利索-全球专利检索

  1. 登录
  2. 注册
发明授权
CN101812079B 一种含多硫键的哌嗪类化合物及其制备方法和用途 有权

一种含多硫键的哌嗪类化合物及其制备方法和用途
摘要：
本发明涉及一种含多硫键的哌嗪类化合物的制备方法和用途。本发明用分离自南极长城站土壤样品的真菌Oidiodendron truncatum GW3-13生产出结构新颖的含多硫键的哌嗪类化合物。经实验证实，该类化合物可作为细胞增殖抑制剂或缺氧诱导因子-1(hypoxiainducible factor 1，HIF-1)靶向抗肿瘤剂。
摘要（英）：

The invention relates to a preparation method of a piprazine compound containing polysulfide bond and an application thereof. Fungus oidiodendron truncatum GW3-13 which is separated from the soil of Antarctic Great Wall Station is used for producing the piprazine compound containing the polysulfide bond with novel structure. The piprazine compound is proved to be used as cell proliferation inhibitor or hypoxia-inducible factor-1 (HIF-1) targeting antineoplastic agent.

公开/授权文献
0/0