The invention provides a preparation method of potassium titanium hexacyanoferrate adopting tiny ball-shaped silicagel as carrier, which relates to a preparation method of high specific surface potassium titanium hexacyanoferrate adopting tiny ball-shaped silicagel as carrier. The method is that fashioned porous tiny ball-shaped silicagel under the protection of nitrogen and in the condition of heating and refluxing reacts with organic solvent solution of tetrabutyl titanate. The acquired tiny ball-shaped silicagel loaded with unformed titanium dioxide is dried, dipped in hydrochloric acid solution of kalium ferrocyanatum and then reacting for 12-24h to acquire the high specific surface potassium titanium hexacyanoferrate by adopting tiny the ball-shaped silicagel as carrier. Potassium titanium hexacyanoferrate in the material has adjustable loading amount, good adsorptivity to nuclides, high specific surface, good particle sphericility and solidity, and avoids over-limit moisture resistance of bed layer caused by exclusive use of potassium titanium hexacyanoferrate particles; moreover, owing to existence of Ti-O-Si covalent bond, potassium titanium hexacyanoferrate particles and tiny ball-shaped silicagel can link closely, and do not lose easily during the waste water disposal.