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发明公开
CN101302248A 高纯度替考拉宁的生产方法 有权

高纯度替考拉宁的生产方法
摘要：
本发明提供了一种高纯度替考拉宁的生产方法，所述方法包括：阶段a，对替考拉宁粗品溶液进行凝胶层析、和大孔吸附分离以得到替考拉宁粗品溶液；阶段b，将所述替考拉宁粗品溶液进行活性炭脱色、超滤、纳滤及结晶以得到高纯度替考拉宁。所述方法最大限度地提高了替考拉宁的生产效率，从而实现高纯度替考拉宁的产业化。
摘要（英）：

The invention provides a method for making high-purity teicoplanin. The method comprises the following stages that: stage a, gel chromatography and macropore fractionation by adsorption of a teicoplanin crude product solution are carried out so as to obtain a teicoplanin crude product solution; stage b, active carbon decoloring, ultrafiltration, nanofiltration and crystallization of the teicoplanin crude product solution are carried out so as to obtain high-purity teicoplanin. The method furthest increases the production efficiency of teicoplanin, thereby realizing the industrialization of high-purity teicoplanin.

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