A communication encryption and decryption method based on multi-parameter tetrachoric weighted score Fourier transform relating to communication technology field. The invention can disarrange constellation distribution and disenable non communication target to intercept and detect communication signal. The inventive method comprises that data source is modulated at transmitter by base band to deliver to encipher module which executes tetrachoric weighting score Fourier transform controlled under dynamic encryption parameter alpha, dynamic encryption vector MV and NV , and digital carrier modulation, then enciphered data is delivered to channel for transmitting after D/A conversion and up converter; data collected by down converter and A/D is delivered to decryption module for digital carrier coherent demodulation, deciphered data is obtained after tetrachoric weighting score Fourier transform controlled by dynamic deciphered parameter alpha, dynamic deciphered vector MV and NV, then base band demodulation is operated. The invention is suitable for secure communication device for existing communication fields.