The invention relates to a calamine cellulose fiber, which is characterized in that the formed calamine cellulose fiber is obtained through the following processes: preparing calamine slurry, preparing a spinning solution, preparing a denatured spinning solution and spinning; the weight percentage of the calamine in the finished product calamine cellulose fiber is 5% to 25%; the yarn is dissolvedby adopting ionic liquid so as to increase the dissolubility of the yarn and enhance the production efficiency; a large amount of hydrogen sulfide and carbon disulfide can be avoided from generating in the yellowing process when the traditional viscose process is adopted; the environment pollution is reduced; the damage on the health of operation personnel is lightened; the ionic liquid is adopted to serve as a coagulating bath solution so as to guarantee that the effective components in the calamine are not damaged; the functional index of the finished product fiber is enhanced; the wet-dry strength and the dry extension are obviously enhanced; and the bleaching process in the course of preparing the conventional spinning solution fiber in the postprocessing process is omitted so as to avoid the damage of bleaching substances on the calamine and antibiosis active substances in the calamine.