The invention discloses a stepper motor drive device based on a CAN bus. The stepper motor drive device comprises a central processing unit, a chopped wave constant current drive circuit, a drive control circuit and a current detection circuit, wherein the central processing unit is connected with a CAN bus interface circuit, an LED indicating circuit, an AD conversion circuit and a keyboard scanning circuit; the chopped wave constant current drive circuit is communicated with a central processor; the output of the chopped wave constant current drive circuit is connected with the drive control circuit of a stepper motor; the input of the drive control circuit is communicated with the central processor and receives an output signal of the chopped wave constant current drive circuit; the output of the drive control circuit is connected with a two-phase stepper motor; the current detection circuit receives the output signal of the drive control circuit and outputs the output signal to the chopped wave constant current drive circuit; and the output end of the current detection circuit is respectively connected with the central processor and the drive control circuit. The stepper motor drive device has the characteristics of realizing no declining of output torque along with the rise of rotational speed and having high resolution and wide application range and also has the advantages of low cost, strong antijamming capacity, abundant selectable resource and good technology and competitiveness.