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发明授权
CN101401815B 海螵蛸多糖提取物CBP-S及其用途 失效 - 权利终止

海螵蛸多糖提取物CBP-S及其用途
摘要：
本发明涉及医药技术领域，是从海螵蛸中制备的多糖提取物CBP-S及其用途。多糖提取物CBP-S的主要成分为CBP-S1和CBP-S2，其中，CBP-S1的单糖组成为：Rha:Fuc:Man:Glc:Gal:GlcN:GalN＝1:2.8:1:6.8:3.2:2.8:2.2，以β-1，4-Glc连接为主，而CBP-S2的单糖组分为：Rha:Fuc:Man:Glc:Gal:GlcN:GalN＝1:5.6:1:5.6:2.6:3.6:2.8，以β-1，4-Glc和1，3，4连接的岩藻糖为主。经动物实验，本发明海螵蛸多糖提取物CBP-S对急性胃粘膜损伤具有保护作用，因此可以制备保护胃黏膜的药物。
摘要（英）：

The invention relates to the medicine technical field, in particular to a polysaccharide extract CBP-S prepared from cuttlebone and application thereof. The polysaccharide extract CBP-S mainly comprises CBP-S1 and CBP-S2, wherein in the CBP-S1, the monosaccharide ratio of Rha to Fuc to Man to Glc to Gal to GlcN to GalN is 1 to 2.8 to 1 to 6.8 to 3.2 to 2.8 to 2.2, and the monosaccharides are mainly caontained in belt-1 and 4-Glc connections; and in the CBP-S2, the monosaccharide ratio of Rha to Fuc to Man to Glc to Gal to GlcN to GalN is 1 to 5.6 to 1 to 5.6 to 2.6 to 3.6 to 2.8, and the fucose in belt-1, 4-Glc and 1,3,4 connections are mainly adopted. In animal tests, the polysaccharide extract CBP-S has protective function on the acute gastric mucosa injury, so that the polysaccharide extract CBP-S can be used to prepare a drug for protecting gastric mucosa.

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