The invention provides a real-time measurement method of dynamic radius and a dynamic misalignment angle of a precision centrifuge and a device thereof, wherein, 8 capacitance sensors are arranged outside the edge of the table top and on the shaft end of the centrifuge to respectively point to a mounting block of a measured piece on the table top and the datum plane on the shaft end. The method comprises the following steps: accessing the output signal of the capacitance sensors to a data acquisition board of an industrial personal computer, taking a pulse signal of an angle encoder of the centrifuge after frequency division as a sampling trigger signal so as to guarantee the sampling points of each ring at the same position; allowing the centrifuge to continuously rotate with a lower speed to measure a static value; allowing the centrifuge to rotate with a high speed to measure a dynamic value; and subtracting the static value corresponding to the angle by the dynamic value to obtaindynamic variation and the dynamic misalignment angle of the table top of the centrifuge after calculation.