The invention relates to a method for producing 2-tertiary butyl-paracresol and 6-tertiary butyl-metacresol from mixed cresol, which is characterized in that the mixed cresol is taken as raw material; firstly, the mixed cresol is rectified and separated to obtain refined mixed cresol; then the refined mixed cresol is alkylated to obtain the mixture of 2-tertiary butyl-paracresol and 6-tertiary butyl-metacresol; and the mixture of 2-tertiary butyl-paracresol and 6-tertiary butyl-metacresol is further rectified; as the difference between the boiling point of 2-tertiary butyl-paracresol and the boiling point of 6-tertiary butyl-metacresol is 6 DEG C, the rectification method can be used for separating 2-tertiary butyl-paracresol from 6-tertiary butyl-metacresol to obtain a 2-tertiary butyl-paracresol product and a 6-tertiary butyl-metacresol product with high purity. The method greatly reduces the production cost.