The invention relates to a regeneration process for washing and spraying methanol by low-temperature methanol, which comprises the following steps of: spraying the methanol by virgin gas, cooling the virgin gas, carrying out gas-liquid separation on the virgin gas, carrying out flash evaporation on the methanol and a water condensate, reheating the methanol and the water condensate, rectifying and regenerating the methanol, carrying out flash evaporation on the methanol sprayed by the virgin gas and the water condensate by a flash tank, delivering the flashed vapor of the condensate into an H2S concentration tower, delivering into tail gas finally, carrying out heat exchange between the decompressed methanol, the decompressed water condensate and H2S gas at an outlet of an H2S distillate heat exchanger, delivering the reheated methanol and the reheated water condensate into a methanol water knockout tower for separation, delivering methanol gas at the top of the methanol water knockout tower into a methanol regeneration tower and carrying out rectification and regeneration. Compared with the prior art, the invention has the advantages of low energy consumption, low operating pressure of the heat exchanger, high concentration of H2S in acid gas and the like.