The invention relates to a rotating dynamic multiphase pressure pump which comprises a pump body connected with a dynamic device and a sectional pump shell outside the pump body. The pump body comprises a homogenization unit, an intake unit, a pressurization unit and a diffusion unit. The homogenization unit has a buffer tank, the centre of which a polyporous separation tube is inserted in; the upper terminal of the separation tube passes through the buffer tank and the lower terminal is fixed to the intake unit. The intake unit comprises a water guiding wimble which is fixed on the pump shaft and is provided with a homogenization blade. The pressurization unit comprises at least two stages impeller and a series structure formed by interstage adjustors. The impeller is fixed on the pump shaft with a tapered wheel hub which is provided with the blade outside and the impeller rotates with the pump shaft; the interstage adjustor comprises the wheel hub which is interstitially sleeved with the pump shaft and is provided with a guide blade; outside the guide blade, a sleeve is fixed and the sleeve is fixed on the pump shell to the guide blade; therefore, the interstage adjustor can not rotate with the pump shaft. The diffusion unit comprises a diffuser and a discharge chamber. The pressure pump enables the oil-gas-water multiphase flow to pressurize without separation and realizes the economic production of the marginal oil field, nearby oil field and deepwater oil field.