A multi-function shower head structure includes a connection base, a valve bolt, a guide bolt, a housing and a plurality of spray units. The connection base is used to connect external water and is connected with the valve bolt. The guide bolt is pivoted to the valve bolt. The guide bolt has an axial conducting hole and a guide channel to communicate with the conducting hole. The conducting hole can be rotated about the valve bolt, such that the valve bolt guides the water of the connection base to the conducting hole of the guide bolt for a guide channel to output water. The housing has a hole seat. The hole seat has a pivot hole for connection of the guide bolt. The spray units are disposed in the housing. Each spray unit has a water chamber. The guide channel of the hole seat has a plurality of spaced branch channels corresponding to the respective water chambers to communicate with the pivot hole. When the housing is turned about the guide bolt, the branch channels are changed to communicate with the guide channel for different spray modes, providing a user-friendly effect.