Provided is a manufacturing method of pneumatic tire. A side surface of an apex rubber is exposed annularly by injection molding the annular apex rubber and opening a forming mold while retaining the annular apex rubber in an unvulcanized state. Further, a side surface of a rubber pad is exposed annularly by injection molding the annular rubber pad and opening a forming mold while retaining the annular rubber pad in an unvulcanized state. Thereafter, an integrated compound rubber member is formed by overlapping a lower mold retaining the apex rubber and a lower mold retaining the rubber pad and laminating the side surface of the apex rubber to the side surface of the rubber pad, and an unvulcanized tire is formed by laminating the compound rubber member to the carcass ply.