The invention discloses a new medicine for treating generalized anxiety and a preparation method thereof. The medicine uses radix bupleuri, radices paeoniae alba, red sage root, and the like as raw materials. According to the different physical and chemical properties of active ingredients of each traditional Chinese medicine, the traditional Chinese medicines are processed in different physical or chemical methods to prepare a clinically acceptable dosage form. The medicine has unique formula, is clinically used for generalized anxiety, and has significant effect.