The present invention supplies a synthetic method of luminescence zinc selenide Nanorods, the method proceed with the following steps: a. first putting sodium borohydride and selenium powder with reaction ratio dissolved in water, and then, under the protection of inert gases they react to get the solution of sodium borohydride with the 1.5-2% weight concentration ; b. zinc ions are dissolved in accordance with the soluble salt: L-mercapto alanine: water = 100:22-37:140000-240000 weight ratio of blending, then mixing to join the thioglycolic acid or mercaptopropionic acid, adjusting pH = 9-11, and then remove the dissolved oxygen from solution by filling inert gas; c. putting the sodium borohydride solution of a procedure into the solution of b procedure, and then heating reversing, obtain a luminescent zinc selenide Nanorods Solution.