The invention discloses a preparation method for a thermoplastic matrix super-hydrophobic membrane. A pressure sintering method is adopted to press mixed powder of micro-sized powder particles and nanometer-sized powder particles on a super-hydrophobic layer into surface of the thermoplastic membrane matrix. The operation is simple and the super-hydrophobic layer consists of the micro-sized powder particles and nanometer-sized powder particles which are arranged alternatively and are embedded in the membrane matrix to form micro-sized convex and nanometer-sized convex. The manufactured super-hydrophobic surface has relatively high intensity and relatively low manufacturing cost; and the super-hydrophobic structure can be manufactured and used on a large scale. The super-hydrophobic layer has a water contact angle of 150-165 degrees and a rolling angle less than 5 degrees. The super-hydrophobic layer has stable performance, low cost and excellent mechanical property and is applicable to places requiring water proofing, antifouling, fog proofing, snow coating proofing, ice coating proofing and oxidation proofing. The thermoplastic membrane matrix is used, therefore, the super-hydrophobic membrane can be flexibly used. The super-hydrophobic membrane can be manufactured into a tape structure to be adhered on surfaces of other matrices. The super-hydrophobic membrane is convenient and simple in use, easy to popularize and is a super-hydrophobic structure which can be manufactured and used on a large scale.