The invention relates to a preparation for socks capable of eliminating foot smell and preventing dermatophytosis, belonging to a chemical industry. The preparation is prepared from the following components in percentage by weight: pure water, methenamine powder, nutgall powder, tourmaline powder, natural latex (liquid) and dry casein (powder) which are mixed into a micro-emulsion liquid preparation, and the product is used for producing health socks capable of eliminating foot smell and preventing dermatophytosis. A preparation method of the preparation comprises the following steps of: adding a solution in a stainless steel container; then, soaking a pair of finished socks in the container; and heating to 50 DEG C-60 DEG C for 90 min. The preparation is prepared from the following composition raw materials in percentage by weight: 60-75 percent of pure water, 10-20 percent of methenamine powder, 5-12 percent of nutgall powder, 4-6 percent of tourmaline powder, 1-3 percent of natural latex and 0.5-1 percent of dry casein. The preparation disclosed by the invention can eliminate foot smell and prevent dermatophytosis and is suitable for various crowds with foot smell and dermatophytosis, and the liquid of the preparation does not pollute environment and has higher application values.