The invention relates to a nano hybridized hydrogel which can be used as a tooth root canal filling material. The organic/inorganic nano hybridized hydrogel for the tooth root canal filling material is formed by polymerizing a silane coupling agent modified inorganic nano particle, a monomer, an initiating agent and a cross-linking agent, wherein the inorganic nano particle is a mixed nano particle of ZnO and ZrO2; and the monomer is an amide or ester water-soluble organic compound. The organic/inorganic nano hybridized hydrogel has specific swelling performance, favorable biocompatibility, excellent stability and favorable service behaviour, no toxic and side effect and durable antibiosis and can thoroughly eliminate phenomena of microgaps and coronal leakage of the traditional root canalmaterial caused by polymerization shrinkage, be convenient to disinfect, use and remove and achieve X-ray radiation resistance so as to be convenient for examination. In addition, compared with the traditional gel material, the gel is greatly improved on mechanical performance and has high application value.