US09453133B2
The architectural compositions, such as paints and stains, include an additive comprising a plurality of latex particles added to an existing mixture of opacifying pigments and a film-forming binder as an admixture. Each latex particle is made from a latex polymer copolymerized with a polymerizable surfactant. The latex polymer is a non-film forming polymer at ambient temperatures.
US09453126B2
There is provided a novel dicyanatophenyl-based difunctional cyanate ester which is in a liquid form at ordinary temperature and can obtain a cured product having an excellent low thermal expansion rate. There is disclosed a cyanate ester compound represented by the following formula (I): (wherein R1 represents a hydrocarbon group having 2 to 20 carbon atoms).
US09453118B2
The present invention relates to a graphene-based hybrid polymer composite fiber and a method for manufacturing same, and more particularly, to a hybrid composite fiber including the graphene, a carbon nanotube, and a polymer, wherein the graphene and the carbon nanotube are combined by means of self-organization through hydrogen bonding, so as to be very tough and flexible, without involving stretching, and to a method for manufacturing the hybrid composite fiber.
US09453117B2
The present invention relates to phosphorous-containing triazine compounds. Polymers containing the phosphorous-containing triazine compounds also are provided. The polymers may include thermoplastic or thermoset polymers. The phosphorous-containing triazine compounds may be flame retardants.
US09453116B2
Composition embraces a fire retardant coating formulation that intumesces at a low temperature. The composition can be in a form of a paint, for instance, having as a primary fire retardant ingredient an ammonium phosphate and also having as a low-temperature intumescent agent an expandable graphite powder or flake. A temperature of intumescence can be substantially below 204.4° C. (400° F.) or thereabout, and it may have more than one temperature of intumescence. Such a composition can be made by contacting a fire retardant formulation, optionally with another active agent, with a low-temperature intumescencent agent under conditions sufficient to form the composition; it can be used by contacting it with a substrate, which may be otherwise flammable. Another aspect is the composition or its residue in combination with the substrate.
US09453113B2
Polybranched organic/inorganic hybrid polymer and method for its manufacture. The hybrid polymer has the form of an inorganic core carrying organic branches. The core is first prepared by controlled hydrolysis and condensation of a silane with a structure: X—B—Si(—Y)3 in which X=NR1R2, while R1, R2 are chosen among hydrogen, alkyl and aryl, or R1, R2 are chosen among condensation products, addition products of one or more type of chemical substances such as acids, alcohols, phenols, amines, aldehydes or epoxides. B is a linkage group chosen among alkylene and arylene which may include oxygen, nitrogen, sulphur, phosphorous, silicon and boron. Y is chosen among hydrolyzable residues such as alkoxy, carboxyl, and halogen. The organic branches are developed by substituting N—H hydrogen atoms in the X—B group by reactions that are typical for primary and secondary amines, and/or by adding an acid that causes an addition to the N atoms of the X—B group in the core. Specific uses of the hybrid polymers are also indicated.
US09453096B2
Disclosed is a method for producing a plastisol acrylic polymer which can have a satisfactory adhesion property even when the heating time is short and the heating temperature is low, and which has excellent storage stability. The method comprises (1) a step of polymerizing an acrylic monomer mixture (a) to produce a polymer (A) and (2) a step of polymerizing an acrylic monomer mixture (b) in a dispersion containing the polymer (A), wherein a monomer having a hydroxy group is contained in the acrylic monomer mixture (a), a monomer having an acetoacetyl group or a block isocyanate group is contained in the acrylic monomer mixture (b), and the dissolution parameter (SA) for the polymer (A) and the dissolution parameter (SB) for a polymer (B) produced by the polymerization of the acrylic monomer mixture (b) are different from each other.
US09453094B2
The present invention provides a resin composition containing (A) an ethylene-vinyl alcohol copolymer and (B) an unsaturated aldehyde (B), in which the content of the unsaturated aldehyde (B) with respect to the resin composition containing the ethylene-vinyl alcohol copolymer is 0.01 ppm or more and 100 ppm or less. The unsaturated aldehyde (B) is preferably crotonaldehyde, 2,4-hexadienal, 2,4,6-octatrienal or a combination thereof. In addition, it is preferred that the resin composition further contains a boron compound, and the content of the boron compound is 100 ppm or more and 5,000 ppm or less. Also, it is preferred that the resin composition further contains a conjugated polyene compound, and the content of the conjugated polyene compound is 0.01 ppm or more and 1,000 ppm or less.
US09453090B2
Process for producing a thermoplastic polymer foam article includes preparing an expandable polymeric formulation comprising a thermoplastic polymer and a blowing agent blend, forming the formulation into an expandable bead, and expanding the expandable bead to form a thermoplastic polymer foam article. The blowing agent blend includes methyl formate, hydrocarbon, and either carbon dioxide or 1,1,1,2-tetrafluoroethane (HFC-134a). The blowing agent blend has a higher effective volatility than that of methyl formate alone. A thermoplastic polymer foam article prepared by a process is also provided.
US09453082B2
There is provided a composition comprising a polysaccharide obtainable from the microalgae, Prasinococcus capsulatus and strains related to P. capsulatus for use prophylactically and/or therapeutically in the treatment of disorders of the immune system, for example in psoriasis and dermatological conditions, internal immune system disorders, in particular gut inflammatory conditions and respiratory conditions. Further, there is provided derivatives of a polysaccharide obtainable from the microalgae, Prasinococcus capsulatus or an algal strain related to P. capsulatus and the use of such derivatives prophylactically and/or therapeutically in the treatment of disorders of the immune system.
US09453081B2
A reaction product mixture is obtained from a reaction of (a) a cellulose ether with (b) an aliphatic monocarboxylic acid anhydride or with a di- or tricarboxylic acid anhydride or with a combination of an aliphatic monocarboxylic acid anhydride and a di- or tricarboxylic acid anhydride in the presence of (c) an aliphatic carboxylic acid. A process for precipitating an esterified cellulose ether from this reaction product mixture comprises the step of contacting the reaction product mixture with water and subjecting the combination of water and the reaction product mixture to a shear rate of at least 800 s−1. The precipitated esterified cellulose ether can be recovered as a non-tacky product.
US09453080B2
This disclosure relates to antagonistic dual receptor antigen-binding proteins, e.g. antibodies and methods of using the dual receptor antibodies for treatment of pathological diseases. The dual receptor antibodies may comprise an antibody to ActRII receptors and may be used to treat pathological condition. The pathological conditions can comprise muscle wasting diseases or any disease that requires stimulation of muscle growth.
US09453078B2
The present disclosure provides modified antibodies which contain an antibody or antibody fragment (AB) modified with a masking moiety (MM). Such modified antibodies can be further coupled to a cleavable moiety (CM), resulting in activatable antibodies (AAs), wherein the CM is capable of being cleaved, reduced, photolyzed, or otherwise modified. AAs can exhibit an activatable conformation such that the AB is more accessible to a target after, for example, removal of the MM by cleavage, reduction, or photolysis of the CM in the presence of an agent capable of cleaving, reducing, or photolyzing the CM. The disclosure further provides methods of making and using such modified antibodies and activatable antibodies.
US09453077B2
The present invention provides isolated human monoclonal antibodies that bind to IFNAR-1 and that are capable of inhibiting the biological activity of Type I interferons. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of the invention are also provided. The invention also provides methods for inhibiting Type I interferon-mediated disorders using the antibodies of the invention, including methods for treating autoimmune disorders, transplant rejection or Graft Versus Host Disease using the antibodies of the invention.
US09453071B2
The invention relates to binding partners of the placental growth factor (or placenta growth factor, PlGF), especially antibodies directed against the placental growth factor, and production and use thereof.
US09453070B2
The inventors discovered that the adhesion molecule CAR, known to be localized in intracellular adhesion sites, functioned as an adhesion molecule for activated lymphocytes. Further, the inventors identified CARL, a novel CAR ligand expressed in lymphocytes, and clarified that the ligand was expressed selectively in Th1 cells. In addition, they found that anti-CAR antibodies could inhibit the adhesion of activated lymphocytes to CAR molecules. Thus, the present invention provides methods for detecting Th1 cells using CAR or anti-CARL antibodies, and methods of screening for inhibitors suppressing the adhesion of Th1 cells using the binding between CAR and CARL as an index. Furthermore, the present invention relates to methods of screening for inhibitors of the binding between CAR and CARL, antibodies that inhibit the binding between CAR and CARL, and therapeutic compositions comprising these antibodies. These are expected to be useful in diagnosing diseases, such as inflammation, in which infiltration of Th1 cells is involved, and in providing pharmaceutical agents for alleviating such diseases.
US09453045B2
A process of purifying the Growth Factor Protein G-CSF (Granulocyte Colony Stimulating Factor) in a purification sequence employing chromatography, comprising binding the G-CSF to Capto MMC™, which is a multimodal resin that comprises a negatively charged 2-(benzoylamino) butanoic acid ligand, at a pH from 4 to 6.2; and eluting the G-CSF at a pH greater than 6.3.
US09453043B2
The present invention provides nucleosides of formula (1) and oligonucleotides comprising at least one nucleoside of formula (2): Another aspect of the invention relates to a method of inhibiting the expression of a gene in cell, the method comprising (a) contacting an oligonucleotide of the invention with the cell; and (b) maintaining the cell from step (a) for a time sufficient to obtain degradation of the mRNA of the target gene.
US09453039B2
The present invention relates to physical crystal structures of a compound of the formula I: wherein R1, R2, R2a, R3 and R4 are as defined herein, especially pharmaceutical compositions containing structures of compound I or II, processes for preparing same, intermediates used in preparing same, and methods of treating diseases such as diabetes using such structures.
US09453034B2
In its many embodiments, the present invention provides certain C2-azaspirosubstituted iminothiazine dioxide compounds. The novel compounds of the invention are useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including for the possible treatment of Alzheimer's disease, are also disclosed.
US09453032B2
Broad spectrum beta-lactamase inhibitors. Certain inhibitors also exhibit potent antibiotic activity in addition to beta-lactamase inhibition. Compounds of the invention are designed such that on cleavage of the beta-lactam ring reactive moieties are generated which can inactivate beta-lactamase. Also provided are methods of making beta-lactamase inhibitors and beta-lactam antibiotics exhibiting such inhibition. Additionally provided are pharmaceutical compositions for treatment or prevention of bacterial infections and methods of treatment of such infections.
US09453029B2
The present invention provides compounds of Formula (I): or a stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of fXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.
US09453017B2
Disclosed are methods of treating viral infections comprising, in one aspect, administering compounds that are phospholipase D inhibitors. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. In accordance with the purpose(s) of the invention, as embodied and broadly described herein, the invention, in one aspect, relates to antiviral therapies. For example, compounds having Phospholipase D activity (e.g., isoform selective Phospholipase D inhibitors) can be useful in antiviral therapies (e.g., influenza treatments).
US09453016B2
The invention relates to compositions and methods (with regard to animals and humans) for utilizing an extract and/or one or more natural spiro triterpenoids and derivatives thereof alone or as a supplement. Certain materials utilized are from the blazeispirol family, obtainable from Agaricus species. Treatments include the prophylactic and/or therapeutic treatment of a disease, disorder or condition that responds to the modulation of Liver X receptor, as well as corresponding methods of treatment, the manufacture of a pharmaceutical and nutraceutical formulation for said treatment. The invention also relates to the use of the extract and compound(s) in the treatment or in the preparation of a medicament (e.g. a nutraceutical) for the prophylactic and/or therapeutic treatments, as well as their preparation. It also relates to pharmaceutical or nutraceutical formulations described herein which are useful in prophylactic and therapeutic treatments. They can also be used for non-therapeutic, e.g. cosmetic, purposes.
US09453006B2
Means for improving the solubility of luliconazole is provided. A crystal of luliconazole represented by the following formula is provided, wherein the crystal has such a crystal habit that (011) plane is a specific crystal growth plane. The crystal is characterized in that I(011) with respect to a sum total of I(001), I(100), I(10-1), I(011), I(110), I(11-1), I(10-2), I(11-2), I(020), I(021), I(20-2), I(121), I(013), I(11-3), and I(221) is not less than 25%, provided that integrated intensities of diffraction peaks, which correspond to the (001), (100), (10-1), (011), (110), (11-1), (10-2), (11-2), (020), (021), (20-2), (121), (013), (11-3), and (221) planes, are designated as I(001), I(100), I(10-1), I(011), I(110), I(11-1), I(10-2), I(11-2), I(020), I(021), I(20-2), I(121), I(013), I(11-3), and I(221) respectively in relation to the diffraction peaks detected in a range of 2θ=5 to 35° in a powder X-ray diffractometry using CuKα radiation.
US09453000B2
Disclosed is a compound represented by the formula (I): or a pharmacologically acceptable salt thereof, which is effective as a therapeutic or prophylactic agent for a disease induced by Aβ, wherein Ar1 represents an imidazolyl group which may be substituted with a C1-6 alkyl group, or the like; Ar2 represents a phenyl group which may be substituted with a C1-6 alkoxy group, or the like; X1 represents a double bond, or the like; and Het represents a triazolyl group or the like which may be substituted with a C1-6 alkyl group or the like, or the like.
US09452999B2
The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.
US09452992B2
The present invention relates to compositions and methods for the treatment of infection by enveloped viruses, such as Ebola and Lassa fever viruses.
US09452991B2
HPV inhibitors with formula (I) where G1 represents a hydrocarbonated bond or chain possibly substituted by one or two alkyl groups, G2 represents a group (see formula Ia+Ib) or R represents a hydrogen, an alkyl, halogenoalkyl, or a prodrug radical such as carbamate, acetyl or dialkylaminomethy, G represents a bond or a hydrocarbonated chain possibly substituted by one or two alkyls, W represents an oxygen or sulphur, R1 and R2 each represent a group chosen from among hydrogen, halogen, hydroxyl, thio, alkoxy, halogenoalkoxy, alkylthis, halogenoalkylthio, amino, monoalkylamino, dialkylamino, cycloalkyl, alkyl or halogenoalkyl, R3 represents an acid or a prodrug radical of the acid function or a bioisotere of the acid function, A represents an aryl, cycloalkyl, cycloalkenyl or a heterocycle with 6 chains, each possibly substituted, and pharmaceutically acceptable salts.
US09452977B2
A compound having a hypoglycemic effect is provided. The compound and a pharmaceutically acceptable salt thereof are useful for the treatment or prevention of diabetes, obesity, and the like. The compound is represented by the general formula (1): (wherein R1 and R2 are each independently a hydrogen atom, a halogen atom, an amino group, a hydroxyl group, a hydroxyamino group, a nitro group, a cyano group, a sulfamoyl group, a C1 to C6 alkyl group, a C1 to C6 alkoxy group, a C1 to C6 alkylsulfanyl group, a C1 to C6 alkylsulfinyl group, a C1 to C6 alkylsulfonyl group, or a C1 to C6 alkoxy-C1 to C6 alkylsulfonyl group, and A is a substituted or unsubstituted heteroaryl group).
US09452953B2
Compositions, methods and systems involving nitrate compounds are disclosed and described. A method of dissolving a nitrate compound having an additive can comprise dissolving the nitrate compound to form an aqueous nitrate solution and adding a surfactant to the aqueous nitrate solution, where the surfactant disperses the additive.
US09452949B2
The present invention relates to a composite material, particularly a composite material for ceramic tiles, stone cladding, surface tops (e.g. worktops), and the like. The composite materials are typically derived from waste products. The composite materials of the present invention are formed from a glass component and a non-glass mineral component (e.g. ceramics and/or glaze). Generally the composite materials do not require any binders (especially synthetic binders) to hold the materials together. Therefore, the composite materials and products made therefrom are typically recyclable.
US09452945B2
An apparatus for making a glass sheet using overflow fusion down-draw process comprising an inlet assembly having an elliptic cylindrical section coupled to a transition section which is, in turn, coupled to an open end of an open channel of an isopipe, and an overflow fusion down-draw process for making glass sheet. The glass melt flow has a high surface velocity profile conducive to the formation of a glass ribbon over the surface of the weirs and the wedge side surfaces with the desired mass distribution.
US09452937B2
This disclosure is directed to a method for directly preparing pure phase aluminosilicate molecular sieves having the IFR framework type using a colloidal aluminosilicate composition in the presence of N-benzyl-4-aza-1-azoniabicyclo[2.2.2]octane cations as a structure directing agent.
US09452934B2
Ultra-large graphene oxide (UL-GO) sheets are formed using a Langmuir-Blodgett (LB) thin film process. Sulfuric acid and nitric acid are applied to interlayers of natural graphite flake to form graphite intercalation compound (GIC) powders. The GIC powders are expanded at a high temperature, and intercalating agents are used to further oxidize the expanded GIC powders by to exfoliating the EG into monolayer graphene oxide (GO) sheets. The GO is sequentially centrifuged and UL-GO sheets are collected. An LB thin film is prepared from the collected sheets and the thin films are reduced and chemically doped.
US09452933B2
A process for preparing a mesoporous metal oxide, i.e., transition metal oxide, Lanthanide metal oxide, a post-transition metal oxide and metalloid oxide. The process comprises providing a micellar solution comprising a metal precursor, an interface modifier, a hydrotropic ion precursor, and a surfactant; and heating the micellar solution at a temperature and for a period of time sufficient to form the mesoporous metal oxide. A mesoporous metal oxide prepared by the above process. A method of controlling nano-sized wall crystallinity and mesoporosity in mesoporous metal oxides. The method comprises providing a micellar solution comprising a metal precursor, an interface modifier, a hydrotropic ion precursor, and a surfactant; and heating the micellar solution at a temperature and for a period of time sufficient to control nano-sized wall crystallinity and mesoporosity in the mesoporous metal oxides. Mesoporous metal oxides and a method of tuning structural properties of mesoporous metal oxides.
US09452929B2
Provided are a photoelectrode including a zinc oxide hemisphere, a method of fabricating the same, and a dye-sensitized solar cell using the same. The photoelectrode includes a conductive substrate, a zinc oxide hemisphere disposed on the conductive substrate, and a porous metal oxide layer covering the zinc oxide hemisphere. Light scattering effects of photoelectrodes can be increased, and recombination losses of electrons can be minimized to improve photovoltaic properties.
US09452927B2
A method and device for the rapid detection of biomolecules (320) diffusing in a nanometer-confined slit (204) is claimed. In particular, the present invention relates to a novel concept of fluidic side apertures (205) that facilitates the filling of the device, the surface coating with biomolecules and that measures the affinity between fluorescently labeled biomolecules in aqueous solution with other biomolecules immobilized on surfaces.
US09452923B2
A method for manufacturing a micromechanical system includes creating a sacrificial layer at a substrate surface. A structural material is deposited at a sacrificial layer surface and at a support structure for later supporting the structural material. At least one hole is created in the structural material extending from an exposed surface of the structural material to the surface of the sacrificial layer. The at least one hole leads to a margin region of the sacrificial layer. The sacrificial layer is removed using a removal process through the at least one hole, to obtain a cavity between the surface of the substrate and the structural material. The method also includes filling the at least one hole and a portion of the cavity beneath the at least one hole close to the cavity. A corresponding micromechanical system and a microelectromechanical transducer are also described.
US09452914B2
Load manipulator comprising a boom arm (1) and a return arm (3) parallel to each other, a loading bar (2) and a counterbar (4) so as to form a deformable parallelogram, an approximately horizontal pivot axis on which one of the arms of the parallelogram is articulated, and balancing means (8) applying a force at an compensation application point (C) to compensate for the force due to the load, said point being a point on the return arm (3) and a point on the counterbar such that it is always in line with point (M) on the loading bar at which the force due to the load is applied and the rotation axis, in which the balancing means (8) comprise a first counterweight (10) and a second counterweight (12) and a jack to compensate for the value of the force due to the load, the first counterweight (10) and the jack applying a force onto the compensation application point (C) and the second counterweight (12) applying a force on the boom arm (1).
US09452910B2
A lanyard assembly for lifting a rescue stretcher, includes a lifting gear with a lower fastening arrangement to be fixed at different fastening points of the stretcher, and a rope assembly to connect the lifting gear with a lifting device, wherein the rope assembly includes a set of rope sections, each rope section having a fixed length and a first end being connectable to the lifting device and an opposite second end being connectable to the first end of any other rope section or to the lifting gear.
US09452908B1
An apparatus and method for dispensing wire or cable from a reel assembly. In one embodiment, the apparatus comprises an inner flange assembly and an outer flange assembly. The inner flange assembly is capable of freely rotating relative to the outer flange assembly for dispensing wire from any surface. In another embodiment, the apparatus includes an inner flange assembly, an outer flange assembly, and an external bay. The inner flange assembly is capable of freely rotating relative to the outer flange assembly and the external bay. The external bay is capable of freely rotation relative to the outer flange assembly and the inner flange assembly. In another embodiment, wire is dispensed from a reel assembly comprising an inner flange assembly and an outer flange assembly. In yet another embodiment, wire is dispensed from a reel assembly comprising an inner flange assembly, an outer flange assembly, and an external bay.
US09452896B2
A conveyor system with a pop-up transfer assembly for transferring articles off the end of conveyor belt having protrusions extending above the belt's outer conveying surface. The transfer assembly is cantilevered over the reversing path of the conveyor belt from a pivot. When a protrusion from the belt hits the transfer assembly, the transfer assembly pivots away from the belt about the pivot. When the protrusion is clear, the transfer assembly drops, by gravity, back to its home position proximate the belt. A bilateral transfer assembly is cantilevered in opposite directions to transfer articles off the end of one conveyor belt onto another conveyor belt that may or may not have protrusions.
US09452894B2
The invention relates to a storage and order-picking system (1) for the fully-automated picking of articles that are stored in storage loading aids (2) and are picked according to an order, which includes an article store, a first conveyor system that conveys storage loading aids leaving the article store to a picking station that is operated unmanned, a fully-automated robotic gripping unit on said picking station, which removes articles to be picked from said storage loading aids and deposits them in accordance with the order, the articles deposited according to an order, particularly in an order loading aid, subsequently being conveyed away by means of a second conveyor system, an image identification device for determining possible gripping points for the gripping unit in order to grip articles from the storage loading aids, wherein the image identification device comprises at least one and preferably at least two cameras in the region of the robotic gripping unit (9) and, if at least two cameras are provided, the capturing directions thereof are aligned into the storage loading aid located in the gripping region of the gripping unit, while being coordinated and in particular inclined toward each other.
US09452892B2
A conveyor belt comprising (1) an elastomeric body having a load carrying surface and a parallel pulley engaging surface; (2) a reinforcement ply disposed within the elastomeric body; (3) a rip detection sensor in the form of a microcoil sensor wire which is configured in an endless loop, wherein the microcoil sensor wire is comprised of an elastomeric core having an electrically conductive wire spirally wrapped around the elastomeric core.
US09452883B1
Inventory holders in an inventory system can be moved among differing storage positions. The moves can be performed by mobile drive units not otherwise transporting inventory holders directly to or from inventory stations. A free mobile drive unit can move an inventory holder not likely to be useful soon at any nearby station from a storage position near the station to a position farther away from the station. A mobile drive unit can move an inventory holder likely to be useful soon from a storage position farther away from one or more stations to a storage position nearby one or more stations.
US09452881B2
A cargo transportation locker, the locker comprising: a floor; a first corner post in communication with the floor; a second corner post in communication with the floor; a third corner post in communication with the floor; a fourth corner post in communication with the floor; a first door in rotatable communication with the first corner post, the first door comprising: a first angled door member located in an upper corner of the first door adjacent the first post, where the first angled door member makes an angle with the top side of the first door of less than 90°, and makes an angle of less than 90° with the hinged side of the first door; a second angled door member located in a lower corner of the first door adjacent the first post, where the first angled door member makes an angle with the bottom side of the first door of less than 90°, and makes an angle of less than 90° with the hinged side of the first door; a second door in rotatable communication with the second corner post; the second door comprising: a third angled door member located in an upper corner of the second door adjacent the second post, where the third angled door member makes an angle with the top side of the second door of less than 90°, and makes an angle of less than 90° with the hinged side of the second door; a fourth angled door member located in a lower corner of the second door adjacent the second post, where the fourth angled door member makes an angle with the bottom side of the second door of less than 90°, and makes an angle of less than 90° with the hinged side of the second door. A cargo transportation locker, the locker comprising: a floor; a first corner post in communication with the floor; a second corner post in communication with the floor; a third corner post in communication with the floor; a fourth corner post in communication with the floor; a first door in rotatable communication with the first corner post, the first door comprising: a first angled door member located in an upper corner of the first door adjacent the first post, where the first angled door member makes an angle with the top side of the first door of less than 90°, and makes an angle of less than 90° with the hinged side of the first door; a second angled door member located in a lower corner of the first door adjacent the first post, where the first angled door member makes an angle with the bottom side of the first door of less than 90°, and makes an angle of less than 90° with the hinged side of the first door; a first door handle; the first door handle comprising: a slideable member configured to slide from the first door to the second door, and when slid into the second door, the first and second doors are locked in a closed orientation; a first slideable member hole, located in the slideable member, and when first slideable member hole is padlocked, the first and second doors are locked in a closed orientation; a second slideable member hole, located in the slideable member, and when second slideable member hole is padlocked, the slideable member does not restrict the second door from opening and closing. a second door in rotatable communication with the second corner post; the second door comprising: a third angled door member located in an upper corner of the second door adjacent the second post, where the third angled door member makes an angle with the top side of the second door of less than 90°, and makes an angle of less than 90° with the hinged side of the second door; a fourth angled door member located in a lower corner of the second door adjacent the second post, where the fourth angled door member makes an angle with the bottom side of the second door of less than 90°, and makes an angle of less than 90° with the hinged side of the second door; a second door handle, the second door handle comprising: an upper spring loaded sliding member; at least one spring in communication with the supper spring loaded sliding member; a lower spring loaded sliding member in communication with the at least one spring; an upper locking rod in communication with the upper spring loaded member; a lower locking rod in communication with the lower spring loaded member; a first top support member in communication with the first corner post and the second corner post, the first top support member having a upper rod hole in its underside; a first floor support member located beneath the floor and in communication with the first corner post and second corner post, the first floor support member having a lower rod hole in its upper side; and where when the upper spring loaded sliding member and lower spring loaded sliding member are fully spread apart, the upper locking rod extends through the upper rod hole, and the lower locking rod extends through the lower rod hole thereby locking the second door to the locker, and when the upper spring loaded sliding member and lower spring loaded sliding member are squeezed together, the upper locking rod retracts from the upper rod hole and the lower locking rod retracts from the lower rod hole, thereby unlocking the second door from the locker.
US09452874B2
The carton of this invention is capable of carrying the plurality of containers stacked upon their ends in two tiers with a unique dispenser that permits the dispensing of containers on their sides. The dispenser is formed in a top side wall and extends into the end wall with most of the end wall being torn open but leaving a portion near the bottom side wall to prevent the bottom layer of containers from rolling out. Angled projections in the dispensing end of the carton near the top panel and bottom panel prevent the top layer of containers from rolling out. A divider may be inserted between the two tiers of containers to facilitate loading the carton and preventing the containers from accidentally rolling out when the dispenser is open.
US09452871B1
A container lid assembly is a lid unit for covering an upper-end opening of a container. The lid unit includes a lower connecting member peripherally mounted with a ring, an intermediate covering member, and an upper connecting member stacked in order. When the lid unit covers the container's opening and the upper connecting member is rotated manually, the lower connecting member is driven to move upward so that the ring at the periphery is pushed outward by the lower end of the intermediate covering member and closes the container's opening even more tightly, thereby providing desired sealing for the container.
US09452866B2
The present invention discloses a cup support and a dispensing device that uses a cup support. The cup support is adapted to hold at least cups of two different diameters and sizes. The cup support and the dispensing device are adapted to detect the diameter and size of the cup, and enable that when a diluent jet is injected into the cup, the jet is oriented to impact onto a predetermined position on a sidewall of the cup. The orientation of the jet achieves an effective dissolution of food ingredient in the cup by the injected diluent. The dispensing device is designed to move the cup support in a horizontal and vertical direction, to rotate the cup support. The cup support is not directly actuated, but is fitted into movable and rotatable holding means, from which it can be easily dismantled to be cleaned. The cup support comprises a plug element comprising one protusion. The dispensing device comprises a motor for vertically moving the cup support or the injection means.
US09452861B2
A blank of sheet material for forming a polygonal container is provided. The blank includes a bottom panel, two opposing side panels, and two opposing end panels. Each side panel extends from a side edge of the bottom panel, and each end panel extends from an end edge of the bottom panel. Each end panel includes at least one major stacking extension extending from a top edge thereof. The blank further includes a reinforcing panel assembly extending from a first side edge of a first end panel of the two end panels. The reinforcing panel assembly includes an inner end panel having a minor stacking extension extending from a top edge thereof. The minor stacking extension is configured to align with a respective major stacking extension to form a stacking tab.
US09452860B2
The present invention relates to a ventilation board, an insulating board, a ventilation system, and articles and architectural applications comprising said ventilation board and a method of manufacturing the ventilation board. The said ventilation board comprises a layer (11) provided with a first aperture (5); an adjacent layer provided (13) with a second aperture (7), the first and second apertures being located relative to each other such that they are non-aligned and are substantially without overlap; and a passageway (9) interconnecting the first and second apertures thereby permitting the passage of fluid therebetween. Therefore, the carton comprising said ventilation board when used for fast food packaging provides sufficient ventilation of the carton so that water condensed from food vapors does not run on to the food in the carton, and sufficient insulation so that the food in the carton is kept warm.
US09452846B2
A method of removing water (7) from a fuel tank (2) using a water scavenging line (4) which has an inlet (6) immersed in the water and an outlet (5) coupled to a water tank (3). The method comprises filling the fuel tank with fuel (30) whereby the fuel exerts hydrostatic pressure on the water, the hydrostatic pressure driving the water up the water scavengingline against the force of gravity and into the water tank. The use of hydrostatic pressure provides an automatic and relatively simple method of extracting the water from the bottom of the fuel tank. The water tank enables the extracted water to be stored for disposal at a later time, typically by feeding the water into an engine.
US09452840B2
One example of the present disclosure relates to a monolithic part including an exterior wall and a first cavity. The first cavity includes a first aperture in communication with the exterior wall and a first inner surface defining a first shape. The first shape prevents extraction from the first cavity, via the first aperture, of a first virtual object having the first shape.
US09452833B2
A drainage mast able to drain effectively the liquid contained in the compartment of an aircraft when the pressure within the compartment is lower than the outside pressure without using any pressure control active device and without causing any significant perturbation to the aerodynamic behavior of the aircraft. The drainage mast is configured with a cross section area decreasing from its entry section to the compartment to its outlet section and is disposed at an acute angle α relative to the compartment in the airflow direction. The entry and outlet sections have two perpendicular symmetry axes of different length, the entry section is arranged with its longer axis of symmetry substantially parallel to the airflow direction. The drainage mast has a symmetrical configuration with respect to a plane substantially perpendicular to the fuselage envelope passing through the longer axis of symmetry of the entry section.
US09452832B2
The invention relates to compensation for the torque which is produced by the main rotor (110) of a helicopter (100). The apparatus according to the invention for torque compensation is intended for a helicopter whose main rotor rotates about a rotation axis (RH) during operation and thus produces a torque, which acts on the fuselage (120) of the helicopter and would cause it to rotate. The apparatus comprises a lateral flow fan (200) having a housing (210) and having a rotor (220) which is mounted in the housing, wherein the lateral flow fan is arranged on the tail boom (130) of the helicopter such that it produces a thrust effect (F) during operation which compensates for the torque of the main rotor.
US09452831B2
An individual blade control system (IBCS) for a rotor system having a rotor hub is provided including a plurality of blade cuffs mounted to the rotor hub. Each blade cuff is configured to receive a rotor blade and rotate about a blade axis. A plurality of electrical actuators is mounted to the rotor hub adjacent at least one of the plurality of blade cuffs. Each electrical actuator is configured to rotate about an actuator axis. The plurality of blade axes and the plurality of actuator axes are arranged in a plane. Each electrical actuator is coupled to an adjacent blade cuff such that rotation of one of the plurality of electrical actuators causes a proportional rotation of one of the blade cuffs.
US09452827B2
The present disclosure includes landing gear components, such as an outer cylinder of a shock strut assembly. The outer cylinder includes one or more structural attachment pins configured to engage with other components of the landing gear including pintle frames, drag braces, and torque links. The pins include a cobalt alloy mated to a receptacle having a cobalt-containing coating on an inner surface, which eliminates the need for a bushing between the pin and the receptacle of the corresponding landing gear component.
US09452818B2
An aircraft comprising a wing box and a fuselage provided with a connecting device configured to be connected to the wing box and to transmit thereto stresses undergone by the fuselage during maneuvers of the aircraft are provided. The connecting device is formed by a keel beam and a keel beam panel connected to the beam via a connecting portion of the beam, that is moreover provided with a main portion extending in a first, generally longitudinal direction and a transfer portion extending in a second direction different from the first direction and configured to be connected to the box. The main, transfer and connecting portions are configured to direct a major part of the stresses received by the beam in the second direction and transmit said major part of the stresses to the box by compression.
US09452817B1
An aircraft for carrying passengers and/or cargo has first, second and third cabins arranged in a split level floor configuration within a fuselage. The cabin floors are connected by stairs, elevators or escalators. Two of the cabins are stacked above a reduced height lower hold which acts as an energy absorbing crush zone in the event of a crash.
US09452816B2
A system for airship hull reinforcement and in-situ repair includes a sensor for detecting a leak in the airship hull of a lighter-than-air airship and a repair mechanism inside lighter-than-air airship for dispensing repair material to seal the leak. A durable airship hull includes an inner gas barrier, an outer gas barrier, and a microlattice layer sandwiched between the inner gas barrier and the outer gas barrier.
US09452814B2
Embodiments provide for safely and reliably operating a generator in a submersible environment utilizing an autonomous control system. One embodiment is a power generation system that includes a generator, a water-tight enclosure surrounding the generator, an intake valve, an exhaust valve, and a controller. The intake valve couples an air intake on the generator to an outside surface of the enclosure. The exhaust valve couples an exhaust port on the generator to the outside surface. If the controller determines that the enclosure will submerge, then the controller stops the generator and closes the intake valve and the exhaust valve. After detecting that the enclosure has surfaced, the controller opens the intake valve, opens the exhaust valve, and starts the generator.
US09452806B2
At least a portion of a tie rod of a steering force transmitting mechanism overlaps with a portion of a first support member or a second support member when viewed from a front of a vehicle in a fully-tilted condition in which the vehicle body frame is fully tilted in the left-right direction. At least a portion of the tie rod is disposed below a second cross member, above a first front wheel and a second front wheel, behind a front end of the first front wheel and a front end of the second front wheel, and ahead of a first axis of a first side member and a second axis of a second side member when viewed from the left or right of the vehicle when the vehicle body frame is in an upright state.
US09452798B2
A bicycle seatpost assembly comprises a first cylinder, a second cylinder, and a positioning structure. The second cylinder is configured to be telescopically received in the first cylinder. The positioning structure is configured to relatively position the first cylinder and the second cylinder. The positioning structure includes a receiving member, a first seal member, and a movable member. The first seal member is configured to provide a first gate of a first passageway together with the receiving member. The first seal member includes a spherical surface contactable with the receiving member to close the first gate. The movable member is configured to move the first seal member relative to the receiving member to open the first gate.
US09452789B2
A peripheral structure of a front hood of a vehicle comprises an instrument panel arranged in a front part of a riding space and includes a first surface facing the riding space and a second surface extending diagonally forwardly and downwardly from an upper end of the first surface, and an openable and closable or detachable front hood extending forwardly of the second surface and covering from above a storage compartment which is arranged in front of the riding space and between a pair of left and right front wheels. The instrument panel has an extension section being located along the second surface and extending diagonally forwardly and downwardly under a rear end of the front hood. A step section is provided at a front end portion of the extension section and projects upwardly from an upper surface which is located in the rear of the front and portion.
US09452788B2
Provided is a top part structure of a vehicle body provided with: a roof side rail extending in a front-rear direction on a side part of the vehicle body, the roof side rail being formed by a rail inner, a rail outer joined to a vehicle outer side of the rail inner to form a cross-section, and a rail stiffener sandwiched between the rail inner and the rail outer to partition the closed cross-section; and a pillar extending downward from the roof side rail, the top part structure including: a bulkhead joined, at an intersection portion between the pillar and the roof side rail, to the rail stiffener, fastened by a bolt to the rail inner, and disposed such as to partition the closed cross-section between the rail inner and the rail stiffener.
US09452782B1
A replacement tailgate for the purpose of elongating the pickup truck may be installed on a truck bed wherein the replacement tailgate can be unfolded in order to elongate a length of the truck bed. The replacement tailgate may have front and rear shells that are used to support objects placed in the truck bed as well as act as the new tailgate when the truck bed length is elongated. Various panels may be unfolded in order to trap objects within the truck bed when the replacement tailgate is unfolded in order to elongate the truck bed length.
US09452779B2
A power steering system includes a first steering device which controls the steering of the first wheels of the vehicle according to a first steering angle α1 and includes a first actuator capable of providing a steering assistance effort, a second steering device including a second actuator controlled by a controller as a function of a parameter related to the steering wheel movement, and controlling the steering of the second wheels, according to a second steering angle α2. In normal operation of the power steering system, α2 is set according to a first rule depending on the first steering angle α1. In case the steering wheel torque is greater than a predetermined threshold, the second steering device is operated in a forced mode by setting the second steering angle according to a rule depending on the first steering angle and taking into account at least one different or additional data, in order to cause an offset-oversteering of the second wheel.
US09452777B2
A power steering device is provided with a device body and a hollow motor. The device body has a steering system in which a piston is disposed on an output shaft via a ball screw mechanism so that a steering (rotational) torque is transmitted from an input shaft to the output shaft and converted to rotation of a sector shaft by axial movement of the piston for steering of steerable wheels. The hollow motor is connected to the outer circumference of the input shaft and driven by energization control based on driving support information from a vehicle-mounted camera and the like. A key and a key groove are provided on the outer circumference of the input shaft and the inner circumference of a rotor of the hollow motor, respectively, so as to constitute a key connection between the input shaft and the hollow motor.
US09452774B2
A compensation control apparatus of motor driven power steering may include: a torque sensor for measuring a driver's column torque inputted to a steering wheel; and a controller for generating an assist torque based on the column torque measured through the torque sensor, compensating for a phase margin in a low-frequency band for the generated assist torque, detecting a resonance frequency to attenuate resonance, and outputting a final assist torque.
US09452767B2
A cart transportation apparatus can be used to transport carts from one location to another. Utilizing the cart transportation apparatus can reduce damage to carts that need to be relocated for various reasons. Furthermore, the cart transportation apparatus can comprise a means to facilitate secure cart movement for carts with a variety of wheel sizes.
US09452752B2
The present disclosure describes systems and methods for recharging a storage catalyst of an internal combustion engine. A method is described, comprising: while operating an engine in a substoichiometric operating mode when the engine is under medium load and responsive to an LNT condition, assisting the engine with an electric machine connected to an engine crankshaft. The electric machine provides an auxiliary drive to assist the engine in maintaining the substantially steady state substoichiometric operating mode which may be used to reduce NOx or SOx build up in a storage catalytic convertor or to assay the condition of a storage catalytic convertor.
US09452745B2
A master cylinder for a controlled brake system, including at least one piston which is displaceable in a housing and is sealed with respect to a pressure chamber by a sealing element arranged in an annular groove of the housing, which pressure chamber is connectable to an unpressurized supply chamber by control passages formed in the piston. The piston 46 is formed in at least two parts, including a main body and an annular control element, the control passages being provided in the control element.
US09452733B2
A vehicle-mounted control system to prevent an execution of an improper request of a center apparatus is provided. The vehicle-mounted control system executes an impropriety determination process, which determines whether a center request signal is an improper signal, based on circumstance information representing a circumstance where a vehicle is placed. Accordingly, it may be possible to determine whether the center request signal is an improper signal transmitted by an operation of a center apparatus by an improper person. When it is determined as the improper center request signal (S2: No), a vehicle control based on the center request signal is not executed.
US09452730B2
A vehicle far side airbag device includes: a splitting portion at a front side of a seat cover, at a side section at a vehicle center side of vehicle seatback, extends along a height of the seatback; an airbag inside the side section, deploys toward an outside of the side section while splitting the splitting portion, to protect an occupant from head to abdomen; a diffuser housed at a lower and rear side within the airbag, ejects gas from an inflator from an upper end opening and a lower end opening; and a tensioning cloth fixed to both a seatback frame and a location at a lower end of the splitting portion, is superimposed on the airbag in a stored state. A portion of the tensioning cloth is positioned further to a seatback lower side than the lower end opening of the diffuser in a deployed state.
US09452729B2
An inflator, especially for a protective device in a vehicle, includes a diffuser (10) which preferably forms a substantially rotation-symmetric external housing of the inflator with a closing member (12). The diffuser (10) includes more than 12, preferably more than 14, further preferably 23 discharge orifices (78) arranged in a row. Moreover, the inflator exhibits a plurality of further peculiarities.
US09452726B2
A method for recording vehicle-relevant data, in particular for detecting and evaluating damage to a vehicle in which structure-borne noise caused by an event, such as damage or contact, is detected and evaluated. The noise is recorded with its entire frequency spectrum, the frequency spectrum is divided into a lower frequency range and an upper frequency range, and an event is characterized by at least one amplitude in the upper frequency range. The event having an amplitude in the upper frequency range is included in an envelope curve analysis, in which a lower power density and upper power density are determined for a lower and upper frequency range, respectively. A relative measured value is determined from the ratio of the upper power density to the lower power density, an evaluation of the event is made by means of the relative measured value, and the event is stored.
US09452723B2
An energy absorption structure for a vehicle has an energy absorption element, in particular an engine longitudinal carrier, and at least one impact transmission element, which impact transmission element is pressed against a side wall of the engine longitudinal carrier and, in the event of an impact, is guidable along the side wall, wherein the engine longitudinal carrier is a fiber composite component and the impact transmission element has a microstructure which can be countersunk into the engine longitudinal carrier.
US09452721B2
Systems, methods, and apparatus are disclosed for generating power for a vehicle. A power generator may include a first loop configured to be deployed from a portion of a vehicle. The power generator also includes a first plurality of resistive devices coupled to the first loop, at least one resistive device of the first plurality of resistive devices being configured to transfer a force to the first loop. The power generator may also include a pulley coupled to the first loop, the pulley being configured to receive the force transferred to the first loop, and the pulley being further configured to rotate in response to receiving the force from the first loop. The power generator may also include a generator coupled to the pulley, the generator being coupled to an electrical system, and the generator being configured to deliver power to the electrical system in response to the pulley rotating.
US09452713B2
A modular mounting system for running board assemblies including at least one universal mounting bar and at least one universal mounting arrangement for connecting to a body panel of a motor vehicle. The universal mounting bar includes at least a first plurality of apertures which correlate to mounting apertures in the vehicle body panel, and a second plurality of apertures which correspond to mounting apertures in a second discreet vehicle body panel, and a third plurality of apertures which correspond to mounting apertures in a third discreet vehicle body panel. The universal mounting bar provides a single bar that accommodates various aperture locations for body panels on any number of predetermined vehicles brands/models. Each universal mounting arrangement has at least one fifth plurality of apertures for connecting to each of a fourth plurality of apertures at predetermined locations on the universal mounting bar.
US09452706B2
A maneuvering aid for a vehicle has a lighting device configured to at least partially illuminate at least an underlying surface under the vehicle and/or a vehicle bodywork. A control device configured to control the lighting device in order to activate and/or deactivate same. The control device is configured to control the lighting device at least as a function of a vehicle speed and/or of a vehicle acceleration and/or of a distance of the vehicle from a roadway boundary or an obstacle in the roadway. A corresponding method, a corresponding vehicle, and a headlight assembly are described as well.
US09452704B2
A lighting device for vehicles having an optical fiber including a flat segment with two opposing flat sides, a light decoupling area, and a light coupling area. The light decoupling area in which light relayed by the flat sides is output in the primary direction of emission. The light coupling area couples the light into the optical fiber, and is arranged on a free end of a light coupling element which is perpendicular to the flat segment and projects from the same. A deflection structure is arranged between the light coupling element and the flat segment for the purpose of deflecting the light toward the flat segment. A rigid circuit board runs parallel to the flat segment. The circuit board is configured with a number of light sources which are each functionally assigned to the light coupling elements.
US09452700B2
A method for manufacturing a suspension mat 1, the suspension mat 1 comprising at least one wire 10 for mounting the suspension mat 1 to a seat frame 100; the method comprising the steps of (a) pushing a plastic tube 20 in a first direction 52 onto an initially straight end portion 12 of the wire 10, while setting free an uncoated outer end 14 of the straight end portion 12; (b) bending the uncoated outer end 14 of the straight end portion 12 to form an uncovered hook 16; and (c) shifting the plastic tube 20 in a second, reverse direction 54 onto the bent hook 16, such that the plastic tube 20 surrounds the bent hook 16 and forms a plastic covered hook 18. The present invention also relates to a suspension mat 1 produced in accordance with the method and an apparatus 70 for manufacturing a suspension mat 1.
US09452698B2
A center backrest assembly having a main body which is mounted in the vehicle interior so as to be pivotable between an upright backrest position and a lowered functional position. The main body includes a head region which in the backrest position is positioned at the top. The head region on at least one lateral face has a lateral part which is mounted on the main body so as to be movable between a bearing position which bears on the head region and a laterally deployed deployment position.
US09452697B2
A seat device for a vehicle is provided in which a dynamic damper is formed of a weight and an elastic member supporting the weight so as to be capable of vibrating, and the elastic member is retained on a frame or a cushion member of a seat installed in the vehicle, wherein the weight is formed into a polyhedron whereas the elastic member is formed into a sheet shape, and the weight is covered and supported by the sheet-shaped elastic member. This enables the weight to be supported simply by the elastic member, and the dynamic damper to be provided at low cost.
US09452696B2
A seat reclining apparatus includes a base plate, a ratchet plate, a lock member guided by a guide groove of the base plate between engaged and disengaged positions, a first cam between the base plate and the ratchet plate, and a second cam which moves toward and presses the lock member to an engaged position by the first cam when the first cam rotates from the unlocked to locked positions. The second cam includes a surface contact portion which comes in surface contact with a guide surface in the guide groove, an engaging portion which is pressed by the first cam, and a pressing portion which presses a pressed portion of the lock member. One and the other of the pressing portion and the pressed portion respectively includes a flat surface and a curved surface that is convex toward the flat surface.
US09452693B2
A seat for use in a passenger vehicle, e.g. for prisoner transport, comprises a molded piece having at least one first contact zone at a periphery of the molded piece and at least second contact zone located inward of the periphery of molded piece. The second contact zone may comprise a multi-surface formation that is configured to engage a multi-surface formation of a vehicle body. The molded piece may comprise one or more recesses designed to accommodate the body of a passenger. The at least one second contact zone may be disposed in an area of the seat that receives the buttocks of a passenger, thereby providing additional support in a load bearing area of the seat.
US09452687B2
A method for controlling a cold start of a fuel cell vehicle includes detecting and storing temperatures at an inlet and an exit of fuel cell cooling water a plurality of times after turning-off of the fuel cell vehicle. A start sequence is controlled based on the lowest temperature of the stored temperatures and temperatures at the inlet and exit of the cooling water at a restart of the vehicle. Accordingly, it is possible to enhance start-up stability and driving stability by controlling a cold start sequence according to an internal state of the fuel cell stack.
US09452671B2
An energy storage system comprising at least one energy storage module adapted to supply electrical energy to a hybrid vehicle. The energy storage module comprises an enclosure, at least one battery array located within the enclosure, and an energy storage controller module located within the enclosure and electrically connected to the battery array. The energy storage module further comprises a compliant tipped thermistor which may be installed within a flexible clip. The thermistor is positioned to monitor the temperature of one or more of the batteries within the energy storage system.
US09452669B2
An all-terrain vehicle has a frame unit including upper side tubes and lower side tubes. Front and rear ancillary tube assemblies are connected between the upper side tubes and the lower side tubes in the front and rear parts. A power unit is fixed to the lower side tubes. A heat dissipation member for cooling the power unit is mounted to the front part of the frame unit. The power unit has an air inlet port to which a cooling duct is coupled. A steering mechanism is arranged in an internal area delimited by the upper side tubes and the lower side tubes between the heat dissipation member and the power unit and includes a steering bar, an electronic steering assisting device, and a steering arm. The cooling duct and the electronic motor are respectively set on opposite sides of a steering bar center axis of the steering mechanism.
US09452668B2
A mounting frame (20) for an electrically driven motor vehicle (10) has two longitudinal beams (30, 32) oriented in a longitudinal direction (18) of the motor vehicle (10). An electric drive unit (22) for driving the motor vehicle (10) is mounted on the longitudinal beams (30, 32). The longitudinal beams (30, 32) form a frame arrangement that is open out in the longitudinal direction (18). A flexurally stiff hollow body (28) is formed separately from the longitudinal beams (30, 32) and is fixed to the mounting frame (20). The hollow body (28) is arranged between the longitudinal beams (30, 32) and is mechanically fixedly connected to the longitudinal beams (30, 32) to form a closed frame section.
US09452665B2
A roof arrangement (3) of a motor vehicle is stowable and, in a closed position, extends between an upper windshield cowl and a fixed rollover hoop (6). The roof arrangement (3) has a roof frame (4) which is articulated, via a linkage (11, 13), in a mount (11) that is fixed with respect to a bodyshell. Seals (17) run on both sides of the roof frame (4) and form seal strands in the closed position of the roof arrangement. Each seal (17) is divided into three over its length. A front portion (18) of the seal (17) is fastened to the roof frame (4), a middle portion (19) of the seal (17) is fastened to a link (11) of the linkage (11, 13) and a rear portion (20) of the seal (17) is fastened to a rear surface bow (5).
US09452663B2
The present invention discloses a shading device includes a screen, a shaft portion having a lock portion to be locked, a biasing mechanism, a locking member that is engaged at a lock position with the lock portion, and a housing in which the end portion of the shaft portion is inserted. The housing has a sliding guide portion in which the locking member is slid. The sliding guide portion is capable of guiding the locking member in a direction passing through the lock position and a lock release position, and has a lock position engagement portion for stopping the locking member from sliding at the lock position. The locking member includes a slide engagement portion that engages with the lock position engagement portion at the lock position and an operating portion that can be flexed to release the slide engagement portion from the lock position engagement portion.
US09452662B2
A method for bending a sheet is described. The method includes the following steps: a) at least one sheet is inserted into a pre-bending ring with a movable bending ring holder, the at least one sheet is heated at least to an approximately softening temperature, and the at least one sheet is prebent in the pre-bending ring to 5% to 50% of a final edge bending, b) the pre-bent sheet is lifted out of the pre-bending ring by means of a suction device and is bent further, beyond a bending obtained in the pre-bending ring, c) the at least one sheet is laid down by means of the suction device in a final-bending ring on the movable bending ring holder and the at least one sheet is bent to a final bending, and d) the at least one sheet is cooled down in the final-bending ring and the at least one sheet is bent by means of the suction device to 100% to 130% of an overall final edge bending.
US09452659B2
A system and method for controlling a combined heating and cooling vapor compression system are provided. The apparatus may be a vehicle and may include a cabin, a vehicle battery, a Rechargeable Energy Storage System (RESS), and a vapor-compression system, having at least one controller, operable in a variety of modes selectable to facilitate cooling, heating, and dehumidification of the vehicle cabin. The method may include steps to adjust evaporator air temperature to control comfort, fogging and smell in the cabin by adjusting the compressor speed; regulate heat pump performance by adjusting the output of an electric heater and adjusting the flow of coolant through the RESS chiller; and evaluating and optimizing the discharge pressure and suction pressure of the compressor by adjusting the compressor speed and adjusting the coolant flow through the RESS chiller.
US09452658B2
A convertible link for use with an anti-sway bar is provided. The convertible link includes a hydraulic cylinder having a link tube and a fluid shaft. The fluid shaft includes a piston coupled to a first end of the fluid shaft, wherein the fluid shaft and the piston are slidably coupled within the link tube. Fluid flows in and out of the hydraulic cylinder to move the hydraulic cylinder between a fixed and a moveable condition. In the fixed position the fluid shaft does not move with respect to the link tube and the anti-sway bar is operational to control roll. In the moveable condition the fluid shaft is moveable with respect to the link tube and the anti-sway bar is not operational to control roll.
US09452645B2
A tire inflation system having a spindle that has a spindle fastener hole and spindle passage through which a pressurized gas flows for inflating a tire. An adapter or a fastener tube may inhibit pressurized gas from flowing from the spindle passage into the spindle fastener hole.
US09452644B2
A tire inflation system having a spindle that is configured to support a wheel bearing. A passage for routing pressurized gas may be provided with the spindle or with a sleeve that may be disposed on the spindle.
US09452641B2
A recreational vehicle includes two parallel wheels installed at a front wheel set or a rear wheel set, and the axes of the two wheels are not configured to be aligned on the same horizontal line, and the two wheels are installed at a frame through an adjusting module movable with respect to the frame, and a fixing module is installed between the frame and adjusting module for controlling whether to move the adjusting module with respect to the frame. The recreational vehicle is capable of adjusting the width of the rear wheel that touches the ground to enhance the variability, adaptability and practicality of the vehicle.
US09452640B2
An axle alignment system for a multi-axle trailer includes a mounting bracket, a mounting pin, at least one original equipment spacer, and at least one adjustable spacer. When the mounting bracket is utilized with the mounting pin and the original equipment spacer, the axle alignment system will only exclusively assume a nonadjustable, standard configuration. In contrast, when the mounting bracket is utilized with the mounting pin and the adjustable spacer, the axle alignment system will be activated and assume one of multiple possible adjusted configurations allowing one to align an axle of a multi-axle trailer.
US09452639B2
Axle shaft assemblies for use with a vehicle include a tubular shaft formed from a material having a first modulus of elasticity. A first insert is positioned within the longitudinal cavity of the shaft at a first end, the first insert having a thickness adapted to provide the first end tubular shaft with a greater modulus of elasticity for providing a suspension characteristic to the vehicle. A second insert having the selected thickness is positioned at a second end of the shaft. Interchangeability of the inserts enables a single lightweight shaft of generally thin, continuous wall thickness to be adapted with a variety of suspension characteristics, without replacing the shaft itself, while the low modulus of elasticity of the shaft facilitates the flexibility of the axle assembly and the ability of the axle to withstand impacts without deformation.
US09452626B2
An inkjet printer including an inkjet head, a head scanning unit, a wave shape generating mechanism to deform a recording medium into a predetermined wave shape, an obtaining device to obtain information concerning a type of the recording medium to be used in a printing operation, a gap information storing device to store gap information related to a gap between an ink discharging surface and the recording medium in association with a predetermined type of the recording medium, the gap information being acquired from a predetermined range in the recording medium, and a correcting device to correct the gap information according to the type of the recording medium obtained by the obtaining device when the type of the recording medium obtained by the obtaining device is different from the predetermined type of the recording medium stored in association with the gap information, is provided.
US09452623B2
A table for a flatbed printer comprises an upper plate (4) and a lower plate (6) separated by an intermediate layer (8). The intermediate layer is configured to provide a fluid flow path (34) that promotes a flow of fluid alternating between a position adjacent the upper plate and a position adjacent the lower plate, so as to promote heat transfer between the upper plate and the lower plate. The fluid flow path may be formed using a plurality of holes (26) in the intermediate layer. A method of manufacturing the printer table is also described.
US09452619B2
An image recording device is provided, having a recording unit configured to record an image on a sheet, and a tray disposed below the recording unit. The tray includes a sheet holding surface configured to hold the sheet. Additionally, the image recording device includes a sheet feeder disposed between the recording unit and the tray. The sheet feeder includes a roller for feeding the sheet from the tray. The roller is configured to move between a first roller position in which the roller contacts the sheet holding surface of the tray and a second roller position in which the roller is separated from the sheet holding surface. A return guide, disposed between the recording unit and the sheet feeder, defines a second conveying path to guide the sheet having an image recorded on one side thereof back to the feed guide. The return guide has a first opening configured to accommodate the roller of the sheet feeder when the roller is in the second roller position.
US09452616B1
A system for printing an image on a surface may include a robot having at least one arm. A printhead may be mounted to the arm and may be movable by the arm over a surface along a rastering path while printing an image slice on the surface. The image slice may have opposing side edges. The printhead may be configured to print the image slice with an image gradient band along at least one of opposing side edges wherein an image intensity within the image gradient band decreases from an inner portion of the image gradient band toward the side edge.
US09452613B2
An inkjet printer 1 has an elastic ink pack 10 that holds ink, and an ink supply mechanism 5 that pressurizes the ink pack 10 and supplies ink to the ink path 4 side. The ink supply mechanism 5 has a pressure pump 15; a remaining ink monitor 52 that watches if the ink in the ink pack 10 has dropped to a specific remaining ink level; a first pressure control unit 56 that drives the pressure pump 15 until the pump pressure reaches a preset first set pressure P1 when the remaining ink has not reached the specific remaining ink level; and a second pressure control unit 57 that drives the pressure pump 15 until the pump pressure reaches a second set pressure P2 that is higher than the first set pressure P1 when the remaining ink has reached the specific remaining ink level.
US09452610B2
A technique of enhancing attachment of a liquid supply unit to a liquid ejection device is provided. A first cartridge 100a and a second cartridge 100b are attached to a carriage 27 of a printing device 27 via a holder structure 200. The holder structure 200 has a lever member 230 rotated and moved to engage with a main engagement part 120 of each of the first and the second cartridges 100a and 100b. Each of the first and the second cartridges 100a and 100b has a first side wall portion 125 and a second side wall portion 126 configured to press the lever member 230 and rotate and move the lever member 230 forward in the course of attachment of the first or the second cartridge 100a or 100b to the holder structure 200. A rotation axis RX of the lever member 230 is located at a position closer to an ink supply port 110 or 110a than the first side wall portion 125 and the second side wall portion 126 in the course of attachment of the first or the second cartridge 100a or 100b.
US09452606B2
A liquid ejection head includes a plurality of ejection members, each having an ejection port for ejecting liquid, an element for ejecting a liquid from the ejection port, a liquid chamber for storing liquid to be supplied to the ejection port and a heater for heating liquid, and a base substrate bearing the plurality of ejection members arranged thereon and having a common flow channel for supplying liquid to the plurality of liquid chambers. The common flow channel communicates with the liquid chambers by way of respective branch ports and each of the branch ports is provided with a notch portion at the upstream side thereof as viewed in the flow direction of liquid flowing through the common flow channel and the upstream side of each of the branch ports has a profile asymmetric with regard to a straight line passing through the center of gravity of the branch port and extending in the flow direction.
US09452598B2
The present invention is in the field of multiple layer glass panels comprising a polymer sheet having desirable surface properties, and more specifically, the present invention is in the field of multiple layer glass panels comprising poly(vinyl butyral) having a finished surface of relatively low waviness and high roughness disposed in contact with poly(ethylene terephthalate) and/or other poly(vinyl butyral) type layers.
US09452593B2
A melt-blend resin composition prepared by melt-blending includes from 60 parts to 99 parts per hundred weight resin in the blend of an amorphous cycloolefin polymer composition exhibiting a glass transition temperature in the range of from 30° C. to 200° C.; and from 40 parts to 1 part per hundred weight resin in the blend of a partially crystalline, cycloolefin elastomer of norbornene and ethylene preferably having a glass transition temperature in the range of from −10° C. to 15° C. and a crystalline melting temperature in the range of from 60° C. to 125° C. and a % crystallinity by weight in the range of from 5% to 40%. The partially crystalline, cycloolefin elastomer optionally has a second glass transition temperature at less than −90° C.
US09452592B2
The present invention is directed to a multilayer film having an active oxygen barrier layer that comprises an oxygen scavenging composition that is a blend of a thermoplastic resin (A) having carbon-carbon double bonds substantially in its main chain, a transition metal salt (B), and an oxygen barrier polymer (C) having oxygen barrier properties that can be further enhanced by exposing the composition to a source of ionizing radiation e.g., electron beam radiation. Irradiation improves the oxygen scavenging abilities of the oxygen scavenging composition so that oxygen can be intercepted and scavenged as it passes through the film. The resulting irradiated multilayer film has improved active barrier properties in comparison to the same film prior to irradiation. As result, the multilayer film of the present invention can be used in packaging applications to help maintain a low oxygen atmosphere in the interior of a package.
US09452588B2
An adjustable shim comprises a stack of plies comprising plastics material reinforced with a three-dimensional fiber layer, the plastics material being flowable under compressive force prior to cure for adjusting the thickness of the shim. The shim may be used to fill a void between two structural components joined together. Also, a method of filling a void between two structural components using the shim. The shim is easy to handle, can easily be laid up to a variety of thicknesses, and is quick to cure (depending on the plastics material used). The three-dimensional fiber layers make the shim highly compressible prior to cure, and provide significant reinforcement to the plastics material of the plies to support compressive stresses in the shim post cure.
US09452585B2
An automatic inspection device for a corrugated paperboard machine includes comprises a position setting section for setting movable members to positions within moving ranges; a control section for driving each of the drive motors at a given rotational speed so as to allow a respective one of the movable members to be moved within a corresponding one of the moving ranges; a current detection section for detecting a drive current being supplied to each of the drive motors when the drive motor is driven at the given rotational speed; and a current determination section for determining whether the drive current of each of the drive motors exceeds a given threshold. The automatic inspection device is configured to, when the current determination section determines that the drive current of a specific one of the plurality of drive motors exceeds the given threshold, detecting that a defect occurs in the movable member.
US09452578B2
A method for firing a green honeycomb ceramic body including heating the green honeycomb ceramic body from room temperature to a first temperature of less than or equal to about 350° C. with at least one heating rate of greater than or equal to about 80° C./hr. The green honeycomb ceramic body may be heated from the first temperature to a second temperature of greater than or equal to about 800° C. at a heating rate of greater than or equal to about 90° C./hr. The green honeycomb ceramic body may be heated from the second temperature to a third temperature of greater than or equal to about 1000° C. The green honeycomb ceramic body may include aluminum raw materials for forming an aluminum titanate ceramic body.
US09452570B2
An information handling system chassis is built at least in part from ceramic elements. For example, a transparent aluminum oxide ceramic portion covers a touchscreen to provide a rigid outer surface for accepting end user inputs. As another example, a ceramic chassis element has a ceramic material formed around a metal material of similar substance with bonding of the ceramic to the underlying material enhanced with oxidation of the outer surface of the metal material.
US09452567B2
A stereolithography apparatus includes a supporting frame assembly, a tank supported on the supporting frame assembly, a vertically moving module, and a build platform. The tank has an anchored portion anchored to the supporting frame assembly. The build platform is vertically moved relative to the tank by the vertically moving module. After a resin layer is solidified and adhered to the bottom of the tank and the build platform, the tank is peeled away from the resin layer starting from a portion of the resin layer adjacent to the anchored portion and partially moves upward relative to the supporting frame assembly around the anchored portion when the build platform leaves the supporting frame assembly. To further reduce the separation force between the cured resin layer and the tank, the bottom of the tank is covered with materials that are transparent, chemically resistant, impact resistant or/and elastic.
US09452560B2
A variegated capstock for covering a substrate for a building product has polymeric streaks in a non-clear, non-opaque matrix. Rapid cooling of the matrix minimizes formation of crystallites, such that the polymeric streaks become visible through a surface of the non-opaque matrix. The streaks are visible by having a color or an index of refraction different from that of the matrix. The matrix is in one or more layers, and the polymeric streaks are in the layers. The substrate is visible through the non-clear, non-opaque matrix and can appear partially obscured by the non-clear, non-opaque matrix.
US09452558B2
Mold apparatuses may comprise a mold body, a thermostat target area and a channel unit. Said thermostat target area may be defined in said mold body. The channel unit may comprise a thermostat channel which may be formed in said mold body and may be connected with the outside to maintain the temperature of said thermostat target area through the thermostat medium flowing through it, and a heat conductive partition disposed in the thermostat channel. Said thermostat channel may comprise a first channel located on one side of said heat conductive partition; a second channel located on the other side of said heat conductive partition; a first port connected with said first channel and the outside; a second port connected with said second channel and the outside; and a connect channel away from the first port and the second port and connected with said first channel and said second channel.
US09452554B2
A molded product manufacturing method and a molded product manufacturing apparatus are realized, each of which has improved quality and productivity of a molded product. A pressure to be applied to an upper mold (ML) and a lower mold (ML) is reduced in stages during a process from a start of decrease in internal temperatures of the upper mold (ML) and the lower mold (ML) to a complete mold-release of a resin component (W). This prevents an excessive load from being applied to the resin component (W) which has been molded but has not been mold-released.
US09452552B2
A pressure-controlling foam molding method and a device thereof. The device includes a first mold and a second mold positioned on different levels. The first mold molds polymer material into a blank and is opened in a high pressure environment to limit the extent to which the molded blank foams. The foamed blank is compressed to have a volume approximately equal to or smaller than that of the second mold cavity of the second mold. Then the foamed blank is moved from the first mold pit of the first mold into the second mold pit of the second mold along a moving axis parallel to gravity line. Prior to transfer, with the plane on which the opening of the second mold pit is positioned as a projection face, the shape and position of the opening of the second mold pit correspond to vertical projective shape and position of the blank.
US09452538B2
A movable robotic structure including a frame or substrate, an outer skin connected to at least a portion of the frame and a vacuum source in fluid communication with the outer skin. The vacuum source, such as a vacuum pump, is activated to pull the outer skin into engagement with an outer surface of the frame. When pulled by the vacuum source, the skin may conform to the topography or texture of the frame, as well as become taut over at least a portion of the frame.
US09452535B2
A self-aligning piston is configured to selectively engage and disengage a pipe segment to permit a top drive output shaft to be coupled to the pipe segment. In one embodiment, the self-aligning piston includes a piston body configured to rotate between a first position and a second position, at least one resilient, energy-storing member coupled to the piston body, a roller assembly coupled to the piston body, and a cam disposed between the at least one resilient, energy-storing member and the roller assembly. The resilient, energy-storing member is configured to bias the piston body into the first position by rotating the roller assembly along the cam.
US09452532B2
A robot determines whether or not an operator or an object is jammed between a robot arm and an external structure, classifies an area in which an end portion of the robot arm moves into a restricted area and an unrestricted area, and sets a restriction period. If a period after detection of the jam is in the restriction period and the end portion is in the restricted area, restriction on movement is imposed on one or more joints of the robot arm. The restriction on movement is a stoppage of movement of one or more joints. If the period after detection of the jam is after the restriction period, the restriction on movement is removed. If the period after detection of the jam is in the restriction period and the end portion is in the unrestricted area, the restriction on movement is not imposed on the joints.
US09452530B2
The disclosure includes a system and method for determining a robot path based on user motion by determining a current position of a robot with a processor-based computing device programmed to perform the determining, receiving sensor readings on positions, directions, and velocities of a visually-impaired user and other users, generating a model of the motions of the visually-impaired user and the other users, the model including a user path for the visually-impaired user and a robot path for the robot, generating a collision prediction map to predict collisions between at least one of the robot, the visually-impaired user, and the other users, determining whether there is a risk of collision for either the visually-impaired user or the robot, and responsive to the risk of collision, updating at least one of the user path and the robot path.
US09452528B1
A device and method is provided for controlling a mechanism in communication with a handheld device. The method includes sensing a maneuver of the handheld device and providing at least one vector command to the mechanism based on the sensed maneuver in order to control the mechanism.
US09452526B2
Provided is a robot cleaner. The robot cleaner includes a main body defining an outer appearance of the robot cleaner, a moving unit for moving or rotating the main body, a plurality of receiving units disposed in the main body to receive a user's voice command, and a control unit recognizing a call command occurring direction when the voice command inputted from the plurality of receiving units is a call command. The control unit controls the moving unit so that the main body is moved in the recognized call command occurring direction along the preset detour route.
US09452509B2
A sapphire pad conditioner includes a sapphire substrate having multiple protrusions on a surface and a holder arranged to hold the sapphire substrate. The sapphire substrate is used for conditioning a chemical mechanical planarization (CMP) pad.
US09452492B2
Systems and methods for forming apertures in microfeature workpieces are disclosed herein. In one embodiment, a method includes directing a laser beam toward a microfeature workpiece to form an aperture and sensing the laser beam pass through the microfeature workpiece in real time. The method can further include determining a number of pulses of the laser beam and/or an elapsed time to form the aperture and controlling the laser beam based on the determined number of pulses and/or the determined elapsed time to form a second aperture in the microfeature workpiece.
US09452488B2
A method of forming a golf club head assembly includes aligning a faceplate with a recess of a club head; welding the faceplate to the club head; then, after welding the faceplate, heating the club head and faceplate to at least a solvus temperature of the faceplate for a predetermined amount of time; and then, after heating the club head and faceplate, allowing the club head and faceplate to air cool.
US09452480B2
In some embodiments, a method and/or system may include a reciprocating saw system. The reciprocating saw system may include a housing and a reciprocating blade. The system may include an elongated member. When activated the elongated member may move from a first position to a second position such that a workpiece is positioned adjacent at least a portion of the housing and the reciprocating blade. The system may include a tension mechanism coupled to the elongated member. When the tension mechanism is activated the elongated member may move from the first position to the second position. In some embodiments, the system may include an engaging mechanism. The engaging mechanism, when activated, releases a first stop positioned distally on the housing. In some embodiments, when the first stop is released, when a tensile force is applied to the conveyor, the conveyor moves proximally moving the elongated member to the second position.
US09452462B2
In accordance with the present invention there is provided a method of making a metal part assembly, the method comprising: —providing a first metal part and a second metal part wherein at least one of the first and second metal part comprises a metal panel; —providing an adhesive sheet having a first portion near a first end of the adhesive sheet and a second portion near a second end opposite to the first end of the adhesive sheet, the adhesive sheet comprising a thermosettable composition that comprises a mixture of a first and second epoxy compound and an epoxy curing agent, wherein the first epoxy compound has a weight average molecular weight of at least 1000 g/mol and has an amount of epoxy groups of between 5 and 10 mole % and the second epoxy compound has a weight average molecular weight of not more than 400 g/mol and wherein the weight ratio of first to second epoxy compound is between 0.8 and 4; —adhering said first and second metal part together such that the adhesive sheet is provided between said first and second metal part thereby forming a metal joint; and heating the metal joint so as to cause thermosetting of the thermosettable composition of the adhesive sheet.
US09452461B2
A press forming apparatus (1a) consecutively carries out: a first step of pushing a flat plate-shaped workpiece into a die (14) by a forming punch (11), to form the workpiece into a cup-shaped workpiece (B); a second step of making the cup-shaped workpiece (B) move relatively to a position where a space (S2) is formed between a cup bottom part (B2) and the forming punch (11) by a holding down member (12) abutting on an end part of a cup vertical wall part (B1); and a third step of making a counter punch (13) approach the forming punch (11), to push a cup bottom part (B2) to a forming punch (11) side so that the cup bottom part (B2) is compressed by the forming punch (11) and the counter punch (13), making a material of the cup vertical wall part (B1) flow to a cup shoulder part (B3), thereby to thicken the cup shoulder part (B3).
US09452456B2
A substrate treatment plant includes a process chamber delimited by chamber walls and in the process chamber a substrate conveying unit for the horizontal conveyance of slab-shaped substrates in one conveying plane and in one conveying direction. The substrate conveying unit includes an arrangement of rotatably mounted, cylindrical conveying rollers transversely arranged to the conveying direction, the topmost generatrices of the conveying rollers defining the conveying plane, and at least one substrate treatment unit, which is located above the conveying plane, and at least one gas inlet. In the region of the substrate treatment unit at least one additional heating unit is located below the conveying plane and a condensation unit is located under the substrate conveying unit.
US09452452B2
A liquid processing apparatus according to the present disclosure includes a substrate holding unit configured to be rotated and hold a substrate from a bottom side thereof with substrate being spaced apart horizontally, a rotation driving unit configured to rotate the substrate holding unit, and an air supply unit provided above the substrate and configured to supply air toward the substrate held by the substrate holding unit. The liquid processing apparatus also includes an air supply path including a suction port that inhales the air supplied from the air supply unit and supplies the air inhaled from the suction port to a space formed between the substrate holding unit and a bottom surface of the substrate held by the substrate holding unit.
US09452451B2
The invention relates to a cleaning device (1) for an atomizer (2) having a specified outer contour, in particular for cleaning a rotary atomizer (2), comprising at least one cleaning brush (5) for cleaning the atomizer (2), wherein the cleaning brush (5) has a specified brush contour. According to the invention, the brush contour of the cleaning brush (5) is adapted to the outer contour of the atomizer (2) so that the cleaning brush (5) nestles up against the atomizer (2). The invention further relates to a corresponding cleaning brush (5) and to a suitable cleaning method.
US09452445B2
A method for producing an aircraft structure component is disclosed the component having an outer skin provided with a smooth outer surface. The method includes providing an aircraft structure component having an outer skin including at least one recess, detecting the location of said at least one recess by a recess detecting device, and filling said at least one recess at the detected location with particles of a filling material, said particles of filling material being applied into said at least one recess by an ink jet printing device.
US09452440B2
A multi-chambered bottle includes first and second chambers, a metering stage, a pour spout and a cap. The metering stage includes first and second metering stage sections connectable to respective mouths of the first and second chambers. Each metering stage section comprises a nozzle having a liquid inlet orifice and a liquid outlet orifice, and a vent tube having an air inlet orifice and an air outlet orifice at opposite ends of the vent tube, the air inlet orifice to be disposed outside of the respective chamber and the air outlet orifice to be disposed inside of the respective chamber, the vent tube disposed relative to the nozzle such that a line crossing a center of the air inlet orifice and a center of the liquid outlet orifice forms an acute angle with a normal axis of the bottle.
US09452436B2
The present invention relates to a drive head for detachable connection of a drive with a rotor of a centrifuge, comprising a base body, which is rotatable about an axis of rotation (R) and at least two coupling elements, which are mounted on the base body so as to be able to swivel out to the outside about a respective swivel axis. The swivel axes are tilted at an angle (α) with respect to the axis of rotation (R), and the coupling elements have a resting surface at their swiveling end, which extends perpendicularly to the axis of rotation (R). The present invention further relates to a kit comprising the drive head and a centrifuge comprising the drive head or the kit.
US09452435B2
An internal combustion engine and centrifugal separator assembly separates contaminants from crankcase gas. A crankcase is connected to the centrifugal separator including a centrifugal rotor. A rotor housing delimits a separation space in which the centrifugal rotor is arranged to rotate. A gas inlet conducts crankcase gas to a central part of the centrifugal rotor. A gas outlet communicates with a part of the separation space surrounding the centrifugal rotor and to conduct cleaned crankcase gas out of the separation space. A particle outlet communicates with the part of the separation space. The particle outlet is connected to a collector for the separated particles. The collector is configured to communicate with the gas inlet via a connection to provide a pressure difference between the particle outlet and the collector. The separated particles are drawn out of the particle outlet and into the collector during operation of the centrifugal separator.
US09452429B2
A method for performing multiplexed bead-based immunoassays using a microfluidic cassette capable of detecting a particle passing in substantially single file through an interrogation zone and generating a Coulter effect signal responsive to a characteristic of the particle. A fluid sample may be prepared by associating antibody-coated beads of different sizes to particles of interest. A first multiplexing option may be based on bead size, in which case the intensity of the Coulter signal is used to sort or characterize the particles. A second multiplexing option may be based on detection of Stokes' shift phenomena, or even simply emission intensity, in which case particles may be characterized responsive to intensity of the signal resulting from detection of radiation. The first and second multiplexing options may be employed together to populate an array of particle characteristics.
US09452424B2
ZSM-18 is synthesized from a mixture comprising water, a source of an oxide of a tetravalent element (Y), a source of an oxide of a trivalent element (X), a source of a first cation Q selected from either butamethonium cations or N,N,N,-trimethyl-N-butylammonium cations and a source of at least one second cation M, wherein the second cation M is selected from lithium, strontium, sodium, tetraalkylammonium and mixtures thereof when the first cation, Q is butamethonium cations, and wherein the second cation M is tetramethylammonium when the first cation Q is N,N,N,-trimethyl-N-butylammonium cations.
US09452421B2
A method of making a catalyst comprises: mixing three or more catalytically active components with water to form an impregnating solution; contacting a support with the impregnating solution; impregnating the catalytically active components onto the support to form an impregnated support; and calcining the impregnated support to form a catalyst. Another method of making a catalyst comprises: co-impregnating a support with three or more catalytically active components in an impregnating solution to form an impregnated support; and calcining the impregnated support to form the catalyst.
US09452412B2
A packing element (1) for use in mass and/or heat transfer processes through which at least one liquid may flow, wherein the packing element (1): has an outer surface (2) comprising three or more outer arched rib elements (21) and two outer connecting edge elements (22), optionally has an inner surface (3) comprising optional inner arched rib elements (31), wherein the element 1 is substantially spherical or substantially ellipsoidal, and wherein the outer connecting edge elements (22) and the outer arched rib elements (21) and optional inner arched rib elements (31) are embodied such that the total projected area (4) of the packing element (1) when viewed in any direction (7), preferably a radial direction (5) or optional axial direction (6), is partially open due to the presence of an open projected area (41), wherein it is open to an extent that ranges from about 15 to about 50, preferably about 17 to about 40, more preferably about 18 to about 35, most preferably about 20 to about 30% of the total projected area (4). The invention further relates to a method for producing said element (1). The present invention further relates also to a column or reactor comprising a bed of said elements (1), a method to prepare said bed, and the use of the element (1) or column or reactor in a mass transfer and/or heat transfer process and/or in a chemical reaction.
US09452411B2
The catalytic reactor with downward flow comprises a chamber (1) containing at least two solid catalyst beds (2; 11) separated by an intermediate zone comprising an essentially horizontal collecting plate (5) communicating with a vertical collecting pipe (7) for receiving fluids collected by the collecting plate, with a means for injecting a quenching fluid (8) emptying into the collecting pipe. An annular mixing chamber (9) is located below the collecting plate (5). A predistribution plate (11) is arranged below the chamber (9).The injection means (8) comprises a tubular portion that empties into the collecting pipe (7) in such a way as to inject quenching fluid in a direction forming an angle θ between 45° and 135° with the direction D from the axis of the mixing chamber measured at its input end.
US09452408B2
A method of starting up one or more units, the method comprising the steps of: (a) starting up a first unit including a microchannel reactor housing a Fischer-Tropsch catalyst by initially feeding a carbon monoxide source and a hydrogen source to the first unit and through the microchannel reactor; (b) processing, within the microchannel reactor, at least a portion of the carbon monoxide source and the hydrogen source; (c) monitoring at least one of internal pressure, temperature, and concentration at least one of within the microchannel reactor and downstream from the microchannel reactor; (d) at least partially containing the microchannel reactor using a wall of a containment device, the wall cooperating with the microchannel reactor to delineate at least one of a first inlet cavity and a first outlet cavity of the microchannel reactor, where at least one of the first inlet cavity and the first outlet cavity is not in fluid communication with at least one of a second inlet cavity and a second outlet cavity; and, (e) using the containment device to reinforce the integrity of the microchannel reactor.
US09452406B2
Disclosed are methods of preparing stable gas-in-water dispersions by silicic acid complexation of micron-sized gas bubbles, and stable dispersions prepared by silicic acid complexation. Compositions and products comprising the dispersions are also disclosed. Dispersions may be stable over an extended period of time at room temperature.
US09452402B2
Integrated Combustion Reactors (ICRs) and methods of making ICRs are described in which combustion chambers (or channels) are in direct thermal contact to reaction chambers for an endothermic reaction. Superior results were achieved for combustion chambers which contained a gap for free flow through the chamber. Particular reactor designs are also described. Processes of conducting reactions in integrated combustion reactors are described and results presented. Some of these processes are characterized by unexpected and superior results.
US09452399B2
The present invention describes a device and a method for dense and homogeneous loading of catalyst into the annular space 4 of bayonet tubes defined by an external tube 6 and an internal tube 5 used in a steam reforming reactor, said device using a rigid auxiliary tube 7 for introducing solid particles into said annular zone 4.
US09452378B2
Apparatus and method related to a cartridge filter having self-regulated pleat spacing. An elastic adhesive bead is used on an outer surface of a cylindrically formed pleated filter media to maintain pleat spacing without damaging the pleats or the filter media. In this way, a cylindrical pleated filter media may be formed from a planar filter media without the need for manually spacing the pleats during or after formation into a cylinder.
US09452377B2
A nanoporous ceramic membrane and preparation method thereof is provided. The nanoporous ceramic membrane is prepared by halloysite nanotubes (HNTs), and its porosity is between 35% to 85%. This method comprises steps as following: HNTs and polymers with a certain ratio are dispersed in organic solvent, and HNTs/polymer composite fibers are prepared through electrospinning method; after the HNTs/polymers composite fibers are laminated, they are sintered at high temperature in a certain or vacuum atmosphere, and a nanoporous ceramic membrane is obtained. Ceramic membrane prepared by this method is corrosion resistant, thermal resistant, and have large specific surface area, it may widely applied in the field of filtration, catalyst carrier and purification of high-temperature gas, etc.
US09452371B2
A method and a system for phase inversion of a dispersion are disclosed, the dispersion comprising a first fluid, said first fluid forming a disperse phase and a second fluid, said second fluid forming a continuous phase. The dispersion is supplied in a fluid supply device to a phase inversion means. Thereby the first fluid is transformed from the disperse phase into the continuous phase and the second fluid is transformed from the continuous phase into the disperse phase. The phase inversion means comprises an element providing a fluid contacting surface for coalescence in a direction of flow.
US09452370B2
The present invention describes a process for the separation of xylenes in simulated counter-current utilising at least one adsorber with a limited cumulated total height (Hcu) of adsorbent and a superficial velocity (Vsl) of less than 2 cm/s.
US09452362B2
Systems and methods of organizing a massively multiplayer online game (MMOG) via mobile units are provided. Features of mobile units such as messaging and location based services are incorporated into the game to enhance the user experience. The MMOG provides social networking opportunities to players by associating players based on similarities such as shared interests and activities. These shared interests and activities can be determined based on associations of the players in other situations, such as disparate online games or websites. In addition, advertising content can be provided to players based on similar factors. In an example implementation, the MMOG comprises a game similar to the offline game of tag, wherein players can “tag” each other through in-game interactions via the mobile units. These interactions can be triggered based on players being a fixed predetermined distance from each other.
US09452361B2
A network game system includes a game server in which a plurality of players respectively operating a plurality of portable communication terminals are registered in advance. When any one of the players logs in the game server through a communication network, a game is supplied to the portable communication terminal of the player. A game screen is shown on a display, and both characters in the course of logging-in and logging out are displayed on the game screen. If the player selects the logging-out character, a selection signal is transmitted to the game server. The game server transmits a log-in operation request to the portable communication terminal of the player operating the selected character.
US09452360B2
A multi-instance, multi-user animation platform includes a plurality of modeled parallel dimensions in a computer memory. Each of the parallel dimensions may be an independent model of a physical, three-dimensional space having corresponding features such that the parallel dimensions are recognizable as counterparts to each other. Avatars are located within corresponding ones of the parallel dimensions so as to prevent over-population of any one of the parallel dimensions by avatars. Avatars are animated within different ones of the parallel dimensions using input from respective users to provide virtual-reality data. A common space is modeled in the computer memory configured in relation to the plurality of parallel instances so that an object located inside the common space is visible from viewpoints located inside each of the plurality of parallel instances. Remote clients may output an animated display of a corresponding one of the parallel dimensions and avatars therein.
US09452359B2
A system and method provides gaming related and player/gaming attendant related services to a plurality EGM. Each EGM has an associated multipurpose EGM/player tracking device. Each multipurpose EGM/player tracking device has first and second ports. The first port couples the respective multipurpose EGM/player tracking device to the respective EGM using a communications link. The first port of one of the multipurpose EGM/player tracking devices may utilize a different communications protocol than another one of the advance player tracking device. A server computer is coupled the multipurpose EGM/player tracking devices using a system communications protocol through system communications links. The server computer provides gaming and player/gaming attendant services to users of the EGMs.
US09452356B1
A system and method for providing virtual items to users of an online game operated in a virtual space. Multiple users may participate in affiliations or alliances of discrete groups of users in an online game and may access the online game through client computing platforms associated with the users. The affiliations may have affiliation game units associated with affiliations which provide a benefit to the members of the online game. Affiliation members may cumulatively obtain affiliation game units and/or upgrade affiliation game units by providing one or more virtual items. Upgrading affiliation game units may require the cooperation of multiple members of the affiliation.
US09452346B2
A security system for a casino table card game has a casino table with i) indicia thereon for the placement of wagers, ii) a data entry system with an associated computer, and iii) sensors that can detect the placement of at least one specific category of wager; a shuffling device with a microprocessor integral to the shuffler for providing information regarding cards or hands; a central table gaming computer that receives information from the shuffler in real time, receives information from the sensors, and receives information from the data entry system, the associated computer, the microprocessor and the central table gaming computer communicating data among each other in real time.
US09452336B2
A tee for supporting a baseball comprising a longitudinal shaft comprising a first end and a second end, a base structure coupled to said first end and configured to rest on a surface, a mesh support connected to said second end of said shaft. The tee further comprising a coupler adapted to rigidly affix said mesh support to said second end of said shaft, wherein said shaft is adapted to change the distance of said mesh support above said surface.
US09452323B2
A golf club head for playing golf made by a method including providing a powdered metal, and applying a controlled source of energy to the powdered metal layer by layer to form a golf club head, wherein the golf club head is a hollow golf club head having a supporting lattice formed within the hollow golf club head.
US09452322B2
A football having a prolate spheroidal shape including longitudinally spaced apart first and second ends. The football is capable of being analyzed under computational fluid dynamics analysis, and includes upper and lower central regions. Each positioned between first and second upper and lower end regions, respectively. The football further includes a bladder, a cover, a plurality of boundary layer trip mechanisms coupled to the upper and/or lower central regions, and a lacing coupled to the upper central region. The analysis includes first and second configurations. The first configuration is conducted on the football with the trip mechanisms, and the second configuration is conducted on the football without the trip mechanisms. The first and second configurations provide first and second drag coefficients, respectively. The first coefficient is at least 3 percent lower than the second coefficient. The length of the upper and lower central regions is defined by the lacing.
US09452317B2
A software operated method/system for both breathing training and respiratory muscle training in which a user inhales and exhales via a mouthpiece through a hand-held breathing chamber so that pressure, time and direction of air breathed through the chamber is automatically measured. The breathing results are automatically processed and displaying on a remote screen as a real-time interactive graphic representing such air pressure, time and direction. The users base-line is established and a menu of training choices including interactive games is displayed.
US09452314B2
A treadboard and a treadmill includes two first elastic strips of same structure arranged abreast with the lengths disposed along the moving direction of the belt of the treadmill and a plurality of solid support strips; the first elastic strips are arc structural, the center of the arc structure is higher than two ends of the arc structure; either end of each first elastic strip is once formed with buffer portion that is flexible along the length direction, so that the buffer portions buffer the arc structure of the first elastic strip after fixedly connected to the base of the treadmill; the solid support strips is of straight strip structure respectively connected vertically between the two first elastic strips, two ends of each solid support strip are respectively connected to the corresponding upper sides of the two first elastic strips.
US09452305B2
A radiation-activated sprinkler includes a sprinkler body defining a main orifice, the main orifice adapted to couple to a source of pressurized liquid; a deflector coupled to the body; a valve adapted to seat on the main orifice to block the source of pressurized liquid; a linkage mechanism adapted to retain the valve on the main orifice; and one or more fusible links coupled to the linkage mechanism, wherein the one or more fusible links are located substantially externally with respect to the sprinkler body, deflector, and linkage mechanism. The one or more fusible links are adapted to release when exposed to an amount of radiation that exceeds a predetermined threshold, thereby releasing the linkage mechanism from the valve. Other features and related methods are also described.
US09452302B2
Various embodiments provide methods and systems for ultrasound treatment of tissue are provided. Accordingly, a method can include locating an implant in a site in a body, directing a medicant to at least one of the implant and the site, directing ultrasound energy to the site, and accelerating healing of the implant and/or native tissue at the site.
US09452295B2
The disclosure describes a method and system that allows a user to configure electrical stimulation therapy by defining a three-dimensional (3D) stimulation field. After a stimulation lead is implanted in a patient, a clinician manipulates the 3D stimulation field in a 3D environment to encompass desired anatomical regions of the patient. In this manner, the clinician determines which anatomical regions to stimulate, and the system generates the necessary stimulation parameters. In some cases, a lead icon representing the implanted lead is displayed to show the clinician where the lead is relative to the 3D anatomical regions of the patient.
US09452290B2
An implantable neurostimulator-implemented method for managing tachyarrhythmias through vagus nerve stimulation is provided. An implantable neurostimulator, including a pulse generator, is configured to deliver electrical therapeutic stimulation in a manner that results in creation and propagation (in both afferent and efferent directions) of action potentials within neuronal fibers of a patient's cervical vagus nerve. Operating modes of the pulse generator are stored. A maintenance dose of the electrical therapeutic stimulation is delivered to the vagus nerve via the pulse generator to restore cardiac autonomic balance through continuously-cycling, intermittent and periodic electrical pulses. A restorative dose of the electrical therapeutic stimulation is delivered to prevent initiation of or disrupt tachyarrhythmia through periodic electrical pulses delivered at higher intensity than the maintenance dose. The patient's normative physiology is monitored via a physiological sensor, and upon sensing a condition indicative of tachyarrhythmia, is switched to delivering the restorative dose to the vagus nerve.
US09452273B2
For cricothyrotomy and the like, a surgical device has, in one embodiment, a device body with a bi-directional scalpel, an end cap, and a tracheal hook that fits within a channel formed in the device body. With the end cap removed to expose the bi-directional scalpel blade and with the tracheal hook fully inserted within the body channel, the device can be held, e.g., in the dominant hand of an operator, and manipulated to make an opening in the patient's neck using the exposed scalpel blade. The tracheal hook can then be slid away from the device body with the hook's barbed tip entering the opening to enable the operator to easily and quickly secure the surgical airway. The design of the surgical device enables an economy of movements that otherwise would typically not be within the skill set of an operator who was not a surgeon.
US09452269B2
A method for stable support of a needle to be introduced into a patient, a body to be penetrated by the needle is arranged on the patient. The body is made of a substance corresponding in terms of its mechanical properties to body tissue (in particular corresponding to body tissue in terms of visco-elastic coefficients and density) and/or is made of a gel-like substance.
US09452252B2
The invention relates to a method and a device for monitoring a vascular access during an extracorporeal blood treatment. The method and the device according to the invention are based on the monitoring of the difference between the venous pressure measured by a venous pressure sensor and the arterial pressure measured by an arterial pressure sensor (in the extracorporeal blood circuit. According to the method and the device according to the invention, a test function describing disturbances in the extracorporeal blood circuit is determined. Said test function is used to determine a noise-free differential pressure from the measured venous and arterial pressure, said differential pressure being evaluated in an arithmetic and evaluation unit to identify a defective vascular access.
US09452249B2
A modular driveline includes a modular portion including a cable and a connector, the cable having terminations, and a percutaneous portion including a cable and a connector, the cable having terminations. The percutaneous portion connector couples to the modular portion connector, and cable terminations at the connectors are captured in the connectors by potting. The cable can include an inner member, conductors disposed about the inner member, a covering about the conductors, a layer extruded onto the covering, an armor braid over the extruded layer, and an outer jacket extruded over the armor braid.
US09452244B2
An apparatus for cleansing wounds with means for stressing the wound bed and optionally tissue surrounding the wound, in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing and a means for fluid cleansing and back to the dressing. The cleansing means (which may be a single-phase, e.g. micro-filtration, system or a two-phase, e.g. dialytic system) removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed. The means for stressing the wound bed and optionally tissue surrounding the wound promotes wound healing. The dressing and a method of treatment using the apparatus.
US09452241B2
A catheter assembly for insertion into the brain. The assembly comprises a first length of tubing made of a first material. A second material surrounds the first length of tubing, the second material being more flexible than the first material and having a hardness of less than 50 Rockwell E. The second material provides damping to the first length of tubing.
US09452240B2
Disclosed are pepsinized collagen implants, such as membranes and sponges, and methods of making them, which entails solubilizing pepsinized collagen in a buffer containing a polyol, e.g., mannitol or sorbitol, wherein the buffer has a substantially neutral pH. Methods of using the pepsinized collagen implants for clinical applications are also disclosed.
US09452239B2
Methods of fabricating a substantially interconnected model vasculature, as well as compositions formed from such methods are provided. In some embodiments, the methods may comprise forming a non-woven fiber network comprising a plurality of fibers and a void space; backfilling the void space of the fiber network; and removing the fibers to form a substantially interconnected vascular network.
US09452231B2
An apparatus for disinfecting an interior of a generally closed container having an opening has an elongated housing fittable through the opening, having a wall forming a reaction chamber, and having an inner end and an outer end longitudinally flanking the chamber. Thus when the outer end is tilted to the opening, the inner end is in the interior of the container. An ozone generator is provided in the chamber. A plurality of openings in the wall of the housing at the inner end conduct ozone from the chamber out into the interior of the container.
US09452229B2
The present invention relates to liquid mixtures and compositions having high bromine concentrations that find use as biocides and processes for preparing them.
US09452228B2
The present invention concerns compositions and methods of use of antibodies or antibody fragments that bind to an epitope located within the second cysteine-rich domain (Cys2, amino acid residues 1575-1725) of MUC5AC. The antibodies bind with high specificity and selectivity to pancreatic cancer and are of use for therapy, detection and/or diagnosis of pancreatic cancer. In preferred embodiments, therapeutic antibody may be conjugated to at least one therapeutic agent, such as 90Y. Both in vivo and in vitro detection of pancreatic cancer may be performed with the subject methods and compositions. Specific dosages of radiolabeled antibody and/or gemcitabine, of use in human pancreatic cancer patients, are disclosed herein.
US09452220B2
The present invention discloses coupling compounds of a structure as shown in Formula I, II or III formed by connecting NSAID anti-inflammatory and analgesic drugs and EGFR inhibitors by ester bonds or pharmaceutically acceptable salts or stereoisomers thereof or prodrug molecules thereof: where R is a NSAID anti-inflammatory and analgesic drug. In the present invention, the coupling compounds obtained by coupling NSAID anti-inflammatory and analgesic drugs with EGFR inhibitors have excellent therapeutic effects of tumors and provide new drugs for clinic treatment options.
US09452210B2
A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of influenza HA in plants and the purification by size exclusion chromatography. The invention is also directed towards a VLP comprising influenza HA protein and plant lipids. The invention is also directed to a nucleic acid encoding influenza HA as well as vectors. The VLPs may be used to formulate influenza vaccines, or may be used to enrich existing vaccines.
US09452209B2
The present invention provides an immunogenic influenza composition in a dose volume suitable for human use, comprising an influenza virus antigen or antigenic preparation thereof and an adjuvant composition comprising an oil-in-water emulsion, wherein said oil-in-water emulsion comprises a metabolisable oil at a level of below 11 mg and an emulsifying agent at a level of below 5 mg and optionally a tocol or a sterol at a level of below 12 mg. Suitably the amount of influenza antigen per strain per dose is 15 μg HA or a low amount such as less than 15 μg HA.
US09452203B2
The subject of the present invention is, in the most general aspect, the prevention and/or treatment of a secondary edema. In particular, the present invention relates to a C1-Inhibitor for use in a method of preventing the formation and/or reducing the size of a secondary edema of the central nervous system (CNS) in a subject wherein the subject has or has had at least one disorder selected from the group consisting of stroke, ischemic stroke, hemorrhagic stroke, perinatal stroke, traumatic brain injury and spinal cord injury. Preferably the secondary edema of the CNS is a secondary brain edema. Another subject of the present invention is the treatment of disorders associated with an increased permeability of the blood brain barrier or the blood spinal cord barrier. And a third subject is a plasma-derived C1-inhibitor for use in a method of preventing, reducing or treating brain ischemia-reperfusion injury.
US09452200B2
The present disclosure describes methods of treating angiogenic disorders of the eye, such as macular degeneration, restenosis following glaucoma treatment or diabetic retinopathy, by administering an activator of C-X-C chemokine receptor 3 (CXCR3). In some embodiments, the activator of CXCR3 is interferon-γ-inducible 10 kDa protein (IP-10) or a fragment or variant thereof, such as a fragment comprising or consisting of the C-terminal α-helix of IP-10. In other embodiments, the activator of CXCR3 is platelet factor 4 (PF4) or a fragment or variant thereof.
US09452198B2
The invention provides, inter alia, conjugates of a hydratable polymer (such as PEG, polyethylene glycol) and a lectin (such as wheat germ agglutinin, WGA), compositions comprising these conjugates, as well as methods and targeted uses of these conjugates and compositions for, e.g., lubricating, maintaining hydration of, rehydrating, and/or inhibiting microorganism colonization of a biological surface in need thereof.
US09452186B2
The invention provides improved methods for cell therapy. In particular, the invention provides therapeutic compositions of enhanced hematopoietic stem and progenitor cells having improved engraftment and homing properties, and methods of making the therapeutic compositions. The invention further provides methods of improving the efficacy of hematopoietic stem and progenitor cell transplantation including transplanting the therapeutic composition to subjects in need of hematopoietic system reconstitution.
US09452182B2
Methods for treating a subject determined to have a cancer comprising a heterozygous inactivation of a housekeeping gene (or a homozygous deletion of a functionally redundant housekeeping gene) by treating the subject with an inhibitor of the gene. For example, a subject having a cancer with an ENO gene deletion can be treated with a glycolysis inhibitor, such as an enolase inhibitor. In some aspects, a subject having a cancer with an ARS gene deletion can be treated with an ARS inhibitor.
US09452171B2
The present invention relates to methods of treatment of clinical disorders associated with protein aggregation comprising administering, to a subject, an effective amount of an anti-protein aggregate (“APA”) compound selected from the group consisting of pimozide, fluphenazine (e.g., fluphenazine hydrochloride), tamoxifen (e.g., tamoxifen citrate), taxol, cantharidin, cantharidic acid, salts thereof and their structurally related compounds. It is based, at least in part, on the discovery that each of the aforelisted compounds were able to promote degradation of aggregated ATZ protein in a Caenorhabditis elegans model system. According to the invention, treatment with one or more of these APA compounds may be used to ameliorate the symptoms and signs of AT deficiency as well as other disorders marked by protein aggregation, including, but not limited to, Alzheimer's Disease, Parkinson's Disease, and Huntington's Disease.
US09452168B2
The invention provides compounds of formula (I), and pharmaceutically and agriculturally acceptable salts thereof; wherein: R1, R2, R3, R4, R5, R6, A1, L1 and n are as defined herein. These compounds and their pharmaceutically acceptable salts are useful in prevention or treatment of a fungal disease. Compounds of formula (I), and agriculturally acceptable salts thereof, may also be used as agricultural fungicides.
US09452159B2
A method or composition including 6-aminopyridin-3-ol derivatives or pharmaceutically acceptable salts thereof for treating a disease caused by angiogenesis, the 6-aminopyridin-3-ol derivatives represented by Formula 1 or the pharmaceutically acceptable salts thereof have excellent neoangiogenesis inhibition effects in the chorioallantoic membrane model, and are suitable for use as a drug for the treatment of disease caused by angiogenesis.
US09452157B2
The present invention relates to rifaximin compositions comprising amino acids, characterized in that they increase rifaximin solubility in aqueous solutions and are useful in the treatment of disease wherein amino acids and rifaximin are efficacious. The present invention also relates to pharmaceutical compositions comprising rifaximin or one of the pharmaceutically acceptable salts thereof and one or more amino acid(s), wherein the molar ratio between the amino acid(s) and rifaximin is from 1:1 to 10:1, together with pharmaceutically acceptable excipients. The present invention further relates to rifaximin crystals obtained by dissolving rifaximin and amino acids in solutions formed by ethanol/water and evaporating the solution.
US09452154B2
This invention relates to combinations of therapeutic molecules useful for treating hepatitis C virus infection. The present invention relates to methods, uses, dosing regimens, and compositions.
US09452151B2
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
US09452147B2
Compositions, formulations, methods, and systems for treating regional fat deposits comprise contacting a targeted fat deposit with a composition comprising long acting beta-2 adrenergic receptor agonist and a compound that reduces desensitization of the target tissue to the long acting beta-2 adrenergic receptor agonist, for example, glucocorticosteroids and/or ketotifen. Embodiments of the composition are administered, for example, by injection, and/or transdermally.
US09452145B2
A drug-containing patch allows transdermal administration of a drug. The patch features a hydrophobic reservoir containing the drug, where the reservoir has a first surface and a second surface. A drug-impermeable backing overlies the first surface of the reservoir. A release sheet may overlie the second surface of the reservoir. The hydrophobic reservoir contains a drug and a hydrophobic matrix, where the hydrophobic matrix includes a hydrophobic filler in an amount which is effective to adsorb said drug; and a mixture of polyisobutylene and mineral oil. The hydrophobic matrix may contain hydrophobic colloidal silica as the hydrophobic filler. The hydrophobic reservoir layer may serve as a skin-contacting adhesive layer. Alternatively, a release-controlling adhesive layer may serve as the skin-contacting adhesive layer. The release-controlling adhesive layer may contain hydrophobic colloidal silica and a mixture of polyisobutylene and mineral oil.
US09452143B2
The invention relates to matrix and layer compositions comprising a first polymer. The matrix and layer compositions are useful in the delivery of bioactives. In particular, the matrices and layers may have advantageous properties including mechanical properties and protection of bioactives and may also provide for pH-dependent release of a bioactive.
US09452138B2
Formulations and methods are disclosed which provide controlled, sustained release of a biologic therapeutic to a space within the body. More specifically, formulations comprising a plurality of hydrophilic polymer strands, and methods of forming and administering such formulations, are disclosed. In some embodiments, the formulations exhibit a burst release, an initial release, a triphasic release, and release over thirty to ninety days of the biologic therapeutic. In some embodiments, the formulations exhibit reversible precipitation of the biologic therapeutic into precipitates having a diameter of about 50 nm to about 10 μm.
US09452136B2
The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and nucleic acids. The reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of nucleic acids to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.
US09452126B2
Pharmaceutical/cosmetic compositions containing a dermatologically effective amount of hyaluronic acid, at least one retinoid and/or salt and/or derivative thereof, at least one oligosaccharide and at least one inhibitor of hyaluronic acid degradation, formulated into a physiologically acceptable medium therefor, are useful for the treatment of wrinkles, fine lines, fibroblast depletions and scars.
US09452123B2
A method for oral health treatment of a subject using a composition having an anti-oxidant enzyme, an anti-inflammatory agent, and a pharmaceutically acceptable buffer. In certain embodiments, the compositions are administered to the subjection in conjunction with teeth whitening, oral surgery, oral pathology treatment, endodontic therapy, periodontal therapy, dental restoration, preventative tooth cleaning, or subsequent to a pro-oxidant.
US09452122B2
The present invention provides a composition for improving skin conditions, containing the extracellular domain of human bone morphogenetic protein receptor 1a as an active ingredient. The present invention contains the extracellular domain of human bone morphogenetic protein receptor 1a as an active ingredient inside a nanoliposome comprising hydrogenated lecithin as a constituent component, and the particle size is 50-250 nm. The composition of the present invention reduces wrinkles and alleviates atopic dermatitis. In addition, the present invention provides a method for improving skin conditions, comprising the step of administering a composition containing the extracellular domain of human bone morphogenetic protein receptor 1a as an active ingredient to a subject.
US09452119B2
Provided are compounds and compositions thereof that are useful as antioxidants in personal care formulations. The compounds are of the formula I: wherein R, R1, R2, R3, R4, R5 and R6 are as defined herein.
US09452115B2
The present invention relates to a shield for radiation attenuation. The shield includes a carrier suitable for topical application on human tissue, such as skin. The carrier includes an active ingredient that is homogenously dispersed throughout the carrier. The active ingredient includes an element suitable for attenuating radiation and having a high atomic number.
US09452112B2
A self-etching and self-adhesive dental restorative composition is described herein. The composition includes a polymerizable compound having at least one phosphorus containing acidic group, a polymerizable compound having at least one carboxylic acid group, and a copolymerizable multi-functional (meth)acrylate monomers. Compositions described herein demonstrate adhesion to dentin and enamel and are useful as a cavity filler, dental pit and fissure sealants, and restoratives.
US09452108B2
A method of using a device for encouraging adherence to a medication schedule and proper administration technique includes placing the device on a surface. The device includes a body, a timer associated with the body for measuring and displaying an elapsed time since an immediately prior medication dose was administered; and a button on the body that, when depressed relative to the body, resets the timer. The button is sized and shaped for accommodating a medication container used to store or activate the medication. The button and the body are configured for cooperating with the medication container for facilitating mixing of the medication. The method further includes engaging the medication container with the button and resetting the timer.
US09452105B2
The invention relates to a dosing dispenser having a dosing piston, for dosing formulations of a drug or nutritional supplement in the form of a free-flowing bulk material having a particle diameter in the range of 100-1000 μm.
US09452103B1
A breast nipple stimulation device, for stimulating a breast nipple for nursing features a handle that tapers from a larger diameter to a smaller diameter. The device features a stimulation tip located on a handle first end tip that projects out and away from the handle first end tip. The device features a first handle arch and a second handle arch that are located on a single side of the handle. The second handle arch is larger than the first handle arch.
US09452101B2
Provided is a comfortable and discrete device wearable by a patient to restore balance and gait. The device re-establishes the sensorimotor loop by providing the patient with a secondary signal to healthy nerves around the knee to alert the patient that the patient's heel has just struck the ground. In this regard, the device monitors the patient's leg movements to detect when the patient's heel strikes the ground and sends the secondary signal, i.e., vibrotactile stimulation, in response to the detected heel strike. The central nervous system incorporates the new signal and the motor system responds as if there is not loss of sensation in the foot and returns to its normal gait.
US09452100B2
A pelvic-abdominal support garment including a waist encircling band having shorts secured to the lower edge thereof, the shorts having a receptacle for receiving an ice pack, and a strap member secured at one end thereof to the back of said waist encircling band and the other end thereof attachable to the front of the waist encircling band after passing under the crotch region of the shorts to apply pressure to the crotch area of the wearer.
US09452095B2
Absorbent core for disposable absorbent articles, particularly for the absorption of menses or blood. The absorbent core has at least two layers. A first layer having cellulose fibers that is substantially free of absorbent gelling materials; and a second layer having fibers and an absorbent gelling material and is substantially free of cellulose fibers.
US09452089B2
Absorbent members and methods of making the same are disclosed. In one embodiment, the absorbent member is a unitary absorbent fibrous web having a density profile through its thickness. In one embodiment, the density profile is relatively centered through the thickness of the web and the maximum density of the web is located between about 35% and about 65% of the distance through the thickness of the web. In one embodiment, the method involves subjecting a precursor web to at least one cycle (or pass) through a mechanical deformation process. Typically, the method involves subjecting the precursor web to multiples cycles (or passes) through a mechanical deformation process.
US09452083B2
A bioresorbable drug eluting intravitreal implant system includes a syringe with a chamber containing a medicinal drug. A balloon is releasably secured to a needle where the needle has a central section chamber in fluid communication with a chamber in the syringe. The needle central section has an opening formed through a wall for transporting the medicinal drug to the interior of the balloon subsequent to insertion of the needle through the sclera of a patient's eye.
US09452070B2
A vascular device is provided that includes a mesh structure formed of a plurality of spaced members. The structure has (i) a first, collapsed configuration, (ii) a second, expanded configuration, and (iii) a density of the plurality of members. The vascular device further includes an elastic member disposed along a region of the structure, the region having a proximal end and a distal end. The Elastic member is configured to increase the density within the region by drawing at least one of the proximal and distal ends of the region toward the other of the proximal and distal ends when the structure is in the second configuration.
US09452069B2
A reconfigurable delivery system is disclosed having a multi-lumen delivery catheter configuration that permits the delivery and staged release of a self-expanding main vessel stent-graft and a delivery sheath configuration that permits the introduction of various medical devices for the delivery and implantation of various branch vessel stent-grafts that are to be mated with the main vessel stent-graft. A method is disclosed wherein the delivery system is first used in the multi-lumen delivery catheter configuration to deliver and release a main vessel stent-graft that is configured for placement in the abdominal aorta for treatment of short-neck infrarenal, juxtarenal, and/or suprarenal aneurysms and then used in the delivery sheath configuration to facilitate the delivery of branch vessel stent-grafts that are configured to extend from the main vessel stent-graft into a respective renal artery.
US09452067B2
A mandrel for supporting a stent and rollers for pressing a radiopaque marker into a stent are disclosed. The mandrel can have a forward portion for carrying the stent and a rear portion for urging the stent forward portion into a gap between the rollers. The mandrel may be pushed or pulled into the gap, which is sized to allow the rollers to press the marker into engagement with the stent. Prior to moving the mandrel into the gap, the marker may be placed on a surface of the stent or partially inside a recess in the stent. Several markers can be efficiently and uniformly pressed onto the stent by moving the mandrel into the gap in one continuous movement in an axial or lateral direction. Markers can also be pressed onto the stent by placing the stent in the gap and rotating the stent about its central axis.
US09452066B2
A transcutaneous prosthesis which includes a first component shaped for implantation into a bone, a second component intended for location between the bone and the skin, the second component having a surface treatment for stimulation of fibroblastic cell proliferation and attachment of epithelial cells, and a third component intended for location exterior to the skin surface having a low surface energy which deters bacterial adhesion.
US09452060B2
An implant stabilizes two adjacent bones of a joint, while enabling a natural kinematic relative movement of the bones. Support components are connected to each bone of the joint, and a flexible core is interposed between them. The core and at least one of the support components are provided with a smooth sliding surface upon which the core and support component may slide relative to each other, enabling a corresponding movement of the bones. The surfaces may have a mating curvature, to mimic a natural movement of the joint. The core is resilient, and may bend or compress, enabling the bones to move towards each other, and or to bend relative to each other.
US09452052B2
An artificial knee joint (1) is described and comprises a femoral component (10) and a tibial component (30), for attachment to the femur (2) and tibia (3) of a patient (4) respectively. The femoral component (10) comprises a lateral condyle (11) and a medial condyle (12) which extend from the posterior (13) to the anterior (14) of the femoral component (10). A femoral gap (15) is provided between the lateral (11) and medial (12) condyles extending from the posterior (13) toward the anterior (14) of the femoral component (10). The lateral (11) and medial (12) condyles are joined at the anterior (13) of the femoral component (10) to form a patella tracking path or bearing surface (16) which is located at and forms the anterior end of the gap (17). A femoral cam (18) is provided bridging the posterior ends of both the lateral (11) and medial (12) condyles, and forms a posterior end of the gap (19), wherein the femoral cam (18) is structured to have the shape of a section of a ring (20). The tibial component (30) is provided with two approximately symmetric articulation bearing surfaces (31, 32) either side of a central post (33), wherein the articulation bearing surfaces (31, 32) are for receiving the lateral (11) and medial (12) condyles of the femoral component (10), and the post (33) is shaped such that it will fit within the femoral gap (15).
US09452050B2
The present disclosure relates to a method incorporating computer-implemented steps, a computing device, and a computer readable storage medium, for developing manufacturing parameters for manufacturing an orthopaedic implant. The method comprises the computer-implemented steps of being responsive to patient specific information data for deriving patient data, where the patient specific information data is indicative of one or more dynamic characteristics, being responsive to the patient data for calculating design data for the orthopaedic implant, and developing the manufacturing parameters for manufacturing the orthopaedic implant according to the design data.
US09452041B2
In a cardiac double stent having an outer netting over an inner scaffolding, a limiting ridge for defining advancement of the outer netting over the inner scaffolding, and locking clips integrated in the outer netting for engaging the scaffolding at the insertion limit, assures definite placement and avoids shifting or movement from retracting of the delivery device. The delivery device further includes restricting ridges limiting advancement of the inner netting to overlie the inner scaffolding a substantially equal portion on the proximate and distal ends of a guide wire such that balloon catheter expands first at the overlying portion outside the inner scaffolding to sealably contact the lumen wall on each side of the scaffolding to prevent contamination.
US09452040B2
Embolic protection filtering devices and methods for making and using the same. An example embolic protection filter device may include an elongate shaft. A filter may be coupled to the shaft. The filter may include a filter frame and a filter membrane having a plurality of apertures formed therein attached to the filter frame. The filter may be configured to shift between a first collapsed configuration and a second expanded configuration. The apertures may have a first shape when the filter is in the first configuration and a second shape when the filter is in the second configuration.
US09452039B2
A filter, configured to be disposed within a body lumen, such as within the vasculature. The filter may include a plurality of struts, configured to interact with the body lumen wall in order to stabilize the position of the filter and to create a filtering structure. Each strut may have two or more apexes configured to contact the body lumen wall. In some embodiments the filter may be integrally formed form a single tube of material.
US09452032B2
Soft tissue preservation temporary (shell) immediate-implant abutment with biological active surface
An immediate dental implant shell has outer, multiple zones for engaging a soft tissue socket left immediately after tooth extraction from a bone socket. The zones have combinations of different biologic agents, macro- or micro-geometric, or micro- or macro-morphology irregularities to better engage gingival sulcus, junctional epithelium and dento-gingival fiber zones of the soft tissue socket. The shell may also have various guide markings and projections to aide drilling of the implant hole in the bone socket. A dental implant is placed in the drilled implant hole before or after the shell has been placed in the soft tissue socket, and has an axis that is independent of the shell axis so the shell and implant both sit in optimum positions in their respective soft and bone sockets.
US09452028B1
An externally-threaded, endosseous dental implant includes an elongated body that is straight or tapered, and that includes external, distal regular threads, external micro-threads proximal to the regular threads, and external micro-grooves proximal to the micro-threads, with an internal passage in the body of the implant, the passage including internal threads, or internal multi-sided adaptor-engaging surfaces, or both.
US09452025B2
A medical instrument holder and method of holding a medical instrument is provided. The medical instrument holder includes a first substantially planar structure having at least a first aperture positioned therein. A second substantially planar structure is positioned approximately parallel to the first substantially planar structure. The second substantially planar structure has at least a second aperture positioned therein, wherein the second aperture is flexible. At least one holding structure is connected between the first substantially planar structure and the second substantially planar structure.
US09452019B2
A robotic assembly is configured to support, insert, retract, and actuate a surgical instrument mounted to the robotic assembly. The robotic assembly includes an instrument holder base member, a motor housing moveably mounted to the instrument holder base member, a carriage drive mechanism operable to translate the motor housing along the instrument holder base member, a plurality of drive motors, and a plurality of output drive couplings driven by the drive motors. One or more of the drive motors includes one or more magnetic flux shields to inhibit magnetic interference with an adjacent drive motor and/or with an adjacent motor orientation sensor.
US09452009B2
An electrosurgical device: forceps having: a first working arm, a second working arm, wherein the electrosurgical device has a first electrosurgical configuration where the first working arm and the second working arm are in an opposed position so that the forceps deliver a first therapy current that flows between the first working arm and the second working arm; and wherein the electrosurgical device has a second electrosurgical configuration when the first working arm, the second working arm, or both are repositionable relative to each other so that the first working arm is extended with respect to the second working arm or vice versa and a second therapy current is delivered from the first working arm to a remote electrode.
US09452006B2
A polyaxial bone anchoring device includes a bone anchoring element having a shank and a head, a receiving part including a rod receiving portion, and a head receiving portion having a first end and an open second end with a bounding edge, wherein the head receiving portion is configured to be rotatably connected to the rod receiving portion and is flexible for introduction and clamping of the head, and a locking ring configured to be mounted around the head receiving portion, wherein the head is insertable into the head receiving portion from the second end, is pivotable in the head receiving portion at a larger maximum pivot angle relative to the receiving part at a first location of the bounding edge, and can be locked at an angle relative to the receiving part by compressing the head receiving portion with the locking ring.
US09452000B2
A rod reducer apparatus is disclosed and includes a housing, an anvil coupled to a shaft, a plurality of arm members, and a button. The housing has an opening extending therethrough for receiving the shaft. The anvil is coupled to one end of the shaft. The button is slidably disposed in the housing and transitionable between first and second positions. The button is engageable with the shaft such that rotation of the shaft is translated into linear movement of the anvil.
US09451983B2
A cannula with a proximal end, a distal end and a lumen penetrating from the proximal end to the distal end. The cannula includes a shaft portion including a rear end and a front end, a tip portion coaxially extending from the front end of the shaft portion to the distal end of the cannula, and a cutting edge. A coupling portion, which is suitable for being connected to a surgical tool or instrument, is terminally arranged towards the proximal end of the cannula and extends to the rear end of the shaft portion. A removable obturator is insertable in the lumen. The obturator seals the lumen at the distal end of the cannula. A method for improved fracture fixation using the cannula, a method for intraoperative surgical decision making using the cannula and a method for irrigation of bone tissue and subsequent injection of bone cement using the cannula.
US09451981B2
A surgical sheath for use in endoscopic trans-nasal or intra-ocular surgery has first and second attachment fittings on opposite side of a conical section used for attaching individual sheaths to form a sheath pair. The sheaths of the pair can mutually support each other during surgery, to better resist inadvertent displacement of the sheaths. After the sheaths are positioned, the conical sections of the sheaths may be attached together using clips, pins, belts or other techniques. The sheaths reduce collateral trauma to the tissues in the surgical pathway.
US09451978B2
An expandable cage is expanded within a narrowed region of a blood vessel. The expandable cage has openings therein so that plaque protrudes through the openings when the cage is expanded. A material removing element passes within the cage to remove the plaque extending into the openings. The openings are preferably formed by integrally formed elements which provide a smooth internal surface. The material removing element passes along the smooth internal surface when removing the plaque. A collection bag is coupled to the material removing element to capture the material which has been removed.
US09451970B2
Disclosed herein is a method of defining a mating surface in a first side of an arthroplasty jig. The mating surface is configured to matingly receive and contact a corresponding patient surface including at least one of a bone surface and a cartilage surface. The first side is oriented towards the patient surface when the mating surface matingly receives and contacts the patient surface. The method may include: a) identifying a contour line associated with the patient surface as represented in a medical image; b) evaluating via an algorithm the adequacy of the contour line for defining a portion of the mating surface associated with the contour line; c) modifying the contour line if the contour line is deemed inadequate; and d) employing the modified contour line to define the portion of the mating surface associated with the contour line.
US09451967B2
A device for fastening tissue includes (a) a shaft extending longitudinally from a distal end insertable into a body to a proximal end attached to a controller which remains outside of the body, the shaft including a lumen extending therethrough and an opening extending through a wall of a distal portion thereof to open the lumen to an exterior of the shaft; (b) a first roller housed within the lumen adjacent to a first longitudinal edge of the opening such that a rotation of the first roller grasps and draws tissue from the body into the lumen in combination; and (c) a fastening element housed within the lumen adjacent to the opening and movable from a tissue receiving configuration to a tissue gripping configuration.
US09451966B2
A hand-operable surgical clip applicator (10) including a barrel (12) having a first end (14) and a second end (16), the second end formed to accommodate a surgical clip, a crimping lever (20) pivotally connected at the second end of the barrel, and a trigger (28) co-located with the barrel, the trigger being operable to pivot the crimping lever, the pivoting movement of the crimping lever causing the surgical clip to be urged from an open position to a closed position, wherein the trigger has an operating portion on either side of the barrel.
US09451965B2
A method for reducing or stopping flow through a tubular structure of a patient can include positioning an elongate member within a lumen of the tubular structure. The elongate member can be arranged to form a frame having a distal opening and a proximal opening. The elongate member can substantially reduce or totally obstruct, with a flow reducing member coupled to the frame, flow of at least one of emboli and fluid flowing through the lumen. The flow reducing member can comprise a one-way valve that moves in response to fluid flow to substantially prevent distal flow through the distal opening and to allow proximal flow through the distal opening.
US09451961B2
Methods and systems are provided for tissue stabilization. Some aspects include a carrier member having a length, width, and thickness, wherein the length and width are each at least two times greater than the thickness; attachment members extending from the carrier member and that engage connective tissue; and stabilizing members, each of which can couple a respective attachment member to the carrier member and is substantially positionally fixed relative to the carrier member.
US09451960B2
Devices and methods for gastrointestinal bypass are described. A gastrointestinal bypass device includes a gastrointestinal cuff and a gastrointestinal sleeve. The cuff may be configured to be attached in the esophagus, and may be sufficiently flexible to expand and collapse to conform with the inside of the esophagus to allow the esophagus to function substantially normally. The sleeve is configured to be coupled to the cuff, and may be made of a material that is floppy or flaccid but does not substantially expand radially.
US09451957B2
A bone staple extrusion instruments used for fixation of bone and soft tissue of the musculoskeletal system and the methods for their use and manufacture. The bone staple extrusion instruments are used for insertion of staples into bones, which staples change shape through their metallurgic properties and the release from the bone staple extrusion instruments. In some embodiments, the bone staples pull together and compress bone once released from the bone staple extrusion instruments. In other embodiments, the staples push outward to place the bones in tension once released from the bone staple extrusion instrument.
US09451956B2
A staple housing includes an array of staples each in a staple delivery position or “ready position” ready to be fired into target tissue. A staple driver is advanceable to drive the ready position staples from the staple head into the tissue using staple pushers. During use, the staples in the ready positions are simultaneously fired into the target tissue using the staple pushers, forming an array of staples in the target tissue. After the array has been fired, one or more feed mechanisms within the staple housing advance a second group of staples from one or more staple storage locations into the ready positions in preparation for firing of the second group of staples.
US09451941B2
A surgical tissue connector system for moving a first internal body tissue to a position away from a second internal body tissue and then holding the first internal body tissue in the position. Tissue connectors are secured to cords such that the length of cord between the tissue connectors can be easily adjusted in a laparoscopic work space.
US09451939B2
The invention relates to a sealing device for repair of cardiac and vascular defects or tissue opening such as a patent foramen ovale (PFO) or shunt in the heart, the vascular system, etc. and particularly provides an occluder device and trans-catheter occluder delivery system. The sealing device would have improved conformity to heart anatomy and be easily deployed, repositioned, and retrieved at the opening site.
US09451933B2
Adjustment of operation of an ultrasound imaging system may be based at least in part on one or more characteristics represented in ultrasound return signals from two or more sample volumes. Adjustment may include adjusting a principal sample volume location or selecting a new principal sample volume. For example, a location of a principal sample volume may be adjusted or new principal sample volume selected so as to remain focused on an identified region of interest or to maintain the principal sample volume relative to some structure or reference. The principal sample volume may be maintained in the center or along a centerline of an artery or other structure, as the transducer array is moved along the artery or structure.
US09451930B2
The average velocity of a tissue is calculated for each frame in accordance with compression/release, and a reference waveform is generated by using the calculated velocity. A time phase in which the average velocity becomes 0 is specified by the reference waveform. In strain computation, time integration is performed for strain computation in a compression period or a release period with reference to the specified stationary time phase. This can properly and automatically visualize how the contraction of the tissue is accumulated from the start of compression or the contraction of the tissue becomes maximum in a compression end time phase in a compression period and how the tissue expands from the start of release or the expansion of the tissue becomes maximum in a release end time phase in a release time phase.
US09451929B2
A catheter assembly for an intravascular ultrasound system includes a catheter and an imaging core. The catheter has a longitudinal length, a distal end, and a proximal end. The catheter includes a sealable lumen extending along the longitudinal length of the catheter from the proximal end to the distal end, and a movable plunger or a movable seal in fluid communication with the lumen. The movable plunger or the movable seal provides a gas-tight seal. The movable plunger or the movable seal is configured and arranged for adjusting to changes in volume of the lumen when the lumen is filled with an acoustically-favorable medium and sealed. The imaging core is configured and arranged for inserting into the sealable lumen and for coupling to a control module.
US09451922B2
A radiation protection arrangement, in particular for attachment to at least one support rail which is preferably attached with a fastening device to one or more sides of the treatment table, comprising a fastening device at the at least one lamella which comprises a material for protection against radiation, preferably X-ray radiation, is preferably pivotably mounted, wherein the fastening device comprises a holder which can be attached to the support rail, wherein the holder comprises: at least one pivotably mounted handle, the handle having a free end and an end on which the handle is pivotably mounted, a locking mechanism suitable for locking the holder on the support rail, wherein the locking mechanism can be actuated by a pivotal movement of the at least one handle that is pivotably mounted on the holder.The invention further relates to a radiation protection arrangement, in particular for attachment to at least one support rail which is preferably attached to one or more sides of the treatment table, comprising a holder which can be attached to the support rail and at least one detachable lamella which can be attached to the holder at various positions, the radiation protection arrangement being preferably combinable with one of the preceding radiation protection arrangements.
US09451917B2
The present invention is a dual resonant breast coil design for combined sodium and proton breast MRI with increased SNR at 3T when compared to a coil with a single proton and sodium channel. The coil consists of a 7-channel sodium receive phased array, a large sodium transmit coil, and a 4-channel hydrogen transceive array. An interleaved overlapping coil layout is used to reduce coupling between sodium and proton coil elements. The new composite array coil demonstrates a 2-5× improvement in SNR for sodium imaging when compared to a simple single-loop dual resonant design.
US09451915B1
The present disclosure describes example systems and methods for identifying an indication of an injury of a user of a wearable computing device. The systems and methods may be directed to determining that an acceleration experienced by the wearable computing device exceeds a threshold value. In response, the wearable computing device may perform a diagnostic procedure in order to identify an indication of an injury experienced by the user of the wearable computing device. The diagnostic procedure may include one or more of an eye response test, a verbal response test, a motor response test, and a visual diagnostic test.
US09451911B1
A test model for simulating one or more physiological parameters is provided. In one example, the test model includes a model layer having a test surface, a shaft rotatably disposed within the model layer and at least first and second contrast segments circumferentially disposed on the shaft. The model layer models at least one optical property of human skin, such as transmissivity of at least a particular wavelength of light transmitted into the model layer. The first and second contrast segments have contrasting optical properties with regard to at least the particular wavelength of light, such as reflectance. Rotation of the shaft causes different contrast segments to face the test surface of the model layer at different times.
US09451906B2
Methods, systems and computer readable storage medium for retrieving mental images of faces from the human brain. An exemplary embodiment includes a method for retrieving mental images of faces from a human brain, the method including generating an image on a screen, measuring brain activity data from a brain scanner, varying characteristics of the image on the screen, detecting changes in the brain activity data measured from the brain scanner, and generating a final image on the screen, the final image being related to a subjectively described mental image.
US09451900B2
The present invention relates to an arrangement (10) for heating of a magnetic material (100) located in the center region of an inscribed sphere within a region of action, which arrangement comprises: —selection means (210) for generating a magnetic selection field (211) having a pattern in space of its magnetic field strength such that a first sub-zone (301) having a low magnetic field strength and a second sub-zone (302) having a higher magnetic field strength are formed in the region of action (300), —drive means (220) for changing the position in space of the two sub-zones (301, 302) in the region of action (300) by means of a magnetic drive field (221) so that the magnetization of the magnetic material (100) changes locally, and —control means (76) for controlling the drive means (220) to change the position in space of the first sub-zone (301) along a sequence of locations around said inscribed sphere for so long and with such a frequency that the center region of said inscribed sphere is heated.
US09451896B2
Compact, single-handedly manipulable, cardiography devices, structured for personal use in two, selectively different, functional-cardiography styles, enabling, respectively, one or both of (a) non-acoustic, and (b) acoustic, cardiography, such use involving, as appropriate to the particular functional-cardiography style to be implemented, the collecting and recording of personal cardiography-relevant data—ECG only in a non-acoustic case, and both ECG and heart-sound together in an acoustic case—suitable for subsequent data-analysis processing, and associated cardiovascular diagnosis. Two, representative device overall configurations are illustrated, including (1) a stylus pen-like shape, and (2) a finger-mountable ring-like shape. Collected-data analysis processing, and associated cardiovascular diagnosis, may be performed by device-included electronic information-handling structure, or may, via operation of such electronic structure, be communicated appropriately “outwardly” from the relevant device for external processing and analysis.
US09451893B2
Self-correlation enhancements and implementations are described. In particular, certain examples demonstrate the analytical tools to reduce the computational burden of generating a self-correlation function within an implantable medical device. Peak selector and tracking analysis are also included as secondary elements for identifying and generating confidence in rate estimates based on the self-correlation function. The approach may enable an alternative calculation of cardiac rate in an implantable medical device as a stand-alone rate detector or as a double-check of other rate calculations.
US09451888B1
An apparatus and method for determining stroke volume by bioimpedance from a person that includes two or more spaced apart alternating current flow electrodes positionable on a person's forearm, two or more spaced apart voltage sensing electrodes positionable on the person's forearm and between the alternating current flow electrodes, an alternating current source providing an alternating current to the current flow electrodes, a voltmeter configured to generate a voltage signal from a voltage sensed by the voltage sensing electrodes, and a processing unit configured to determine a stroke volume (SV) using the voltage signal and at least one of two equations that include, among other terms, the person's weight, a peak time rate of change of a transradioulnar impedance pulse variation (dZ/dtmax), a transradioulnar quasi-static base impedance (Z0), a systolic flow time (TSF), and a volume conductor (Vc).
US09451886B2
A probabilistic digital signal processor using data from multiple instruments is described. In one example, an analyzer is configured to: receive discrete first and second input data, related to a first and second sub-system of the system, from a first and second instrument, respectively. A system processor is used to fuse the first and second input data into fused data. The system processor optionally includes: (1) a probabilistic processor configured to convert the fused data into at least two probability distribution functions and (2) a dynamic state-space model, the dynamic state-space model including at least one probabilistic model configured to operate on the at least two probability distribution functions. The system processor iteratively circulates the at least two probability distribution functions in the dynamic state-space model in synchronization with receipt of updated input data, processes the probability distribution functions, and generates an output related to the state of the system.
US09451878B2
This invention is directed towards a medical image processing apparatus capable of providing effective information on glaucoma by integrating the tomographic image of the retina obtained by an optical coherence tomograph (OCT: Optical Coherence Tomography) and visual function information obtained by a perimeter. The medical image processing apparatus associates visual field measurement results with a fundus camera image (S420). The medical image processing apparatus registers, on the fundus camera image associated with the visual field measurement results, a layer thickness distribution which is obtained from an OCT tomographic image and indicates the thickness of the nerve fiber layer in the retina layer of an eye to be examined (S440). After that, the medical image processing apparatus presents information indicating glaucoma of the eye to be examined, based on the layer thickness distribution registered on the fundus camera image, and the visual field measurement results (S470).
US09451869B2
A washing machine with a direct drive system including a tub, a drum rotatably mounted inside the tub, a shaft connected to the drum at a first end for transmission of a driving force of a direct drive motor, a coaxial support connected to a rear portion of the tub and having a first seat for a first bearing supporting a second end of the shaft opposite the drum, a stator secured to the coaxial support and having a plurality of magnetic cores, a rotor including permanent magnets and connected to the shaft, and a second bearing for supporting the shaft between the second end and the first end. The tub is made of polymeric material in which a second seat for said second bearing is co-molded.
US09451867B2
A dishwasher comprising a tub at least partially defining a treating chamber in which liquid may be sprayed from at least one sprayer for the treating of dishes within the treating chamber. A liquid recirculation system may be provided for recirculating the sprayed liquid back to the at least one sprayer. An ozone generator may be provided in communication with the treating chamber to supply ozone to the treating chamber.
US09451860B2
A cyclone separator is provided. The cyclone separator includes: a cyclone, an end cover of the cyclone separator, a filter and a wind guiding cylinder. The cyclone has an open end and a bottom wall defining an inlet of the cyclone separator therein. The end cover of the cyclone separator is disposed over the cyclone and defines an outlet of the cyclone separator therein. The filter has an upper end communicating with the outlet of the cyclone separator and a lower end extended into the cyclone. The wind guiding cylinder has a lower end communicating with the inlet of the cyclone separator, a closed upper end and a side wall defining a vent communicating with the cyclone.
US09451852B2
An upright surface cleaning apparatus comprises an air flow path extending from a dirty air inlet to a clean air outlet, a surface cleaning head having the dirty air inlet, a support structure moveably mounted to the surface cleaning head, the support structure comprising a cleaning unit The cleaning unit comprises a suction motor and an air treatment member positioned in the air flow path The cleaning unit is removably mountable wherein the cleaning unit is retained on the support structure when in a storage position under the influence of gravity.
US09451843B2
A device for assisting the introduction of a body part into a tightly-fitting garment or footwear, comprising an elongate flexible laminar element of low friction material having load spreading means at one end of the element, operable, when a force is applied thereto, to spread the force across substantially the entire width of the laminar element, and handle means for manually gripping the load spreading means to assist in effecting withdrawal of the said laminar element from the interspace between a body part and a garment or footwear into which it has been introduced.
US09451836B2
A merchandising security system includes a support adapted to be secured to a first associated merchandising structure and at least one product barrier movably mounted to the support. The at least one product barrier extends away from the support so as to approach a second associated merchandising structure spaced from the first associated merchandising structure. The product barrier is at least one of slidably mounted in relation to the support and pivotably mounted in relation to the support, wherein the product barrier includes first and second members which cooperate to retard a forward movement of an associated object supported on the first associated merchandising structure. At least one of the first and second members is mounted in relation to the support via a hinge.
US09451810B2
Manufacturing of a shoe or a portion of a shoe is enhanced by automated placement of shoe parts. For example, a part-recognition system analyzes an image of a shoe part to identify the part and determine a location of the part. Once the part is identified and located, the part can be manipulated in an automated manner.
US09451804B2
An article of footwear may include an upper and a sole structure secured to the upper. The sole structure may include an outsole including ground engaging members and a reinforcement member. The reinforcement member may extend between (1) a first mounting member located in a forefoot region of the outsole and configured to connect the reinforcement member to the outsole, and (2) a second mounting member located in a heel region of the outsole and configured to connect the reinforcement member to the outsole. The first mounting member may be located adjacent to a ground engaging member in the forefoot region of the outsole and the second mounting member is located adjacent to a ground engaging member in the heel region of the outsole.
US09451798B2
The present disclosure relates to a method for configuring a passive-assist glove comprising measuring, in a first measuring operation, force associated with receiving an object into a stress zone at a palmar surface of the hand, the stress zone; measuring, in a second measuring operation, force associated with receiving an object into a dexterity zone at a palmar surface of the hand, the dexterity zone; providing a plurality of palm sections for the glove; and arranging the plurality of palm sections being in the glove based on results of the measuring operation and to allow manipulation of the palm and the at least one of the multiple fingers to receive the object during use of the glove.
US09451781B2
The invention provides a novel strain of cadmium-removing Lactobacillus plantarum bacterium, CCFM8610, which has a good tolerance to acidic environments. Lactobacillus plantarum CCFM8610 has a good tolerance to cadmium-containing medium and can effectively bind cadmium in vitro. Animal studies have shown that it can effectively reduce tissue cadmium accumulation and facilitate fecal cadmium excretion. Lactobacillus plantarum CCFM8610 has a great potential to be used as an active ingredient in cadmium-removing pharmaceutical drugs and fermented foods.
US09451766B2
Disclosed are compositions that include treated biodiesel glycerin. The disclosed compositions may be utilized as soil-amendments for controlling pests, weeds and for enhancing growth of plants. The biodiesel glycerin utilized in the disclosed compositions may be treated by one or more steps including neutralization, heating, refluxing, condensing, and distilling.
US09451764B2
The present invention relates to compositions for pest control, more particularly insecticides, to a process for preparing them, and to the use of such formulations for sustained control of animal pests (arthropods) on various surfaces. The present invention further relates to active ingredient-wax particles in which at least one active insecticidal ingredient is dispersed in wax.
US09451763B2
An aqueous disinfectant formulation comprising at least one phenolic compound of natural origin; a surfactant sufficient to form a solution or dispersion of the essential oil in an aqueous carrier; a solvent, and sufficient water to make 100 weight percent is described herein.
US09451757B1
A novel maize variety designated X03F675 and seed, plants and plant parts thereof are produced by crossing inbred maize varieties. Methods for producing a maize plant by crossing hybrid maize variety X03F675 with another maize plant are disclosed. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X03F675 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X03F675, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X03F675. This invention further relates to methods for producing maize varieties derived from maize variety X03F675.
US09451754B2
The invention provides Brassica rapa plants and seeds thereof that are self-compatible, rapid-cycling and lack inbreeding depression. For instance, the invention provides plants and seeds of the Brassica rapa line designated B3. The invention thus relates to plants, seeds and tissue cultures of Brassica rapa plants that are self-compatible, rapid-cycling and lack inbreeding depression, such as Brassica rapa line B3, and methods to produce and propagate said plants by crossing such a Brassica rapa plant with itself, or another Brassica rapa plant. The invention further relates to seeds and plants produced by such crossing. Educational materials, such as a kit comprising said Brassica rapa plants are also provided by the invention.
US09451750B2
The invention provides seed and plants of Catharanthus hybrid ‘PAS1053044’ and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of Catharanthus hybrid ‘PAS1053044’ and the parent lines thereof, and to methods for producing a Catharanthus plant produced by crossing such plants with themselves or with another Catharanthus plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants.
US09451747B2
The invention provides seed and plants of Catharanthus hybrid ‘PAS1052940’ and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of Catharanthus hybrid ‘PAS1052940’ and the parent lines thereof, and to methods for producing a Catharanthus plant produced by crossing such plants with themselves or with another Catharanthus plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants.
US09451739B2
An agricultural undercut implement includes a frame carrying ground-engaging rolling means, a cutting disk arrangement to cut parallel slits in the ground soil, and an undercut assembly having upright cutting edges each aligned to follow a slit, and a transverse blade with a horizontal cutting edge disposed to undercut the ground soil between slits, as the frame rolls over the ground, such as when towed behind a tractor. The transverse blade is configured to sever the strip of ground soil undercut by the cutting edge, and then move the undercut soil strip up and over the blade before replacing it intact on the ground. A method of agricultural crop management includes non-terminatingly retarding the growth of a permanent cover crop by using the implement to undercut and replace intact the ground soil beneath the cover crop. Some examples include drive units configured to drive blades through pluralities of blade positions.
