The invention provides a valve flange multishaft drilling device with high processing efficiency. In the valve flange multishaft drilling device, guide columns which are parallel to drill bits are arranged on a machine body of a drilling machine; limit rings are fixed at the lower ends of the guide columns; bushing plates are slidably arranged on the guide columns; elastic components which can ensure that the bushing plates and the limit rings are contacted in the normal state are arranged between the bushing plates and the machine body; each bushing plate is provided with a plurality of drill bushings; the lower part of each bushing plate is provided with a positioning hole for positioning a flange; and a plurality of drill bits which correspond to the drill bushings and drill the flanges are arranged above the bushing plates.