The invention discloses a hydrophobic-associated polyacrylamide of side chain grafting polycaprolactone and the preparing method thereof. The invention hydrophobic-associated polyacrylamide (I) is the copolymer of the acrylamide and side chain grafting polycaprolactone long-chain hydrophobic monomer which has a larger hydrophobic volume and can enhance the hydrophobic function of the polymer chain. It can control the content of the hydrophobic chain segment by controlling the amount of the hydrophobic monomer and the length of the grafting polycaprolactone long-chain in the hydrophobic monomer. It can obtain an expected adhesion effect by regulating the copolymer hydrophobic function with the polyacrylamide side chain association. The inventive hydrophobic-associated polyacrylamide changes the characteristics of the traditional polyacrylamide, which has a good adhesion-enhancing effect at a high temperature and high mineralization and can be widely used in petrochemical engineering field. Meanwhile, the producing method is suitable for industry production.