The invention relates to a separation technology of a mixture with cyclopentadiene and methyl cyclopentadiene as main ingredients, which pertains to the fine chemicals manufacturing technical field. A mixture with main ingredients of CPD and MCPD is firstly extracted from the mixture with cyclopentadiene and methyl cyclopentadiene as main ingredients from the top of a de-polymerization rectifying tower; the mixture with the main ingredients of CPD and MCPD then enters a CPD tower, and CPD is extracted from the top of a normal pressure rectifying tower; materials at the bottom of the CPD tower enter a dimerization reactor, and a mixture material with DMCPD as a main ingredient is acquired; the mixture material enters a MCPD tower to be rectified under reduced pressure, and the methyl cyclopentadiene is extracted from the top of the MCPD tower in the form of DMCPD. The invention adopts a de-polymerization normal reduced pressure separation method, which requires little supportive equipment investment and simple operation technique and can effectively overcome defects of the prior art, reduce product waste during the mixture separation process, improve extraction rate by one operation and reduce energy consumption, so that the cyclopentadiene and methyl cyclopentadiene of relatively high purity can be obtained.