includes forming trenches in a substrate defining device isolation regions therein and active regions therebetween. The trenches and the active regions therebetween extend into first and second device regions of the substrate. A sacrificial layer is formed in the trenches between the active regions in the first device region, and an insulating layer is formed to substantially fill the trenches between the active regions in the second device region. At least a portion of the sacrificial layer in the trenches in the first device region is selectively removed to define gap regions extending along the trenches between the active regions in the first device region, while substantially maintaining the insulating layer in the trenches between the active regions in the second device region. Related methods and devices are also discussed.
US08753954B2
A semiconductor device containing a cylindrical shaped capacitor and a method for manufacturing the same is presented. The semiconductor device includes a plurality of storage nodes and a support pattern. The plurality of storage nodes is formed over a semiconductor substrate. The support pattern is fixed to adjacent storage nodes in which the support pattern has a flowable insulation layer buried within the support pattern. The buried flowable insulation layer direct contacts adjacent storage nodes.
US08753946B2
The present invention provides a method of manufacturing an electronic apparatus, such as a lighting device having light emitting diodes (LEDs) or a power generating device having photovoltaic diodes. The exemplary method includes depositing a first conductive medium within a plurality of channels of a base to form a plurality of first conductors; depositing within the plurality of channels a plurality of semiconductor substrate particles suspended in a carrier medium; forming an ohmic contact between each semiconductor substrate particle and a first conductor; converting the semiconductor substrate particles into a plurality of semiconductor diodes; depositing a second conductive medium to form a plurality of second conductors coupled to the plurality of semiconductor diodes; and depositing or attaching a plurality of lenses suspended in a first polymer over the plurality of diodes. In various embodiments, the depositing, forming, coupling and converting steps are performed by or through a printing process.
US08753941B1
An integrated circuit with a LV transistor and a high performance asymmetric transistor. A power amplifier integrated circuit with a core transistor and a high performance asymmetric transistor. A method of forming an integrated circuit with a core transistor and a high performance asymmetric transistor. A method of forming a power amplifier integrated circuit with an nmos core transistor and an nmos high performance asymmetric transistor, a resistor, and an inductor.
US08753934B2
Various embodiment integrate embedded dynamic random access memory with fin field effect transistors. In one embodiment, a first fin structure and at least a second fin structure are formed on a substrate. A deep trench area is formed between the first and second fin structures. A high-k metal gate is formed within the deep trench area. The high-k metal gate includes a high-k dielectric layer and a metal layer. A polysilicon material is deposited within the deep trench area adjacent to the metal layer. The high-k metal gate and the polysilicon material are recessed and etched to an area below a top surface of a substrate insulator layer. A poly strap is formed in the deep trench area. The poly strap is dimensioned to be below a top surface of the first and second fin structures. The first and second fin structures are electrically coupled to the poly strap.
US08753933B2
Methods of selectively forming a conductive material and methods of forming metal conductive structures are disclosed. An organic material may be patterned to expose regions of an underlying material. The underlying material may be exposed to a precursor gas, such as a platinum precursor gas, that reacts with the underlying material without reacting with the remaining portions of the organic material located over the underlying material. The precursor gas may be used in an atomic layer deposition process, during which the precursor gas may selectively react with the underlying material to form a conductive structure, but not react with the organic material. The conductive structures may be used, for example, as a mask for patterning during various stages of semiconductor device fabrication.
US08753931B2
The present disclosure provides a method of fabricating a semiconductor device. The method includes forming a first gate structure and a second gate structure over a substrate. The first and second gate structures each include a high-k dielectric layer located over the substrate, a capping layer located over the high-k dielectric layer, an N-type work function metal layer located over the capping layer, and a polysilicon layer located over the N-type work function metal layer. The method includes forming an inter-layer dielectric (ILD) layer over the substrate, the first gate structure, and the second gate structure. The method includes polishing the ILD layer until a surface of the ILD layer is substantially co-planar with surfaces of the first gate structure and the second gate structure. The method includes replacing portions of the second gate structure with a metal gate. A silicidation process is then performed to the semiconductor device.
US08753921B2
A method for producing a semiconductor device according to the present invention includes a step of sputtering a target (100A). The target (100A) includes a plurality of target tiles (11A) located while having a gap therebetween; a backing plate (15A) for supporting the plurality of target tiles (11A); and a bonding member (17A) provided between the backing plate (15A) and the plurality of target tiles (11A). The plurality of target tiles (11A) each contain In, Ga and Zn. When the target (100A) is seen in a direction normal thereto from the side on which the plurality of target tiles (11A) are located, the plurality of target tiles (11A) are each smaller than an insulating substrate (1), and the bonding member (17A) cannot be seen through the gap.
US08753920B2
Provided is a precursor composition for an oxide semiconductor. The precursor composition for the oxide semiconductor includes a metal complex compound formed by a metal ion and an organic ligand, wherein the precursor composition is represented by the following Formula 1. MAn (Formula 1) Herein, M is a metal ion, A is an organic ligand which includes α-substituted carboxylate, and n is a natural number.
US08753918B2
A method of forming a solar cell including: providing a semiconductor body including at least one photoactive junction; forming a semiconductor contact layer composed of GaAs deposited over the semiconductor body; and depositing a metal contact layer including a germanium layer and a palladium layer over the semiconductor contact layer so that the specific contact resistance is less than 5×10−4 ohms-cm2.
US08753917B2
A design structure embodied in a machine readable medium used in a design process includes a first dielectric layer disposed on an intermediary layer, a first conductive pad portion and a first interconnect portion disposed on the first dielectric layer, a second dielectric layer disposed on the first dielectric layer, a first capping layer disposed on the first interconnect portion and a portion of the first conductive pad portion, a second capping layer disposed on the first capping layer and a portion of the second dielectric layer, an n-type doped silicon layer disposed on the second capping layer and the first conductive pad portion, an intrinsic silicon layer disposed on the n-type doped silicon layer, and a p-type doped silicon layer disposed on the intrinsic silicon layer.
US08753915B2
The invention relates to the production of solar panels which comprise solar cells connected to one another. In this case, various layers are stacked onto one another, such as a film layer, bonding agent, insulating film, solar cells and a support layer. Combining all these layers to form the final panel is carried out on a carrier which stabilizes and supports the stack while it is conveyed past the various treatment stations. The turning over of the stack can also be carried out in a reliable manner by means of such a carrier without shifts between the various components with respect to one another occurring.
US08753911B2
LED devices incorporating diamond materials and methods for making such devices are provided. One such method may include forming epitaxially a substantially single crystal SiC layer on a substantially single crystal Si wafer, forming epitaxially a substantially single crystal diamond layer on the SiC layer, doping the diamond layer to form a conductive diamond layer, removing the Si wafer to expose the SiC layer opposite to the conductive diamond layer, forming epitaxially a plurality of semiconductor layers on the SiC layer such that at least one of the semiconductive layers contacts the SiC layer, and coupling an n-type electrode to at least one of the semiconductor layers such that the plurality of semiconductor layers is functionally located between the conductive diamond layer and the n-type electrode.
US08753910B2
A method of manufacturing a vertical structure light emitting diode device, the method including: sequentially forming a first conductivity type III-V group compound semiconductor layer, an active layer, and a second conductivity type III-V group compound semiconductor layer on a substrate for growth; bonding a conductive substrate to the second conductivity type III-V group compound semiconductor layer; removing the substrate for growth from the first conductivity type III-V group compound semiconductor layer; and forming an electrode on an exposed portion of the first conductive III-V group compound semiconductor layer due to the removing the substrate for growth, wherein the bonding a conductive substrate comprises partially heating a metal bonding layer by applying microwaves to a bonding interface while bringing the metal bonding layer into contact with the bonding interface.
US08753906B2
A method for manufacturing a structure having a textured surface, including a substrate made of mineral glass having a given texture, for an organic-light-emitting-diode device, the method including supplying a rough substrate, having a roughness defined by a roughness parameter Ra ranging from 1 to 5 μm over an analysis length of 15 mm and with a Gaussian filter having a cut-off frequency of 0.8 mm; and depositing a liquid-phase silica smoothing film on the substrate, the film being configured to smooth the roughness sufficiently and to form the textured surface of the structure.
US08753891B2
A method of particle separation, wherein a collimated light source operable to generate a collimated light source beam is provided. The collimated light source beam includes a beam cross-section. A body is provided, wherein the body defines a wall and a first channel in a first plane. The first channel includes a first channel cross-section, the first channel being oriented to receive the collimated light source beam such that the beam cross-section completely overlaps the channel cross-section. The collimated light source beam is transmitted through the channel. A fluid sample is transmitted through the channel, fluid sample including a plurality of particles of a same type. All of the particles of the plurality of particles are separated axially along the collimated light source beam. All of the particles of the plurality of particles are retained against the wall in the collimated light source beam.
US08753890B2
An apparatus and method for analyzing a biological fluid sample is provided. The method includes the steps of: a) providing an analysis cartridge having a channel and an analysis chamber, wherein the channel is in fluid communication with the analysis chamber and includes at least one hydrophobic interior wall surface; b) admixing one or more anti-adsorption agents with fluid sample disposed within the channel, wherein the anti-adsorption agents are operable to inhibit adsorption of fluid sample onto the interior wall surface of the channel; c) moving the fluid sample into the analysis chamber; and d) analyzing the sample within the analysis chamber.
US08753882B2
Described herein are methods and compositions for the treatment of respiratory diseases such as, for example, exercise induced pulmonary hemorrhage. The methods include the use of compositions comprising platelet enriched plasma, for example, platelet rich plasma and/or platelet poor plasma, for treatment of respiratory diseases in humans and animals, in particular, equines, by administration to the respiratory system.
US08753864B2
The present invention relates to recombinant N-glycosylated proteins, comprising one or more introduced N-glycosylated optimized amino acid sequence(s), nucleic acids encoding these proteins as well as corresponding vectors and host cells. In addition, the present invention is directed to the use of said proteins, nucleic acids, vectors and host cells for preparing medicaments. Furthermore, the present invention provides methods for producing said proteins.
US08753861B2
The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided.
US08753852B2
The present invention provides a novel nucleic acid sequence, designated LIP1, encoding a lipolytic enzyme and the corresponding encoded amino acid sequences. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding at least one novel lipolytic enzyme, recombinant lipolytic enzyme proteins and methods for producing the same.
US08753847B2
Compositions and methods are provided for selection and enrichment of a target gene from a library of polynucleotide sequences such as might be formed from a genome or by random mutagenesis of a genetic sequence. The selection and enrichment occurs in aqueous droplets formed in an emulsion that compartmentalize individual polynucleotides from the library or a plurality of polynucleotides that may include polynucleotides not derived from the library, transcription and translation reagents and optionally additional chemical and enzyme reagents. The selection and enrichment method utilizes a polynucleotide adaptor which when ligated to the polynucleotide fragment enables amplification to occur in the presence of an adaptor specific primer.
US08753841B2
DNA and recombinant DNA that encode a peptide-forming enzyme, a method for producing a peptide-forming enzyme, and a method for producing a dipeptide are disclosed. A method for producing a dipeptide includes producing a dipeptide from a carboxy component and an amine component by using a culture of a microbe belonging to the genus Sphingobacterium and having the ability to form the dipeptide from the carboxy component and the amine component, a microbial cell separated from the culture, treated microbial cell product of the microbe or a peptide-forming enzyme derived from the microbe.
US08753835B2
Provided is a microbial test unit for detecting microbes in a compressed gas. The microbial test unit includes a decompression region and a sampling region in fluid communication with the decompression region and separated from the decompression region by a plate. The decompression region and the sampling region define a flow path. An inlet communicates with the decompression region such that compressed gas entering the decompressing region is incident on the plate for effectuating decompression of the gas prior to the gas passing into the sampling region. The microbial test unit may be used in conjunction with a growth medium substrate to form a microbial test system. The microbial test unit provides the ability to test compressed gas directly input to the unit due to positive pressure from the compressed gas pushing the microbes onto the microbial growth substrate.
US08753830B2
Cdc25A is herein identified as a substrate for β-TrCP1- or β-TrCP2-mediated ubiquitination and subsequent degradation via the ubiquitin-proteasome pathway. In particular, it has been found that interfering with β-TrCP expression or function, or increasing β-TrCP degradation, leads to accumulation of Cdc25A in a cell. Since degradation of Cdc25A is a key feature of the response to DNA damage, leading to a stall in the cell cycle during which the cell can repair the damage, Cdc25A accumulation can abolish this response, thereby sensitizing the cell to DNA damage. Described herein are assays for identifying β-TrCP inhibitors, and method of using such inhibitors for modulating Cdc25A degradation, sensitization of tumor cells, and as adjuvants in cancer therapy based on DNA damaging agents.
US08753820B2
Methods for identifying compounds useful for treating diseases or conditions of the oral cavity are described herein.
US08753819B2
Nucleic acid amplification assays for mutations to two short sections of the fungal gene FKS1. Mutations in these target sequences have been shown to correlate with resistance to echinocandin-class drugs. Assays may include detection by sequencing or by labeled hybridization probes. Also, primers, probes and reagent kits for performing such assays.
US08753812B2
Methods for direct detection of chemical reactions are provided. Electric charge perturbations of the local environment during enzyme-catalyzed reactions are sensed by an electrode system with an immobilized target molecule. The charge perturbation caused by the polymerase reaction can uniquely identify a DNA sequence. The polymerization process generates local perturbations of charge in the solution near the electrode surface and induces a charge in a polarazible gold electrode. This event is detected as a transient current by a voltage clamp amplifier. Detection of single nucleotides in a sequence can be determined by dispensing individual dNTPs to the electrode solution and detecting the charge perturbations. Alternatively, multiple bases can be determined at the same time using a mix of all dNTPs with subsequent analysis of the resulting signal. This technique may be adapted to other reaction determinations, such as enzymatic reactions, other electrode configurations, and other amplifying circuits.
US08753810B2
Particular aspects provide methods for specific amplification of template DNA in the presence of potentially contaminating PCR products from previous amplification experiments. Particular embodiments comprise, in a first step, contacting DNA with a bisulfite solution, which sulfonates unmethylated (but not methylated) cytosines, resulting in cytosine deamination and generation of sulfonated uracil. Such sulfonation protects the template nucleic acid from being a target for the enzyme uracil-DNA-glycosylase (UNG), whereas any contaminating DNA, which contains unprotected unsulfonated or desulfonated uracils, is degraded enzymatically while the UNG is active. After UNG treatment and inactivation thereof, the sulfonated uracil bases are converted into uracil by desulfonation. Such aspects have substantial utility for decontamination of nucleic acid samples; e.g., for avoiding amplification of ‘carry over products’ in the context of DNA methylation analysis. In further aspects, the inventive methods can be generally used as simplified methods of bisulfite treatment.
US08753808B2
A platelet aggregation measuring method comprising: preparing a measurement sample which contains a sample and a reagent which includes a platelet activator; mixing the measurement sample at a first speed; mixing the measurement sample at a second speed which is greater than the first speed after mixing the sample at the first speed; obtaining optical information from the measurement sample while mixing the measurement sample at the second speed; and analyzing aggregation of platelets in the sample based on the optical information is disclosed. A platelet aggregation measuring apparatus is also disclosed.
US08753806B2
An organ protectant solution which is intravenously administerable includes a high concentration of cell impermeant molecules which have a charge and/or molecular weight which permit passage across a capillary endothelium and into an interstitial space in said subject but which are too large and/or charged to cross a cell plasma membrane such that said one or more cell impermeant molecules preferentially load into an extracellular fluid compartment can be used to to allow for improved organ harvesting from DCD and brain death donors for transplantation purposes and also can be used extend the “Golden Hour” for traumatic and hemorrhagic shock patients thereby allowing more time for those patients to reach a point of care facility to receive medical treatment.
US08753799B2
The present invention relates to a method for fabricating an LCD. The method includes fabricating a MAV layer on a glass substrate. The step of fabricating the MAV layer on the glass substrate comprises the steps of: (A) coating MAV organic monomers on the glass substrate; (B) patterning the MAV organic monomers through a photomask; and (C) curing the patterned MAV organic monomers. In accordance with a photo-curing material of the MAV layer, the fabricating method of the present invention has simple processes with low technical requirements.
US08753797B2
Methods and materials for making a semiconductor device are described. The method includes providing a substrate, forming a surface-modified middle layer (SM-ML) that includes a fluorine-containing material over the substrate, forming a photoresist layer over the SM-ML, exposing the photoresist layer to an exposure energy, and developing the photoresist layer.
US08753786B2
A light pattern exposure method is by irradiating ArF excimer laser light to a resist film through a halftone phase shift mask. The mask includes a transparent substrate and a pattern of halftone phase shift film of a material comprising a transition metal, silicon, nitrogen and oxygen and having an atomic ratio (Met/Si) of 0.18-0.25, a nitrogen content of 25-50 atom %, and an oxygen content of 5-20 atom %. The mask may be irradiated with ArF excimer laser light in a cumulative dose of at least 10 kJ/cm2.
US08753783B2
The invention provides a fuel cell comprising an anode in an anode region of the cell and a cathode in a cathode region of the cell, the anode being separated from the cathode by an ion selective polymer electrolyte membrane, the anode region of the cell being supplied in use thereof with an alcoholic fuel, the cathode region of the cell being supplied in use thereof with an oxidant, the cell being provided with means for generating an electrical circuit between the anode and the cathode and with a non-volatile redox couple in solution in flowing fluid communication with the cathode in the cathode region of the cell, the redox couple being at least partially reduced at the cathode in operation of the cell, and at least partially re-generated by reaction with the oxidant after such reduction at the cathode, the redox couple and/or the concentration of the redox couple in the catholyte solution being selected so that the current density generated by the cell in operation is substantially unaffected by the crossover of the alcoholic fuel from the anode region of the cell to the cathode region of the cell across the polymer electrolyte membrane.
US08753780B2
Disclosed is an electrode (30) (for example, a positive electrode for a lithium ion battery), wherein an active material layer (35) mainly composed of an electrode active material is supported by a metal collector (32). A barrier layer (33) containing a conductive material (330) and a water-insoluble polymer material (334) are formed on the surface of the metal collector (32). The conductive material (330) contains at least a first conductive powder (331) having a certain average particle diameter, and a second conductive powder (332) having an average particle diameter larger than that of the first conductive powder. The ratio of the first conductive powder (331) contained in the barrier layer (33) is higher than that of the second conductive powder (332).
US08753774B2
A method for manufacturing a negative electrode material for a secondary battery with a non-aqueous electrolyte, including coating a surface of a powder with 1 to 40 mass % carbon by heat CVD treatment under an organic gas and/or vapor atmosphere at a temperature between 800° C. and 1300° C., blending lithium hydride and/or lithium aluminum hydride with the carbon-coated powder; and heating the carbon-coated powder at a temperature between 200° C. and 800° C. to be doped with lithium at a doping amount of 0.1 to 20 mass %. The powder is composed of at least one of silicon oxide represented by general formula of SiOx (x=0.5 to 1.6) and a silicon-silicon oxide composite having a structure so that silicon particles having a size of 50 nm or less are dispersed to silicon oxide in an atomic order and/or a crystallite state, and having a Si/O molar ratio of 1/0.5 to 1/1.6.
US08753770B2
An electrode body used for an all solid state battery element, having a bipolar electrode basic structure having: a current collector, a cathode active material layer formed on one surface of the above-mentioned current collector, an anode active material layer formed on a surface of the above-mentioned current collector and formed in a position not overlapping with the above-mentioned cathode active material layer in a plan view, and a current collector exposed portion, formed between the above-mentioned cathode active material layer and the above-mentioned anode active material layer, and exposing both surfaces of the above-mentioned current collector.
US08753765B2
Provided is a secondary battery including a fuse part that can continually function as a fuse. In the state where a first short circuit plate contacts a connecting plate to form a short circuit, even when heat generated from the short circuit melts the first short circuit plate, a second short circuit plate contacts the connecting plate to maintain a short circuit state, so that the fuse part can continually function as a fuse. The secondary battery includes an electrode assembly, a case accommodating the electrode assembly, a cap assembly including a cap plate sealing the case and having a short circuit hole, and a short circuit assembly including a first short circuit plate, a second short circuit plate, and a connecting plate. The first short circuit plate is disposed in the short circuit hole. The second short circuit plate contacts a lower part of the first short circuit plate. The connecting plate is spaced apart from the cap plate and is disposed outside the cap plate to cover the short circuit hole.
US08753764B2
A safe battery assembly structure comprises a plurality of secondary battery cells mounted on one side of a rack, and a positive guiding strip, a negative guiding strip, and a plurality of fuses mounted on the other side of the rack in such a manner that the secondary battery cells is electrically connected to the positive and negative guiding strips by the fuses and the connecting members, and each of secondary battery cells has its own fuse, so that the secondary battery cells are mounted on one side of the rack while the fuses and positive and negative guiding strips are all mounted on the other side of the rack, thus making it easy for visual checking, assembling, replacement, and maintenance of the components of the battery assembly, and also allowing a plurality of such battery assemblies to be safely arranged side by side or stacked on one another.
US08753762B2
A motor vehicle has an electric traction motor and a battery pack that provides power to the motor. The battery pack includes a plurality of battery cells. A thermal system includes a battery pack coolant loop, a cabin coolant loop, a power electronics coolant loop and a plurality of controllable valves controlled by a controller to select thermal modes by controlling flow paths of coolant in one or more of the coolant loops.
US08753757B2
An organic electroluminescence element comprising: an anode layer, a cathode layer, and an organic luminescence layer therebetween, the organic luminescence layer having a carbazole derivative with a glass-transition temperature of 110° C. or higher, and a phosphorescent dopant. This structure makes it possible to provide an organic electroluminescence element which can make use of the triplet exciton state of the carbazole derivative even at room temperature and which has a practical life and superior heat-resistance.
US08753734B2
A toe tap for a tap shoe is characterized by a blunt forward edge which defines a platform for a dance to utilize during dance steps, particularly when the dancer elevates to an elongated pointe position with supported by the tips of the toes. The tap includes a base which has a rear edge extending toward the ball area of the dance shoe and side edges which extend between the front and rear edges. The tap further includes constant perimeter around the side and front portions and a lip extending upwardly from the base at the constant perimeter to enable the dance to execute shuffle and other dance movements with the medial and lateral portions of the foot. A projection further extends from the lip at the front edge. The projection has a flat surface co-planar with the blunt front edge of the base to define a larger platform for supporting the toe tips of the dancer's foot.
US08753727B2
A polyester-carbamate polymer and coating compositions containing the polymer are provided. The polyester-carbamate polymer preferably includes a polyester-carbamate backbone and one or more blocked isocyanate groups. A coating composition is provided that preferably includes the polyester-carbamate polymer and a thermoplastic dispersion. In a preferred embodiment, the coating composition is an organosol.
US08753717B2
A film forming method for forming a thin film including boron, nitrogen, silicon, and carbon on a surface of a processing target by supplying a boron containing gas, a nitriding gas, a silane-based gas, and a hydrocarbon gas in a processing container in which the processing target is accommodated to be vacuum sucked includes: a first process which forms a BN film by performing a cycle of alternately and intermittently supplying the boron-containing gas and the nitriding gas once or more; and a second process which forms a SiCN film by performing a cycle of intermittently supplying the silane-based gas, the hydrocarbon gas, and the nitriding gas once or more. Accordingly, the thin film including boron, nitrogen, silicon, and carbon with a low-k dielectric constant, an improved wet-etching resistance, and a reduced leak current can be formed.
US08753712B2
The present method comprises providing a flexible web substrate (e.g., polymeric flexible web substrates) that forms at least part of a component of a device, coating so as to wet-out on and cover all or a substantial portion of a major surface on one side or both sides of the flexible web substrate with flowable polymeric material, while the flexible web substrate is moving in a down-web direction, and solidifying the polymeric material so as to form one cleaning layer on the major surface of one side or both sides of the flexible web substrate. The present invention can be utilized in a continuous in-line manufacturing process. In applications of the present invention where the flexible web substrate will not form a component of a device, the present invention broadly provides a method for cleaning particles from a flexible web of indefinite length. Each cleaning layer forms a substantially adhesive bond to the major surface that is readily removable without damaging or leaving a substantial residue of cleaning layer material on the major surface. A substantial number of the particles that were on this major surface are captured by and removable with the cleaning layer.
US08753711B2
The present techniques provide systems and methods for protecting electronic devices, such as organic light emitting devices (OLEDs) from adverse environmental effects. The edges of the devices may also be protected by a edge protection coating to reduce the adverse affects of a lateral ingress of adverse environmental conditions. In some embodiments, inorganic materials, or a combination of inorganic and organic materials, are deposited over the device to form a edge protection coating which extends approximately 3 millimeter or less beyond the edges of the device. In other embodiments, the device may be encapsulated with an organic region, and with an inorganic region, or the device may be encapsulated with inorganic materials, which may form the edge protection coating and may be combined with ultra high barrier technology. The coatings formed over the device may extend beyond the edges of the device to ensure lateral protection.
US08753709B2
Methods for making coatings on an implantable device, such as a drug-eluting stent. The coatings comprise a polymer and a drug in a crystalline or partially crystalline form. In addition, implantable devices produced by the methods and methods of using the coated implantable devices are described.
US08753708B2
A solventless method for forming a coating on a medical electrical lead is described. The method includes combining particles of a therapeutic agent with a polymeric material in a flowable form in the absence of a solvent to form a uniform suspension. A predetermined amount of the suspension is dispensed onto a portion of the lead and is then cured to form the therapeutic agent eluting layer. Additional layers such as a primer layer, fluoro-opaque layer and/or a topcoat layer can be formed using the solventless method. Employing a solventless method may avoid contraction of the layer being formed due to solvent evaporation during the curing process, and may facilitate greater control over the thickness of the therapeutic agent eluting coating.
US08753698B2
The present invention provides novel protein hydrolysates with anti-hypertensive properties, as well as food products and food supplements comprising these.
US08753695B1
A dry insect repellent includes a plurality of non-toxic natural essential oils and an amount of soybean oil, to facilitate even distribution of the active components throughout a dry carrier matrix. The dry carrier matrix facilitates storage, handling, and application of the dry insect repellent to a treatment area for the safe and effective control of mosquitoes and other pests.
US08753688B2
A bear bile macromolecular extract with anti-HCV virus function is disclosed. A preparation method comprises the following steps of: taking fresh bear bile or dissolving bear bile powder with water, centrifuging it by a molecular sieve filter membrane with molecular weight cut-off of 100,000 or an ultrafiltration membrane, filtering to obtain sediment, dissolving the sediment with water, adding the solution to sephadex column, separating the solution by using water or buffer as elution solvent, and freeze-drying the eluent to obtain the bear bile macromolecular extract. Experiments show that the bear bile macromolecular extract has anti-HCV virus function and can be used for treating hepatitis C.
US08753683B2
A solid pharmaceutical composition comprising a water-soluble bioactive material and an encapsulating material which is present in the composition in the form of continuous solid phase, and in which solid particles of the bioactive material are dispersed and encapsulated in the continuous solid phase of the encapsulating material, wherein each of the bioactive material and the encapsulating material is normally a solid at room temperature and the melting point of the encapsulating material is lower than the melting point of the bioactive material, the bioactive material being preferably a bisphosphonate, most preferably alendronate, and the encapsulating material includes an enhancer, preferably a mono- or di-glyceride, or an encapsulating surfactant, preferably a polyoxyethylene/polyoxypropylene block copolymer having surface active properties, and a process for preparing the composition in which solid particles of the bioactive material are mixed with and dispersed in the encapsulating material which is in molten (liquid) form; and cooling the molten form of the encapsulating material to form a solid pharmaceutical composition having the solid particles of the bioactive material dispersed and encapsulated in a continuous solid phase of the encapsulating material.
US08753681B2
The invention relates to a pharmaceutical composition, which comprises at least one active agent and which further comprises a binder and/or a retarding agent, wherein the binder swells in an acidic medium, and the retarding agent retards the release of the active agent in an acidic or alkaline medium.
US08753676B2
A new method for the preparation of microencapsulated essential oils is disclosed. The microcapsules containing essential oils or a formulation containing thereof may be used for various non-agricultural applications.
US08753651B2
Precipitated bacterial capsular polysaccharides can be efficiently re-solubilized using alcohols as solvents. The invention provides a process for purifying a bacterial capsular polysaccharide, comprising the steps of (a) precipitation of said polysaccharide, followed by (b) solubilization of the precipitated polysaccharide using ethanol. CTAB can be used for step (a). The material obtained, preferably following hydrolysis and sizing, can be conjugated to a carrier protein and formulated as a vaccine. Also, in vaccines comprising saccharides from the serogroups A and C, the invention provides that the ratio (w/w) of MenA saccharide:MenC saccharide is >1.
US08753650B2
The invention provides proteins from Staphylococcus aureus including amino acid sequences and the corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies and also as targets for antibiotics.
US08753640B2
The technology described herein relates to antibodies and/or polypeptides which bind to MIC and inhibit MIC shedding. Methods of using such antibodies and/or polypeptides for the treatment of cancer are also described herein.
US08753636B2
The present invention relates to a CD43 epitope expressed on human acute leukemia and lymphoblastic lymphoma cells and its use. More particularly, the present invention relates to a CD43 epitope expressed on human acute leukemia, lymphoblastic lymphoma cells, but not on mature hematopoietic cells, hematopoietic stem cells and non-hematopoietic cells, and to its diagnostic and therapeutic application on acute leukemia and lymphoblastic lymphoma.
US08753624B2
An isolated Lactobacillus paracasei strain GMNL-133 is disclosed, which was deposited in the China Center for Type Culture Collection (CCTCC) under the accession number of CCTCC M 2011331 is disclosed. The isolated Lactobacillus paracasei strain GMNL-133 is used for preparing a composition for use in the treatment of atopic dermatitis or other allergic diseases in an effective amount. And a composition for use in the treatment of atopic dermatitis or other allergic diseases comprises an effective amount of the Lactobacillus paracasei strain GMNL-133 is also disclosed.
US08753623B2
The present invention discloses isolated peptides encoding an antigen or fragments thereof from the N-terminus of hemagglutinin protein of influenza, methods for isolating such antigens and specific uses thereof. The peptide can be used as a vaccine to generate an antibody response that neutralizes influenza infectivity against a variety of influenza strains.
US08753620B2
According to an aspect of the invention, injectable bulking compositions are provided which contain the following: (a) fibers that are configured to prevent migration to locations in the body remote from the injection site, for example, because they have a minimum length that is sufficiently large to prevent migration of the fibers and/or because they have surface features that stimulate host tissue response to lock the fibers in position and (b) a carrier in an amount effective to render the composition injectable.
US08753619B2
Compositions provided by mixing a biotin-containing component and an avidin-containing component are useful as an adhesive or sealant for medical/surgical uses.
US08753616B2
The present invention concerns a process for permanent shaping of human hair used both for the permanent waving of human hair with an excellent waving effect as well as for the straightening of curled hair. Accordingly, the first object of the present invention is a process for permanent shaping hair wherein an aqueous composition comprising at least one inorganic salt is applied onto hair and optionally processed up to 20 min and optionally rinsed off and subsequently a composition comprising at least one reducing agent is applied and rinsed off from hair after a processing time of 1 to 30 min and at a temperature of 20 to 45° C. and a composition comprising at least one oxidizing agent is applied and processed for 1 to 20 min at a temperature range of 20 to 45° C. and rinsed off from hair.
US08753609B2
A standardized, edible food containing a label for use in the measurement of gastric emptying by the quantification of marker excreted in the breath of the patient and methods of making the same using fluid bed granulation processing.
US08753608B2
There is provided a gelatin-ICG complex that can suppress leakage of ICG included therein. The complex has a gelatin derivative including at least one of a phospholipid covalently bonded to a gelatin or a cholesterol covalently bonded to a gelatin, and indocyanine green.
US08753594B1
This invention relates to a method for preparing a lithium aluminate intercalate (LAI) matrix solid and methods for the selective extraction and recovery of lithium from lithium containing solutions, including brines. The method for preparing the LAI matrix solid includes reacting aluminum hydroxide and a lithium salt for form the lithium aluminate intercalate, which can then be mixed with up to about 20% by weight of a polymer to form the LAI matrix.
US08753589B2
Methane reacts with steam generating carbon monoxide and hydrogen in a first catalytic reactor; the resulting gas mixture undergoes Fischer-Tropsch synthesis in a second catalytic reactor. In the steam/methane reforming, the gas mixture passes through a narrow channel having mean and exit temperatures both in the range of 750° C. to 900° C., residence time less than 0.5 second, and the channel containing a catalyst, so that only reactions having comparatively rapid kinetics will occur. Heat is provided by combustion of methane in adjacent channels. The ratio of steam to methane may be about 1.5. Almost all methane will undergo the reforming reaction, almost entirely forming carbon monoxide. After Fischer-Tropsch synthesis, the remaining hydrogen may be fed back to the combustion channels. The steam for the reforming step may be generated from water generated by the chemical reactions, by condensing products from Fischer-Tropsch synthesis and by condensing water vapor generated in combustion.
US08753584B2
An electroosmotic (EO) pump is provided that includes a housing having a pump cavity, a porous core medium and electrodes. The porous core medium is positioned within the pump cavity to form an exterior reservoir that extends at least partially about an exterior surface of the porous core medium. The porous core medium has an open inner chamber provided therein. The inner chamber represents an interior reservoir. The electrodes are positioned in the inner chamber and are positioned proximate the exterior surface. The electrodes induce flow of a fluid through the porous core medium between the interior and exterior reservoirs, wherein a gas is generated when the electrodes induce flow of the fluid. The housing has a fluid inlet to convey the fluid to one of the interior reservoir and the exterior reservoir. The housing has a fluid outlet to discharge the fluid from another of the interior reservoir and the exterior reservoir. The housing has a gas removal device to remove the gas from the pump cavity.
US08753582B2
Disclosed is an apparatus that is used for detecting liquids or substances from liquids and includes a plunger that has a porous plunger layer which is pressed onto a sensor array. Each sensor of the sensor array is surrounded by elevations which spatially separate the sensors from each other like walls. In at least one embodiment, when the plunger layer is pressed onto the sensor array, the walls are pressed into the pores of the plunger layer. Liquid-tight connections are created between the walls and the plunger layer while liquid remains over the sensors. The liquid can be measured. In at least one embodiment, when there is direct mechanical contact between the plunger layer and the sensors, the liquid over the sensors is located in open pores on the surface of the plunger layer. No liquid flows between the pores and across the walls when pressure is applied to the plunger layer such that closed reaction chambers are created.
US08753576B2
A tube reactor having a substantially tubular body portion including a conical section, an entry port, an opposing exit port, and an axis extending between the ports through the body portion. The tubular body portion being rotatable about the axis. At least one reactant can be fed into the tubular body portion and directed toward the conical section. An inner surface of the tubular body portion receives the reactants from the conical section, and processes the reactants. An insert may be positioned within the tubular body portion to further process the reactants along the inner surface. A rotating reservoir having a damper can be coupled to the rotating tubular body portion. The damper receives the processed reactants from the inner surface of the tubular body portion, and guides the processed reactants into the rotating reservoir to minimize turbulence. The rotating reservoir then separates the processed reactants by density.
US08753563B2
A system for adding gas to and transferring molten metal from a vessel and into one or more of a ladle, ingot mold, launder, feed die cast machine or other structure is disclosed. The system includes at least a vessel for containing molten metal, an overflow (or dividing) wall, a device or structure, such as a molten metal pump, for generating a stream of molten metal, and one or more gas-release devices.
US08753556B2
The present invention relates to an educational method and apparatus for the instruction of basic scientific principles relating to mining. The apparatus consists of a kit for science instruction that comprises a topographic mold, casting compound, and one or more components simulating materials found in nature beneath the surface of the earth. The kit may include a tool for obtaining core samples of the resulting topographic model and may include a topographic map. The components of the kit may be used in conjunction with weight measurement tools.
US08753552B2
A heat sink using porous graphite having graphite particle-stacked porous graphite is provided. The heat sink may provide good heat conductivity and improve strength of carbon foam. Also, a manufacturing method of porous graphite is provided.
US08753548B2
A composite oxide sintered body includes In, Zn, and Sn, and has a relative density of 90% or more, an average crystal grain size of 10 μm or less, and a bulk resistance of 30 mΩcm or less, the number of tin oxide aggregate particles having a diameter of 10 μm or more being 2.5 or less per mm2 of the composite oxide sintered body.
US08753547B2
A thermoelectric material that comprises a ternary main group matrix material and nano-particles and/or nano-inclusions of a Group 2 or Group 12 metal oxide dispersed therein. A process for making the thermoelectric material that includes reacting a reduced metal precursor with an oxidized metal precursor in the presence of nanoparticles.
US08753545B2
Composite particles that include an electrochemically active metal phase, an insulating phase, and a conducting phase are provided that are useful active materials in negative electrodes for lithium-ion electrochemical cells. The electrochemically active phase includes silicon. Lithium-ion electrochemical cells are provided that include the provided composite composite particles as active materials in negative electrodes as well as methods of making the provided composite particles.
US08753543B2
The present invention provides a chemically functionalized submicron graphitic fibril having a diameter or thickness less than 1 μm, wherein the fibril is free of continuous thermal carbon overcoat, free of continuous hollow core, and free of catalyst. The fibril is obtained by splitting a micron-scaled carbon fiber or graphite fiber along the fiber axis direction. These functionalized graphitic fibrils exhibit exceptionally high electrical conductivity, high thermal conductivity, high elastic modulus, high strength and good interfacial bonding with a matrix resin in a composite. The present invention also provides several products that contain submicron graphitic fibrils: (a) paper, thin-film, mat, and web products; (b) rubber or tire products; (c) energy conversion or storage devices, such as fuel cells, lithium-ion batteries, and supercapacitors; (d) adhesives, inks, coatings, paints, lubricants, and grease products; (e) heavy metal ion scavenger; (f) absorbent (e.g., to recover spill oil); (g) sensors; (h) friction and brake components; (i) radiation-shield components; (j) catalyst carrier; and (k) composite materials.
US08753542B2
Disclosed herein are thermally stable conducting polymers prepared by template polymerization of a conducting monomer in the presence of a sulfonated poly(amic acid). The resulting conducting polymer-sulfonated poly(amic acid) complex can be thermally converted to a conducting polymer-sulfonated poly(imide) complex having high thermal stability and high conductivity. Also disclosed are articles prepared from the thermally stable conducting polymer.
US08753541B2
The molecule is prepared by capping phospholipid on a single gold nanoparticle (GNP). Since the thiol-related molecule bounded on GNP shows the characteristic of surface-enhanced Raman scattering (SERS), the phospholipid-capped gold nanoparticle (PLGNP) can be formed as a nanoprobe applied on the detection device integrating optics and chemistry and used in the fields of biomedicine, medical diagnosis and environment for detecting, such as solutions containing salts or proteins.
US08753540B2
The present invention relates to a method for preparing graphene, and more particularly to a method of preparing graphene sheets, which can prepare graphene sheets from a turbostratic graphitic structure such as carbon fiber in higher yield without using a strong oxidizing agent, and to graphene sheets prepared thereby.
US08753527B2
A plasma etching method uses a plasma etching apparatus including a process chamber, a susceptor, a microwave supplying portion, a gas supplying portion, an evacuation apparatus, a bias electric power supplying portion that supplies alternating bias electric power to the susceptor, and a bias electric power control portion that controls the alternating bias electric power, wherein the bias electric power control portion controls the alternating bias electric power so that supplying and disconnecting the alternating bias electric power to the susceptor are alternately repeated to allow a ratio of a time period of supplying the alternating bias electric power with respect to a total time period of supplying the alternating bias electric power and disconnecting the alternating bias electric power to be 0.1 or more and 0.5 or less.
US08753511B2
Apparatus for integrated biological wastewater treatment and clarification including a tank having a wastewater inlet for receiving wastewater to be treated and having a treated, clarified wastewater outlet for providing treated, clarified wastewater for use, the tank having an upper turbulence region, a lower solids settling region below the upper turbulence region and a sludge collection region below the lower solids settling region, a multiplicity of biomass carriers disposed in the upper turbulence region, a gas diffuser assembly arranged generally between the upper turbulence region and the lower solids settling region for providing gas bubbles which move upwardly through the wastewater and the biomass carriers in the upper turbulence region, providing turbulence and oxygen and a sludge removal conduit communicating with the sludge collection region for removal of sludge therefrom.
US08753510B2
A fluid pressure vessel has a chamber with an inlet and outlet with a nested primary and secondary filter bag disposed such that the primary bag communicates exclusively with the inlet, and flow through the primary bag flows through the secondary bag before the outlet. The primary bag is disposed in a first rigid porous basket and the bag rim seals against a flange on the first basket. The secondary filter bag surrounds the first basket and the rim of the secondary bag is sealed around the flange of first basket. A second rigid porous basket surrounds the secondary filter bag and is sealed on the rim of the secondary filter bag and is sealed against the inner periphery of the pressure chamber by an O-ring.
US08753509B2
Embodiments of the present invention relate to a filtration module and/or a novel method of making a frameless filtration module for water or wastewater treatment that can produce filtrate that is free of particles, reduce precipitated hardness, colloids and organic compounds. The designed apparatus, which is either encapsulated or in cassette form, can be assembled and disbanded easily to suit diverse process requirements. The module configuration and assembly also helps in clean-in-place, repair or replacement activities to be performed in situ.
US08753506B2
Disclosed herein is an apparatus for filtering sewage and wastewater. The filtering apparatus has a vertical structure including a filtering belt comprising a filter bag or a filter mesh that can filter out fine impurities. For this, the filtering apparatus includes a drive motor that receives power to drive the apparatus, an upper drive drum that is operated by the drive motor, a lower rotating drum that is interlocked with the upper drive drum, and a filtering belt that is wound and rotated around the upper drive drum and the lower rotating drum. The filtering apparatus cannot only filter out fine impurities less than from 0.1 mm to 0.2 mm but also separate earth and sand, unlike conventional filtering apparatuses that cannot conduct them. Furthermore, because the filtering apparatus can be placed upright or inclined at a predetermined angle, it can be used in a water inlet passage that is 4 m to 5 m underground, and impurities filtered out from water can be transferred to a height higher than 10 m above ground.
US08753502B1
This procedure uses a low carbon fuel with a FCC Catalyst Heater-Fuel Gas/Catalyst Combustion Chamber. The low carbon content fuel source will minimize CO2 emissions while satisfying unit heat balance. This will further reduce coke yield and CO2 emissions while improving energy efficiency.
US08753493B2
The present invention relates to an apparatus for measuring biomaterial and a method for manufacturing thereof. The apparatus of the present invention comprises: a first substrate having a recess in one side thereof; a second substrate having a plurality of reaction electrodes where a biochemical reaction of a biomaterial occurs, and a plurality of delivery electrodes delivering signals from the reaction to a detector; and reaction reagents located in the recess causing the reaction with the biomaterial. The second substrate is attached to the first substrate such that a portion of the recess forms a sample-inlet, the recess cooperates with at least one edge of the second substrate to form at least one vent slit, and the reaction electrodes are directed toward the recess. Such apparatus of the present invention enables air in the capillary to be thoroughly and quickly discharged to the outside with biomaterial-introduction, thereby increasing the speed of the biomaterial-introduction.
US08753488B2
An apparatus for growing nano-clusters includes a pair of electrodes separated by an electrode pair spacing and a field generation module that generates a corona discharge across the electrodes. The corona discharge generates an electromagnetic field near the electrodes. A voltage potential across the electrodes is a medium voltage. The field generation module includes a medium voltage module that generates a medium voltage waveform, which is transmitted to the electrodes to generate the corona discharge. The field generation module includes a broad frequency generation module that generates a broad spectrum of frequencies within the medium voltage waveform. A raw material feeder module feeds particles of a raw material through the electromagnetic field. The electromagnetic field with the broad spectrum of frequencies is operative to separate at least a portion of the raw material fed through the electromagnetic field into free atoms.
US08753484B2
A process comprising treating a lignocellulosic material preferably pulp in the presence of a transition metal catalyst with a oxidizing agent selected from a group consisting of hydrogen peroxide, hypochlorite, hypochlorous acid and any combination thereof to form a treated lignocellulosic material having a viscosity equal to or less than about 17 cp and having reducing functional groups selected from the group consisting of aldehyde and aldehyde type functional groups at the C6 and C1 positions but predominating at the C1 position.
US08753480B2
The current invention includes a composition having stability additives of selected inorganic salts and/or organic incorporated into an aldehyde-functionalized polymer product. The stability additive can be post added to the finished polymer product, added to the reaction vessel prior to inducing functionalization of the non-functionalized polymer, or added at any stage during the functionalization reaction. Methods for forming the composition and using the composition to produce a cellulosic fiber-based medium are also disclosed.
US08753475B2
Provided is a plasma processing apparatus featuring highly improved plasma ignition property and ignition stability by defining a positional relationship between a dielectric and the slots. A plasma processing apparatus 11 includes a processing chamber 12 having a top opening; a dielectric 15 which has inclined surfaces 16a and 16b on a bottom surface thereof so that a thickness dimension is successively varied, and is disposed so as to close the top opening of the processing chamber 12; and an antenna 24disposed on a top surface of the dielectric 15, for supplying microwave to the dielectric 15, thereby generating plasma at the bottom surface of the dielectric 15. Further, the antenna 24 is provided with a plurality of slots 25positioned uprightly above the inclined surfaces 16a and 16b.
US08753474B2
Embodiments of the present invention relate to method and apparatus for providing processing gases to a process chamber with improved plasma dissociation efficiency. One embodiment of the present invention provides a baffle nozzle assembly comprising an outer body defining an extension volume connected to a processing chamber. A processing gas is flown to the processing chamber through the extension volume which is exposed to power source for plasma generation.
US08753470B2
Analyte sensors for determining the concentration of an analyte in a sample. The sensors have a sample chamber having an inlet with a projection extending from an edge of the sensor for facilitating flow of sample into the sample chamber.
US08753466B2
In one embodiment, a method of making disposable absorbent garments includes providing an outer cover web having front and back waist edges; attaching elastomeric front and back body panel webs to the outer cover web. The front and back body panel webs comprise an elastomeric film laminate. Portions of the outer cover web are removed to define a series of spaced apart holes. The elastomeric front body panel web defines a front body panel web width that extends at least 50% of a shortest distance extending from the front waist edge to each hole, and the elastomeric back body panel web defines a back body panel width that extends at least 50% of a shortest distance extending from the back waist edge to each hole.
US08753465B2
A method of fabricating a composite material part such as a link. The method comprises the successive operations of applying reinforcing fiber layers (14a, 14b, 14c) that are braided around a mandrel over all or part of the length of the mandrel, the layers being superposed one on another. The method includes a step of cutting an intermediate reinforcing fiber layer (14a, 14b, 14c) after it has been applied, a step of withdrawing a cut portion prior to applying the following braided layer (14b, 14c), thereby locally building up an extra thickness of reinforcing layers on each portion of the cut layer that has remained in place, the extra thickness constituting local reinforcement of the part. Resin is subsequently injected into the various braided layers prior to the resin being polymerized in order to prepare a blank. The method applies in particular to the field of aviation.
US08753462B2
Disclosed is a method of manufacturing a nonshrinking multilayer ceramic substrate. The method includes forming at least one conductive via and an electrode pattern in at least one of a plurality of ceramic green sheets, laminating the ceramic green sheets to form a ceramic laminate, selectively forming a shrinkage inhibiting thin film of sinter-resistant powder on a region including the conductive via and a periphery thereof in at least one of two surfaces of the ceramic laminate using aerosol deposition, disposing a shrinkage inhibiting green sheet for suppressing the shrinkage of the ceramic laminate on at least one of the two surfaces of the ceramic laminate including the shrinkage inhibiting thin film to form a non-sintered multilayer ceramic substrate, and sintering the non-sintered multilayer ceramic substrate.
US08753458B2
The three dimensional (3-D) locations of splices in pre-preg tows placed by an automatic fiber placement machine to form a laminated composite structure are mapped to allow visualization of alignment patterns in the splices.
US08753456B2
Forming a 3D topology by forming a monolayer of nano-particles on a stainless steel surface, masking the stainless steel surface forming at least one unmasked regions, the unmasked region having an average density of nano-particles less than a critical average density, and introducing a plurality of exogenous atoms into the stainless steel surface only in the unmasked regions, the exogenous atoms causing the associated metal lattice to expand and harden and have an increase corrosion resistance, thereby selectively forming a 3D topology on the stainless steel surface.
US08753455B2
A wire for use in a brazing or soldering operation is provided. The wire preferably includes a body formed of a metallic material. A flux solution is provided within a channel along at least a portion of the length of the body and a surface of the flux solution is exposed. The body is preferably formed into an annular ring having an inner wall and an opposing outer wall. The flux solution preferably includes a solvent, a polymer dissolved in the solvent, and a powdered flux added to the polymer solution.
US08753451B2
Liquid hydrocarbon storage tanks are cleaned by transferring the most contaminated lower fuel layer to an external vessel on a treatment truck where separation into a contaminants portion and a fuel portion occurs. The remnant fuel in the storage tank is cleaned by multiple passes through an external circuit on the truck. The fuel from the vessel is sometimes returned to the remnant fuel to be cleaned. The contaminants are discarded. The initial separation shortens the cleaning cycle. A flexible dip tube stiffened by a guide rod allows probing of the storage tank floor.
US08753441B2
A phase change ink composition suitable for ink jet printing, including printing on coated paper substrates. In embodiments, the phase change ink composition comprises both a crystalline compound and an amorphous compound which are derived from bio-renewable and recycled starting materials. The composition provides for a robust, rapid crystallization ink composition.
US08753437B2
Disclosed is a dry CO2 capturing device with improved energy efficiency, which utilizes a difference in temperature between a regeneration operation of isolating CO2 from an sorbent containing CO2 absorbed therein and a pre-treatment operation of allowing H2O to be adsorbed to CO2. The dry carbon dioxide (CO2) capturing device, includes a recovery reactor for recovering CO2, a recovery cyclone for discharging a gas while separating the CO2-captured solid sorbent only, a regenerator for receiving the CO2-captured solid sorbent and separating CO2 captured in the solid sorbent, and a pre-treatment reactor for cooling the solid sorbent free from CO2, wherein a first heat exchanger is provided between the recovery cyclone and the regenerator to pass the CO2-captured solid sorbent therethrough, and a second heat exchanger is provided between the pre-treatment reactor and the regenerator to pass the solid sorbent free from CO2 therethrough. The first and second heat exchanger include a first and second heat exchange jacket mounted thereon which are connected to each other in a closed loop state.
US08753434B2
Filter media that includes activated carbon particulates and zinc oxide particles disposed on surfaces of the activated carbon particulates. The zinc oxide particles have an average crystallite dimension that is not greater than about 50 nm.
US08753422B2
A method is disclosed for producing cast iron or semi steel with reducing gas in a high pressure refractory lined shaft furnace using minimal or no coke Iron ore and slag are fed into the operative top zone of the shaft furnace while reducing gas which is generated in a refractory lined gasifier using preheated oxygen is fed through tuyeres at the operative bottom and middle zones. The shaft furnace is operated at a high pressure to increase productivity and to facilitate use of the spent reducing gas downstream. Excess oxygen is fed into the shaft furnace to reduce the carbon content in the molten iron and generate semi steel. The size of the furnace is reduced. The method is economical.
US08753418B2
A nanopowder and a method of making are disclosed. The nanopowder may be in the form of nanoparticles with an average size of less than about 200 nm and contain a reactive transition metal, such as hafnium, zirconium, or titanium. The nanopowder can be formed in a liquid under sonication by reducing a halide of the transition metal.
US08753412B2
An outer blade cutting wheel comprising an annular thin disc base of cemented carbide and a blade section is manufactured by disposing permanent magnet pieces on the side surfaces and inward of the outer periphery of the base to produce a magnetic field, providing magnetic coated diamond and/or CBN abrasive grains such that the magnetic field may act on the grains, causing the grains to be magnetically attracted to the base outer periphery, and electroplating or electroless plating whereby the abrasive grains are bound to the base outer periphery to form the blade section.
US08753409B2
A method of manufacturing a solid electrolytic capacitor includes steps (a) and (b). In the step (a), an element body is placed on a surface of a first terminal component part after applying a first conductive adhesive to the surface of the first terminal component part. The element body is placed with a third side surface of the element body facing the surface of the first terminal component part such that the first conductive adhesive is interposed between the third side surface of the element body and the first terminal component part. The step (b) is performed after the step (a). In the step (b), a second conductive adhesive is applied to fill space between a second terminal component part and a second side surface of the element body such that an opening is not filled with the second conductive adhesive.
US08753406B2
A delivery device for an osteochondral graft comprising a tube, a plunger and a graft retention assembly is disclosed. The tube has a bore having an inside diameter and extends from a proximal end to a distal end. The inside diameter of the bore is sufficient to accept an osteochondral graft of a desired diameter. The tube has a set of apertures located adjacent the distal end of the tube. The plunger is slidably disposed within the bore of the tube. The graft retention assembly comprises a collar and a set of tabs. The graft retention assembly is attached to the tube such that the tabs are disposed within the apertures of the tube. The tabs are biased towards each other but are capable of being displaced away from each other to receive or release the osteochondral graft.
US08753402B2
A two piece humeral component for use in joint arthroplasty which is adapted to be implanted into a joint and engaged by a socket component of the joint. The joint component includes a body having a first articulating surface and a second medial surface opposite the first articulating surface. The first articulating surface is adapted to be engaged by the socket and the second medial surface is adapted to be secured to mounting portion. The mounting portion has a first surface and a second medial surface. The first surface is adapted to be fixably engaged to the second mounting portion of the humeral component. The second medial surface is adapted to be secured to the humerus. A peg which has a first end adapted to engage a cavity found in the humerus is disposed on the mounting portion's second medial surface.
US08753389B1
A packaged, sterilized intraocular lens prepared by a process comprising providing a hydrophobic acrylic, or low water acrylic, intraocular lens and positioning the acrylic lens in a lens enclosure with an aqueous solution to provide a lens package. The lens package is then heated to a temperature sufficient for sterilization, however, the heating of the lens package must begin before the acrylic lens reaches an equilibrated, hydrated state following contact of the lens with the aqueous solution. The resulting sterilized acrylic intraocular lens will have less than sixty percent of total volume of disc-like features, or less than forty percent of total volume of water vacuoles, after 60 days following sterilization compared to an acrylic lens of the same composition, which was sterilized under the same conditions, but in an equilibrated, hydrated state.
US08753382B2
The present invention relates to a portable apparatus for warming biocompatible fluids for use in the treatment of injured patients and a method of heating a biocompatible fluid to treat a patient experiencing hypothermia. The present invention may be used to warm intravenous fluids for trauma resuscitation or to warm air from a ventilator circuit. The portable nature of the present invention makes it highly suitable for field applications, such as a forward surgical hospital near a combat zone.
US08753371B1
Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measureable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.
US08753369B2
A mechanism for removing a fluid-filled object from a patient. The apparatus includes a deflation tube with a puncture member at one end of the tube for piercing a hole in the object wall. The apparatus includes a retrieval mechanism slidable within the deflation tube lumen. The retrieval mechanism includes an expansion element that is expandable when positioned within the object from a first configuration with a dimension less than that of the deflation tube lumen to a second or deployed configuration with a dimension that is greater than an outer dimension of the puncture member. The expansion element contacts an inner surface of the inflatable object as the deflation tube and retrieval mechanism are withdrawn from the body cavity. The expansion element may be a T-bar, a foldable anchor, an inflatable member, or another expandable form.
US08753368B2
The present disclosure relates to a sheath system for enabling access through an opening in the body of a patient is provided. The sheath system includes a dilation assembly having a radially expandable tubular sheath defining a lumen having a first cross-sectional area when in a non-expanded condition, and a handle assembly operatively coupled to a proximal end of tubular sheath, the handle assembly defining an aperture formed therein, and a first thread defined on the handle in the aperture thereof. The sheath system further includes an expansion assembly including a tubular member defining a lumen having a second cross-sectional area which is larger than the first cross-sectional area of the tubular sheath of the dilation assembly and having an outer surface defining a second thread, the second thread being arranged for engaging the first thread.
US08753366B2
The inventions described in this patent application include i) a torqueable introducer sheath which is useable in conjunction with a transvascular passageway forming catheter to effect precise rotational control of the catheter; ii) an anchorable guide catheter which is useable in conjunction with an intravascular imaging catheter and a transvascular passageway-forming catheter to effect precise positioning and aiming of the passageway-forming catheter; iii) a passageway forming catheter having a torqueable proximal portion to facilitate precise rotational positioning of the distal portion of the catheter; iv) a deflectable-tipped passageway forming catheter, v) various markers and other apparatus useable in conjunction with any of the passageway-forming catheters to facilitate precise positioning and aiming of the catheter, and vi) an apparatus which may be formed within a catheter to prevent a member, apparatus of flow of material from being inadvertently advanced through a lumen of the catheter.
US08753365B2
The present invention relates to an apparatus, device and a method for harvesting blood vessels, and in particular, to such an apparatus, device and method in which the internal mammary artery (IMA) is harvested for coronary artery bypass graft (CABG) surgery using a minimally invasive approach or a conventional procedure.
US08753364B2
Disclosed herein is a system for releasing a ligament. In one embodiment, the system includes a proximal handle, a tubular body, and a flexible body. The tubular body includes a proximal end and a distal end. The handle is coupled to the proximal end. The flexible body extends through the tubular body and includes a tissue cutting portion. The flexible body or tubular body is longitudinally displaceable to move the tissue cutting portion between a non-deployed state and a deployed state.
US08753350B2
A grabbing device includes a transparent flexible cup that can be placed adjacent to a selected region of an inner surface of a body cavity. The flexible cup is visually put in place by the surgeon, and a vacuum is applied to draw a selected amount of tissue into the flexible cup, so that it may, e.g., be excised. The device may also retrieve the tissue excised from the body cavity.
US08753342B2
A device for generating localized heating in a selected body tissue includes an applicator having a source of microwave radiation and an array of retractable needles arranged so as to extend from one face of the applicator and, in operation, to confine the irradiated microwave energy field emanating from the applicator. The device has application for controlling excessive bleeding from severed tissue during surgical procedures.
US08753338B2
An electrosurgical surgical instrument can comprise a handle and an end effector, wherein the end effector can comprise first and second jaws which can be opened and closed in order to capture tissue therebetween. In various embodiments, the first and second jaws can comprise one or more electrodes configured to apply a voltage across the tissue thereby causing current to flow through the tissue and, as a result, generate heat within the tissue. The surgical instrument can further comprise a fluid circulatory system embedded within at least a portion the end effector wherein, in at least one embodiment, the fluid can be dispensed from the fluid circulatory system and onto the jaws of the end effector and/or the tissue positioned between the jaws.
US08753335B2
A device for delivering therapeutic energy to tissue is provided. The device includes a housing and a rotating device coupled to the housing. The device includes a plurality of electrodes, each electrode including: (i) a proximal section longitudinally extending from within the housing to an exterior of the housing and having a longitudinal axis; (ii) an intermediate section extending from the proximal section; and (iii) a distal section extending longitudinally from the intermediate section. The rotating device is coupled to the proximal sections of the plurality of electrodes and adapted to rotate the distal section of the electrodes so that distance between at least two electrodes changes, so that the electrodes can be placed in a compact configuration or an expanded configuration to provide for a treatment region larger than the size of the opening for insertion.
US08753329B2
A guide catheter assembly includes an outer guide catheter and an inner catheter slidably and rotatably disposed in the outer guide catheter. The outer guide catheter has a proximal portion and a distal portion formed into a preformed shape including a curved segment. The preformed shape includes a first arc, a second arc, a third arc, a fourth arc, and a generally straight terminal portion. The preformed shape is generally a J-shape defining, a generally open arc.
US08753320B2
An apparatus for controlling fluid flow to provide long-term access to the vascular system, and methods of making the same, are disclosed. Exemplary embodiments of the present invention describe a wedge or other similarly shaped geometrical feature for fixing an elastic component and controlling an internal stress of the elastic component.
US08753312B2
A catheter assembly employs an outer catheter with a pre-formed distal end and an open lumen. An inner catheter having an open lumen and a pre-formed distal end is movably disposed within the outer catheter. Relative rotation and extension of the inner and outer catheters provides the distal end of the catheter assembly with an adjustable range of two- and three-dimensional shapes. The inner catheter can include sections of varying stiffness, such that extension of the inner catheter within the outer catheter modifies the shape of the outer catheter's pre-formed distal end. One or both of the outer and inner catheters includes an occlusion balloon attached to the distal end thereof. The adjustable shaping of the catheter assembly's distal tip provides an improved system for locating and cannulating cardiac venous structures, particularly the coronary sinus via the right atrium.
US08753303B2
A drainage stent delivery system including an elongate shaft of a medial device, a drainage catheter or stent, and a locking mechanism for selectively coupling the drainage stent to the elongate shaft. The drainage stent is selectively coupled to a distal portion of the elongate shaft such that the proximal end of the stent is positioned proximal of the distal end of the elongate shaft. The locking mechanism includes an engaging feature of the elongate shaft which engages a portion of the stent such that the stent may be selectively coupled to the elongate shaft through rotational motion of the elongate shaft relative to the stent. In some instances, the engaging feature of the elongate shaft may be a tab which extends into an opening of the stent.
US08753298B2
A support structure for fixating a patient to a treatment unit, and especially a support structure for fixating the patient to a cardiopulmonary resuscitation unit. An embodiment of the support structure comprises a back plate for positioning behind the patient's back posterior to the patient's heart and a front part for positioning around the patient's chest anterior to the patient's heart. Further, the front part can comprise two legs, each leg having a first end pivotably connected to at least one hinge and a second end removably attachable to the back plate. The front part can further be devised for comprising a compression/decompression unit arranged to automatically compress or decompress the patient's chest when the front part is attached to the back plate.
US08753296B2
A method of rehabilitation using an actuator type that includes a movement mechanism capable of applying a force that interacts with a motion of a patient's limb in a volume of at least 30 cm in diameter, in at least three degrees of freedom of motion of the actuator and capable of preventing substantial motion in any point in any direction in said volume, comprising: exercising a patient at a first place of rehabilitation selected from a bed, a wheel-chair, a clinic and a home, using an actuator of said actuator type which interacts with a motion of said patient; and second exercising said patient at a second place of rehabilitation selected from a bed, a wheel-chair, a clinic and a home using a second actuator of said actuator type which interacts with a motion of said patient; wherein said first exercising and said second exercising utilize a same movement mechanism design for moving the actuators.
US08753295B2
A method and system including an applicator for treating dermatological conditions such as warts is presented for applying ultrasonic energy from a specially-designed ultrasonic energy applicator designed for use with localized dermatological conditions to heat an affected localized region sufficiently to achieve a desired therapeutic result. Specific embodiments include temperature measurement and/or sensing and/or actuation by way of a temperature sensor coupled to the ultrasonic energy applicator. Also, a medicated ultrasound-compatible patch is disclosed for applying to a region of tissue to be treated and includes substances known to aid in the treatment of a condition and adapted for transmitting the ultrasound energy into the region of tissue.
US08753292B2
A method for locating a catheter tip within a human body is disclosed. An audio sensor is positioned at a site on the human body. An audio signal is detected by the audio sensor, and transmitted to an audio signal processing unit. The audio signal processing unit determines if the audio signal corresponds to a target location of the catheter tip, and transmits a notification signal to a user notification unit. An infusion of fluid or an audio emitting element can be used to generate the audio signal at the catheter tip.
US08753284B2
A device may include a vibration sensor configured to sense blood flow in a lumen of a person; a cuff coupled to the vibration sensor and configured to contact a limb of the person; a cuff pressurizer coupled to the cuff, the cuff pressurizer configured to adjust a compressive force of the cuff on the lumen; and an energy-generating apparatus coupled to the cuff, the energy-generating apparatus configured to generate energy from a depressurization of the cuff.
US08753283B2
Single- or dual-bladder devices for remote ischemic preconditioning and blood pressure monitoring are disclosed along with various oscillometry-based and other methods for detecting systolic and diastolic blood pressure while the ischemic preconditioning treatment is in progress. The devices and methods of the invention provide for delivery of ischemic preconditioning at the lowest effective cuff pressure while closely monitoring patient's hemodynamics. Advantageously, the device of the invention allows both ischemic preconditioning and blood pressure monitoring to be done on the same limb. Disposable battery-powered version of the device of the present invention is especially useful for emergency use with patients suffering from acute myocardial infarction, acute stroke, or acute trauma. Additional device configurations are described for use in a percutaneous intervention and vascular sealing settings.
US08753282B2
A blood pressure measurement apparatus detects a downward flexure of an arm rest and informs a user of the downward flexure on a display unit. By providing a partially color changing display or a blinking display on the display unit, the user is informed that a measurement posture is not good. The blood pressure measurement apparatus has an elbow rest with an arrangement that can easily prompt the user to be in a good posture for measurement.
US08753274B2
An operator-controllable medical monitoring system including at least one medical sensor that is adapted to monitor at least one patient characteristic, a plurality of medical monitors, each including a monitor wireless transceiver and a medical information display and a patient companion assembly including a patient companion assembly wireless transceiver and a medical monitor selector wirelessly operative to initially select one of the plurality of medical monitors and to provide a monitor selection indication which is visually sensible to the operator.
US08753273B1
Improved methods and systems for personal medical monitoring are disclosed. The monitoring yields status information pertaining to persons being monitored. Notifications, recommendations and/or actions can be initiated by examination or analysis of the status information. The status information can include health, position (location) and other information.
US08753271B1
A surgical access system including a tissue distraction assembly and a tissue refraction assembly, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.
US08753264B2
A seal is provided for effectively inhibiting the egress of fluids from the working channel of an endoscope when an elongate device having a region with a non-circular cross-sectional shape is disposed therein. The seal has a body portion with a proximal end adapted for insertion of the elongate device, a distal end adapted for connection to the proximal end of the endoscope, and a wall defining a lumen adapted to receive the elongate device and to provide access to the working channel of the endoscope. The seal includes a sealing element for sealing the region of the elongate device with a non-circular cross-sectional shape. The sealing element conforms to the profile of the non-circular region.
US08753255B2
Compositions, articles, and methods for treating and imaging vulnerable plaque and other inflamed regions in a patient rely on delivery of a conversion electron emitting source (CEES) to a body location. The CEES may be delivered by coupling to a substance which preferentially binds to vulnerable plaque or other inflammatory marker. Alternatively, the CEES can be delivered on a catheter, scaffold, or other device.
US08753252B2
An exercise apparatus includes a substantially flat, rigid platform for supporting a user during exercise. An inflatable tubular support having an upper portion with a first radial outside diameter, and a lower portion with a second radial outside diameter that is greater than the first radial outside diameter, is coupled to the platform by a fastener. The tubular support defines a central opening that communicates between the platform and a support surface. The platform includes a venting structure for releasing air from the central opening during use. The inflatable support includes an intermediate portion between the upper portion and the lower portion of the tubular support, the intermediate portion including a support feature to restrain the intermediate portion from radial expansion induced by an air pressure internal to the integral inflatable support.
US08753251B2
A jaw exerciser is provided. The jaw exerciser includes an elongated first portion having a first cross-sectional area, wherein the elongated first portion is configured to be inserted into the mouth, and includes an outer surface adapted to be engaged and clenched by the teeth. The jaw exerciser also includes an elongated second portion having a second cross-sectional area and an outer surface, wherein the elongated second portion is configured to remain outside the mouth when the first portion is inserted into the mouth. Furthermore, the jaw exerciser includes an intermediate portion having a third cross-sectional area. The intermediate portion joins the elongated first and second portions, and is configured to be grasped and encircled by the lips to thereby retain saliva inside the mouth.
US08753249B2
A control apparatus for an automatic transmission mechanism including a continuously variable transmission having a drive pulley, a driven pulley, and a belt extending around the two pulleys. When beginning of the start of a drive source for driving a vehicle has been detected, a first command oil pressure as a command value of a first control oil pressure supplied to a cylinder chamber of the drive pulley is set to a first predetermined oil pressure substantially equal to 0, and a second command oil pressure as a command value of a second control pressure supplied to a cylinder chamber of the driven pulley is set to a second predetermined oil pressure higher than the first predetermined oil pressure. When the detected second control oil pressure has reached a predetermined threshold value, it is determined that filling of the cylinder chamber of the driven pulley has been completed. A control for increasing the first command oil pressure is performed from a time point when completion of the filling of the cylinder chamber of the driven pulley has been determined.
US08753243B2
A turbine engine includes an epicyclic gear train that has a two-piece ring gear. Each portion of the ring gear includes radially outwardly extending flanges that are axially constrained to a turbo fan shaft by bolts secured circumferentially along the flanges. Knife edge seals are secured to the flanges to contain oil expelled through the ring gear into a gutter. The ring gear and turbo fan shaft can be rotationally balanced together.
US08753242B2
Providing a vehicular power transmitting system which includes a torque limiter device and which is configured to reduce deterioration of durability of a rotary member disposed between an engine and the torque limiter device. An inertia moment of a first rotary portion of a torque limiter device about its axis (first axis RC1) is smaller than an inertia moment of a second rotary portion about its axis (first axis RC1), so that an inertia moment of rotary members between an input shaft and the first rotary portion can be reduced as compared with that where the above-indicated inertia moment is larger than the inertia moment. Accordingly, the torque which transiently acts on a rotary member disposed between the engine and the torque limiter device, for instance, acts on the input shaft, during an operation of the torque limiter device, that is, during a slipping motion of the first rotary portion and the second rotary portion can be reduced, so that the deterioration of durability of the input shaft can be reduced.
US08753237B2
An alternator assembly for a motor vehicle is disclosed. The alternator assembly includes a rotor including a shaft. A torsion member is disposed inside a central cavity of the shaft. A pulley is connected to the torsion member to allow some decoupling between the pulley and the shaft.
US08753236B2
A segmented pulley transmission [20] is provided. A pulley assembly [36] is rotationally mounted on an axle [32]. The pulley assembly [36] includes a core pulley [45] having a first set of mating features on a peripheral surface thereof. A pulley segment set comprises a number of pulley segments [48] slidably mounted in the pulley assembly and arranged in a ring concentric with the core pulley [45]. The pulley segments [48] are individually actuatable out of the pulley assembly into an engaging position and into the pulley assembly into a non-engaging position. The pulley segments [48] have a second set of mating features [52] on an peripheral surface matching the first set of mating features. An endless drive member [47] has corresponding mating features on an inside surface for engaging the first and second sets of mating features of the core pulley [45] and the pulley segments [48] in an engaging position. Contact between the endless drive member [47] and a core pulley defines a contact zone [CZ]. An actuator [80] actuates the pulley segments [48] between the engaging and non-engaging positions when the pulley segments [48] are outside of the contact zone [CZ]. One of the pulley segments [48] in the pulley segment set is a key pulley segment [48a] that is positioned relative to the care pulley [45] such that when the key pulley segment [48a] is actuated to the engaging position and rotated into the contact zone [CZ], the corresponding mating features of the endless drive member [47] engage the first set of mating features of the core pulley [45] and the second set of mating features [52] of the key pulley segment [48a] without the introduction of significant slack or tension.
US08753233B2
The present invention provides for the first time a swing trainer having a sheath with a core end and a protective end, the core end of the sheath has a cover attached.
US08753227B1
A weight screw for a golf club head having one or more weight ports is disclosed herein. A set of weight screws is also disclosed herein, the set comprising at least one low-weight screw comprising multiple materials and at least one weight screw comprising a single material.
US08753226B2
A golf club head having a face component, a crown, and a composite sole or a composite body patch with one or more weight ports for receiving one or more weight inserts is disclosed herein. At least part of each of the weight ports is integrally formed in the composite sole or composite body patch, and each of the weight ports includes an upper edge, a lower edge, and a wall having a variable thickness and varying radius.
US08753225B1
A golf club having features that permit easy customization by consumers is disclosed herein. The golf club includes at least one weight port, at least one removable weight port insert, which may be a weight port ring or one or more weight port medallions, and at least one weight screw. The weight port of the golf club head preferably is non-circular and asymmetric.
US08753220B2
A set of progressive golf clubs with an elliptical pad construction on the back of the striking face that corresponds to a location, shape and size of a predetermined golfer's impact pattern for the lofts and lengths of each of the golf clubs in the set. The elliptical pad progressively changes in location, shape and size from the long irons, to the mid irons, to the short irons, and to the wedges, based on the location, shape and size of a predetermined golfer's impact pattern for each of the long irons, mid irons, short irons, and wedges.
US08753218B2
This golf course includes a fairway (11), tees (17), greens (1), holes (3) and bunkers (4), and other customary obstacles (6). As a particular feature, it has a special lighting arrangement, such that it also allows golf to be played during hours of darkness. To this end, at least the tees (17), the greens (1), the bunkers (4) and obstacles (6) are each equipped with a series of discrete or continuous light sources (12, 15, 18, 20, 36), preferably in the form of ground-installed LEDs or of OLEDs or LEDs. These lights extend along the edges of the objects in question and are installed flush with the ground. The holes (3) are illuminated internally by means of a light source, and the flagpoles (24) are designed as removable illuminating poles, such that the hole (3) remains lit even after removal of the flagpole. On a golf course equipped in this manner, the game of golf is played with an illuminating golf ball. The length of time it is possible to play on a golf course is extended substantially, and a highly attractive ambience is created on the course.
US08753213B1
The present disclosure describes an administration system which facilitates efficient setup, organization, and maintenance of tournaments, including league games. In particular, the administration system provides a user-friendly, intuitive and efficient-to-use interface for organizing tournaments and tournament brackets. The user interfaces and methods described provide tournament organizers and administrators with the ability to quickly and dynamically build custom tournament brackets of virtually any desired depth and configuration. The administration system, and in particular the tournament bracket management user interfaces, enable tournament administrators to focus on the task of building a custom tournament bracket structure quickly, while also automatically handling the minute logistics underlying the tournament such as when and where games are to be played.
US08753211B2
Various embodiments of the present invention provide a game system that enables a player to easily select an item to be used by a player character. The game system according to an embodiment of the present invention comprises a selection unit configured to select, from player game contents owned by a player, one or more game contents to be used by a player character of the player in a battle with an opponent character, based at least on an effective value calculated by the effective value calculating unit.