The invention relates to an extrusion technology of titanium-copper composite profiles, which is implemented according to the following steps: (1) metal titanium is firstly processed into a cylinder shape according to the required size; (2) metal copper is molten and then poured into the processed titanium cylinder; (3) a copper foil clad at the outside of the titanium cylinder packages the wholetitanium cylinder, the copper foil clad at the outside can play a certain lubrication role after heating; (4) heating is carried out till more than 600 DEG C, the extrusion pressure is not less than 500 tons, the extrusion cylinder temperature is maintained at 300 to 600 DEG C, an oil-pressure extrusion machine above 500 tons is used for extrusion forming; the finishing processing is carried out according to the design requirements; the inspection is carried out; and a finished product is obtained. The extrusion technology has the advantages of simple titanium-copper composite technology and firm combination, which can also manufacture large-sized composite materials.