The invention relates to a fixture for drilling inflating and discharging holes in a hub, which comprises a body, a revolution body, a rotating shaft, housing screws, a locating ring, a locating pin, a drilling template, a b-type drilling template, a hook clamp plate and a localizer. The revolution body is a U-shaped frame body, and both sides of the revolution body are connected with the body through the rotating shaft and an adjusting washer. The housing screws are symmetrically arranged on both sides of the body with three screws on each side, wherein two screws in each side are distributed in a horizontal position and the third screw is vertical to the horizontal plane. By adopting a rotation design, three working procedures are merged into one working procedure, and three holes are processed with a set of fixture and a drilling machine, thus reducing fixturing frequency, saving time and labor, and improving labor efficiency.