The invention relates to a vinyl chloride gas-liquid filtration and separation device which comprises a cylinder, an air inlet pipe and an air outlet pipe, wherein, the cylinder consists of an upper cylinder element and a lower cylinder element, and the upper cylinder element and the lower cylinder element are connected by a flange; the air inlet pipe is arranged on the lower cylinder element, and the air outlet pipe is arranged on the upper cylinder element. A filter net element is arranged inside the lower cylinder element, and a waste discharge element is arranged at the bottom of the lower cylinder element. The device is arranged in an oil-injecting screw vinyl chloride compressor and used as one of the core elements of the oil-injecting screw vinyl chloride compressor, which realizes that the vinyl chloride gas without liquid water drops is injected into the oil-injecting screw vinyl chloride compressor under the prior art, thus protecting the compressor from damage. The device has the advantages of simple structure and simple manufacture, and realizing the functions of cyclone separation, gravity separation, barrage by filtration, etc.