The invention discloses an implement method of power control cognition MAC protocol based on time division multiple access (TDMA). The method comprises the following steps: adopting strict time slot division, finishing time slot allocation among node pairs by a three-way handshake manner, namely, reserving application, reserving confirmation and deciding sending; realizing collision-free transmission in node communication process; and introducing a power control mechanism to improve the reuse rate of cyber space. The method can eliminate problems of multiple channels hiding a send terminal, multiple channels hiding a receiving terminal and multiple channels exposing terminals, and can dramatically decrease the impact on network performance brought by the problem of multiple channels hiding the send terminal. The simulation result indicates, compared with dynamic spectrum access MAC (DSA-MAC) protocol, the invention can effectively enhance network throughput and decrease access time delay with the increment of network business volume.