This invention relates to a method for preparing thiourea-containing chrysanthemic amide compound, 1-(3-(2-chloro-3, 3, 3-trifluoro-1-propylene)-2, 2-dimethyl cyclopropane formamide)-3-substituted phenyl thiourea (shown in formula 1), and its application. The method comprises: reacting 3-(2-chloro-3, 3, 3-trifluoro-1-propylene)-2, 2-dimethyl cyclopropane formyl isothiocyanate and substituted aniline at a weight ratio of 1 :( 1.2-2.0) in acetonitrile under refluxing for 5-30 h, and performing post-treatment on the reaction solution to obtain compound in formula I. The compound has simple preparation method, and has good curative effect on Botrytis cinerea.