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发明公开
CN101659629A 鱼腥草素类高水溶性、稳定性前体药物及其制备方法与运用 无效 - 撤回

鱼腥草素类高水溶性、稳定性前体药物及其制备方法与运用
摘要：
本发明公开了一种鱼腥草素类高水溶性、稳定性前体药物及其制备方法和在制药中的运用。该前体药物符合通式(I)、(II)、(III)、(IV)。其制备方法是将氨氧乙酸或氨氧乙胺与相对应的母体药物在适宜的溶剂中进行肟化反应即可。该前体药物可进行多种药物剂型的制备。具有高水溶性、高稳定性、效果好、毒副作用低的优点。
摘要（英）：

The invention discloses a houttuynin high water-solubility and stability prodrug and a preparing method and application thereof in preparing drug. The prodrug conforms to the general formulas (I), (II), (III) and (IV). The preparing method is characterized in that aminoxyacetic acid or aminoxyacetic amine reacts with corresponding parent drug in suitable solvent for oximation reaction. The prodrugcan prepare various drug forms and has the advantages of high water solubility, high stability, favorable effect and low toxic or side effect.

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