The invention relates to a bioreactor for producing ethanol by using lignocellulose materials with high solid content, which at least comprises a tank body; a feeder comprises a rubbing unit, the tank body is provided with a charge opening, a discharge opening, a sterile air inlet, a gas disperser and a sensor jack. An anti-spiral screw belt is located at the upper part of the combined agitator blade and the direction of the screw belt is opposite to that of the screw belt of the combined agitator blade. The invention has the advantages that the enzymolysis and fermentation efficiencies of the lignocellulose materials which are rubbed by the feeder are increased, the combined agitator blade ensures that the materials in the tank body are mixed adequately, and transfer mass and heat, the anti-spiral screw belt eliminates the high viscosity bubble or bubble layer generated by the system immediately, parameters are measured accurately under the condition that the positioning way of the sensor does not influence the full mixing and transferring of the system; and the gas disperser disperses the gas introduced to the tank under the condition of not influencing that the system is adequately mixed and transferred.