The invention relates to a method for preparing potato starch medicament carrier microspheres, which comprises the following steps: (1) mixing potato native starch with water to form a starch emulsion with the emulsion concentration of 3.5 to 5.0g/100ml, and adjusting the pH value to between 8 and 11; (2) performing constant temperature gelatinization on the starch emulsion to obtain a gelatinized starch emulsion; (3) adding edible oil and an emulsifying agent into the starch emulsion respectively to prepare a reversed phase emulsion; and (4) adding a crosslinking agent, sodium bisulfite and ammonium persulfate into the reversed phase emulsion respectively to perform reactions, adjusting the pH to between 8 to 11, then standing the mixture, removing the supernatant fluid, washing, drying and crushing the mixture, and passing the powder through a sieve of 80 meshes. The method has a simple production process and simple operation and is easy to grasp, the production cost is low, the pollution is less, and the potato starch medicament carrier produced by the method has a long slow-release time and a high slow-release rate.