The invention relates to a refining method of 1-(4-hydroxylphengl)-2-bromopropane-1-ketone, which is an ifenprodil bromo-intermediate. The refining method comprises the following steps of: dissolving a 1-(4-hydroxylphengl)-2-bromopropane-1-ketone crude product into ether, reversely dripping with a reversible solvent, such as petroleum ether, stirring at low speed to separate out white solid, and filtering to prepare the 1-(4-hydroxylphengl)-2-bromopropane-1-ketone pure product.