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发明公开
CN101553573A 包含乙内酰脲酶、消旋酶和氨甲酰基水解酶的全细胞催化体系 无效 - 撤回

包含乙内酰脲酶、消旋酶和氨甲酰基水解酶的全细胞催化体系
摘要：
本发明涉及用于从相应的乙内酰脲制备对映异构体富集的α－氨基酸的全细胞催化体系，其中在重组的微生物中共同表达乙内酰脲酶、L－氨甲酰基水解酶和乙内酰脲消旋酶，其中编码这三种酶的基因位于单个复制子上。本发明还相应地涉及这类全细胞催化体系在从相应的乙内酰脲制备对映异构体富集的L－α－氨基酸中的用途。
摘要（英）：

The present invention relates to a whole cell catalytic system for the preparation of an enantiomerically enriched alpha-amino acid from a corresponding hydantoin wherein hydantoinase, L-carbamoylase and hydantoin racemase are coexpressed in a recombinant micro-organism wherein the genes coding for these three enzymes are located on a single replicon. The present invention further relates to the use of such a whole cell catalytic system according in the preparation of an enantiomerically enriched L-alpha-amino acid from a corresponding hydantoin.

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